Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 350
- −1 vs. Q2 2022
- Shares held
- 126.4M
- +1.80M (+1.4%) vs. Q2 2022
- Total value
- $5.59B
- +$976.9M (+21.2%) vs. Q2 2022
- New holders
- 50
- 97 more added
- Sold out
- 51
- 130 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,291,159 | $941.7M | 0.10% | +21,599+0.1% | Added |
| Vanguard Group Inc | 12,806,023 | $566.4M | 0.02% | +605,747+5.0% | Added |
| T. Rowe Price Investment Management, Inc. | 11,156,695 | $493.5M | 0.39% | +11,156,695 | New |
| Bellevue Group AG | 9,463,400 | $418.6M | 6.01% | −313,128−3.2% | Reduced |
| BlackRock Inc. | 8,936,062 | $395.2M | 0.01% | +104,672+1.2% | Added |
| Clearbridge Investments, LLC | 5,773,892 | $255.4M | 0.26% | −231,926−3.9% | Reduced |
| Price T Rowe Associates Inc | 4,797,132 | $212.2M | 0.03% | −10,258,914−68.1% | Reduced |
| State Street Corp | 3,760,955 | $166.3M | 0.01% | −441,919−10.5% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 3,713,107 | $164.2M | 1.14% | −988,190−21.0% | Reduced |
| BVF Inc | 2,872,953 | $127.1M | 5.25% | +1,596,379+125.1% | Added |
| Tweedy, Browne Co LLC | 2,722,988 | $120.4M | 5.30% | −3,790−0.1% | Reduced |
| First Trust Advisors LP | 2,077,260 | $91.9M | 0.12% | +481,205+30.1% | Added |
| Camber Capital Management LP | 1,925,000 | $85.1M | 2.85% | −775,000−28.7% | Reduced |
| Geode Capital Management, LLC | 1,901,143 | $84.1M | 0.01% | +36,010+1.9% | Added |
| Goldman Sachs Group Inc | 1,290,565 | $57.1M | 0.02% | +248,741+23.9% | Added |
| Charles Schwab Investment Management Inc | 1,202,346 | $53.2M | 0.02% | +48,321+4.2% | Added |
| Norges Bank | 1,190,751 | $52.7M | 0.01% | +72,410+6.5% | Added |
| Swedbank AB | 1,021,429 | $45.2M | 0.11% | −852−0.1% | Reduced |
| JPMorgan Chase & Co | 928,752 | $41.1M | 0.01% | −110,818−10.7% | Reduced |
| Thrivent Financial for Lutherans | 908,479 | $40.2M | 0.11% | −368,304−28.8% | Reduced |
| Renaissance Technologies LLC | 867,714 | $38.4M | 0.05% | +252,900+41.1% | Added |
| Macquarie Group Ltd | 834,041 | $37.0M | 0.05% | +800,773+2,407.0% | Added |
| TD Asset Management Inc | 804,083 | $35.6M | 0.04% | +419+0.1% | Added |
| OrbiMed Advisors LLC | 768,900 | $34.0M | 0.68% | +315,500+69.6% | Added |
| Morgan Stanley | 696,538 | $30.8M | 0.00% | −41,439−5.6% | Reduced |
| Wells Fargo & Company | 689,872 | $30.5M | 0.01% | −34,123−4.7% | Reduced |
| Two Sigma Advisers, LP | 657,511 | $29.1M | 0.08% | −48,300−6.8% | Reduced |
| Northern Trust Corp | 623,640 | $27.6M | 0.01% | −1,832−0.3% | Reduced |
| Bank of New York Mellon Corp | 579,413 | $25.6M | 0.01% | −85,903−12.9% | Reduced |
| Dimensional Fund Advisors LP | 560,928 | $24.8M | 0.01% | −24,120−4.1% | Reduced |
| Bank of America Corp | 559,956 | $24.8M | 0.00% | −48,596−8.0% | Reduced |
| Jacobs Levy Equity Management, Inc | 511,975 | $22.6M | 0.18% | −104,791−17.0% | Reduced |
| Barclays PLC | 504,488 | $22.3M | 0.02% | +149,909+42.3% | Added |
| Pinnacle Associates Ltd | 500,890 | $22.2M | 0.51% | −14,969−2.9% | Reduced |
| Assenagon Asset Management S.A. | 452,760 | $20.0M | 0.09% | +112,044+32.9% | Added |
| Candriam Luxembourg S.C.A. | 451,351 | $20.0M | 0.14% | −119,341−20.9% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 437,176 | $19.3M | 0.02% | −30,940−6.6% | Reduced |
| Royal Bank of Canada | 436,824 | $19.3M | 0.01% | +8,401+2.0% | Added |
| Citadel Advisors LLC | 418,232 | $18.5M | 0.02% | −61,911−12.9% | Reduced |
| Redmile Group, LLC | 407,659 | $18.0M | 0.70% | +407,659 | New |
| Woodline Partners LP | 406,483 | $18.0M | 0.26% | +276,575+212.9% | Added |
| Nomura Holdings Inc | 387,908 | $17.1M | 0.17% | +11,931+3.2% | Added |
| Nikko Asset Management Americas, Inc. | 437,176 | $16.0M | 0.20% | −30,940−6.6% | Reduced |
| Bank of Montreal | 323,529 | $15.1M | 0.01% | +91,537+39.5% | Added |
| Nuveen Asset Management, LLC | 339,284 | $15.0M | 0.01% | −9,402−2.7% | Reduced |
| Baillie Gifford & Co | 324,842 | $14.4M | 0.01% | +13,827+4.4% | Added |
| California Public Employees Retirement System | 323,586 | $14.3M | 0.01% | +41,204+14.6% | Added |
| Swiss National Bank | 302,600 | $13.4M | 0.01% | +3,300+1.1% | Added |
| Dowling & Yahnke LLC | 302,571 | $13.4M | 0.62% | 00.0% | Unchanged |
| Stifel Financial Corp | 300,013 | $13.3M | 0.02% | −6,307−2.1% | Reduced |
| Invesco Ltd. | 295,199 | $13.1M | 0.00% | −30,786−9.4% | Reduced |
| Two Sigma Investments, LP | 292,994 | $13.0M | 0.04% | −267,037−47.7% | Reduced |
| UBS Asset Management Americas Inc | 279,624 | $12.4M | 0.01% | +73,835+35.9% | Added |
| Pictet Asset Management SA | 276,977 | $12.3M | 0.02% | +38,638+16.2% | Added |
| Sicart Associates LLC | 253,976 | $11.2M | 3.98% | −34,775−12.0% | Reduced |
| Parkman Healthcare Partners LLC | 241,945 | $10.7M | 3.04% | +67,645+38.8% | Added |
| Raymond James & Associates | 238,168 | $10.5M | 0.01% | −8,281−3.4% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 229,061 | $10.1M | 0.07% | +97,078+73.6% | Added |
| D. E. Shaw & Co., Inc. | 209,445 | $9.26M | 0.02% | +82,824+65.4% | Added |
| Schonfeld Strategic Advisors LLC | 207,672 | $9.19M | 0.08% | +77,649+59.7% | Added |
| Eversept Partners, LP | 201,833 | $8.93M | 1.06% | +115,522+133.8% | Added |
| Tang Capital Management LLC | 200,000 | $8.85M | 1.08% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 199,800 | $8.84M | 0.09% | +14,800+8.0% | Added |
| AXA S.A. | 182,356 | $8.07M | 0.03% | +23,821+15.0% | Added |
| Man Group plc | 177,597 | $7.86M | 0.04% | – | – |
| Citigroup Inc | 176,992 | $7.83M | 0.01% | +27,861+18.7% | Added |
| California State Teachers Retirement System | 165,925 | $7.34M | 0.01% | −3,489−2.1% | Reduced |
| Sector Gamma AS | 164,223 | $7.26M | 1.87% | −1,216−0.7% | Reduced |
| State Board of Administration of Florida Retirement System | 163,255 | $7.22M | 0.02% | −870−0.5% | Reduced |
| Tocqueville Asset Management L.P. | 162,394 | $7.18M | 0.15% | −211−0.1% | Reduced |
| Altrinsic Global Advisors LLC | 161,246 | $7.13M | 0.33% | −25,208−13.5% | Reduced |
| Rhumbline Advisers | 155,714 | $6.89M | 0.01% | +1,212+0.8% | Added |
| Credit Suisse AG | 154,698 | $6.84M | 0.01% | +4,977+3.3% | Added |
| Susquehanna Fundamental Investments, LLC | 153,636 | $6.79M | 0.12% | +153,636 | New |
| Rafferty Asset Management, LLC | 151,974 | $6.72M | 0.07% | +32,691+27.4% | Added |
| BLB&B Advisors, LLC | 149,070 | $6.59M | 0.55% | −180−0.1% | Reduced |
| Privium Fund Management B.V. | 148,807 | $6.59M | 2.49% | −31,300−17.4% | Reduced |
| Kennedy Capital Management, Inc. | 144,795 | $6.40M | 0.19% | +25,113+21.0% | Added |
| New York State Common Retirement Fund | 142,900 | $6.32M | 0.01% | −3,925−2.7% | Reduced |
| Fred Alger Management, LLC | 142,522 | $6.30M | 0.03% | −4,134−2.8% | Reduced |
| Natixis | 134,081 | $5.94M | 0.03% | +134,081 | New |
| BNP Paribas Arbitrage, SA | 132,740 | $5.87M | 0.01% | +12,770+10.6% | Added |
| Sonora Investment Management Group, LLC | 157,023 | $5.81M | 0.75% | +700+0.4% | Added |
| State of Wisconsin Investment Board | 129,854 | $5.74M | 0.02% | −7,379−5.4% | Reduced |
| Legal & General Group Plc | 128,453 | $5.68M | 0.00% | −35,501−21.7% | Reduced |
| DekaBank Deutsche Girozentrale | 124,776 | $5.50M | 0.02% | 00.0% | Unchanged |
| Peregrine Capital Management LLC | 123,396 | $5.46M | 0.18% | −6,828−5.2% | Reduced |
| Eventide Asset Management, LLC | 110,000 | $4.87M | 0.10% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 109,872 | $4.86M | 0.06% | −27,910−20.3% | Reduced |
| Jefferies Group LLC | 105,566 | $4.67M | 0.14% | +105,566 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 92,700 | $4.10M | 0.02% | +92,700 | New |
| Russell Investments Group, Ltd. | 92,320 | $4.08M | 0.01% | −6,914−7.0% | Reduced |
| Squarepoint Ops LLC | 92,054 | $4.07M | 0.04% | −37,886−29.2% | Reduced |
| Manufacturers Life Insurance Company, The | 89,096 | $3.94M | 0.00% | −4,118−4.4% | Reduced |
| Bard Financial Services, Inc. | 87,895 | $3.89M | 0.36% | −5,550−5.9% | Reduced |
| Tekla Capital Management LLC | 87,840 | $3.88M | 0.16% | −87,840−50.0% | Reduced |
| Jump Financial, LLC | 86,602 | $3.83M | 0.15% | −28,255−24.6% | Reduced |
| Walleye Capital LLC | 85,963 | $3.80M | 0.09% | +79,594+1,249.7% | Added |
| Davenport & Co LLC | 84,863 | $3.75M | 0.03% | +1,545+1.9% | Added |
| State of New Jersey Common Pension Fund D | 80,433 | $3.56M | 0.01% | 00.0% | Unchanged |