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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
315
+27 vs. Q1 2026
Shares held
101.1M
+5.07M (+5.3%) vs. Q1 2026
Total value
$6.10B
+$538.5M (+9.7%) vs. Q1 2026
New holders
49
126 more added
Sold out
22
87 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 315 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2026: $6.10B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2026.

Institutions holding XENE in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
TFC Financial Management1$610.00%00.0%Unchanged
Larson Financial Group LLC3$1810.00%−49−94.2%Reduced
Caitong International Asset Management Co., Ltd4$2410.00%−3,326−99.9%Reduced
Hughes Financial Services, LLC5$3020.00%+1+25.0%Added
Cornerstone Financial Management LLC10$6040.00%+10New
SHP Wealth Management11$6640.00%+11New
Smartleaf Asset Management LLC12$7220.00%00.0%Unchanged
Ares Financial Consulting, LLC12$7240.00%+12New
UMA Financial Services, Inc.13$7850.00%00.0%Unchanged
Park Place Capital Corp16$9660.00%00.0%Unchanged
Bessemer Group Inc14$1.00K0.00%+14New
Massmutual Trust Co FSB17$1.03K0.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.20$1.21K0.00%+18+900.0%Added
Allworth Financial LP25$1.51K0.00%−13−34.2%Reduced
First Horizon Corp25$1.51K0.00%+1+4.2%Added
Parkside Financial Bank & Trust30$1.81K0.00%00.0%Unchanged
CoreCap Advisors, LLC30$1.81K0.00%+13+76.5%Added
Parallel Advisors, LLC31$1.87K0.00%−121−79.6%Reduced
CVA Family Office, LLC33$1.99K0.00%00.0%Unchanged
Hantz Financial Services, Inc.25$2.00K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC35$2.11K0.00%−42−54.5%Reduced
Ameritas Advisory Services, LLC35$2.11K0.00%+35New
SJS Investment Consulting Inc.37$2.23K0.00%+37New
Cape Investment Advisory, Inc.38$2.29K0.00%+38New
Silver Grove Financial Group, Inc.39$2.35K0.00%+39New
Continuum Advisory, LLC48$2.90K0.00%+48New
WPG Advisers, LLC63$3.80K0.00%+54+600.0%Added
Clearstead Advisors, LLC94$5.67K0.00%+94New
Danske Bank A/S100$6.04K0.00%00.0%Unchanged
Bell Investment Advisors, Inc100$6.04K0.00%00.0%Unchanged
Flagship Wealth Advisors, LLC100$6.04K0.00%+100New
Pinnacle Wealth Planning Services, Inc.129$7.79K0.00%+125+3,125.0%Added
TD Waterhouse Canada Inc.130$7.85K0.00%00.0%Unchanged
Covestor Ltd130$8.00K0.00%+120+1,200.0%Added
Rothschild Investment LLC136$8.21K0.00%+10+7.9%Added
SMA Capital LLC173$10.4K0.00%+34+24.5%Added
Rossby Financial, LCC181$10.9K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.200$12.1K0.00%00.0%Unchanged
IFG Advisory, LLC215$13.0K0.00%+215New
Farther Finance Advisors, LLC216$13.0K0.00%+27+14.3%Added
Versant Capital Management, Inc221$13.3K0.00%+221New
J.Safra Asset Management Corp222$13.4K0.00%−46−17.2%Reduced
National Bank of Canada235$14.2K0.00%00.0%Unchanged
US Bancorp258$15.6K0.00%−14−5.1%Reduced
Basecamp Wealth Advisors LLC280$16.9K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.332$20.0K0.00%−57−14.7%Reduced
Sterling Capital Management LLC345$20.8K0.00%−215−38.4%Reduced
Zions Bancorporation, National Association347$20.9K0.00%+42+13.8%Added
Huntington National Bank387$23.4K0.00%+99+34.4%Added
SRS Capital Advisors, Inc.441$26.6K0.00%+441New
Optiver Holding B.V.449$27.1K0.00%+449New
Vanguard Global Advisers, LLC493$29.8K0.00%−1−0.2%Reduced
GAMMA Investing LLC518$31.3K0.00%+145+38.9%Added
Ronald Blue Trust, Inc.724$43.7K0.00%−21−2.8%Reduced
Signaturefd, LLC760$45.9K0.00%+207+37.4%Added
Global Retirement Partners, LLC873$52.7K0.00%+873New
Kemnay Advisory Services Inc.876$52.9K0.01%+112+14.7%Added
Quantbot Technologies LP947$57.2K0.00%+785+484.6%Added
SBI Securities Co., Ltd.988$59.6K0.00%00.0%Unchanged
Axiom Investment Management LLC1,000$60.4K0.04%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,076$64.9K0.00%+800+289.9%Added
Nykredit A/S1,102$66.5K0.00%+1,102New
Harbor Investment Advisory, LLC1,393$84.1K0.01%+1,393New
GF Fund Management Co. Ltd.1,763$106.4K0.00%+28+1.6%Added
Nisa Investment Advisors, LLC1,830$110.5K0.00%+879+92.4%Added
IFP Advisors, Inc1,871$112.9K0.00%00.0%Unchanged
Natixis2,037$123.0K0.00%+2,037New
Eurizon Capital SGR S.p.A.2,826$170.1K0.00%+177+6.7%Added
Bayforest Capital Ltd3,129$188.9K0.17%+2,574+463.8%Added
Jones Financial Companies LLLP3,268$195.2K0.00%+869+36.2%Added
Susquehanna Fundamental Investments, LLC3,405$205.5K0.00%+3,405New
Inscription Capital, LLC3,431$207.1K0.02%+3,431New
Oxford Asset Management LLP3,547$214.1K0.11%−3,337−48.5%Reduced
Snowden Capital Advisors LLC3,782$228.3K0.01%−441−10.4%Reduced
Abel Hall, LLC3,809$229.9K0.04%+3,809New
Cetera Investment Advisers3,898$235.3K0.00%+274+7.6%Added
FNY Investment Advisers, LLC4,000$241.0K0.09%−200−4.8%Reduced
Tower Research Capital LLC (TRC)4,164$251.3K0.01%−1,941−31.8%Reduced
Mercer Global Advisors Inc4,193$253.1K0.00%+4,193New
PSP Research LLC4,200$253.5K0.13%00.0%Unchanged
Oppenheimer Asset Management Inc.4,217$254.5K0.00%−108−2.5%Reduced
Mirae Asset Global Investments Co., Ltd.4,323$260.9K0.00%−16−0.4%Reduced
LPL Financial LLC4,838$292.0K0.00%−126−2.5%Reduced
Northwestern Mutual Wealth Management Co5,000$301.8K0.00%00.0%Unchanged
Advisors Asset Management, Inc.5,086$307.0K0.00%−1,875−26.9%Reduced
Aigen Investment Management, LP5,218$315.0K0.09%+1,095+26.6%Added
Citizens Financial Group Inc5,291$319.4K0.00%+328+6.6%Added
Swiss Life Asset Management Ltd5,319$321.1K0.00%+472+9.7%Added
Ensign Peak Advisors, Inc5,394$325.6K0.00%+200+3.9%Added
CAPROCK Group, Inc.5,406$326.3K0.01%+115+2.2%Added
CIBC Bancorp USA Inc.5,423$327.3K0.00%+1,074+24.7%Added
Captrust Financial Advisors5,572$336.3K0.00%+5,572New
SG Americas Securities, LLC5,982$361.0K0.00%−3,137−34.4%Reduced
Letson Investment Management, Inc.6,000$362.2K0.13%00.0%Unchanged
Virtus Investment Advisers, Inc.6,281$379.1K0.09%+93+1.5%Added
Gsa Capital Partners LLP6,293$380.0K0.02%+6,293New
Blair William & Co6,730$406.2K0.00%+6,730New
PenderFund Capital Management Ltd.6,850$413.5K0.05%00.0%Unchanged
AQR Capital Management LLC7,263$438.4K0.00%−16−0.2%Reduced
Principal Financial Group Inc7,506$453.1K0.00%+1,262+20.2%Added