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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
188
+4 vs. Q1 2024
Shares held
59.1M
−844.0K (−1.4%) vs. Q1 2024
Total value
$2.05B
+$313.9M (+18.1%) vs. Q1 2024
New holders
30
63 more added
Sold out
26
68 more reduced

1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 188 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2024: $2.05B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2024.

Institutions holding PTGX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
AlphaCentric Advisors LLC25,000$866.3K0.64%00.0%Unchanged
STRS Ohio24,900$862.8K0.00%+23,000+1,210.5%Added
Greenland Capital Management LP23,950$829.9K0.18%+23,950New
HighTower Advisors, LLC23,784$828.0K0.00%+23,784New
New York State Common Retirement Fund23,082$799.8K0.00%+38+0.2%Added
Toroso Investments, LLC22,062$764.4K0.01%+22,062New
Janus Henderson Group PLC21,454$743.0K0.00%−281−1.3%Reduced
HighVista Strategies LLC21,229$735.6K0.27%00.0%Unchanged
Citigroup Inc21,015$728.2K0.00%−187,626−89.9%Reduced
Skandinaviska Enskilda Banken AB (publ)18,914$655.4K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System16,303$564.9K0.00%+4,980+44.0%Added
DekaBank Deutsche Girozentrale15,800$555.0K0.00%00.0%Unchanged
Glenmede Trust Co NA15,506$537.3K0.00%+4,055+35.4%Added
Bellevue Group AG15,146$524.8K0.01%−4,000−20.9%Reduced
Tower Research Capital LLC (TRC)14,676$508.5K0.01%+14,354+4,457.8%Added
Point72 Asia (Singapore) Pte. Ltd.14,556$504.4K0.11%+14,556New
Profund Advisors LLC14,529$503.4K0.02%−22,946−61.2%Reduced
Envestnet Asset Management Inc13,559$469.8K0.00%+2,390+21.4%Added
PEAK6 Investments LLC13,303$460.9K0.02%+4,000+43.0%Added
D. E. Shaw & Co., Inc.13,152$455.7K0.00%−22,488−63.1%Reduced
Engineers Gate Manager LP12,707$440.3K0.01%−24,863−66.2%Reduced
Mariner, LLC12,283$425.6K0.00%−441−3.5%Reduced
Obermeyer Wood Investment Counsel, LLLP12,242$424.2K0.02%00.0%Unchanged
Arizona State Retirement System12,236$424.0K0.00%−445−3.5%Reduced
King Wealth12,000$416.0K0.07%00.0%Unchanged
Moran Wealth Management, LLC11,780$408.2K0.01%+1,044+9.7%Added
Franklin Street Advisors Inc11,470$397.0K0.03%00.0%Unchanged
ProShare Advisors LLC11,270$390.5K0.00%−3,075−21.4%Reduced
Cerity Partners LLC11,236$389.3K0.00%−690−5.8%Reduced
Allianz Asset Management GmbH11,100$384.6K0.00%00.0%Unchanged
SG Americas Securities, LLC10,951$379.0K0.00%+10,951New
Verition Fund Management LLC10,895$377.5K0.00%+1,713+18.7%Added
Sherbrooke Park Advisers LLC10,805$374.4K0.07%−9,326−46.3%Reduced
Raymond James & Associates10,529$364.8K0.00%−422−3.9%Reduced
CWM Advisors, LLC10,234$354.6K0.04%−2,106−17.1%Reduced
Royal Bank of Canada10,222$354.0K0.00%+4,543+80.0%Added
Principal Financial Group Inc10,028$347.5K0.00%−4,341−30.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)9,844$341.1K0.00%−19−0.2%Reduced
Squarepoint Ops LLC9,823$340.4K0.00%+9,823New
Teacher Retirement System of Texas9,606$333.0K0.00%−664−6.5%Reduced
Brevan Howard Capital Management LP8,971$310.8K0.02%+8,971New
Group One Trading, L.P.8,638$299.3K0.01%−19,725−69.5%Reduced
US Bancorp8,567$296.8K0.00%+2,281+36.3%Added
Man Group plc7,655$265.2K0.00%+7,655New
Graham Capital Management, L.P.7,574$262.4K0.01%−10,638−58.4%Reduced
HSBC Holdings PLC7,529$256.8K0.00%−105,358−93.3%Reduced
Brinker Capital Investments, LLC7,388$256.0K0.00%+7,388New
Orion Portfolio Solutions, LLC7,388$256.0K0.00%+7,388New
Victory Capital Management Inc7,150$247.7K0.00%−58−0.8%Reduced
China Universal Asset Management Co., Ltd.6,891$238.8K0.03%−4,301−38.4%Reduced
Captrust Financial Advisors6,140$212.8K0.00%+6,140New
Lazard Asset Management LLC6,071$210.0K0.00%+3,656+151.4%Added
Ameritas Investment Partners, Inc.5,912$204.9K0.01%00.0%Unchanged
Pictet Asset Management Holding SA5,848$202.6K0.00%+5,848New
Jump Financial, LLC5,783$200.4K0.00%+5,783New
Great West Life Assurance Co5,213$181.0K0.00%−3,870−42.6%Reduced
Point72 (DIFC) Ltd4,415$153.0K0.01%+4,415New
BNP Paribas Arbitrage, SA3,697$128.1K0.00%−43,536−92.2%Reduced
Nisa Investment Advisors, LLC2,745$95.1K0.00%+54+2.0%Added
Amundi2,707$93.4K0.00%00.0%Unchanged
Virtus ETF Advisers LLC2,635$91.3K0.04%−1,540−36.9%Reduced
Quest Partners LLC2,431$84.2K0.01%−3,469−58.8%Reduced
Amalgamated Bank2,023$70.0K0.00%+74+3.8%Added
Mirae Asset Global Investments Co., Ltd.1,751$55.8K0.00%−27,807−94.1%Reduced
State of Wyoming1,491$51.7K0.01%+1,491New
KBC Group NV1,356$47.0K0.00%+154+12.8%Added
Russell Investments Group, Ltd.1,216$42.1K0.00%00.0%Unchanged
Global Retirement Partners, LLC536$18.6K0.00%+236+78.7%Added
Advisor Group Holdings, Inc.470$16.3K0.00%−2,081−81.6%Reduced
Allspring Global Investments Holdings, LLC428$14.8K0.00%−1,542−78.3%Reduced
Pacer Advisors, Inc.428$14.8K0.00%−685−61.5%Reduced
Comerica Bank270$9.37K0.00%00.0%Unchanged
Daiwa Securities Group Inc.215$7.00K0.00%00.0%Unchanged
Hillsdale Investment Management Inc.170$5.89K0.00%−30−15.0%Reduced
CWM, LLC126$4.00K0.00%−49−28.0%Reduced
Clearstead Advisors, LLC110$3.81K0.00%+110New
GAMMA Investing LLC65$2.25K0.00%+17+35.4%Added
Lindbrook Capital, LLC49$1.70K0.00%−124−71.7%Reduced
Farther Finance Advisors, LLC45$1.58K0.00%+5+12.5%Added
Innealta Capital, LLC42$1.46K0.00%+42New
Parallel Advisors, LLC27$9360.00%+27New
Rothschild Investment LLC20$6930.00%+15+300.0%Added
Bell Investment Advisors, Inc17$5900.00%00.0%Unchanged
Institutional & Family Asset Management, LLC16$5540.00%00.0%Unchanged
The PNC Financial Services Group, Inc.14$4850.00%+14New
Smartleaf Asset Management LLC15$4780.00%+15New
Principal Securities, Inc.6$2080.00%00.0%Unchanged
Covestor Ltd8$00.00%+4+100.0%Added
CIBC World Markets Corp0$00.00%−200,000−100.0%Sold out
Walleye Capital LLC0$00.00%−134,114−100.0%Sold out
Privium Fund Management B.V.0$00.00%−114,024−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−100,000−100.0%Sold out
CIBC World Markets Inc.0$00.00%−87,000−100.0%Sold out
Ghost Tree Capital, LLC0$00.00%−75,000−100.0%Sold out
Citadel Advisors LLC0$00.00%−45,616−100.0%Sold out
Resolute Capital Asset Partners LLC0$00.00%−39,500−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−34,500−100.0%Sold out
Twinbeech Capital LP0$00.00%−34,468−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−31,400−100.0%Sold out
American International Group, Inc.0$00.00%−28,149−100.0%Sold out