Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −104.9K (−0.1%) vs. Q1 2026
- Total value
- $9.30B
- +$1.30B (+16.2%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caption Management, LLC | 45,000 | $5.52M | 0.19% | +45,000 | New |
| Arrowstreet Capital, Limited Partnership | 44,529 | $5.46M | 0.00% | +44,529 | New |
| OrbiMed Advisors LLC | 42,100 | $5.16M | 0.10% | 00.0% | Unchanged |
| EFG International AG | 40,501 | $4.96M | 0.09% | −9,585−19.1% | Reduced |
| Thrivent Financial for Lutherans | 39,697 | $4.87M | 0.01% | +472+1.2% | Added |
| Elmind Capital, LP | 38,000 | $4.66M | 1.17% | 00.0% | Unchanged |
| LMR Partners LLP | 38,000 | $4.66M | 0.03% | +7,150+23.2% | Added |
| Mutual of America Capital Management LLC | 36,252 | $4.44M | 0.04% | +29,527+439.1% | Added |
| MetLife Investment Management | 35,792 | $4.39M | 0.02% | +3,993+12.6% | Added |
| Birchview Capital, LP | 35,018 | $4.29M | 2.01% | +18+0.1% | Added |
| State of Wisconsin Investment Board | 33,152 | $4.06M | 0.01% | +2,385+7.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 31,377 | $3.84M | 0.00% | +773+2.5% | Added |
| Illinois Municipal Retirement Fund | 29,211 | $3.58M | 0.04% | +615+2.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 29,161 | $3.57M | 0.01% | +1,901+7.0% | Added |
| Vanguard Global Advisers, LLC | 28,463 | $3.49M | 0.00% | +3,798+15.4% | Added |
| Pathstone Holdings, LLC | 28,187 | $3.46M | 0.01% | −65−0.2% | Reduced |
| State of Alaska, Department of Revenue | 28,084 | $3.44M | 0.03% | −9,063−24.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 28,072 | $3.44M | 0.02% | +28,072 | New |
| EAM Investors, LLC | 27,491 | $3.37M | 0.30% | −423−1.5% | Reduced |
| Teachers Retirement System of the State of Kentucky | 26,528 | $3.25M | 0.02% | 00.0% | Unchanged |
| Louisiana State Employees Retirement System | 26,500 | $3.25M | 0.05% | +400+1.5% | Added |
| Rafferty Asset Management, LLC | 26,099 | $3.20M | 0.01% | −20,653−44.2% | Reduced |
| HSBC Holdings PLC | 25,952 | $3.20M | 0.00% | +24,045+1,260.9% | Added |
| Natixis Advisors, L.P. | 25,459 | $3.12M | 0.00% | +2,821+12.5% | Added |
| Brevan Howard Capital Management LP | 25,270 | $3.10M | 0.04% | +25,270 | New |
| New York State Common Retirement Fund | 25,243 | $3.09M | 0.00% | +6,861+37.3% | Added |
| Allspring Global Investments Holdings, LLC | 24,054 | $3.01M | 0.00% | −5,862−19.6% | Reduced |
| HighVista Strategies LLC | 24,460 | $3.00M | 0.68% | −9,392−27.7% | Reduced |
| Exchange Traded Concepts, LLC | 24,124 | $2.96M | 0.01% | +351+1.5% | Added |
| Intech Investment Management LLC | 24,056 | $2.95M | 0.03% | +11,050+85.0% | Added |
| Artia Global Partners LP | 22,951 | $2.81M | 0.53% | +20+0.1% | Added |
| State of Tennessee, Treasury Department | 22,771 | $2.79M | 0.01% | −526−2.3% | Reduced |
| Polen Capital Management LLC | 22,651 | $2.78M | 0.02% | −1,686−6.9% | Reduced |
| Guggenheim Capital LLC | 21,800 | $2.67M | 0.02% | +6,520+42.7% | Added |
| Handelsbanken Fonder AB | 21,400 | $2.62M | 0.01% | +1,500+7.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,934 | $2.57M | 0.00% | +7,522+56.1% | Added |
| Erste Asset Management GmbH | 21,000 | $2.55M | 0.02% | +7,500+55.6% | Added |
| Envestnet Asset Management Inc | 19,134 | $2.35M | 0.00% | +2,817+17.3% | Added |
| SG Americas Securities, LLC | 19,080 | $2.34M | 0.00% | +983+5.4% | Added |
| Gotham Asset Management, LLC | 18,663 | $2.29M | 0.01% | −2,492−11.8% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 18,155 | $2.23M | 0.02% | +2,321+14.7% | Added |
| Jane Street Group, LLC | 16,882 | $2.07M | 0.00% | +13,275+368.0% | Added |
| State of New Jersey Common Pension Fund D | 16,506 | $2.02M | 0.01% | −586−3.4% | Reduced |
| Yousif Capital Management, LLC | 16,483 | $2.02M | 0.02% | +251+1.5% | Added |
| Phocas Financial Corp. | 16,378 | $2.01M | 0.28% | +16,378 | New |
| StemPoint Capital LP | 16,303 | $2.00M | 0.35% | −56,274−77.5% | Reduced |
| State Board of Administration of Florida Retirement System | 16,303 | $2.00M | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 16,268 | $1.99M | 0.01% | −584−3.5% | Reduced |
| Profund Advisors LLC | 16,118 | $1.98M | 0.05% | −6,749−29.5% | Reduced |
| Bamco Inc | 16,000 | $1.96M | 0.00% | +1,000+6.7% | Added |
| STRS Ohio | 15,100 | $1.85M | 0.01% | −300−1.9% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 14,335 | $1.76M | 0.01% | −197−1.4% | Reduced |
| Weiss Asset Management LP | 14,209 | $1.74M | 0.02% | +4,429+45.3% | Added |
| Arizona State Retirement System | 14,085 | $1.73M | 0.01% | +347+2.5% | Added |
| Oregon Public Employees Retirement Fund | 13,694 | $1.68M | 0.02% | +238+1.8% | Added |
| Glenmede Trust Co NA | 13,387 | $1.64M | 0.01% | +4,152+45.0% | Added |
| Fifth Third Bancorp | 13,112 | $1.61M | 0.00% | −90−0.7% | Reduced |
| AQR Capital Management LLC | 13,096 | $1.61M | 0.00% | +1,222+10.3% | Added |
| Jackson Creek Investment Advisors LLC | 11,610 | $1.59M | 0.53% | +11,610 | New |
| Franklin Street Advisors Inc | 12,810 | $1.57M | 0.09% | +1,725+15.6% | Added |
| Vanguard Investments Australia, Ltd. | 12,655 | $1.55M | 0.00% | +525+4.3% | Added |
| Bleakley Financial Group, LLC | 12,538 | $1.54M | 0.02% | −264−2.1% | Reduced |
| Aquatic Capital Management LLC | 12,180 | $1.49M | 0.05% | +12,180 | New |
| Calamos Advisors LLC | 11,931 | $1.46M | 0.01% | −11,542−49.2% | Reduced |
| Colony Group, LLC | 11,878 | $1.46M | 0.00% | +11,878 | New |
| Barclays PLC | 11,810 | $1.45M | 0.00% | −2,595−18.0% | Reduced |
| KLP Kapitalforvaltning AS | 11,600 | $1.42M | 0.00% | +600+5.5% | Added |
| China Universal Asset Management Co., Ltd. | 11,485 | $1.41M | 0.08% | −3,438−23.0% | Reduced |
| Virginia Retirement Systems Et Al | 11,200 | $1.37M | 0.01% | −1,800−13.8% | Reduced |
| Winton Group Ltd | 10,884 | $1.33M | 0.04% | −1,789−14.1% | Reduced |
| ProShare Advisors LLC | 10,878 | $1.33M | 0.00% | −1,040−8.7% | Reduced |
| Virtus Investment Advisers, Inc. | 10,593 | $1.30M | 0.30% | +7,733+270.4% | Added |
| Cache Advisors, LLC | 10,143 | $1.24M | 0.11% | 00.0% | Unchanged |
| Verition Fund Management LLC | 10,143 | $1.24M | 0.01% | +10,143 | New |
| Allianz Asset Management GmbH | 9,600 | $1.18M | 0.00% | 00.0% | Unchanged |
| J. Goldman & Co LP | 9,414 | $1.15M | 0.04% | −300−3.1% | Reduced |
| Bridgewater Associates, LP | 9,269 | $1.14M | 0.00% | +3,993+75.7% | Added |
| AlphaCentric Advisors LLC | 9,171 | $1.12M | 0.95% | +131+1.4% | Added |
| Maryland State Retirement & Pension System | 8,792 | $1.08M | 0.02% | +225+2.6% | Added |
| Holocene Advisors, LP | 8,495 | $1.04M | 0.00% | −201,421−96.0% | Reduced |
| Quantinno Capital Management LP | 8,176 | $1.00M | 0.00% | +1,739+27.0% | Added |
| Virtu Financial LLC | 8,163 | $1.00M | 0.03% | +8,163 | New |
| Cambria Investment Management, L.P. | 7,869 | $964.6K | 0.05% | +1,004+14.6% | Added |
| Natixis | 7,776 | $953.2K | 0.00% | +7,776 | New |
| Amundi | 7,692 | $942.9K | 0.00% | +3,579+87.0% | Added |
| Fred Alger Management, LLC | 7,650 | $937.7K | 0.00% | +7,650 | New |
| Cerity Partners LLC | 6,563 | $804.5K | 0.00% | +870+15.3% | Added |
| Captrust Financial Advisors | 6,522 | $799.5K | 0.00% | +4,620+242.9% | Added |
| Brinker Capital Investments, LLC | 6,428 | $787.9K | 0.01% | +21+0.3% | Added |
| Campbell & CO Investment Adviser LLC | 6,206 | $760.7K | 0.04% | +6,206 | New |
| Bank of Montreal | 6,147 | $753.5K | 0.00% | +390+6.8% | Added |
| Xponance, Inc. | 6,062 | $743.1K | 0.00% | +590+10.8% | Added |
| Public Employees Retirement Association of Colorado | 6,001 | $736.0K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 5,978 | $732.8K | 0.01% | +306+5.4% | Added |
| Teacher Retirement System of Texas | 5,967 | $731.4K | 0.00% | −481−7.5% | Reduced |
| Panagora Asset Management Inc | 5,832 | $714.9K | 0.00% | −110,777−95.0% | Reduced |
| CWM Advisors, LLC | 5,591 | $685.4K | 0.03% | +555+11.0% | Added |
| Ameritas Investment Partners, Inc. | 5,586 | $684.7K | 0.02% | +861+18.2% | Added |
| HighTower Advisors, LLC | 5,308 | $650.7K | 0.00% | −78−1.4% | Reduced |
| TFB Advisors LLC | 5,235 | $641.7K | 0.28% | +3,044+138.9% | Added |