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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
138
+2 vs. Q4 2022
Shares held
53.2M
+4.49M (+9.2%) vs. Q4 2022
Total value
$1.22B
+$693.0M (+130.4%) vs. Q4 2022
New holders
34
44 more added
Sold out
32
44 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 138 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ1 2023: $1.22B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2022.

Institutions holding PTGX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd10$00.00%00.0%Unchanged
The PNC Financial Services Group, Inc.115$2.65K0.00%+115New
TCI Wealth Advisors, Inc.129$2.97K0.00%+129New
Truvestments Capital LLC131$3.01K0.00%−214−62.0%Reduced
Daiwa Securities Group Inc.163$4.00K0.00%00.0%Unchanged
Caption Management, LLC243$5.59K0.00%−39,757−99.4%Reduced
Global Retirement Partners, LLC300$7.33K0.00%−700−70.0%Reduced
Leonteq Securities AG470$10.8K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.667$15.3K0.01%+167+33.4%Added
Tower Research Capital LLC (TRC)1,658$38.0K0.00%−89−5.1%Reduced
Great West Life Assurance Co1,982$46.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,049$47.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,520$58.0K0.00%−401−13.7%Reduced
Royal Bank of Canada2,634$61.0K0.00%−2,909−52.5%Reduced
Ameritas Investment Partners, Inc.3,501$80.5K0.00%00.0%Unchanged
Amalgamated Bank4,729$109.0K0.00%−1,036−18.0%Reduced
E Fund Management Co., Ltd.8,713$200.0K0.01%−6,769−43.7%Reduced
ProShare Advisors LLC8,886$204.4K0.00%+8,886New
Engineers Gate Manager LP9,278$213.4K0.01%−5,910−38.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,160$233.7K0.00%+1,624+19.0%Added
Virtus ETF Advisers LLC10,286$236.6K0.13%−3,949−27.7%Reduced
Arizona State Retirement System10,691$245.9K0.00%+304+2.9%Added
State Board of Administration of Florida Retirement System11,323$260.4K0.00%00.0%Unchanged
Teacher Retirement System of Texas11,367$261.0K0.00%+239+2.1%Added
Fred Alger Management, LLC11,605$266.9K0.00%+11,605New
Zacks Investment Management11,861$272.8K0.00%+11,861New
Cerity Partners LLC11,990$275.8K0.00%+11,990New
King Wealth12,000$276.0K0.06%−10,000−45.5%Reduced
Franklin Street Advisors Inc12,220$281.0K0.03%−30,000−71.1%Reduced
Campbell & CO Investment Adviser LLC12,425$285.8K0.05%+12,425New
Principal Financial Group Inc13,523$311.0K0.00%+1,785+15.2%Added
Obermeyer Wood Investment Counsel, LLLP13,688$314.8K0.02%−662−4.6%Reduced
Mariner, LLC14,072$324.0K0.00%+3,423+32.1%Added
Public Employees Retirement System of Ohio15,014$345.0K0.00%00.0%Unchanged
American Century Companies Inc15,617$351.2K0.00%+4,561+41.3%Added
DekaBank Deutsche Girozentrale15,800$357.0K0.00%00.0%Unchanged
Janus Henderson Group PLC17,250$397.0K0.00%+17,250New
CM Wealth Advisors LLC17,285$402.0K0.08%+17,285New
Ameriprise Financial Inc18,358$422.2K0.00%+18,358New
SG Americas Securities, LLC18,515$426.0K0.01%−38,606−67.6%Reduced
Legal & General Group Plc19,136$440.1K0.00%+4,728+32.8%Added
Algert Global LLC21,060$484.4K0.02%−63,112−75.0%Reduced
Allianz Asset Management GmbH21,500$494.5K0.00%00.0%Unchanged
American International Group, Inc.22,456$516.5K0.00%+447+2.0%Added
MetLife Investment Management23,914$550.0K0.00%00.0%Unchanged
Belvedere Trading LLC24,011$552.3K0.24%+24,011New
Mackenzie Financial Corp27,504$632.6K0.00%+27,504New
Mirae Asset Global Investments Co., Ltd.27,629$635.5K0.00%+7,752+39.0%Added
New York State Common Retirement Fund27,692$636.9K0.00%+19+0.1%Added
STRS Ohio28,500$655.0K0.00%+13,200+86.3%Added
Profund Advisors LLC28,800$662.4K0.04%+28,800New
TD Asset Management Inc29,000$667.0K0.00%+29,000New
Federated Hermes, Inc.29,653$682.0K0.00%−17,155−36.6%Reduced
Alps Advisors Inc32,415$745.5K0.01%−934−2.8%Reduced
Wells Fargo & Company33,964$781.2K0.00%+33,927+91,694.6%Added
SEI Investments Co35,639$819.7K0.00%−306−0.9%Reduced
State of Wisconsin Investment Board36,169$831.9K0.00%−76,026−67.8%Reduced
Tudor Investment Corp Et Al37,340$859.0K0.02%+37,340New
Birchview Capital, LP38,000$874.0K0.68%00.0%Unchanged
Credit Suisse AG38,001$874.0K0.00%+6,764+21.7%Added
Vontobel Holding Ltd.40,000$920.0K0.01%00.0%Unchanged
Manufacturers Life Insurance Company, The44,855$1.03M0.00%+26,337+142.2%Added
Los Angeles Capital Management LLC45,473$1.05M0.00%−31,517−40.9%Reduced
Financial Enhancement Group LLC41,818$1.06M0.21%+41,818New
FMR LLC48,320$1.11M0.00%−20,206−29.5%Reduced
California State Teachers Retirement System49,714$1.14M0.00%−988−1.9%Reduced
Alliancebernstein L.P.54,200$1.25M0.00%00.0%Unchanged
Jane Street Group, LLC56,216$1.29M0.00%+325+0.6%Added
Simplex Trading, LLC63,059$1.45M0.07%+63,059New
UBS Asset Management Americas Inc64,778$1.49M0.00%+64,778New
Cubist Systematic Strategies, LLC64,978$1.49M0.01%+13,472+26.2%Added
Prudential Financial Inc67,293$1.55M0.00%+67,293New
Jump Financial, LLC67,700$1.56M0.06%+67,700New
Rhumbline Advisers74,709$1.72M0.00%+3,556+5.0%Added
Swiss National Bank79,700$1.83M0.00%−9,200−10.3%Reduced
AXA S.A.86,500$1.99M0.01%−21,200−19.7%Reduced
Voya Investment Management LLC94,057$2.16M0.00%−45,342−32.5%Reduced
Franklin Resources Inc32,533$2.29M0.00%+17,785+120.6%Added
Russell Investments Group, Ltd.100,086$2.30M0.00%−98,883−49.7%Reduced
Thrivent Financial for Lutherans100,993$2.32M0.01%00.0%Unchanged
Walleye Trading LLC105,360$2.42M0.09%+55,851+112.8%Added
Silverarc Capital Management, LLC105,486$2.43M1.09%+105,486New
JPMorgan Chase & Co106,133$2.44M0.00%−197,029−65.0%Reduced
UBS Oconnor LLC108,473$2.49M0.06%+108,473New
Silvercrest Asset Management Group LLC113,355$2.61M0.02%−127,390−52.9%Reduced
UBS Group AG115,939$2.67M0.00%−109,590−48.6%Reduced
Connor, Clark & Lunn Investment Management Ltd.122,024$2.81M0.02%−72,680−37.3%Reduced
Susquehanna International Group, LLP124,084$2.85M0.00%+57,053+85.1%Added
Walleye Capital LLC127,370$2.93M0.06%−396,932−75.7%Reduced
Tri Locum Partners LP133,452$3.07M0.93%+133,452New
Public Sector Pension Investment Board146,000$3.36M0.03%+146,000New
Schonfeld Strategic Advisors LLC148,992$3.43M0.03%+148,992New
Great Lakes Advisors, LLC150,484$3.46M0.03%+150,484New
Rafferty Asset Management, LLC153,387$3.53M0.02%−141,961−48.1%Reduced
Bank of New York Mellon Corp168,533$3.88M0.00%+4,208+2.6%Added
Citigroup Inc192,349$4.42M0.01%+44,281+29.9%Added
D. E. Shaw & Co., Inc.199,516$4.59M0.01%+11,480+6.1%Added
Gratus Capital LLC211,731$4.87M0.37%−7,328−3.3%Reduced
Jacobs Levy Equity Management, Inc220,991$5.08M0.03%−63,124−22.2%Reduced
Allspring Global Investments Holdings, LLC223,664$5.14M0.01%+217,761+3,689.0%Added