Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- +3 vs. Q2 2025
- Shares held
- 70.7M
- −267.3K (−0.4%) vs. Q2 2025
- Total value
- $4.70B
- +$772.8M (+19.7%) vs. Q2 2025
- New holders
- 42
- 84 more added
- Sold out
- 39
- 109 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SG Americas Securities, LLC | 41,246 | $2.74M | 0.01% | +39,322+2,043.8% | Added |
| State of Wisconsin Investment Board | 40,906 | $2.72M | 0.01% | +7,918+24.0% | Added |
| State of New Jersey Common Pension Fund D | 37,956 | $2.52M | 0.01% | −3,069−7.5% | Reduced |
| Creative Planning | 36,214 | $2.41M | 0.00% | +6,010+19.9% | Added |
| MetLife Investment Management | 33,846 | $2.25M | 0.01% | −924−2.7% | Reduced |
| Exchange Traded Concepts, LLC | 33,552 | $2.23M | 0.02% | −13,839−29.2% | Reduced |
| Illinois Municipal Retirement Fund | 33,183 | $2.20M | 0.03% | +5,614+20.4% | Added |
| SummitTX Capital, L.P. | 31,490 | $2.09M | 0.09% | +31,490 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 30,871 | $2.05M | 0.00% | −4,970−13.9% | Reduced |
| State of Alaska, Department of Revenue | 29,425 | $1.95M | 0.02% | −7,481−20.3% | Reduced |
| Alps Advisors Inc | 29,203 | $1.94M | 0.01% | −11,017−27.4% | Reduced |
| Louisiana State Employees Retirement System | 26,900 | $1.79M | 0.03% | −2,100−7.2% | Reduced |
| State of Tennessee, Treasury Department | 26,490 | $1.76M | 0.01% | +500+1.9% | Added |
| Envestnet Asset Management Inc | 24,258 | $1.61M | 0.00% | +380+1.6% | Added |
| Artia Global Partners LP | 22,951 | $1.52M | 0.27% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 22,198 | $1.47M | 0.01% | −15,089−40.5% | Reduced |
| Intech Investment Management LLC | 21,643 | $1.44M | 0.01% | −12,310−36.3% | Reduced |
| Hussman Strategic Advisors, Inc. | 21,000 | $1.40M | 0.30% | −10,500−33.3% | Reduced |
| Bellevue Group AG | 20,581 | $1.37M | 0.03% | +1,109+5.7% | Added |
| Superstring Capital Management LP | 20,358 | $1.35M | 1.33% | +20,358 | New |
| Capital Fund Management S.A. | 20,348 | $1.35M | 0.01% | −29,457−59.1% | Reduced |
| Polen Capital Management LLC | 20,325 | $1.35M | 0.00% | +4,326+27.0% | Added |
| Allianz Asset Management GmbH | 19,678 | $1.31M | 0.00% | −2,622−11.8% | Reduced |
| New York State Common Retirement Fund | 19,582 | $1.30M | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 18,900 | $1.26M | 0.00% | +1,900+11.2% | Added |
| Guggenheim Capital LLC | 18,583 | $1.23M | 0.01% | −625−3.3% | Reduced |
| Winton Group Ltd | 18,561 | $1.23M | 0.05% | +1,128+6.5% | Added |
| Yousif Capital Management, LLC | 18,426 | $1.22M | 0.01% | −4,978−21.3% | Reduced |
| Profund Advisors LLC | 18,157 | $1.21M | 0.04% | −917−4.8% | Reduced |
| J. Goldman & Co LP | 18,068 | $1.20M | 0.05% | −17,760−49.6% | Reduced |
| Glenmede Investment Management, LP | 18,000 | $1.20M | 0.01% | −3,434−16.0% | Reduced |
| STRS Ohio | 17,800 | $1.18M | 0.00% | −1,800−9.2% | Reduced |
| Teachers Retirement System of the State of Kentucky | 17,296 | $1.15M | 0.01% | −1,436−7.7% | Reduced |
| Royce & Associates LP | 16,989 | $1.13M | 0.01% | +4,734+38.6% | Added |
| Natixis Advisors, L.P. | 16,855 | $1.12M | 0.00% | +3,413+25.4% | Added |
| Amalgamated Bank | 16,826 | $1.12M | 0.01% | −717−4.1% | Reduced |
| Comerica Bank | 16,395 | $1.09M | 0.00% | −4,896−23.0% | Reduced |
| State Board of Administration of Florida Retirement System | 16,303 | $1.08M | 0.00% | 00.0% | Unchanged |
| Moran Wealth Management, LLC | 16,212 | $1.08M | 0.03% | +451+2.9% | Added |
| Police & Firemen's Retirement System of New Jersey | 16,119 | $1.07M | 0.01% | +2,663+19.8% | Added |
| China Universal Asset Management Co., Ltd. | 15,905 | $1.06M | 0.09% | −3,003−15.9% | Reduced |
| Virginia Retirement Systems Et Al | 15,600 | $1.04M | 0.01% | −3,400−17.9% | Reduced |
| DekaBank Deutsche Girozentrale | 15,800 | $1.03M | 0.00% | 00.0% | Unchanged |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 14,893 | $989.3K | 0.00% | −1,020−6.4% | Reduced |
| Jain Global LLC | 14,850 | $986.5K | 0.01% | +14,850 | New |
| Arizona State Retirement System | 14,669 | $974.5K | 0.01% | +343+2.4% | Added |
| Weiss Asset Management LP | 14,310 | $950.6K | 0.01% | +14,310 | New |
| Mariner, LLC | 13,551 | $900.2K | 0.00% | −2,150−13.7% | Reduced |
| Pathstone Holdings, LLC | 13,362 | $887.7K | 0.00% | +5,167+63.1% | Added |
| Erste Asset Management GmbH | 13,500 | $879.4K | 0.01% | 00.0% | Unchanged |
| Oregon Public Employees Retirement Fund | 13,200 | $876.9K | 0.01% | −1,000−7.0% | Reduced |
| ProShare Advisors LLC | 13,187 | $876.0K | 0.00% | −2,189−14.2% | Reduced |
| BNP Paribas Arbitrage, SA | 13,137 | $872.7K | 0.00% | +3,998+43.7% | Added |
| Teacher Retirement System of Texas | 12,106 | $804.2K | 0.00% | −1,099−8.3% | Reduced |
| Persistent Asset Partners Ltd | 11,780 | $782.5K | 0.57% | −5,740−32.8% | Reduced |
| Franklin Street Advisors Inc | 11,300 | $750.7K | 0.04% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 10,986 | $729.8K | 0.00% | −12,150−52.5% | Reduced |
| Cambria Investment Management, L.P. | 10,944 | $727.0K | 0.04% | +2,187+25.0% | Added |
| KLP Kapitalforvaltning AS | 10,400 | $690.9K | 0.00% | 00.0% | Unchanged |
| Cache Advisors, LLC | 10,143 | $673.8K | 0.12% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,073 | $669.1K | 0.00% | 00.0% | Unchanged |
| HRT Financial LP | 9,470 | $629.0K | 0.00% | +9,470 | New |
| Toroso Investments, LLC | 8,945 | $594.2K | 0.00% | −14,832−62.4% | Reduced |
| Resona Asset Management Co.,Ltd. | 8,731 | $580.0K | 0.00% | +8,731 | New |
| Cerity Partners LLC | 8,618 | $572.5K | 0.00% | −1,104−11.4% | Reduced |
| HighTower Advisors, LLC | 8,613 | $572.2K | 0.00% | −1,367−13.7% | Reduced |
| AQR Capital Management LLC | 8,570 | $569.3K | 0.00% | −8,839−50.8% | Reduced |
| Maryland State Retirement & Pension System | 8,407 | $558.5K | 0.01% | −9,809−53.8% | Reduced |
| Aviva PLC | 7,792 | $517.6K | 0.00% | −1,643−17.4% | Reduced |
| Capstone Investment Advisors, LLC | 7,676 | $509.9K | 0.00% | +689+9.9% | Added |
| Brevan Howard Capital Management LP | 7,598 | $504.7K | 0.01% | −19,396−71.9% | Reduced |
| XTX Topco Ltd | 7,260 | $482.3K | 0.03% | −72−1.0% | Reduced |
| New Vernon Capital Holdings II LLC | 7,198 | $478.2K | 0.22% | 00.0% | Unchanged |
| CWM Advisors, LLC | 6,938 | $460.9K | 0.04% | −346−4.8% | Reduced |
| Brinker Capital Investments, LLC | 6,928 | $460.2K | 0.00% | +328+5.0% | Added |
| Mutual of America Capital Management LLC | 6,551 | $435.2K | 0.00% | −1,411−17.7% | Reduced |
| CIBC Bancorp USA Inc. | 6,205 | $412.2K | 0.00% | +6,205 | New |
| King Wealth | 6,000 | $399.0K | 0.05% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 6,001 | $399.0K | 0.00% | +6,001 | New |
| Russell Investments Group, Ltd. | 5,924 | $393.5K | 0.00% | +5,795+4,492.2% | Added |
| Gsa Capital Partners LLP | 5,884 | $391.0K | 0.03% | +5,884 | New |
| US Bancorp | 5,852 | $388.7K | 0.00% | +629+12.0% | Added |
| Advantage Alpha Capital Partners LP | 5,804 | $385.6K | 0.12% | −1,168−16.8% | Reduced |
| Palumbo Wealth Management LLC | 5,268 | $350.0K | 0.11% | −2,262−30.0% | Reduced |
| Kestra Advisory Services, LLC | 5,223 | $347.0K | 0.00% | −540−9.4% | Reduced |
| CAPROCK Group, Inc. | 5,802 | $342.6K | 0.01% | +5,802 | New |
| Vident Advisory, LLC | 5,070 | $336.8K | 0.00% | +5,070 | New |
| Burney Co | 5,064 | $336.4K | 0.01% | −1,254−19.8% | Reduced |
| Vestcor Inc | 5,022 | $334.0K | 0.01% | +5,022 | New |
| LPL Financial LLC | 4,994 | $331.8K | 0.00% | +176+3.7% | Added |
| Ameritas Investment Partners, Inc. | 4,863 | $323.0K | 0.01% | −1,049−17.7% | Reduced |
| Advisors Asset Management, Inc. | 4,706 | $312.6K | 0.01% | −18−0.4% | Reduced |
| Cornerstone Investment Partners, LLC | 4,632 | $307.7K | 0.01% | −348−7.0% | Reduced |
| Camden Capital, LLC | 4,535 | $301.3K | 0.02% | +4,535 | New |
| Xponance, Inc. | 4,534 | $301.2K | 0.00% | +28+0.6% | Added |
| Baader Bank INC | 4,300 | $285.6K | 0.02% | +4,300 | New |
| Bessemer Group Inc | 4,275 | $283.0K | 0.00% | +3,771+748.2% | Added |
| Mackenzie Financial Corp | 4,064 | $270.0K | 0.00% | −18,393−81.9% | Reduced |
| Quantinno Capital Management LP | 4,047 | $268.8K | 0.00% | +4,047 | New |
| Nisa Investment Advisors, LLC | 3,985 | $264.7K | 0.00% | +82+2.1% | Added |