Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 290
- +49 vs. Q4 2025
- Shares held
- 100.2M
- +16.7M (+20.0%) vs. Q4 2025
- Total value
- $5.80B
- +$2.06B (+55.0%) vs. Q4 2025
- New holders
- 82
- 123 more added
- Sold out
- 33
- 60 more reduced
4 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Granahan Investment Management Inc | 104,478 | $6.08M | 0.29% | +11,700+12.6% | Added |
| Rhumbline Advisers | 101,785 | $5.92M | 0.01% | +11,642+12.9% | Added |
| Burkehill Global Management, LP | 100,000 | $5.82M | 0.29% | +100,000 | New |
| UBS Group AG | 99,624 | $5.79M | 0.00% | +47,085+89.6% | Added |
| Axiom Investors LLC | 99,568 | $5.79M | 0.06% | +99,568 | New |
| California State Teachers Retirement System | 92,747 | $5.39M | 0.01% | +36,183+64.0% | Added |
| Royal Bank of Canada | 90,387 | $5.25M | 0.00% | +630+0.7% | Added |
| Raymond James Financial Inc | 88,598 | $5.15M | 0.00% | +5,343+6.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 85,388 | $4.97M | 0.09% | +12,431+17.0% | Added |
| BNP Paribas Arbitrage, SA | 80,392 | $4.67M | 0.00% | −13,070−14.0% | Reduced |
| Aquatic Capital Management LLC | 79,199 | $4.61M | 0.13% | +79,199 | New |
| Ameriprise Financial Inc | 78,905 | $4.59M | 0.00% | −30,639−28.0% | Reduced |
| Schroder Investment Management Group | 81,156 | $4.51M | 0.00% | 00.0% | Unchanged |
| Vanguard Fiduciary Trust Co | 75,117 | $4.37M | 0.00% | +75,117 | New |
| Seven Grand Managers, LLC | 75,000 | $4.36M | 0.29% | +75,000 | New |
| Vanguard Asset Management, Ltd | 74,481 | $4.33M | 0.00% | +74,481 | New |
| Legal & General Group Plc | 73,489 | $4.27M | 0.00% | +3,224+4.6% | Added |
| Voya Investment Management LLC | 68,363 | $3.98M | 0.00% | +7,505+12.3% | Added |
| Alps Advisors Inc | 67,723 | $3.94M | 0.02% | +4,421+7.0% | Added |
| Trexquant Investment LP | 67,361 | $3.92M | 0.03% | +67,361 | New |
| EAM Investors, LLC | 66,550 | $3.87M | 0.45% | +66,550 | New |
| Vanguard Capital Management LLC | 65,961 | $3.84M | 0.00% | +65,961 | New |
| Artia Global Partners LP | 65,000 | $3.78M | 0.85% | +25,000+62.5% | Added |
| Castleark Management LLC | 64,563 | $3.75M | 0.12% | +64,563 | New |
| Atika Capital Management LLC | 59,900 | $3.48M | 0.55% | −32,606−35.2% | Reduced |
| Invesco Ltd. | 59,103 | $3.44M | 0.00% | +8,156+16.0% | Added |
| LMR Partners LLP | 56,200 | $3.27M | 0.03% | +56,200 | New |
| Quantinno Capital Management LP | 55,444 | $3.22M | 0.01% | +30,816+125.1% | Added |
| Verition Fund Management LLC | 55,000 | $3.20M | 0.03% | −38,756−41.3% | Reduced |
| Palo Alto Investors LP | 51,345 | $2.99M | 0.46% | −45,174−46.8% | Reduced |
| Lazard Asset Management LLC | 50,755 | $2.95M | 0.00% | −27,908−35.5% | Reduced |
| Victory Capital Management Inc | 49,970 | $2.91M | 0.00% | +49,970 | New |
| HighVista Strategies LLC | 49,050 | $2.85M | 0.79% | +49,050 | New |
| Erste Asset Management GmbH | 50,000 | $2.78M | 0.03% | 00.0% | Unchanged |
| MetLife Investment Management | 47,343 | $2.75M | 0.01% | +5,318+12.7% | Added |
| Nomura Asset Management International Inc. | 47,041 | $2.73M | 0.00% | −916−1.9% | Reduced |
| Qube Research & Technologies Ltd | 44,044 | $2.56M | 0.00% | +44,044 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 40,513 | $2.36M | 0.00% | +5,203+14.7% | Added |
| DekaBank Deutsche Girozentrale | 39,000 | $2.20M | 0.00% | 00.0% | Unchanged |
| Legato Capital Management LLC | 36,641 | $2.13M | 0.19% | −397−1.1% | Reduced |
| Envestnet Asset Management Inc | 36,068 | $2.10M | 0.00% | +267+0.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 35,204 | $2.05M | 0.00% | +9,615+37.6% | Added |
| ACT Capital Management, LLC | 33,500 | $1.95M | 1.53% | +33,500 | New |
| TLS Advisors LLC | 30,956 | $1.80M | 4.27% | +12,098+64.2% | Added |
| Calamos Advisors LLC | 30,374 | $1.77M | 0.01% | +30,374 | New |
| Creative Planning | 29,818 | $1.73M | 0.00% | +10,618+55.3% | Added |
| Handelsbanken Fonder AB | 29,800 | $1.73M | 0.01% | 00.0% | Unchanged |
| CI Private Wealth, LLC | 28,302 | $1.65M | 0.00% | +28,302 | New |
| Rhenman & Partners Asset Management AB | 28,000 | $1.63M | 0.20% | −111,000−79.9% | Reduced |
| XTX Topco Ltd | 28,000 | $1.63M | 0.03% | +6,502+30.2% | Added |
| TD Asset Management Inc | 27,074 | $1.57M | 0.00% | −11,074−29.0% | Reduced |
| Swedbank AB | 26,200 | $1.52M | 0.00% | +26,200 | New |
| SummitTX Capital, L.P. | 26,186 | $1.52M | 0.05% | +26,186 | New |
| Bamco Inc | 25,000 | $1.45M | 0.00% | −5,000−16.7% | Reduced |
| Vestmark Advisory Solutions, Inc. | 24,025 | $1.40M | 0.02% | +2,141+9.8% | Added |
| Rathbone Brothers plc | 23,666 | $1.38M | 0.01% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 23,405 | $1.36M | 0.01% | +3,277+16.3% | Added |
| HighMark Wealth Management LLC | 23,000 | $1.34M | 0.54% | 00.0% | Unchanged |
| Arizona State Retirement System | 21,869 | $1.27M | 0.01% | +5,690+35.2% | Added |
| Manufacturers Life Insurance Company, The | 21,684 | $1.26M | 0.00% | −10,938−33.5% | Reduced |
| Sanders Morris Harris LLC | 21,500 | $1.25M | 0.20% | +21,500 | New |
| Teachers Retirement System of the State of Kentucky | 21,133 | $1.23M | 0.01% | +21,133 | New |
| Birchview Capital, LP | 21,000 | $1.22M | 0.70% | 00.0% | Unchanged |
| Assetmark, Inc | 20,272 | $1.18M | 0.00% | −997−4.7% | Reduced |
| Vanguard Investments Australia, Ltd. | 19,954 | $1.16M | 0.00% | +19,954 | New |
| State of New Jersey Common Pension Fund D | 19,807 | $1.15M | 0.00% | +69+0.3% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 19,439 | $1.13M | 0.00% | +19,439 | New |
| State Board of Administration of Florida Retirement System | 19,097 | $1.11M | 0.00% | +19,097 | New |
| Intech Investment Management LLC | 19,062 | $1.11M | 0.01% | −6,778−26.2% | Reduced |
| CIBC World Markets Inc. | 18,960 | $1.10M | 0.00% | +5,500+40.9% | Added |
| D. E. Shaw & Co., Inc. | 18,940 | $1.10M | 0.00% | −11,911−38.6% | Reduced |
| Martingale Asset Management L P | 18,806 | $1.09M | 0.03% | +18,806 | New |
| Susquehanna Portfolio Strategies, LLC | 18,468 | $1.07M | 0.02% | +18,468 | New |
| Campbell & CO Investment Adviser LLC | 18,156 | $1.06M | 0.06% | +2,051+12.7% | Added |
| Amundi | 18,013 | $1.05M | 0.00% | +13,404+290.8% | Added |
| KLP Kapitalforvaltning AS | 17,600 | $1.02M | 0.00% | +5,300+43.1% | Added |
| Stifel Financial Corp | 16,718 | $972.2K | 0.00% | −830−4.7% | Reduced |
| ProShare Advisors LLC | 16,250 | $944.9K | 0.00% | −1,029−6.0% | Reduced |
| China Universal Asset Management Co., Ltd. | 14,763 | $858.5K | 0.06% | +2,171+17.2% | Added |
| Hudson Bay Capital Management LP | 14,072 | $818.3K | 0.00% | +14,072 | New |
| Brinker Capital Investments, LLC | 13,817 | $803.4K | 0.01% | −590−4.1% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 14,400 | $799.9K | 0.03% | 00.0% | Unchanged |
| Neo Ivy Capital Management | 13,710 | $797.2K | 0.21% | +6,233+83.4% | Added |
| Prudential Financial Inc | 13,010 | $756.5K | 0.00% | +13,010 | New |
| Citigroup Inc | 12,151 | $706.6K | 0.00% | +4,790+65.1% | Added |
| Brevan Howard Capital Management LP | 12,041 | $700.2K | 0.01% | +12,041 | New |
| Public Employees Retirement Association of Colorado | 10,633 | $618.0K | 0.00% | 00.0% | Unchanged |
| Covalis Capital LLP | 10,000 | $581.5K | 0.04% | +10,000 | New |
| Elmwood Wealth Management, Inc. | 9,807 | $570.3K | 0.16% | −950−8.8% | Reduced |
| Engineers Gate Manager LP | 9,326 | $542.3K | 0.01% | +9,326 | New |
| First Trust Advisors LP | 9,133 | $531.1K | 0.00% | +2,772+43.6% | Added |
| Thrivent Financial for Lutherans | 9,122 | $531.0K | 0.00% | +3,539+63.4% | Added |
| SG Americas Securities, LLC | 9,119 | $530.0K | 0.00% | +2,042+28.9% | Added |
| J. Safra Sarasin Holding AG | 9,071 | $527.5K | 0.01% | −4,510−33.2% | Reduced |
| EntryPoint Capital, LLC | 8,832 | $513.6K | 0.15% | +3,804+75.7% | Added |
| JustInvest LLC | 8,761 | $509.5K | 0.01% | +4,228+93.3% | Added |
| Xponance, Inc. | 8,465 | $492.2K | 0.00% | +2,490+41.7% | Added |
| The PNC Financial Services Group, Inc. | 8,097 | $470.8K | 0.00% | +1,523+23.2% | Added |
| Allianz Asset Management GmbH | 7,600 | $441.9K | 0.00% | −1,800−19.1% | Reduced |
| Teacher Retirement System of Texas | 7,599 | $441.9K | 0.00% | −1,033−12.0% | Reduced |