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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2021

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
−6 vs. Q2 2021
Shares held
46.4M
+694.4K (+1.5%) vs. Q2 2021
Total value
$820.8M
−$1.22B (−59.9%) vs. Q2 2021
New holders
25
59 more added
Sold out
31
34 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 132 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2021: $820.8M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2021.

Institutions holding PTGX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Metropolitan Life Insurance Co11,747$208.2K0.00%+195+1.7%Added
Bingham Osborn & Scarborough LLC11,640$206.0K0.01%00.0%Unchanged
State Board of Administration of Florida Retirement System10,828$192.0K0.00%+380+3.6%Added
Arizona State Retirement System10,773$191.0K0.00%+74+0.7%Added
Walleye Capital LLC10,116$179.0K0.01%+10,116New
SG3 Management, LLC10,000$177.0K0.06%+10,000New
BNP Paribas Arbitrage, SA8,007$141.9K0.00%+6,406+400.1%Added
Virtus ETF Advisers LLC5,170$92.0K0.04%−271−5.0%Reduced
Kessler Investment Group, LLC5,165$92.0K0.07%+5,165New
Royal Bank of Canada4,785$85.0K0.00%+1,455+43.7%Added
Ameritas Investment Partners, Inc.3,241$57.0K0.00%00.0%Unchanged
Lindbrook Capital, LLC2,450$43.0K0.01%+2,000+444.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)2,429$43.0K0.00%+2,429New
O'Shaughnessy Asset Management, LLC2,162$38.0K0.00%−241−10.0%Reduced
Great West Life Assurance Co1,982$35.0K0.00%00.0%Unchanged
Group One Trading, L.P.1,800$32.0K0.00%+1,800New
Eagle Bay Advisors LLC1,240$22.0K0.01%+240+24.0%Added
Cubist Systematic Strategies, LLC1,117$20.0K0.00%−2,783−71.4%Reduced
Penserra Capital Management LLC1,090$19.0K0.00%+90+9.0%Added
Nisa Investment Advisors, LLC450$8.00K0.00%00.0%Unchanged
Macquarie Group Ltd307$5.00K0.00%00.0%Unchanged
US Bancorp264$4.00K0.00%−91−25.6%Reduced
Truvestments Capital LLC250$4.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.163$3.00K0.00%+82+101.2%Added
TCI Wealth Advisors, Inc.146$3.00K0.00%+51+53.7%Added
Harbour Investments, Inc.126$2.00K0.00%+51+68.0%Added
Advisor Group Holdings, Inc.57$1.00K0.00%−173−75.2%Reduced
Signaturefd, LLC46$1.00K0.00%00.0%Unchanged
Captrust Financial Advisors43$1.00K0.00%+43New
Cutler Group LP100$1.00K0.00%+100New
State of Wyoming26$00.00%−95−78.5%Reduced
Ellevest, Inc.6$00.00%+6New
Consonance Capital Management LP0$00.00%−3,446,874−100.0%Sold out
Victory Capital Management Inc0$00.00%−845,199−100.0%Sold out
Novo Holdings A/S0$00.00%−600,010−100.0%Sold out
Loomis Sayles & Co L P0$00.00%−536,920−100.0%Sold out
Baker Bros. Advisors LP0$00.00%−455,276−100.0%Sold out
Tri Locum Partners LP0$00.00%−341,650−100.0%Sold out
Laurion Capital Management LP0$00.00%−337,109−100.0%Sold out
Pinz Capital Management, LP0$00.00%−196,000−100.0%Sold out
International Biotechnology Trust PLC0$00.00%−152,000−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−140,100−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−138,608−100.0%Sold out
Parkman Healthcare Partners LLC0$00.00%−130,000−100.0%Sold out
Emerald Advisers, LLC0$00.00%−103,850−100.0%Sold out
EAM Investors, LLC0$00.00%−101,019−100.0%Sold out
Iszo Capital Management LP0$00.00%−93,883−100.0%Sold out
Emerald Mutual Fund Advisers Trust0$00.00%−76,965−100.0%Sold out
EAM Global Investors LLC0$00.00%−70,185−100.0%Sold out
Gyon Technologies Capital Management, LP0$00.00%−35,056−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−33,230−100.0%Sold out
Monashee Investment Management LLC0$00.00%−20,000−100.0%Sold out
J. Goldman & Co LP0$00.00%−19,986−100.0%Sold out
Principal Financial Group Inc0$00.00%−16,540−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−13,939−100.0%Sold out
Amalgamated Bank0$00.00%−7,807−100.0%Sold out
Winton Group Ltd0$00.00%−5,431−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−5,000−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−4,793−100.0%Sold out
Engineers Gate Manager LP0$00.00%−4,710−100.0%Sold out
FORA Capital, LLC0$00.00%−2,731−100.0%Sold out
Hartford Financial Management Inc.0$00.00%−300−100.0%Sold out
IFP Advisors, Inc0$00.00%−8−100.0%Sold out
Johnson & Johnson Innovation - JJDC, Inc.––––Not filed