Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −104.9K (−0.1%) vs. Q1 2026
- Total value
- $9.30B
- +$1.30B (+16.2%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Quadrature Capital Ltd | 5,222 | $640.1K | 0.01% | +5,222 | New |
| CIBC Bancorp USA Inc. | 5,180 | $635.0K | 0.00% | +2,212+74.5% | Added |
| Kestra Advisory Services, LLC | 5,061 | $620.4K | 0.00% | +7+0.1% | Added |
| Keybank National Association | 4,997 | $612.5K | 0.00% | +711+16.6% | Added |
| Toroso Investments, LLC | 4,988 | $611.4K | 0.00% | −6,046−54.8% | Reduced |
| Jones Financial Companies LLLP | 4,934 | $601.4K | 0.00% | +2,011+68.8% | Added |
| Rockefeller Capital Management L.P. | 4,818 | $590.6K | 0.00% | −10−0.2% | Reduced |
| Mariner, LLC | 4,738 | $580.8K | 0.00% | +1,963+70.7% | Added |
| Los Angeles Capital Management LLC | 4,727 | $579.4K | 0.00% | 00.0% | Unchanged |
| O'Shaughnessy Asset Management, LLC | 4,488 | $550.1K | 0.00% | +2,048+83.9% | Added |
| The PNC Financial Services Group, Inc. | 4,458 | $546.5K | 0.00% | +460+11.5% | Added |
| Engineers Gate Manager LP | 4,373 | $536.0K | 0.01% | +4,373 | New |
| Abel Hall, LLC | 4,286 | $525.4K | 0.09% | +28+0.7% | Added |
| Wealth Enhancement Advisory Services, LLC | 3,958 | $520.2K | 0.00% | +301+8.2% | Added |
| Nisa Investment Advisors, LLC | 4,191 | $513.7K | 0.00% | +389+10.2% | Added |
| King Wealth | 4,000 | $490.0K | 0.05% | 00.0% | Unchanged |
| M&T Bank Corp | 3,984 | $488.4K | 0.00% | +126+3.3% | Added |
| LPL Financial LLC | 3,946 | $483.7K | 0.00% | +1,153+41.3% | Added |
| E Fund Management Co., Ltd. | 3,891 | $477.0K | 0.01% | −2,142−35.5% | Reduced |
| XTX Topco Ltd | 3,868 | $474.1K | 0.01% | +3,868 | New |
| Himension Fund | 3,844 | $471.2K | 0.03% | +3,844 | New |
| Ensign Peak Advisors, Inc | 3,786 | $464.1K | 0.00% | −700−15.6% | Reduced |
| Vestcor Inc | 3,765 | $462.0K | 0.01% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 3,712 | $455.0K | 0.01% | +3,712 | New |
| Velan Capital Investment Management LP | 3,700 | $453.5K | 0.28% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 3,598 | $441.0K | 0.00% | −97,701−96.4% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 3,541 | $434.1K | 0.00% | +3,541 | New |
| US Bancorp | 3,494 | $428.3K | 0.00% | −420−10.7% | Reduced |
| Royal Bank of Canada | 3,473 | $426.0K | 0.00% | +1,874+117.2% | Added |
| Swiss Life Asset Management Ltd | 3,403 | $417.1K | 0.00% | +299+9.6% | Added |
| Crossmark Global Holdings, Inc. | 3,389 | $415.4K | 0.01% | −100−2.9% | Reduced |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 3,298 | $404.3K | 0.12% | −6,036−64.7% | Reduced |
| Eventide Asset Management, LLC | 3,287 | $399.8K | 0.01% | +492+17.6% | Added |
| Burney Co | 3,179 | $389.7K | 0.01% | 00.0% | Unchanged |
| Simplex Trading, LLC | 3,149 | $386.0K | 0.01% | +3,149 | New |
| Pinnacle Wealth Planning Services, Inc. | 3,129 | $383.6K | 0.04% | −3−0.1% | Reduced |
| GAMMA Investing LLC | 3,109 | $381.1K | 0.01% | +208+7.2% | Added |
| State of Wyoming | 3,102 | $380.2K | 0.04% | +3,102 | New |
| PSP Research LLC | 3,000 | $367.7K | 0.20% | 00.0% | Unchanged |
| Triglav Skladi, D.O.O. | 3,000 | $367.7K | 0.02% | +3,000 | New |
| Gabelli Funds LLC | 2,900 | $355.5K | 0.00% | −329−10.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,876 | $352.5K | 0.00% | −452−13.6% | Reduced |
| AE Wealth Management LLC | 2,875 | $352.4K | 0.00% | −13−0.5% | Reduced |
| Norden Group LLC | 2,868 | $351.6K | 0.03% | +58+2.1% | Added |
| Evergreen Capital Management LLC | 2,830 | $346.9K | 0.01% | +10+0.4% | Added |
| Bayforest Capital Ltd | 2,675 | $327.9K | 0.30% | +2,675 | New |
| New Age Alpha Advisors, LLC | 2,612 | $320.2K | 0.01% | −94−3.5% | Reduced |
| Blueshift Asset Management, LLC | 2,564 | $314.3K | 0.07% | +2,564 | New |
| NBC Securities, Inc. | 2,545 | $312.0K | 0.02% | −2−0.1% | Reduced |
| Tower Research Capital LLC (TRC) | 2,539 | $311.2K | 0.01% | −2,422−48.8% | Reduced |
| Nykredit A/S | 2,415 | $296.0K | 0.00% | +2,415 | New |
| Palumbo Wealth Management LLC | 2,390 | $293.0K | 0.06% | −3,693−60.7% | Reduced |
| Mount Yale Investment Advisors, LLC | 2,369 | $290.4K | 0.01% | +2,369 | New |
| RSM US Wealth Management LLC | 2,317 | $284.0K | 0.00% | +83+3.7% | Added |
| Empowered Funds, LLC | 2,264 | $277.5K | 0.00% | −57−2.5% | Reduced |
| DnB Asset Management AS | 2,244 | $275.1K | 0.00% | 00.0% | Unchanged |
| Axq Capital, LP | 2,138 | $262.1K | 0.03% | +2,138 | New |
| Axiom Investment Management LLC | 2,000 | $245.2K | 0.16% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 1,973 | $241.8K | 0.00% | −694−26.0% | Reduced |
| Concurrent Investment Advisors, LLC | 1,926 | $236.1K | 0.00% | −134−6.5% | Reduced |
| Everence Capital Management Inc | 1,924 | $236.0K | 0.01% | +1,924 | New |
| Oppenheimer & Co Inc | 1,900 | $232.9K | 0.00% | 00.0% | Unchanged |
| MML Investors Services, LLC | 1,824 | $223.6K | 0.00% | +1,824 | New |
| Stephens Inc | 1,807 | $221.5K | 0.00% | +1,807 | New |
| Advisor Group Holdings, Inc. | 1,776 | $217.7K | 0.00% | +579+48.4% | Added |
| Connecticut Capital Management Group, LLC | 1,736 | $212.8K | 0.17% | +1,736 | New |
| CFC Planning Co LLC | 1,675 | $205.3K | 0.12% | +1,675 | New |
| Shelton Capital Management | 1,636 | $200.5K | 0.00% | −272−14.3% | Reduced |
| KBC Group NV | 1,574 | $193.0K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 1,528 | $188.0K | 0.11% | +653+74.6% | Added |
| Axxion S.A. | 1,500 | $183.9K | 0.01% | +1,500 | New |
| GF Fund Management Co. Ltd. | 1,353 | $165.9K | 0.00% | −51−3.6% | Reduced |
| Truvestments Capital LLC | 1,156 | $141.7K | 0.02% | −5−0.4% | Reduced |
| Global Retirement Partners, LLC | 1,055 | $129.3K | 0.00% | +1,055 | New |
| Hantz Financial Services, Inc. | 1,007 | $123.0K | 0.00% | +150+17.5% | Added |
| Canton Hathaway, LLC | 1,000 | $122.6K | 0.02% | 00.0% | Unchanged |
| Larson Financial Group LLC | 976 | $119.6K | 0.00% | +157+19.2% | Added |
| Smartleaf Asset Management LLC | 890 | $108.3K | 0.00% | 00.0% | Unchanged |
| Harbor Investment Advisory, LLC | 724 | $88.7K | 0.01% | +724 | New |
| Salomon & Ludwin, LLC | 595 | $74.5K | 0.01% | 00.0% | Unchanged |
| Kemnay Advisory Services Inc. | 574 | $70.4K | 0.01% | +53+10.2% | Added |
| EverSource Wealth Advisors, LLC | 514 | $63.0K | 0.00% | −397−43.6% | Reduced |
| Farther Finance Advisors, LLC | 442 | $54.2K | 0.00% | +109+32.7% | Added |
| Optiver Holding B.V. | 436 | $53.4K | 0.00% | +436 | New |
| Pacer Advisors, Inc. | 436 | $53.0K | 0.00% | −4,480−91.1% | Reduced |
| Umb Bank N A | 373 | $45.7K | 0.00% | +20+5.7% | Added |
| Quantbot Technologies LP | 342 | $41.9K | 0.00% | +342 | New |
| Quent Capital, LLC | 337 | $41.3K | 0.00% | +337 | New |
| Signaturefd, LLC | 322 | $39.5K | 0.00% | +34+11.8% | Added |
| Graticule Asia Macro Advisors LLC | 260 | $31.9K | 0.00% | +260 | New |
| Allworth Financial LP | 254 | $31.1K | 0.00% | −59−18.8% | Reduced |
| Keating Financial Advisory Services, Inc. | 242 | $29.7K | 0.00% | +18+8.0% | Added |
| Sterling Capital Management LLC | 216 | $26.5K | 0.00% | −161−42.7% | Reduced |
| E Fund Management (Hong Kong) Co., Ltd. | 211 | $25.9K | 0.01% | +55+35.3% | Added |
| Clearstead Advisors, LLC | 200 | $24.5K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 186 | $22.8K | 0.01% | +91+95.8% | Added |
| Silver Grove Financial Group, Inc. | 149 | $18.3K | 0.01% | +149 | New |
| Accent Capital Management, LLC | 138 | $16.9K | 0.01% | +138 | New |
| Massmutual Trust Co FSB | 131 | $16.1K | 0.00% | +6+4.8% | Added |
| Parallel Advisors, LLC | 118 | $14.5K | 0.00% | −5−4.1% | Reduced |