Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 356
- +9 vs. Q3 2024
- Shares held
- 160.5M
- +3.10M (+2.0%) vs. Q3 2024
- Total value
- $5.61B
- −$692.3M (−11.0%) vs. Q3 2024
- New holders
- 58
- 119 more added
- Sold out
- 49
- 121 more reduced
7 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Significant Wealth Partners LLC | 10,905 | $381.2K | 0.20% | +10,905 | New |
| Suvretta Capital Management, LLC | 10,800 | $377.6K | 0.01% | 00.0% | Unchanged |
| Annis Gardner Whiting Capital Advisors, LLC | 10,736 | $375.3K | 0.11% | +800+8.1% | Added |
| Harbor Advisors LLC | 10,500 | $367.1K | 0.06% | +5,000+90.9% | Added |
| Amalgamated Bank | 10,292 | $360.0K | 0.00% | +335+3.4% | Added |
| Wiley Bros.-Aintree Capital, LLC | 10,317 | $359.1K | 0.00% | +711+7.4% | Added |
| Landscape Capital Management, L.L.C. | 10,270 | $359.0K | 0.04% | −15,165−59.6% | Reduced |
| Syon Capital LLC | 10,119 | $353.8K | 0.03% | +10,119 | New |
| Cypress Capital, LLC | 10,000 | $349.6K | 0.10% | 00.0% | Unchanged |
| Walleye Trading LLC | 9,920 | $346.8K | 0.01% | +6,307+174.6% | Added |
| Janney Montgomery Scott LLC | 9,840 | $344.0K | 0.00% | −1,454−12.9% | Reduced |
| Fifth Third Bancorp | 9,531 | $333.2K | 0.00% | −41−0.4% | Reduced |
| Torno Capital, LLC | 9,500 | $332.1K | 0.07% | +4,500+90.0% | Added |
| Virtus ETF Advisers LLC | 9,448 | $330.3K | 0.13% | +1,439+18.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 9,450 | $330.0K | 0.00% | +1,625+20.8% | Added |
| Y-Intercept (Hong Kong) Ltd | 9,407 | $328.9K | 0.02% | −10,734−53.3% | Reduced |
| Jones Financial Companies LLLP | 9,338 | $326.5K | 0.00% | +2,614+38.9% | Added |
| MetLife Investment Management | 9,160 | $320.2K | 0.00% | −203−2.2% | Reduced |
| Wolverine Trading, LLC | 8,847 | $308.9K | 0.01% | −2,764−23.8% | Reduced |
| Teza Capital Management LLC | 8,525 | $298.0K | 0.05% | −2,075−19.6% | Reduced |
| Utah Retirement Systems | 8,400 | $293.7K | 0.00% | 00.0% | Unchanged |
| Man Group plc | 8,315 | $290.7K | 0.00% | −587,948−98.6% | Reduced |
| Maryland State Retirement & Pension System | 8,284 | $289.6K | 0.01% | 00.0% | Unchanged |
| International Assets Investment Management, LLC | 8,207 | $284.7K | 0.02% | −320,565−97.5% | Reduced |
| Colony Group, LLC | 8,055 | $281.6K | 0.00% | +2,359+41.4% | Added |
| Cambridge Investment Research Advisors, Inc. | 7,765 | $271.0K | 0.00% | −1,973−20.3% | Reduced |
| AlphaCentric Advisors LLC | 7,614 | $266.2K | 0.27% | +7,614 | New |
| ProShare Advisors LLC | 7,480 | $261.5K | 0.00% | −1,160−13.4% | Reduced |
| Comerica Bank | 7,393 | $258.5K | 0.00% | −222−2.9% | Reduced |
| Sectoral Asset Management Inc | 7,200 | $251.7K | 0.17% | −2,240−23.7% | Reduced |
| Clearstead Advisors, LLC | 7,185 | $251.2K | 0.00% | −1,100−13.3% | Reduced |
| Tanaka Capital Management Inc | 6,892 | $241.0K | 0.55% | −7,620−52.5% | Reduced |
| Truist Financial Corp | 6,847 | $239.4K | 0.00% | −501−6.8% | Reduced |
| Everence Capital Management Inc | 6,770 | $237.0K | 0.02% | +6,770 | New |
| Silvercrest Asset Management Group LLC | 6,617 | $231.3K | 0.00% | +6,617 | New |
| Lazard Asset Management LLC | 6,557 | $228.0K | 0.00% | −16,366−71.4% | Reduced |
| KBC Group NV | 6,484 | $227.0K | 0.00% | +2,676+70.3% | Added |
| EntryPoint Capital, LLC | 6,382 | $223.1K | 0.09% | +6,382 | New |
| Gotham Asset Management, LLC | 6,260 | $218.8K | 0.00% | −20.0% | Reduced |
| Castle Rock Wealth Management, LLC | 6,972 | $216.4K | 0.05% | 00.0% | Unchanged |
| M&T Bank Corp | 6,096 | $213.6K | 0.00% | −2,800−31.5% | Reduced |
| Advisors Asset Management, Inc. | 6,070 | $212.2K | 0.00% | −70−1.1% | Reduced |
| Quarry LP | 6,000 | $209.8K | 0.04% | +6,000 | New |
| Vontobel Holding Ltd. | 5,865 | $205.0K | 0.00% | +363+6.6% | Added |
| Stevens Capital Management LP | 5,860 | $205.0K | 0.08% | +5,860 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 5,654 | $196.8K | 0.00% | +69+1.2% | Added |
| Caption Management, LLC | 5,417 | $189.4K | 0.01% | −21,183−79.6% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 5,262 | $189.0K | 0.00% | −26−0.5% | Reduced |
| Sandia Investment Management LP | 5,000 | $174.8K | 0.33% | 00.0% | Unchanged |
| US Bancorp | 4,220 | $147.5K | 0.00% | −1,510−26.4% | Reduced |
| Ci Investments Inc. | 4,090 | $143.0K | 0.00% | +710+21.0% | Added |
| GF Fund Management Co. Ltd. | 3,315 | $115.9K | 0.00% | +3,315 | New |
| Steward Partners Investment Advisory, LLC | 3,074 | $107.5K | 0.00% | +1,019+49.6% | Added |
| Venturi Wealth Management, LLC | 3,061 | $107.0K | 0.01% | +3,061 | New |
| Sterling Capital Management LLC | 3,010 | $105.2K | 0.00% | −35−1.1% | Reduced |
| Advisor Group Holdings, Inc. | 3,986 | $99.0K | 0.00% | −12,386−75.7% | Reduced |
| Corebridge Financial, Inc. | 2,759 | $96.5K | 0.00% | −117−4.1% | Reduced |
| CWM, LLC | 2,051 | $72.0K | 0.00% | +310+17.8% | Added |
| GWM Advisors LLC | 1,820 | $63.6K | 0.00% | 00.0% | Unchanged |
| Raiffeisen Bank International AG | 1,754 | $62.3K | 0.00% | +1,754 | New |
| Twin Lakes Capital Management, LLC | 1,500 | $52.4K | 0.03% | 00.0% | Unchanged |
| IFP Advisors, Inc | 1,150 | $49.1K | 0.00% | −76−6.2% | Reduced |
| Horizon Investments, LLC | 1,174 | $41.0K | 0.00% | +73+6.6% | Added |
| Itau Unibanco Holding S.A. | 1,151 | $40.2K | 0.00% | +70+6.5% | Added |
| CIBC Private Wealth Group, LLC | 1,125 | $38.4K | 0.00% | −1,300−53.6% | Reduced |
| Quadrant Capital Group LLC | 1,086 | $38.0K | 0.00% | +216+24.8% | Added |
| Lindbrook Capital, LLC | 1,036 | $36.2K | 0.00% | +671+183.8% | Added |
| Sunbelt Securities, Inc. | 1,014 | $35.4K | 0.00% | 00.0% | Unchanged |
| Manchester Capital Management LLC | 1,005 | $35.1K | 0.00% | +160+18.9% | Added |
| Parallel Advisors, LLC | 959 | $33.5K | 0.00% | −69−6.7% | Reduced |
| Huntington National Bank | 951 | $33.2K | 0.00% | +627+193.5% | Added |
| Signaturefd, LLC | 949 | $33.2K | 0.00% | +584+160.0% | Added |
| Harbour Investments, Inc. | 900 | $31.5K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 855 | $27.8K | 0.00% | +25+3.0% | Added |
| GAMMA Investing LLC | 746 | $26.1K | 0.00% | +82+12.3% | Added |
| Farther Finance Advisors, LLC | 651 | $22.8K | 0.00% | +30+4.8% | Added |
| Mather Group, LLC. | 651 | $22.8K | 0.00% | +135+26.2% | Added |
| Laurel Wealth Advisors LLC | 600 | $21.0K | 0.00% | 00.0% | Unchanged |
| Archer Investment Corp | 600 | $21.0K | 0.01% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 541 | $19.0K | 0.00% | 00.0% | Unchanged |
| Danske Bank A/S | 500 | $17.5K | 0.00% | −1,600−76.2% | Reduced |
| Riverview Trust Co | 476 | $16.6K | 0.02% | −11−2.3% | Reduced |
| EverSource Wealth Advisors, LLC | 468 | $16.4K | 0.00% | +230+96.6% | Added |
| Parkside Financial Bank & Trust | 418 | $14.6K | 0.00% | +128+44.1% | Added |
| ORG Wealth Partners, LLC | 400 | $14.0K | 0.00% | 00.0% | Unchanged |
| Global Trust Asset Management, LLC | 399 | $13.9K | 0.01% | −75−15.8% | Reduced |
| AlphaMark Advisors, LLC | 369 | $13.0K | 0.01% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 328 | $11.5K | 0.00% | −99−23.2% | Reduced |
| Elequin Capital LP | 325 | $11.4K | 0.00% | −112−25.6% | Reduced |
| Global X Japan Co., Ltd. | 297 | $10.4K | 0.00% | +62+26.4% | Added |
| Storebrand Asset Management AS | 271 | $9.47K | 0.00% | 00.0% | Unchanged |
| Union Bancaire Privee, UBP SA | 265 | $9.25K | 0.00% | +265 | New |
| MAI Capital Management | 260 | $9.09K | 0.00% | +260 | New |
| Ronald Blue Trust, Inc. | 259 | $9.05K | 0.00% | −27−9.4% | Reduced |
| Covestor Ltd | 246 | $9.00K | 0.01% | −4−1.6% | Reduced |
| SBI Securities Co., Ltd. | 256 | $8.95K | 0.00% | +256 | New |
| Riggs Asset Managment Co. Inc. | 250 | $8.73K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 233 | $8.15K | 0.00% | +130+126.2% | Added |
| Newbridge Financial Services Group, Inc. | 200 | $6.99K | 0.00% | +200 | New |
| Tidemark, LLC | 200 | $6.99K | 0.00% | +200 | New |