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Catalio Capital Management, LP

SEC CIK
0001958125
Latest filing
Aug 14, 2026

The latest 13F from Catalio Capital Management, LP covers Q2 2026 (filed Aug 14, 2026): 39 long positions worth $532.1M. The top 10 holdings make up 56.7% of the portfolio, and the largest is Avalyn Pharma Inc. (AVLN) at 10.4%. Livermore has 8 filings on Form 13F from this institution, going back to Q4 2024.

What changed in Q2 2026

Share counts compared with Q1 2026: how many positions were new, added to, reduced or sold out, and the biggest buys and sells. Dollar amounts are estimated at the quarter-end prices implied by the filing.

Full comparison
New
10
Est. +$171.7M
Added
15
Est. +$51.8M
Reduced
9
Est. −$136.6M
Sold out
12
Est. −$117.0M

Top 5 holdings

Share of this quarter's portfolio value

  1. AVLNAvalyn Pharma Inc.
    10.4%$55.2MHistory
  2. JNJJohnson & Johnson
    6.6%$35.3MHistory
  3. GILDGilead Sciences, Inc.
    6.4%$34.0MHistory
  4. BBIOBridgeBio Pharma, Inc.
    6.4%$33.9MHistory
  5. SNDXSyndax Pharmaceuticals Inc
    5.0%$26.6MHistory

Share of portfolio

Top 5 holdings and the other 34 positions, by share of portfolio value

  1. AVLN10.4%
  2. JNJ6.6%
  3. GILD6.4%
  4. BBIO6.4%
  5. SNDX5.0%
  6. Other 34 positions65.2%

Biggest buys

New and added positions, by estimated amount bought

  1. AVLNAvalyn Pharma Inc.
    +$55.2MNewHistory
  2. JNJJohnson & Johnson
    +$35.3MNewHistory
  3. PBLSParabilis Medicines, Inc.
    +$22.6MNewHistory
  4. GILDGilead Sciences, Inc.
    +$13.3MAddedHistory
  5. PTGXProtagonist Therapeutics, Inc
    +$13.1MNewHistory

Largest weight increases

New and added positions, by percentage points of the portfolio gained

  1. AVLNAvalyn Pharma Inc.
    +10.37 pp0.0% → 10.4%History
  2. JNJJohnson & Johnson
    +6.63 pp0.0% → 6.6%History
  3. PBLSParabilis Medicines, Inc.
    +4.24 pp0.0% → 4.2%History
  4. PTGXProtagonist Therapeutics, Inc
    +2.46 pp0.0% → 2.5%History
  5. AXSMAxsome Therapeutics, Inc.
    +1.99 pp0.0% → 2.0%History

Biggest sells

Reduced and sold-out positions, by estimated amount sold

  1. DNTHDianthus Therapeutics, Inc.
    −$51.4MReducedHistory
  2. ASNDAscendis Pharma A/S
    −$26.0MReducedHistory
  3. DFTXDefinium Therapeutics, Inc.
    −$22.4MReducedHistory
  4. TERNTerns Pharmaceuticals, Inc.
    −$21.6MSold outHistory
  5. SLNOSoleno Therapeutics Inc
    −$19.3MSold outHistory

Largest weight decreases

Reduced and sold-out positions, by percentage points of the portfolio lost

  1. DNTHDianthus Therapeutics, Inc.
    −9.22 pp9.8% → 0.6%History
  2. ASNDAscendis Pharma A/S
    −4.58 pp6.2% → 1.6%History
  3. TERNTerns Pharmaceuticals, Inc.
    −4.50 pp4.5% → 0.0%History
  4. SLNOSoleno Therapeutics Inc
    −4.04 pp4.0% → 0.0%History
  5. BSXBoston Scientific Corp
    −3.92 pp3.9% → 0.0%History

Metrics

13F metrics for Q2 2026, computed only from the numbers in the filings. Definitions below.

Portfolio value
$532.1M
+$53.4M (+11.2%) vs. prior quarter
Positions
39
−2 vs. prior quarter
Top 10 concentration
56.7%
Top 10 as share of value
Turnover
44.2%
Q2 2026, one quarter
Average holding period
3.2 quarters
Weighted by value

How these are calculated

  • Portfolio value: the market value of all long positions in the 13F, as reported at quarter end, excluding options.
  • Top 10 concentration: the combined value of the 10 largest positions as a share of portfolio value.
  • Turnover: the smaller of this quarter's estimated purchases and estimated sales, divided by the average of this and last quarter's portfolio value. Estimates multiply the change in shares by the quarter-end price implied by the filing (market value divided by shares); new positions use this quarter's value and sold-out positions last quarter's. Only positions reported in shares count, and it is not calculated when the previous quarter was not filed.
  • Average holding period: how many consecutive quarters each current position has been held (including this one; a quarter without the position or without a filing starts the count over), weighted by this quarter's value. Counting starts with the first 13F in Livermore (Q4 2024), so positions held before then are understated.

13F filings by quarter

7 quarters, going back to Q4 2024. Bars show each quarter's 13F portfolio value; quarters without a filing are left blank.

Peak $565.8M (Q4 2025)

Q4 2024: $457.1MQ1 2025: $403.4MQ2 2025: $476.9MQ3 2025: $540.9MQ4 2025: $565.8MQ1 2026: $478.7MQ2 2026: $532.1M
Q4 2024Q2 2026
13F filings of Catalio Capital Management, LP by quarter
QuarterFiledPositionsValueTop 3 holdingsChangesFiling
Q2 2026Aug 14, 202639$532.1MAVLNJNJGILDvs. Q1 2026SEC
Q1 2026May 15, 202641$478.7MDNTHBBIOASNDvs. Q4 2025SEC
Q4 2025Sep 2, 2026Amended45$565.8MGILDBMYBSXvs. Q3 2025SEC
Q3 2025Nov 14, 202538$540.9MLLYABBVBBIOvs. Q2 2025SEC
Q2 2025Aug 14, 202540$476.9MLLYBBIOSLNOvs. Q1 2025SEC
Q1 2025May 15, 202535$403.4MBDXSWTXBBIOvs. Q4 2024SEC
Q4 2024Feb 14, 202533$457.1MBDXASNDBMY–SEC