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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
157
+14 vs. Q3 2023
Shares held
57.5M
+792.3K (+1.4%) vs. Q3 2023
Total value
$1.32B
+$372.5M (+39.4%) vs. Q3 2023
New holders
33
40 more added
Sold out
19
60 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 157 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ4 2023: $1.32B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2023.

Institutions holding PTGX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd5$00.00%00.0%Unchanged
Gradient Investments LLC1$230.00%00.0%Unchanged
The PNC Financial Services Group, Inc.5$1150.00%−110−95.7%Reduced
Principal Securities, Inc.6$1380.00%+6New
GAMMA Investing LLC25$6250.00%+25New
Farther Finance Advisors, LLC40$9170.00%+40New
Northwestern Mutual Wealth Management Co100$2.29K0.00%+100New
Truvestments Capital LLC131$3.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.163$4.00K0.00%00.0%Unchanged
Comerica Bank227$5.21K0.00%+227New
Advisor Group Holdings, Inc.281$6.43K0.00%−31−9.9%Reduced
Global Retirement Partners, LLC300$7.39K0.00%00.0%Unchanged
Quarry LP750$17.2K0.01%+750New
Amundi2,032$51.6K0.00%−1,687−45.4%Reduced
STRS Ohio2,400$55.0K0.00%−9,600−80.0%Reduced
Allspring Global Investments Holdings, LLC2,533$58.1K0.00%−5,973−70.2%Reduced
Nisa Investment Advisors, LLC2,639$60.5K0.00%00.0%Unchanged
Simplex Trading, LLC2,834$64.0K0.00%+2,834New
Metropolitan Life Insurance Co3,352$76.9K0.00%00.0%Unchanged
EntryPoint Capital, LLC3,696$84.7K0.08%+3,696New
Virtus ETF Advisers LLC4,457$102.2K0.06%+1,017+29.6%Added
Great West Life Assurance Co5,213$119.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.5,912$135.6K0.00%+526+9.8%Added
China Universal Asset Management Co., Ltd.6,675$153.1K0.03%+5,202+353.2%Added
Amalgamated Bank6,861$157.0K0.00%+100+1.5%Added
US Bancorp7,167$164.3K0.00%−2,743−27.7%Reduced
Aquatic Capital Management LLC8,700$199.0K0.01%+200+2.4%Added
E Fund Management Co., Ltd.8,957$205.4K0.01%−9,034−50.2%Reduced
Los Angeles Capital Management LLC9,154$209.9K0.00%+9,154New
Mariner, LLC9,254$212.2K0.00%−5,288−36.4%Reduced
AQR Capital Management LLC9,342$214.2K0.00%−1,124−10.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,338$237.1K0.00%+1,093+11.8%Added
Teacher Retirement System of Texas10,640$244.0K0.00%−2,314−17.9%Reduced
Cerity Partners LLC11,265$258.3K0.00%00.0%Unchanged
Bridgefront Capital, LLC11,370$260.7K0.20%+11,370New
Franklin Street Advisors Inc11,720$269.0K0.02%00.0%Unchanged
Tower Research Capital LLC (TRC)11,759$269.6K0.00%+4,037+52.3%Added
Brevan Howard Capital Management LP11,806$270.7K0.03%+11,806New
King Wealth12,000$275.0K0.05%00.0%Unchanged
Obermeyer Wood Investment Counsel, LLLP12,066$276.7K0.02%−1,726−12.5%Reduced
Chartwell Investment Partners, LLC12,098$277.0K0.01%−1,646−12.0%Reduced
Engineers Gate Manager LP12,522$287.1K0.01%−13,332−51.6%Reduced
Bayesian Capital Management, LP12,661$290.3K0.03%+12,661New
Arizona State Retirement System12,866$295.0K0.00%−175−1.3%Reduced
ProShare Advisors LLC13,139$301.3K0.00%+1,957+17.5%Added
DekaBank Deutsche Girozentrale15,800$326.0K0.00%00.0%Unchanged
Principal Financial Group Inc14,429$330.9K0.00%−542−3.6%Reduced
Nebula Research & Development LLC15,286$350.5K0.11%+15,286New
Wells Fargo & Company16,157$370.5K0.00%−60,407−78.9%Reduced
State Board of Administration of Florida Retirement System16,303$373.8K0.00%00.0%Unchanged
Corton Capital Inc.16,428$376.7K0.12%+16,428New
CWM Advisors, LLC16,782$384.8K0.04%−1,828−9.8%Reduced
Royal Bank of Canada17,455$400.0K0.00%+9,396+116.6%Added
Skandinaviska Enskilda Banken AB (publ)18,914$433.7K0.00%00.0%Unchanged
Gsa Capital Partners LLP19,788$454.0K0.04%+19,788New
Schroder Investment Management Group19,900$456.3K0.00%+19,900New
Janus Henderson Group PLC21,734$498.6K0.00%−41−0.2%Reduced
New York State Common Retirement Fund23,103$529.8K0.00%−98−0.4%Reduced
Twinbeech Capital LP24,161$554.0K0.01%−123,185−83.6%Reduced
Profund Advisors LLC27,890$639.5K0.03%−30,826−52.5%Reduced
HighVista Strategies LLC28,359$650.3K0.24%+28,359New
American International Group, Inc.28,390$651.0K0.00%−115−0.4%Reduced
Ensign Peak Advisors, Inc28,400$651.2K0.00%00.0%Unchanged
MetLife Investment Management28,596$655.7K0.00%00.0%Unchanged
Tudor Investment Corp Et Al28,786$660.1K0.01%+28,786New
AlphaCentric Advisors LLC30,000$687.9K0.46%−13,500−31.0%Reduced
Bellevue Group AG30,000$687.9K0.01%00.0%Unchanged
Fox Run Management, L.L.C.31,275$717.1K0.18%+31,275New
Mirae Asset Global Investments Co., Ltd.31,759$728.2K0.00%−5,463−14.7%Reduced
Hennion & Walsh Asset Management, Inc.34,046$780.7K0.04%+2,380+7.5%Added
SEI Investments Co37,229$853.7K0.00%−2,987−7.4%Reduced
American Century Companies Inc38,344$879.2K0.00%+38,344New
State of Wisconsin Investment Board39,799$912.6K0.00%−21,682−35.3%Reduced
Alps Advisors Inc40,072$918.9K0.01%−2,377−5.6%Reduced
Voya Investment Management LLC43,245$991.6K0.00%+282+0.7%Added
Legal & General Group Plc45,289$1.04M0.00%+524+1.2%Added
Invesco Ltd.45,763$1.05M0.00%+4,862+11.9%Added
Citadel Advisors LLC47,864$1.10M0.00%−2,932−5.8%Reduced
Birchview Capital, LP48,000$1.10M0.86%+10,000+26.3%Added
California State Teachers Retirement System50,392$1.16M0.00%−2,688−5.1%Reduced
Balyasny Asset Management LLC50,503$1.16M0.00%+50,503New
Knott David M Jr52,368$1.20M0.46%00.0%Unchanged
Readystate Asset Management LP57,206$1.31M0.08%−127,141−69.0%Reduced
Moody Aldrich Partners LLC62,327$1.43M0.26%−6,641−9.6%Reduced
Credit Suisse AG62,517$1.43M0.00%+12,404+24.8%Added
Manufacturers Life Insurance Company, The68,432$1.57M0.00%−5,691−7.7%Reduced
BNP Paribas Arbitrage, SA71,898$1.65M0.00%−72,066−50.1%Reduced
Citigroup Inc72,703$1.67M0.00%−75,125−50.8%Reduced
Jane Street Group, LLC72,931$1.67M0.00%+34,425+89.4%Added
HRT Financial LP73,126$1.68M0.01%+73,126New
Algert Global LLC75,760$1.74M0.07%+2,930+4.0%Added
Boothbay Fund Management, LLC80,607$1.85M0.07%+80,607New
Soleus Capital Management, L.P.83,000$1.90M0.21%+83,000New
Rhumbline Advisers83,292$1.91M0.00%+483+0.6%Added
Alliancebernstein L.P.85,400$1.96M0.00%−1,872−2.1%Reduced
Schonfeld Strategic Advisors LLC89,113$2.04M0.02%−64,985−42.2%Reduced
Swiss National Bank90,700$2.08M0.00%−9,900−9.8%Reduced
Great Lakes Advisors, LLC91,153$2.09M0.02%−50,406−35.6%Reduced
UBS Oconnor LLC106,154$2.43M0.08%−30,114−22.1%Reduced
Connor, Clark & Lunn Investment Management Ltd.107,542$2.47M0.01%−31,952−22.9%Reduced