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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2021

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
139
+12 vs. Q1 2021
Shares held
48.2M
+3.82M (+8.6%) vs. Q1 2021
Total value
$2.16B
+$1.01B (+88.1%) vs. Q1 2021
New holders
27
60 more added
Sold out
15
36 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 139 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2021: $2.16B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2021.

Institutions holding PTGX in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
IFP Advisors, Inc8$00.00%−34−81.0%Reduced
Signaturefd, LLC46$2.00K0.00%00.0%Unchanged
Harbour Investments, Inc.75$3.00K0.00%+2+2.7%Added
Daiwa Securities Group Inc.81$4.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.95$4.00K0.00%+32+50.8%Added
State of Wyoming121$5.00K0.00%+64+112.3%Added
Truvestments Capital LLC250$11.0K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.230$11.0K0.00%+37+19.2%Added
Hartford Financial Management Inc.300$13.0K0.00%00.0%Unchanged
Macquarie Group Ltd307$14.0K0.00%−1,432−82.3%Reduced
US Bancorp355$16.0K0.00%00.0%Unchanged
Lindbrook Capital, LLC450$20.0K0.00%−2,750−85.9%Reduced
Nisa Investment Advisors, LLC450$20.0K0.00%00.0%Unchanged
Penserra Capital Management LLC1,000$44.0K0.00%+30+3.1%Added
Eagle Bay Advisors LLC1,000$45.0K0.04%+1,000New
BNP Paribas Arbitrage, SA1,601$71.9K0.00%−3,037−65.5%Reduced
Great West Life Assurance Co1,982$89.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,046$92.0K0.00%+499+32.3%Added
O'Shaughnessy Asset Management, LLC2,403$108.0K0.00%+197+8.9%Added
UBS Group AG2,671$120.0K0.00%−41,902−94.0%Reduced
FORA Capital, LLC2,731$123.0K0.02%+2,731New
SG Americas Securities, LLC2,810$126.0K0.00%−5,915−67.8%Reduced
Ameritas Investment Partners, Inc.3,241$145.0K0.01%+340+11.7%Added
Royal Bank of Canada3,330$149.0K0.00%+6+0.2%Added
Cubist Systematic Strategies, LLC3,900$175.0K0.00%−10,800−73.5%Reduced
Engineers Gate Manager LP4,710$211.0K0.01%+4,710New
Gotham Asset Management, LLC4,793$215.0K0.01%+4,793New
Schonfeld Strategic Advisors LLC5,000$224.0K0.00%+5,000New
Virtus ETF Advisers LLC5,441$244.0K0.10%−8,905−62.1%Reduced
Winton Group Ltd5,431$244.0K0.01%+5,431New
Voloridge Investment Management, LLC6,504$292.0K0.00%+6,504New
Barclays PLC7,405$333.0K0.00%−30,461−80.4%Reduced
Amalgamated Bank7,807$350.0K0.00%+7,807New
Martingale Asset Management L P8,308$374.0K0.00%+8,308New
STRS Ohio8,800$394.0K0.00%−1,200−12.0%Reduced
Vontobel Holding Ltd.10,000$449.0K0.00%00.0%Unchanged
Birchview Capital, LP10,000$449.0K0.27%00.0%Unchanged
State Board of Administration of Florida Retirement System10,448$469.0K0.00%+1,818+21.1%Added
Arizona State Retirement System10,699$480.0K0.00%+55+0.5%Added
Metropolitan Life Insurance Co11,552$518.5K0.01%+2,268+24.4%Added
Bingham Osborn & Scarborough LLC11,640$522.0K0.04%−4,000−25.6%Reduced
Legal & General Group Plc12,561$563.0K0.00%+2,016+19.1%Added
DekaBank Deutsche Girozentrale14,000$616.0K0.00%00.0%Unchanged
Kestra Advisory Services, LLC13,939$626.0K0.01%+310+2.3%Added
MetLife Investment Management15,088$677.1K0.01%+1,564+11.6%Added
Millennium Management LLC15,440$693.0K0.00%+4,548+41.8%Added
Voya Investment Management LLC16,250$729.0K0.00%+1,156+7.7%Added
Principal Financial Group Inc16,540$743.0K0.00%+8,364+102.3%Added
Invesco Ltd.18,122$814.0K0.00%+8,019+79.4%Added
ProShare Advisors LLC18,621$836.0K0.00%+3,254+21.2%Added
J. Goldman & Co LP19,986$897.0K0.06%−29,593−59.7%Reduced
Monashee Investment Management LLC20,000$898.0K0.11%+20,000New
Franklin Street Advisors Inc20,250$909.0K0.08%−2,000−9.0%Reduced
Susquehanna International Group, LLP21,333$957.0K0.00%−12,801−37.5%Reduced
King Wealth22,000$987.0K0.20%00.0%Unchanged
Manufacturers Life Insurance Company, The23,025$1.03M0.00%+2,986+14.9%Added
American International Group, Inc.23,165$1.04M0.00%+2,638+12.9%Added
HighVista Strategies LLC25,853$1.16M0.82%+25,853New
AQR Capital Management LLC26,608$1.19M0.00%−3,779−12.4%Reduced
Credit Suisse AG27,455$1.23M0.00%+6,215+29.3%Added
UBS Asset Management Americas Inc27,598$1.24M0.00%+2,598+10.4%Added
Nuveen Asset Management, LLC166,325$1.29M0.00%+21,625+14.9%Added
Prudential Financial Inc29,845$1.34M0.00%−3,770−11.2%Reduced
Wells Fargo & Company30,018$1.35M0.00%−8,417−21.9%Reduced
Skandinaviska Enskilda Banken AB (publ)30,628$1.38M0.01%+30,628New
Ensign Peak Advisors, Inc33,230$1.49M0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC34,620$1.55M0.03%−13,000−27.3%Reduced
Gyon Technologies Capital Management, LP35,056$1.57M0.52%+35,056New
New York State Common Retirement Fund35,790$1.61M0.00%+8,290+30.1%Added
Rafferty Asset Management, LLC39,192$1.76M0.01%−36,784−48.4%Reduced
Rhumbline Advisers40,812$1.83M0.00%+7,597+22.9%Added
Alliancebernstein L.P.45,900$2.06M0.00%+15,300+50.0%Added
Russell Investments Group, Ltd.54,004$2.42M0.00%+3,271+6.4%Added
California State Teachers Retirement System57,003$2.56M0.00%+3,880+7.3%Added
State of Wisconsin Investment Board61,600$2.77M0.01%+7,900+14.7%Added
Federated Hermes, Inc.62,015$2.78M0.01%+62,015New
Bank of Montreal64,280$2.84M0.00%−25,793−28.6%Reduced
Bank of America Corp65,733$2.95M0.00%+24,018+57.6%Added
Morgan Stanley69,830$3.13M0.00%+65,107+1,378.5%Added
EAM Global Investors LLC70,185$3.15M0.87%+70,185New
Parametric Portfolio Associates LLC71,400$3.20M0.00%+31,201+77.6%Added
Kennedy Capital Management, Inc.71,947$3.23M0.07%−3,571−4.7%Reduced
Citigroup Inc72,540$3.26M0.00%−23,180−24.2%Reduced
Two Sigma Investments, LP73,377$3.29M0.01%−10,139−12.1%Reduced
Allianz Asset Management GmbH74,260$3.33M0.00%00.0%Unchanged
TD Asset Management Inc68,842$3.40M0.00%+7,371+12.0%Added
Emerald Mutual Fund Advisers Trust76,965$3.45M0.11%+76,965New
Candriam Luxembourg S.C.A.83,646$3.75M0.03%+83,646New
Swiss National Bank86,800$3.90M0.00%+3,200+3.8%Added
Iszo Capital Management LP93,883$4.21M1.53%+93,883New
EAM Investors, LLC101,019$4.53M0.70%+101,019New
Emerald Advisers, LLC103,850$4.66M0.17%+103,850New
SEI Investments Co106,534$4.78M0.01%+19,654+22.6%Added
Polar Capital Holdings Plc119,203$5.35M0.03%+119,203New
Silvercrest Asset Management Group LLC119,391$5.36M0.04%+119,391New
Parkman Healthcare Partners LLC130,000$5.83M1.28%+130,000New
Panagora Asset Management Inc137,198$6.16M0.03%−92,315−40.2%Reduced
Lord, Abbett & Co. LLC138,608$6.22M0.01%+138,608New
Affinity Asset Advisors, LLC140,100$6.29M3.00%+90,100+180.2%Added
Twin Lakes Capital Management, LLC143,440$6.44M3.58%+556+0.4%Added