Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 305
- −10 vs. Q1 2023
- Shares held
- 136.5M
- +5.40M (+4.1%) vs. Q1 2023
- Total value
- $5.60B
- +$907.9M (+19.3%) vs. Q1 2023
- New holders
- 33
- 97 more added
- Sold out
- 43
- 111 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,463,816 | $880.7M | 0.07% | +27,482+0.1% | Added |
| Vanguard Group Inc | 14,523,266 | $595.9M | 0.01% | +547,476+3.9% | Added |
| T. Rowe Price Investment Management, Inc. | 13,083,727 | $536.8M | 0.37% | +19,680+0.2% | Added |
| Bellevue Group AG | 9,380,300 | $384.9M | 5.49% | −131,600−1.4% | Reduced |
| BlackRock Inc. | 9,136,174 | $374.9M | 0.01% | +153,928+1.7% | Added |
| Clearbridge Investments, LLC | 5,187,204 | $212.8M | 0.19% | −204,377−3.8% | Reduced |
| State Street Corp | 3,974,453 | $163.1M | 0.01% | −93,881−2.3% | Reduced |
| Price T Rowe Associates Inc | 3,835,867 | $157.4M | 0.02% | −99,084−2.5% | Reduced |
| Tweedy, Browne Co LLC | 3,540,858 | $145.3M | 7.63% | −1880.0% | Reduced |
| Pictet Asset Management SA | 3,095,670 | $127.0M | 0.15% | +1,982,628+178.1% | Added |
| BVF Inc | 2,846,015 | $116.8M | 3.25% | +285,254+11.1% | Added |
| Deep Track Capital, LP | 2,834,069 | $116.3M | 5.43% | 00.0% | Unchanged |
| Camber Capital Management LP | 2,500,000 | $102.6M | 3.34% | +575,000+29.9% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,422,631 | $99.4M | 0.66% | −214,561−8.1% | Reduced |
| OrbiMed Advisors LLC | 2,169,500 | $89.0M | 1.73% | +45,000+2.1% | Added |
| Geode Capital Management, LLC | 2,156,868 | $88.5M | 0.01% | +86,918+4.2% | Added |
| Macquarie Group Ltd | 1,498,882 | $61.5M | 0.07% | +4,979+0.3% | Added |
| First Trust Advisors LP | 1,323,032 | $54.3M | 0.06% | −315,911−19.3% | Reduced |
| Charles Schwab Investment Management Inc | 1,199,220 | $49.2M | 0.01% | +12,827+1.1% | Added |
| Morgan Stanley | 1,128,888 | $46.3M | 0.00% | +125,879+12.6% | Added |
| JPMorgan Chase & Co | 1,067,723 | $43.8M | 0.01% | +10,328+1.0% | Added |
| Woodline Partners LP | 1,041,932 | $42.8M | 0.51% | +1,041,932 | New |
| Norges Bank | 1,012,618 | $41.5M | 0.01% | −120,073−10.6% | Reduced |
| Thrivent Financial for Lutherans | 987,450 | $40.5M | 0.09% | +54,910+5.9% | Added |
| Swedbank AB | 936,748 | $38.4M | 0.07% | −24,926−2.6% | Reduced |
| Wellington Management Group LLP | 914,723 | $37.5M | 0.01% | +914,723 | New |
| Capital World Investors | 839,463 | $34.4M | 0.01% | +839,463 | New |
| TD Asset Management Inc | 785,208 | $32.2M | 0.04% | −32,100−3.9% | Reduced |
| Citadel Advisors LLC | 721,778 | $29.6M | 0.03% | +570,255+376.3% | Added |
| Northern Trust Corp | 671,078 | $27.5M | 0.01% | +12,612+1.9% | Added |
| Wells Fargo & Company | 612,891 | $25.1M | 0.01% | −13,259−2.1% | Reduced |
| Royal Bank of Canada | 577,138 | $23.7M | 0.01% | +81,181+16.4% | Added |
| Bank of New York Mellon Corp | 557,754 | $22.9M | 0.00% | −8,341−1.5% | Reduced |
| Jacobs Levy Equity Management, Inc | 549,558 | $22.5M | 0.13% | +12,870+2.4% | Added |
| Barclays PLC | 542,232 | $22.2M | 0.01% | +83,415+18.2% | Added |
| AXA S.A. | 525,164 | $21.5M | 0.07% | +4,296+0.8% | Added |
| Candriam Luxembourg S.C.A. | 524,067 | $21.5M | 0.16% | +78,870+17.7% | Added |
| Pinnacle Associates Ltd | 478,204 | $19.6M | 0.34% | −12,451−2.5% | Reduced |
| Bank of America Corp | 459,319 | $18.8M | 0.00% | −173,325−27.4% | Reduced |
| Nomura Holdings Inc | 435,380 | $17.9M | 0.18% | +34,057+8.5% | Added |
| Millennium Management LLC | 418,913 | $17.2M | 0.02% | +373,550+823.5% | Added |
| Renaissance Technologies LLC | 370,500 | $15.2M | 0.02% | −265,814−41.8% | Reduced |
| Alliancebernstein L.P. | 346,538 | $14.2M | 0.01% | +297,938+613.0% | Added |
| Two Sigma Advisers, LP | 344,211 | $14.1M | 0.04% | −1,600−0.5% | Reduced |
| Nuveen Asset Management, LLC | 341,451 | $14.0M | 0.00% | +27,586+8.8% | Added |
| Baillie Gifford & Co | 330,346 | $13.6M | 0.01% | −2,313−0.7% | Reduced |
| Liontrust Investment Partners LLP | 321,574 | $13.2M | 0.19% | −16,027−4.7% | Reduced |
| Altrinsic Global Advisors LLC | 307,990 | $12.6M | 0.48% | −14,291−4.4% | Reduced |
| CI Private Wealth, LLC | 305,468 | $12.5M | 0.03% | +182+0.1% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 296,132 | $12.2M | 0.01% | −1,337−0.4% | Reduced |
| Nikko Asset Management Americas, Inc. | 296,132 | $12.1M | 0.13% | −1,337−0.4% | Reduced |
| Swiss National Bank | 280,100 | $11.5M | 0.01% | +4,200+1.5% | Added |
| Hudson Bay Capital Management LP | 275,000 | $11.3M | 0.11% | −30,800−10.1% | Reduced |
| Stifel Financial Corp | 268,981 | $11.0M | 0.02% | −850−0.3% | Reduced |
| Manufacturers Life Insurance Company, The | 263,559 | $10.8M | 0.01% | +190,947+263.0% | Added |
| California Public Employees Retirement System | 257,474 | $10.6M | 0.01% | −24,852−8.8% | Reduced |
| Credit Suisse AG | 244,982 | $10.1M | 0.01% | +2,911+1.2% | Added |
| Eversept Partners, LP | 241,572 | $9.91M | 1.05% | −61,797−20.4% | Reduced |
| Kennedy Capital Management, Inc. | 230,261 | $9.45M | 0.22% | +47,836+26.2% | Added |
| Privium Fund Management B.V. | 226,493 | $9.31M | 2.68% | +43,720+23.9% | Added |
| Bank of Montreal | 223,131 | $9.28M | 0.01% | +9,200+4.3% | Added |
| Two Sigma Investments, LP | 213,372 | $8.75M | 0.02% | +190,292+824.5% | Added |
| Sicart Associates LLC | 204,947 | $8.41M | 3.27% | −5,751−2.7% | Reduced |
| Point72 Asset Management, L.P. | 204,400 | $8.39M | 0.03% | +108,515+113.2% | Added |
| Rafferty Asset Management, LLC | 204,388 | $8.39M | 0.05% | +501+0.2% | Added |
| Tang Capital Management LLC | 200,000 | $8.21M | 1.21% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 198,508 | $8.14M | 0.04% | −80,250−28.8% | Reduced |
| Rhumbline Advisers | 197,333 | $8.10M | 0.01% | +20,648+11.7% | Added |
| D. E. Shaw & Co., Inc. | 196,213 | $8.05M | 0.01% | +109,562+126.4% | Added |
| Raymond James & Associates | 191,884 | $7.87M | 0.01% | −9,070−4.5% | Reduced |
| Goldman Sachs Group Inc | 188,372 | $7.73M | 0.00% | −233,726−55.4% | Reduced |
| Dimensional Fund Advisors LP | 182,714 | $7.50M | 0.00% | −260,171−58.7% | Reduced |
| Susquehanna International Group, LLP | 167,516 | $6.87M | 0.01% | +111,596+199.6% | Added |
| Tocqueville Asset Management L.P. | 162,480 | $6.67M | 0.12% | 00.0% | Unchanged |
| California State Teachers Retirement System | 160,998 | $6.61M | 0.01% | −4,182−2.5% | Reduced |
| Sector Gamma AS | 160,401 | $6.58M | 1.47% | +13,960+9.5% | Added |
| UBS Asset Management Americas Inc | 176,733 | $6.32M | 0.00% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 153,052 | $6.28M | 1.09% | +1,891+1.3% | Added |
| State Board of Administration of Florida Retirement System | 150,768 | $6.19M | 0.01% | −4,377−2.8% | Reduced |
| BLB&B Advisors, LLC | 150,300 | $6.17M | 0.43% | +1,340+0.9% | Added |
| Sonora Investment Management Group, LLC | 150,205 | $6.16M | 0.52% | −2,628−1.7% | Reduced |
| Peregrine Capital Management LLC | 149,198 | $6.12M | 0.17% | −490.0% | Reduced |
| New York State Common Retirement Fund | 135,556 | $5.56M | 0.01% | +1,556+1.2% | Added |
| Legal & General Group Plc | 133,343 | $5.47M | 0.00% | −7,375−5.2% | Reduced |
| Invesco Ltd. | 129,718 | $5.32M | 0.00% | −186,002−58.9% | Reduced |
| Balyasny Asset Management LLC | 125,850 | $5.16M | 0.01% | −77,616−38.1% | Reduced |
| Amundi | 120,846 | $4.96M | 0.00% | +115,478+2,151.2% | Added |
| Russell Investments Group, Ltd. | 113,330 | $4.65M | 0.01% | +9,854+9.5% | Added |
| BNP Paribas Arbitrage, SA | 110,516 | $4.53M | 0.01% | +11,401+11.5% | Added |
| Eventide Asset Management, LLC | 110,000 | $4.51M | 0.08% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 109,310 | $4.48M | 0.01% | −5,941−5.2% | Reduced |
| Jane Street Group, LLC | 108,324 | $4.44M | 0.01% | +4,423+4.3% | Added |
| Jump Financial, LLC | 105,768 | $4.34M | 0.16% | +105,768 | New |
| Trexquant Investment LP | 104,625 | $4.29M | 0.11% | +72,013+220.8% | Added |
| Public Sector Pension Investment Board | 98,000 | $4.02M | 0.03% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 93,000 | $3.82M | 0.08% | +93,000 | New |
| UBS Group AG | 92,825 | $3.81M | 0.00% | −8,121−8.0% | Reduced |
| DekaBank Deutsche Girozentrale | 90,000 | $3.71M | 0.01% | −75,000−45.5% | Reduced |
| Commerce Bank | 88,282 | $3.62M | 0.03% | +80,736+1,069.9% | Added |
| Agf Management Ltd | 87,867 | $3.61M | 0.03% | −6,758−7.1% | Reduced |