Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 137
- +5 vs. Q3 2022
- Shares held
- 48.9M
- +1.68M (+3.5%) vs. Q3 2022
- Total value
- $533.3M
- +$135.4M (+34.0%) vs. Q3 2022
- New holders
- 21
- 51 more added
- Sold out
- 16
- 43 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Franklin Resources Inc | 14,748 | $160.9K | 0.00% | +14,748 | New |
| Legal & General Group Plc | 14,408 | $157.2K | 0.00% | +1,118+8.4% | Added |
| Obermeyer Wood Investment Counsel, LLLP | 14,350 | $156.6K | 0.01% | −958−6.3% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 14,318 | $156.2K | 0.02% | −7,077−33.1% | Reduced |
| Virtus ETF Advisers LLC | 14,235 | $155.3K | 0.08% | −20.0% | Reduced |
| DekaBank Deutsche Girozentrale | 15,800 | $154.0K | 0.00% | 00.0% | Unchanged |
| DuPont Capital Management Corp | 13,127 | $143.2K | 0.01% | +13,127 | New |
| XTX Topco Ltd | 12,942 | $141.2K | 0.03% | −25,882−66.7% | Reduced |
| Principal Financial Group Inc | 11,738 | $128.1K | 0.00% | +1,389+13.4% | Added |
| State Board of Administration of Florida Retirement System | 11,323 | $123.5K | 0.00% | +360+3.3% | Added |
| Teacher Retirement System of Texas | 11,128 | $121.0K | 0.00% | −818−6.8% | Reduced |
| American Century Companies Inc | 11,056 | $120.6K | 0.00% | +11,056 | New |
| Mariner, LLC | 10,649 | $116.0K | 0.00% | −2,458−18.8% | Reduced |
| Arizona State Retirement System | 10,387 | $113.3K | 0.00% | +10,387 | New |
| Alpine Global Management, LLC | 10,279 | $112.0K | 0.04% | +10,279 | New |
| Occudo Quantitative Strategies LP | 10,198 | $111.3K | 0.01% | −10,689−51.2% | Reduced |
| Acadian Asset Management LLC | 9,199 | $100.0K | 0.00% | −128,001−93.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,536 | $93.1K | 0.00% | +1,337+18.6% | Added |
| Quantbot Technologies LP | 6,700 | $73.1K | 0.01% | +5,700+570.0% | Added |
| Lazard Asset Management LLC | 6,404 | $69.0K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 5,903 | $64.4K | 0.00% | −5,784−49.5% | Reduced |
| Amalgamated Bank | 5,765 | $63.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,543 | $60.0K | 0.00% | +4,732+583.5% | Added |
| Ameritas Investment Partners, Inc. | 3,501 | $40.2K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,921 | $31.9K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 1,982 | $22.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,049 | $22.0K | 0.00% | +49+2.5% | Added |
| Tower Research Capital LLC (TRC) | 1,747 | $19.0K | 0.00% | −25,407−93.6% | Reduced |
| Group One Trading, L.P. | 1,307 | $14.3K | 0.00% | −20,956−94.1% | Reduced |
| Global Retirement Partners, LLC | 1,000 | $10.9K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 500 | $5.46K | 0.00% | +40+8.7% | Added |
| Leonteq Securities AG | 470 | $5.13K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 345 | $3.76K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 163 | $2.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 37 | $404 | 0.00% | −2,307−98.4% | Reduced |
| Sofos Investments, Inc. | 11 | $197 | 0.00% | +11 | New |
| Covestor Ltd | 10 | $0 | 0.00% | −1−9.1% | Reduced |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −232,820−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −53,443−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −53,190−100.0% | Sold out |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −48,977−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −33,498−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −31,814−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −27,275−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −24,332−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −22,421−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −12,270−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −12,084−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −1,582−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −1,112−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −755−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | 0 | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −387−100.0% | Sold out |
| Jefferies Group LLC | – | – | – | – | Not filed |