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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
346
+27 vs. Q1 2026
Shares held
75.9M
−104.9K (−0.1%) vs. Q1 2026
Total value
$9.30B
+$1.30B (+16.2%) vs. Q1 2026
New holders
62
141 more added
Sold out
35
90 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 346 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2026: $9.30B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.

Institutions holding PTGX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Evolution Advisers, Inc.5$00.00%+5New
Walleye Capital LLC1$1230.00%+1New
Abound Wealth Management2$2460.00%00.0%Unchanged
Stone House Investment Management, LLC3$3680.00%+3New
Davis Capital Management3$3680.00%+3New
Kilter Group LLC4$4910.00%00.0%Unchanged
SJS Investment Consulting Inc.4$4910.00%+4New
DecisionPoint Financial, LLC4$5010.00%00.0%Unchanged
Rialto Wealth Management, LLC5$6130.00%+5New
Ares Financial Consulting, LLC6$7350.00%+6New
Trust Co7$8580.00%00.0%Unchanged
Hughes Financial Services, LLC8$9810.00%+2+33.3%Added
Noble Wealth Management PBC8$9810.00%+8New
Rossby Financial, LCC9$1.10K0.00%00.0%Unchanged
Action Point Financial Planning, LLC10$1.10K0.00%+10New
Gilpin Wealth Management, LLC9$1.10K0.00%00.0%Unchanged
JFS Wealth Advisors, LLC9$1.10K0.00%+9New
Prestige Wealth Management Group LLC10$1.23K0.00%+7+233.3%Added
Ameriflex Group, Inc.11$1.35K0.00%+11New
Ankerstar Wealth, LLC12$1.47K0.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC15$1.84K0.00%+15New
Private Wealth Management Group, LLC16$1.96K0.00%00.0%Unchanged
Triumph Capital Management18$2.21K0.00%00.0%Unchanged
UMA Financial Services, Inc.19$2.33K0.00%−2−9.5%Reduced
Whipplewood Advisors, LLC22$2.70K0.00%00.0%Unchanged
Versant Capital Management, Inc27$3.31K0.00%00.0%Unchanged
Marquette Asset Management, LLC28$3.43K0.00%00.0%Unchanged
Torren Management, LLC30$3.68K0.00%00.0%Unchanged
Huntington National Bank35$4.29K0.00%00.0%Unchanged
Farmers & Merchants Investments Inc35$4.29K0.00%00.0%Unchanged
Wolff Wiese Magana LLC35$4.29K0.00%00.0%Unchanged
Harbour Investments, Inc.36$4.41K0.00%+17+89.5%Added
Zions Bancorporation, National Association36$4.41K0.00%+13+56.5%Added
Hollencrest Capital Management45$5.52K0.00%00.0%Unchanged
Fulcrum Asset Management LLP46$5.59K0.00%+46New
Raffa Wealth Management, LLC60$7.36K0.00%00.0%Unchanged
Parkside Financial Bank & Trust76$9.32K0.00%00.0%Unchanged
Sankala Group LLC60$9.47K0.01%00.0%Unchanged
SBI Securities Co., Ltd.80$9.81K0.00%+10+14.3%Added
Brown Brothers Harriman & Co81$9.93K0.00%00.0%Unchanged
SMA Capital LLC84$10.3K0.00%+84New
Bell Investment Advisors, Inc86$10.5K0.00%+5+6.2%Added
SRS Capital Advisors, Inc.95$11.6K0.00%+95New
Rothschild Investment LLC106$13.0K0.00%−1−0.9%Reduced
WPG Advisers, LLC107$13.1K0.01%+10+10.3%Added
Cedar Mountain Advisors, LLC113$13.9K0.00%00.0%Unchanged
Parallel Advisors, LLC118$14.5K0.00%−5−4.1%Reduced
Massmutual Trust Co FSB131$16.1K0.00%+6+4.8%Added
Accent Capital Management, LLC138$16.9K0.01%+138New
Silver Grove Financial Group, Inc.149$18.3K0.01%+149New
Bare Financial Services, Inc186$22.8K0.01%+91+95.8%Added
Clearstead Advisors, LLC200$24.5K0.00%00.0%Unchanged
E Fund Management (Hong Kong) Co., Ltd.211$25.9K0.01%+55+35.3%Added
Sterling Capital Management LLC216$26.5K0.00%−161−42.7%Reduced
Keating Financial Advisory Services, Inc.242$29.7K0.00%+18+8.0%Added
Allworth Financial LP254$31.1K0.00%−59−18.8%Reduced
Graticule Asia Macro Advisors LLC260$31.9K0.00%+260New
Signaturefd, LLC322$39.5K0.00%+34+11.8%Added
Quent Capital, LLC337$41.3K0.00%+337New
Quantbot Technologies LP342$41.9K0.00%+342New
Umb Bank N A373$45.7K0.00%+20+5.7%Added
Pacer Advisors, Inc.436$53.0K0.00%−4,480−91.1%Reduced
Optiver Holding B.V.436$53.4K0.00%+436New
Farther Finance Advisors, LLC442$54.2K0.00%+109+32.7%Added
EverSource Wealth Advisors, LLC514$63.0K0.00%−397−43.6%Reduced
Kemnay Advisory Services Inc.574$70.4K0.01%+53+10.2%Added
Salomon & Ludwin, LLC595$74.5K0.01%00.0%Unchanged
Harbor Investment Advisory, LLC724$88.7K0.01%+724New
Smartleaf Asset Management LLC890$108.3K0.00%00.0%Unchanged
Larson Financial Group LLC976$119.6K0.00%+157+19.2%Added
Canton Hathaway, LLC1,000$122.6K0.02%00.0%Unchanged
Hantz Financial Services, Inc.1,007$123.0K0.00%+150+17.5%Added
Global Retirement Partners, LLC1,055$129.3K0.00%+1,055New
Truvestments Capital LLC1,156$141.7K0.02%−5−0.4%Reduced
GF Fund Management Co. Ltd.1,353$165.9K0.00%−51−3.6%Reduced
Axxion S.A.1,500$183.9K0.01%+1,500New
Covestor Ltd1,528$188.0K0.11%+653+74.6%Added
KBC Group NV1,574$193.0K0.00%00.0%Unchanged
Shelton Capital Management1,636$200.5K0.00%−272−14.3%Reduced
CFC Planning Co LLC1,675$205.3K0.12%+1,675New
Connecticut Capital Management Group, LLC1,736$212.8K0.17%+1,736New
Advisor Group Holdings, Inc.1,776$217.7K0.00%+579+48.4%Added
Stephens Inc1,807$221.5K0.00%+1,807New
MML Investors Services, LLC1,824$223.6K0.00%+1,824New
Oppenheimer & Co Inc1,900$232.9K0.00%00.0%Unchanged
Everence Capital Management Inc1,924$236.0K0.01%+1,924New
Concurrent Investment Advisors, LLC1,926$236.1K0.00%−134−6.5%Reduced
CIBC Asset Management Inc1,973$241.8K0.00%−694−26.0%Reduced
Axiom Investment Management LLC2,000$245.2K0.16%00.0%Unchanged
Axq Capital, LP2,138$262.1K0.03%+2,138New
DnB Asset Management AS2,244$275.1K0.00%00.0%Unchanged
Empowered Funds, LLC2,264$277.5K0.00%−57−2.5%Reduced
RSM US Wealth Management LLC2,317$284.0K0.00%+83+3.7%Added
Mount Yale Investment Advisors, LLC2,369$290.4K0.01%+2,369New
Palumbo Wealth Management LLC2,390$293.0K0.06%−3,693−60.7%Reduced
Nykredit A/S2,415$296.0K0.00%+2,415New
Tower Research Capital LLC (TRC)2,539$311.2K0.01%−2,422−48.8%Reduced
NBC Securities, Inc.2,545$312.0K0.02%−2−0.1%Reduced
Blueshift Asset Management, LLC2,564$314.3K0.07%+2,564New
New Age Alpha Advisors, LLC2,612$320.2K0.01%−94−3.5%Reduced