Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- +3 vs. Q2 2025
- Shares held
- 70.7M
- −267.3K (−0.4%) vs. Q2 2025
- Total value
- $4.70B
- +$772.8M (+19.7%) vs. Q2 2025
- New holders
- 42
- 84 more added
- Sold out
- 39
- 109 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| DecisionPoint Financial, LLC | 4 | $256 | 0.00% | 00.0% | Unchanged |
| Abound Wealth Management | 4 | $266 | 0.00% | 00.0% | Unchanged |
| Kilter Group LLC | 4 | $266 | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 9 | $598 | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 9 | $598 | 0.00% | +9 | New |
| Jones Financial Companies LLLP | 20 | $1.35K | 0.00% | 00.0% | Unchanged |
| Atlantic Trust, LLC | 21 | $1.40K | 0.00% | 00.0% | Unchanged |
| Montag A & Associates Inc | 25 | $1.66K | 0.00% | +25 | New |
| Versant Capital Management, Inc | 27 | $1.79K | 0.00% | −2−6.9% | Reduced |
| Marquette Asset Management, LLC | 28 | $1.86K | 0.00% | +28 | New |
| Picton Mahoney Asset Management | 25 | $2.00K | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 32 | $2.13K | 0.00% | −4−11.1% | Reduced |
| Bare Financial Services, Inc | 34 | $2.26K | 0.00% | +11+47.8% | Added |
| Farmers & Merchants Investments Inc | 35 | $2.33K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 35 | $2.33K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 39 | $2.59K | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 45 | $2.99K | 0.00% | 00.0% | Unchanged |
| Wealthspire Advisors, LLC | 48 | $3.19K | 0.00% | +48 | New |
| Raffa Wealth Management, LLC | 60 | $3.99K | 0.00% | 00.0% | Unchanged |
| Annis Gardner Whiting Capital Advisors, LLC | 76 | $5.05K | 0.00% | 00.0% | Unchanged |
| WPG Advisers, LLC | 78 | $5.18K | 0.00% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 81 | $5.38K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 81 | $5.38K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 83 | $5.51K | 0.00% | +83 | New |
| Rothschild Investment LLC | 85 | $5.65K | 0.00% | −25−22.7% | Reduced |
| MAI Capital Management | 86 | $5.71K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 92 | $6.11K | 0.00% | +92 | New |
| Danske Bank A/S | 100 | $6.64K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 102 | $6.78K | 0.00% | +5+5.2% | Added |
| Massmutual Trust Co FSB | 119 | $7.91K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 141 | $9.37K | 0.00% | −2−1.4% | Reduced |
| Farther Finance Advisors, LLC | 141 | $9.37K | 0.00% | +48+51.6% | Added |
| Signaturefd, LLC | 149 | $9.90K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 154 | $10.2K | 0.00% | +128+492.3% | Added |
| Optiver Holding B.V. | 169 | $11.2K | 0.00% | +169 | New |
| Daiwa Securities Group Inc. | 190 | $13.0K | 0.00% | −25−11.6% | Reduced |
| Clearstead Advisors, LLC | 200 | $13.3K | 0.00% | +90+81.8% | Added |
| Rise Advisors, LLC | 224 | $14.9K | 0.01% | 00.0% | Unchanged |
| Allworth Financial LP | 247 | $16.4K | 0.00% | +130+111.1% | Added |
| Umb Bank N A | 258 | $17.1K | 0.00% | +59+29.6% | Added |
| Assetmark, Inc | 280 | $18.6K | 0.00% | −10−3.4% | Reduced |
| Hantz Financial Services, Inc. | 295 | $20.0K | 0.00% | +152+106.3% | Added |
| Fifth Third Bancorp | 307 | $20.4K | 0.00% | +96+45.5% | Added |
| Global Retirement Partners, LLC | 316 | $21.0K | 0.00% | 00.0% | Unchanged |
| Salomon & Ludwin, LLC | 442 | $28.7K | 0.00% | +442 | New |
| EverSource Wealth Advisors, LLC | 540 | $35.9K | 0.00% | +314+138.9% | Added |
| CWM, LLC | 556 | $37.0K | 0.00% | −53−8.7% | Reduced |
| Truvestments Capital LLC | 722 | $48.0K | 0.01% | +72+11.1% | Added |
| Abich Financial Wealth Management LLC | 932 | $61.9K | 0.02% | +932 | New |
| Wexford Capital LP | 941 | $62.5K | 0.02% | −2,374−71.6% | Reduced |
| Covestor Ltd | 990 | $66.0K | 0.04% | −755−43.3% | Reduced |
| GF Fund Management Co. Ltd. | 1,338 | $88.9K | 0.00% | −188−12.3% | Reduced |
| Quadrant Capital Group LLC | 1,352 | $89.8K | 0.00% | +1,352 | New |
| Advisor Group Holdings, Inc. | 1,391 | $91.0K | 0.00% | +206+17.4% | Added |
| Smartleaf Asset Management LLC | 1,403 | $91.4K | 0.01% | +146+11.6% | Added |
| KBC Group NV | 1,574 | $105.0K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 1,618 | $107.5K | 0.01% | +1,618 | New |
| GAMMA Investing LLC | 1,648 | $109.5K | 0.01% | +571+53.0% | Added |
| Virtus Investment Advisers, Inc. | 2,020 | $134.2K | 0.04% | +350+21.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,405 | $159.8K | 0.00% | +11+0.5% | Added |
| The PNC Financial Services Group, Inc. | 2,738 | $181.9K | 0.00% | +324+13.4% | Added |
| NBC Securities, Inc. | 2,958 | $196.5K | 0.02% | +393+15.3% | Added |
| Rockefeller Capital Management L.P. | 2,980 | $198.0K | 0.00% | +2,980 | New |
| Fox Run Management, L.L.C. | 3,103 | $206.1K | 0.03% | +3,103 | New |
| ISAM Funds (UK) Ltd | 3,118 | $207.1K | 0.04% | +3,118 | New |
| JustInvest LLC | 3,298 | $219.1K | 0.00% | +3,298 | New |
| Quantbot Technologies LP | 3,303 | $219.4K | 0.01% | +3,303 | New |
| Captrust Financial Advisors | 3,312 | $220.0K | 0.00% | +3,312 | New |
| Verdence Capital Advisors LLC | 3,038 | $228.6K | 0.01% | +3,038 | New |
| Wealth Enhancement Advisory Services, LLC | 3,511 | $229.9K | 0.00% | +3,511 | New |
| FORA Capital, LLC | 3,685 | $244.8K | 0.04% | +3,685 | New |
| Velan Capital Investment Management LP | 3,700 | $245.8K | 0.23% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 3,801 | $252.5K | 0.01% | −1,538−28.8% | Reduced |
| Bank of Montreal | 3,864 | $256.7K | 0.00% | −5,714−59.7% | Reduced |
| Crossmark Global Holdings, Inc. | 3,966 | $263.5K | 0.00% | −99−2.4% | Reduced |
| Nisa Investment Advisors, LLC | 3,985 | $264.7K | 0.00% | +82+2.1% | Added |
| Quantinno Capital Management LP | 4,047 | $268.8K | 0.00% | +4,047 | New |
| Mackenzie Financial Corp | 4,064 | $270.0K | 0.00% | −18,393−81.9% | Reduced |
| Bessemer Group Inc | 4,275 | $283.0K | 0.00% | +3,771+748.2% | Added |
| Baader Bank INC | 4,300 | $285.6K | 0.02% | +4,300 | New |
| Xponance, Inc. | 4,534 | $301.2K | 0.00% | +28+0.6% | Added |
| Camden Capital, LLC | 4,535 | $301.3K | 0.02% | +4,535 | New |
| Cornerstone Investment Partners, LLC | 4,632 | $307.7K | 0.01% | −348−7.0% | Reduced |
| Advisors Asset Management, Inc. | 4,706 | $312.6K | 0.01% | −18−0.4% | Reduced |
| Ameritas Investment Partners, Inc. | 4,863 | $323.0K | 0.01% | −1,049−17.7% | Reduced |
| LPL Financial LLC | 4,994 | $331.8K | 0.00% | +176+3.7% | Added |
| Vestcor Inc | 5,022 | $334.0K | 0.01% | +5,022 | New |
| Burney Co | 5,064 | $336.4K | 0.01% | −1,254−19.8% | Reduced |
| Vident Advisory, LLC | 5,070 | $336.8K | 0.00% | +5,070 | New |
| CAPROCK Group, Inc. | 5,802 | $342.6K | 0.01% | +5,802 | New |
| Kestra Advisory Services, LLC | 5,223 | $347.0K | 0.00% | −540−9.4% | Reduced |
| Palumbo Wealth Management LLC | 5,268 | $350.0K | 0.11% | −2,262−30.0% | Reduced |
| Advantage Alpha Capital Partners LP | 5,804 | $385.6K | 0.12% | −1,168−16.8% | Reduced |
| US Bancorp | 5,852 | $388.7K | 0.00% | +629+12.0% | Added |
| Gsa Capital Partners LLP | 5,884 | $391.0K | 0.03% | +5,884 | New |
| Russell Investments Group, Ltd. | 5,924 | $393.5K | 0.00% | +5,795+4,492.2% | Added |
| King Wealth | 6,000 | $399.0K | 0.05% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 6,001 | $399.0K | 0.00% | +6,001 | New |
| CIBC Bancorp USA Inc. | 6,205 | $412.2K | 0.00% | +6,205 | New |
| Mutual of America Capital Management LLC | 6,551 | $435.2K | 0.00% | −1,411−17.7% | Reduced |