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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
346
+27 vs. Q1 2026
Shares held
75.9M
−104.9K (−0.1%) vs. Q1 2026
Total value
$9.30B
+$1.30B (+16.2%) vs. Q1 2026
New holders
62
141 more added
Sold out
35
90 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 346 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2026: $9.30B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.

Institutions holding PTGX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Cedar Mountain Advisors, LLC113$13.9K0.00%00.0%Unchanged
WPG Advisers, LLC107$13.1K0.01%+10+10.3%Added
Rothschild Investment LLC106$13.0K0.00%−1−0.9%Reduced
SRS Capital Advisors, Inc.95$11.6K0.00%+95New
Bell Investment Advisors, Inc86$10.5K0.00%+5+6.2%Added
SMA Capital LLC84$10.3K0.00%+84New
Brown Brothers Harriman & Co81$9.93K0.00%00.0%Unchanged
SBI Securities Co., Ltd.80$9.81K0.00%+10+14.3%Added
Sankala Group LLC60$9.47K0.01%00.0%Unchanged
Parkside Financial Bank & Trust76$9.32K0.00%00.0%Unchanged
Raffa Wealth Management, LLC60$7.36K0.00%00.0%Unchanged
Fulcrum Asset Management LLP46$5.59K0.00%+46New
Hollencrest Capital Management45$5.52K0.00%00.0%Unchanged
Zions Bancorporation, National Association36$4.41K0.00%+13+56.5%Added
Harbour Investments, Inc.36$4.41K0.00%+17+89.5%Added
Wolff Wiese Magana LLC35$4.29K0.00%00.0%Unchanged
Huntington National Bank35$4.29K0.00%00.0%Unchanged
Farmers & Merchants Investments Inc35$4.29K0.00%00.0%Unchanged
Torren Management, LLC30$3.68K0.00%00.0%Unchanged
Marquette Asset Management, LLC28$3.43K0.00%00.0%Unchanged
Versant Capital Management, Inc27$3.31K0.00%00.0%Unchanged
Whipplewood Advisors, LLC22$2.70K0.00%00.0%Unchanged
UMA Financial Services, Inc.19$2.33K0.00%−2−9.5%Reduced
Triumph Capital Management18$2.21K0.00%00.0%Unchanged
Private Wealth Management Group, LLC16$1.96K0.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC15$1.84K0.00%+15New
Ankerstar Wealth, LLC12$1.47K0.00%00.0%Unchanged
Ameriflex Group, Inc.11$1.35K0.00%+11New
Prestige Wealth Management Group LLC10$1.23K0.00%+7+233.3%Added
Gilpin Wealth Management, LLC9$1.10K0.00%00.0%Unchanged
JFS Wealth Advisors, LLC9$1.10K0.00%+9New
Rossby Financial, LCC9$1.10K0.00%00.0%Unchanged
Action Point Financial Planning, LLC10$1.10K0.00%+10New
Hughes Financial Services, LLC8$9810.00%+2+33.3%Added
Noble Wealth Management PBC8$9810.00%+8New
Trust Co7$8580.00%00.0%Unchanged
Ares Financial Consulting, LLC6$7350.00%+6New
Rialto Wealth Management, LLC5$6130.00%+5New
DecisionPoint Financial, LLC4$5010.00%00.0%Unchanged
Kilter Group LLC4$4910.00%00.0%Unchanged
SJS Investment Consulting Inc.4$4910.00%+4New
Stone House Investment Management, LLC3$3680.00%+3New
Davis Capital Management3$3680.00%+3New
Abound Wealth Management2$2460.00%00.0%Unchanged
Walleye Capital LLC1$1230.00%+1New
Evolution Advisers, Inc.5$00.00%+5New
Citadel Advisors LLC0$00.00%−1,551,900−100.0%Sold out
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.0$00.00%−571,825−100.0%Sold out
Rubric Capital Management LP0$00.00%−427,998−100.0%Sold out
Vestal Point Capital, LP0$00.00%−326,159−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−282,436−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−50,000−100.0%Sold out
Royce & Associates LP0$00.00%−14,349−100.0%Sold out
Hussman Strategic Advisors, Inc.0$00.00%−10,500−100.0%Sold out
Nomura Holdings Inc0$00.00%−10,479−100.0%Sold out
Advisors Asset Management, Inc.0$00.00%−4,644−100.0%Sold out
Cynosure Management, LLC0$00.00%−4,635−100.0%Sold out
Dymon Asia Capital (Singapore) Pte. Ltd.0$00.00%−4,600−100.0%Sold out
Vident Advisory, LLC0$00.00%−4,481−100.0%Sold out
Abacus Wealth Partners, LLC0$00.00%−4,094−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−3,760−100.0%Sold out
Headlands Technologies LLC0$00.00%−2,957−100.0%Sold out
Sumitomo Mitsui Trust Holdings, Inc.0$00.00%−2,760−100.0%Sold out
Vise Technologies, Inc.0$00.00%−2,996−100.0%Sold out
GTS Securities LLC0$00.00%−2,416−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−2,012−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−1,429−100.0%Sold out
Federated Hermes, Inc.0$00.00%−1,001−100.0%Sold out
CFG Wealth Management Services, Inc.0$00.00%−611−100.0%Sold out
Toronto Dominion Bank0$00.00%−349−100.0%Sold out
Ameritas Advisory Services, LLC0$00.00%−334−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−173−100.0%Sold out
Sound Income Strategies, LLC0$00.00%−156−100.0%Sold out
Annis Gardner Whiting Capital Advisors, LLC0$00.00%−76−100.0%Sold out
MCF Advisors LLC0$00.00%−40−100.0%Sold out
Golden State Equity Partners0$00.00%−27−100.0%Sold out
Picton Mahoney Asset Management0$00.00%−25−100.0%Sold out
Pension & Wealth Management Advisors, Inc.0$00.00%−20−100.0%Sold out
Advisory Services Network, LLC0$00.00%−18−100.0%Sold out
MAI Capital Management0$00.00%−14−100.0%Sold out
Root Financial Partners, LLC0$00.00%−3−100.0%Sold out
Janus Henderson Group PLC––––Not filed
Skopos Labs, Inc.––––Not filed
CWM, LLC––––Not filed