Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 140
- −9 vs. Q4 2021
- Shares held
- 50.6M
- +1.19M (+2.4%) vs. Q4 2021
- Total value
- $1.19B
- −$490.3M (−29.1%) vs. Q4 2021
- New holders
- 20
- 54 more added
- Sold out
- 29
- 47 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 11 | $0 | 0.00% | −3−21.4% | Reduced |
| Advisor Group Holdings, Inc. | 57 | $1.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 78 | $2.00K | 0.00% | +32+69.6% | Added |
| Daiwa Securities Group Inc. | 163 | $4.00K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 307 | $7.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 470 | $11.0K | 0.00% | +192+69.1% | Added |
| Leonteq Securities AG | 470 | $11.1K | 0.00% | 00.0% | Unchanged |
| Cutler Group LP | 784 | $18.0K | 0.00% | +200+34.2% | Added |
| Eagle Bay Advisors LLC | 1,000 | $24.0K | 0.02% | 00.0% | Unchanged |
| Great West Life Assurance Co | 1,982 | $50.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,921 | $69.2K | 0.00% | −8,826−75.1% | Reduced |
| Royal Bank of Canada | 3,000 | $71.0K | 0.00% | −7,067−70.2% | Reduced |
| Ameritas Investment Partners, Inc. | 3,501 | $83.0K | 0.00% | 00.0% | Unchanged |
| Amundi | 3,855 | $98.0K | 0.00% | −198−4.9% | Reduced |
| Simplex Trading, LLC | 4,972 | $117.0K | 0.00% | +3,168+175.6% | Added |
| Kessler Investment Group, LLC | 5,165 | $122.0K | 0.07% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 5,216 | $124.0K | 0.06% | −305−5.5% | Reduced |
| Point72 Hong Kong Ltd | 5,704 | $135.0K | 0.01% | +5,704 | New |
| Tower Research Capital LLC (TRC) | 6,183 | $146.0K | 0.00% | −2,652−30.0% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,199 | $170.0K | 0.00% | +906+14.4% | Added |
| Amalgamated Bank | 7,295 | $173.0K | 0.00% | −584−7.4% | Reduced |
| Amalgamated Financial Corp. | 7,295 | $173.0K | 0.00% | +7,295 | New |
| Teacher Retirement System of Texas | 8,927 | $211.0K | 0.00% | +463+5.5% | Added |
| Gladstone Institutional Advisory LLC | 9,630 | $228.0K | 0.02% | +2,124+28.3% | Added |
| Trexquant Investment LP | 9,795 | $232.0K | 0.01% | +9,795 | New |
| E Fund Management Co., Ltd. | 10,440 | $247.0K | 0.01% | +10,440 | New |
| Ensign Peak Advisors, Inc | 10,680 | $253.0K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 10,953 | $259.0K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 11,017 | $261.0K | 0.01% | +11,017 | New |
| Parametrica Management Ltd | 11,156 | $264.0K | 0.20% | +11,156 | New |
| Arizona State Retirement System | 11,612 | $275.0K | 0.00% | +94+0.8% | Added |
| STRS Ohio | 12,700 | $300.0K | 0.00% | −500−3.8% | Reduced |
| Harvest Investment Services, LLC | 13,362 | $316.0K | 0.19% | −5,265−28.3% | Reduced |
| ProShare Advisors LLC | 13,399 | $317.0K | 0.00% | −3,090−18.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 13,700 | $325.0K | 0.00% | +13,700 | New |
| Squarepoint Ops LLC | 13,810 | $327.0K | 0.00% | −46,680−77.2% | Reduced |
| Dynamic Technology Lab Private Ltd | 15,510 | $367.0K | 0.04% | +15,510 | New |
| PDT Partners, LLC | 15,968 | $378.0K | 0.03% | −50−0.3% | Reduced |
| DekaBank Deutsche Girozentrale | 15,800 | $378.0K | 0.00% | +1,400+9.7% | Added |
| Voya Investment Management LLC | 17,368 | $411.0K | 0.00% | 00.0% | Unchanged |
| TD Asset Management Inc | 17,842 | $422.0K | 0.00% | −15,200−46.0% | Reduced |
| BNP Paribas Arbitrage, SA | 19,148 | $453.4K | 0.00% | −19,510−50.5% | Reduced |
| Renaissance Technologies LLC | 19,467 | $461.0K | 0.00% | +19,467 | New |
| Maven Securities LTD | 19,700 | $466.0K | 0.10% | +19,700 | New |
| Vontobel Holding Ltd. | 20,000 | $474.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 21,594 | $511.0K | 0.00% | +330+1.6% | Added |
| King Wealth | 22,000 | $521.0K | 0.10% | 00.0% | Unchanged |
| American International Group, Inc. | 22,210 | $526.0K | 0.00% | −1,562−6.6% | Reduced |
| Franklin Street Advisors Inc | 22,220 | $526.0K | 0.04% | 00.0% | Unchanged |
| Prudential Financial Inc | 22,993 | $544.0K | 0.00% | −7,112−23.6% | Reduced |
| Occudo Quantitative Strategies LP | 23,360 | $553.0K | 0.05% | +23,360 | New |
| MetLife Investment Management | 23,914 | $566.3K | 0.00% | +8,826+58.5% | Added |
| Algert Global LLC | 24,317 | $576.0K | 0.04% | +24,317 | New |
| Wells Fargo & Company | 26,019 | $616.0K | 0.00% | −14,339−35.5% | Reduced |
| Nisa Investment Advisors, LLC | 26,390 | $625.0K | 0.00% | −760−2.8% | Reduced |
| Allspring Global Investments Holdings, LLC | 27,306 | $646.0K | 0.00% | +1,935+7.6% | Added |
| Cubist Systematic Strategies, LLC | 28,136 | $666.0K | 0.01% | +27,590+5,053.1% | Added |
| Invesco Ltd. | 30,026 | $711.0K | 0.00% | +10,201+51.5% | Added |
| UBS Asset Management Americas Inc | 32,664 | $773.5K | 0.00% | 00.0% | Unchanged |
| Credit Suisse AG | 32,898 | $779.0K | 0.00% | +4,550+16.1% | Added |
| SG Americas Securities, LLC | 32,959 | $780.0K | 0.01% | −5,591−14.5% | Reduced |
| New York State Common Retirement Fund | 33,206 | $786.0K | 0.00% | +45+0.1% | Added |
| Walleye Capital LLC | 33,390 | $791.0K | 0.02% | −64,608−65.9% | Reduced |
| Jump Financial, LLC | 35,000 | $829.0K | 0.04% | −2,100−5.7% | Reduced |
| Citigroup Inc | 35,656 | $844.0K | 0.00% | −102,095−74.1% | Reduced |
| Birchview Capital, LP | 38,000 | $900.0K | 0.65% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 39,771 | $942.0K | 0.00% | +17,120+75.6% | Added |
| Manufacturers Life Insurance Company, The | 40,375 | $961.3K | 0.00% | +17,553+76.9% | Added |
| First Trust Advisors LP | 41,772 | $989.0K | 0.00% | +41,772 | New |
| Barclays PLC | 44,302 | $1.05M | 0.00% | −76,295−63.3% | Reduced |
| Rhumbline Advisers | 46,426 | $1.10M | 0.00% | +2,457+5.6% | Added |
| Twinbeech Capital LP | 46,825 | $1.11M | 0.05% | +46,825 | New |
| Skandinaviska Enskilda Banken AB (publ) | 48,977 | $1.16M | 0.01% | +10,673+27.9% | Added |
| Alps Advisors Inc | 49,760 | $1.18M | 0.01% | −5,472−9.9% | Reduced |
| Amitell Capital Pte Ltd | 50,129 | $1.19M | 0.86% | +50,129 | New |
| Susquehanna International Group, LLP | 50,754 | $1.20M | 0.00% | −245,659−82.9% | Reduced |
| State of Wisconsin Investment Board | 53,500 | $1.27M | 0.00% | −11,100−17.2% | Reduced |
| California State Teachers Retirement System | 56,052 | $1.33M | 0.00% | −4,413−7.3% | Reduced |
| Industrial Alliance Investment Management Inc. | 56,695 | $1.34M | 0.03% | −18,540−24.6% | Reduced |
| Engineers Gate Manager LP | 56,763 | $1.34M | 0.05% | +56,763 | New |
| Pura Vida Investments, LLC | 65,371 | $1.55M | 0.19% | +65,371 | New |
| JPMorgan Chase & Co | 69,183 | $1.64M | 0.00% | −367,270−84.1% | Reduced |
| Caption Management, LLC | 70,000 | $1.66M | 0.11% | −122,702−63.7% | Reduced |
| Voloridge Investment Management, LLC | 76,601 | $1.81M | 0.01% | −107,047−58.3% | Reduced |
| J. Goldman & Co LP | 81,873 | $1.94M | 0.15% | −48,644−37.3% | Reduced |
| Candriam Luxembourg S.C.A. | 83,646 | $1.98M | 0.01% | 00.0% | Unchanged |
| HighVista Strategies LLC | 92,045 | $2.18M | 1.39% | +61,046+196.9% | Added |
| Kennedy Capital Management, Inc. | 97,265 | $2.30M | 0.05% | −8,129−7.7% | Reduced |
| Nuveen Asset Management, LLC | 304,112 | $2.35M | 0.00% | +64,183+26.8% | Added |
| Swiss National Bank | 101,500 | $2.40M | 0.00% | +7,300+7.7% | Added |
| Silvercrest Asset Management Group LLC | 119,834 | $2.84M | 0.02% | +1,119+0.9% | Added |
| Tekla Capital Management LLC | 122,271 | $2.90M | 0.10% | +21,234+21.0% | Added |
| UBS Group AG | 122,765 | $2.91M | 0.00% | +56,454+85.1% | Added |
| Alliancebernstein L.P. | 126,463 | $3.00M | 0.00% | +80,563+175.5% | Added |
| SEI Investments Co | 130,718 | $3.10M | 0.01% | −1,595−1.2% | Reduced |
| Allianz Asset Management GmbH | 132,734 | $3.14M | 0.00% | −2,059−1.5% | Reduced |
| Twin Lakes Capital Management, LLC | 139,397 | $3.30M | 1.86% | +817+0.6% | Added |
| Bank of New York Mellon Corp | 139,769 | $3.31M | 0.00% | +1,275+0.9% | Added |
| Boothbay Fund Management, LLC | 156,641 | $3.71M | 0.12% | +156,641 | New |
| Russell Investments Group, Ltd. | 183,116 | $4.33M | 0.01% | +19,527+11.9% | Added |