Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 157
- +14 vs. Q3 2023
- Shares held
- 57.5M
- +792.3K (+1.4%) vs. Q3 2023
- Total value
- $1.32B
- +$372.5M (+39.4%) vs. Q3 2023
- New holders
- 33
- 40 more added
- Sold out
- 19
- 60 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 21,734 | $498.6K | 0.00% | −41−0.2% | Reduced |
| Schroder Investment Management Group | 19,900 | $456.3K | 0.00% | +19,900 | New |
| Gsa Capital Partners LLP | 19,788 | $454.0K | 0.04% | +19,788 | New |
| Skandinaviska Enskilda Banken AB (publ) | 18,914 | $433.7K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 17,455 | $400.0K | 0.00% | +9,396+116.6% | Added |
| CWM Advisors, LLC | 16,782 | $384.8K | 0.04% | −1,828−9.8% | Reduced |
| Corton Capital Inc. | 16,428 | $376.7K | 0.12% | +16,428 | New |
| State Board of Administration of Florida Retirement System | 16,303 | $373.8K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 16,157 | $370.5K | 0.00% | −60,407−78.9% | Reduced |
| Nebula Research & Development LLC | 15,286 | $350.5K | 0.11% | +15,286 | New |
| Principal Financial Group Inc | 14,429 | $330.9K | 0.00% | −542−3.6% | Reduced |
| DekaBank Deutsche Girozentrale | 15,800 | $326.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 13,139 | $301.3K | 0.00% | +1,957+17.5% | Added |
| Arizona State Retirement System | 12,866 | $295.0K | 0.00% | −175−1.3% | Reduced |
| Bayesian Capital Management, LP | 12,661 | $290.3K | 0.03% | +12,661 | New |
| Engineers Gate Manager LP | 12,522 | $287.1K | 0.01% | −13,332−51.6% | Reduced |
| Chartwell Investment Partners, LLC | 12,098 | $277.0K | 0.01% | −1,646−12.0% | Reduced |
| Obermeyer Wood Investment Counsel, LLLP | 12,066 | $276.7K | 0.02% | −1,726−12.5% | Reduced |
| King Wealth | 12,000 | $275.0K | 0.05% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 11,806 | $270.7K | 0.03% | +11,806 | New |
| Tower Research Capital LLC (TRC) | 11,759 | $269.6K | 0.00% | +4,037+52.3% | Added |
| Franklin Street Advisors Inc | 11,720 | $269.0K | 0.02% | 00.0% | Unchanged |
| Bridgefront Capital, LLC | 11,370 | $260.7K | 0.20% | +11,370 | New |
| Cerity Partners LLC | 11,265 | $258.3K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 10,640 | $244.0K | 0.00% | −2,314−17.9% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,338 | $237.1K | 0.00% | +1,093+11.8% | Added |
| AQR Capital Management LLC | 9,342 | $214.2K | 0.00% | −1,124−10.7% | Reduced |
| Mariner, LLC | 9,254 | $212.2K | 0.00% | −5,288−36.4% | Reduced |
| Los Angeles Capital Management LLC | 9,154 | $209.9K | 0.00% | +9,154 | New |
| E Fund Management Co., Ltd. | 8,957 | $205.4K | 0.01% | −9,034−50.2% | Reduced |
| Aquatic Capital Management LLC | 8,700 | $199.0K | 0.01% | +200+2.4% | Added |
| US Bancorp | 7,167 | $164.3K | 0.00% | −2,743−27.7% | Reduced |
| Amalgamated Bank | 6,861 | $157.0K | 0.00% | +100+1.5% | Added |
| China Universal Asset Management Co., Ltd. | 6,675 | $153.1K | 0.03% | +5,202+353.2% | Added |
| Ameritas Investment Partners, Inc. | 5,912 | $135.6K | 0.00% | +526+9.8% | Added |
| Great West Life Assurance Co | 5,213 | $119.0K | 0.00% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 4,457 | $102.2K | 0.06% | +1,017+29.6% | Added |
| EntryPoint Capital, LLC | 3,696 | $84.7K | 0.08% | +3,696 | New |
| Metropolitan Life Insurance Co | 3,352 | $76.9K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 2,834 | $64.0K | 0.00% | +2,834 | New |
| Nisa Investment Advisors, LLC | 2,639 | $60.5K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 2,533 | $58.1K | 0.00% | −5,973−70.2% | Reduced |
| STRS Ohio | 2,400 | $55.0K | 0.00% | −9,600−80.0% | Reduced |
| Amundi | 2,032 | $51.6K | 0.00% | −1,687−45.4% | Reduced |
| Quarry LP | 750 | $17.2K | 0.01% | +750 | New |
| Global Retirement Partners, LLC | 300 | $7.39K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 281 | $6.43K | 0.00% | −31−9.9% | Reduced |
| Comerica Bank | 227 | $5.21K | 0.00% | +227 | New |
| Daiwa Securities Group Inc. | 163 | $4.00K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 131 | $3.00K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 100 | $2.29K | 0.00% | +100 | New |
| Farther Finance Advisors, LLC | 40 | $917 | 0.00% | +40 | New |
| GAMMA Investing LLC | 25 | $625 | 0.00% | +25 | New |
| Principal Securities, Inc. | 6 | $138 | 0.00% | +6 | New |
| The PNC Financial Services Group, Inc. | 5 | $115 | 0.00% | −110−95.7% | Reduced |
| Gradient Investments LLC | 1 | $23 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 5 | $0 | 0.00% | 00.0% | Unchanged |
| Cowen and Company, LLC | 0 | $0 | 0.00% | −1,657,551−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −1,109,150−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −320,000−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −177,125−100.0% | Sold out |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −108,308−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −91,735−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −88,000−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −60,234−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −56,577−100.0% | Sold out |
| Ghisallo Capital Management LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Public Sector Pension Investment Board | 0 | $0 | 0.00% | −49,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −35,438−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −16,139−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −12,629−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −11,853−100.0% | Sold out |
| Sawtooth Solutions, LLC | 0 | $0 | 0.00% | −10,411−100.0% | Sold out |
| Bleakley Financial Group, LLC | 0 | $0 | 0.00% | −10,411−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −12−100.0% | Sold out |
| CWM, LLC | 0 | $0 | 0.00% | −7−100.0% | Sold out |
| International Biotechnology Trust PLC | – | – | – | – | Not filed |