Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 354
- +1 vs. Q2 2024
- Shares held
- 157.5M
- +24.6M (+18.5%) vs. Q2 2024
- Total value
- $6.31B
- −$23.0M (−0.4%) vs. Q2 2024
- New holders
- 53
- 131 more added
- Sold out
- 52
- 107 more reduced
4 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 22,479,529 | $900.5M | 0.05% | +584,723+2.7% | Added |
| Vanguard Group Inc | 15,055,758 | $603.1M | 0.01% | +1,210,046+8.7% | Added |
| T. Rowe Price Investment Management, Inc. | 14,168,116 | $567.6M | 0.34% | +1,528,432+12.1% | Added |
| BlackRock, Inc. | 10,813,023 | $433.2M | 0.01% | +10,813,023 | New |
| Wellington Management Group LLP | 8,735,787 | $350.0M | 0.06% | +2,166,979+33.0% | Added |
| Bellevue Group AG | 7,874,400 | $315.4M | 5.11% | −386,034−4.7% | Reduced |
| Capital World Investors | 7,828,372 | $313.6M | 0.05% | +5,576,283+247.6% | Added |
| State Street Corp | 4,850,137 | $194.3M | 0.01% | +659,632+15.7% | Added |
| Price T Rowe Associates Inc | 4,210,172 | $168.7M | 0.02% | +275,861+7.0% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $138.4M | 6.60% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 2,668,358 | $106.9M | 0.01% | +183,814+7.4% | Added |
| OrbiMed Advisors LLC | 2,324,447 | $93.1M | 1.70% | −47,886−2.0% | Reduced |
| Artisan Partners Limited Partnership | 2,240,455 | $89.8M | 0.13% | +569,419+34.1% | Added |
| Deep Track Capital, LP | 2,200,000 | $88.1M | 2.81% | +200,000+10.0% | Added |
| Norges Bank | 2,027,161 | $81.2M | 0.01% | +1,007,820+98.9% | Added |
| Marshall Wace, LLP | 1,920,464 | $76.9M | 0.10% | +1,747,265+1,008.8% | Added |
| Macquarie Group Ltd | 1,869,806 | $74.9M | 0.08% | −3,862−0.2% | Reduced |
| Clearbridge Investments, LLC | 1,702,393 | $68.2M | 0.05% | −457,877−21.2% | Reduced |
| BVF Inc | 1,451,879 | $58.2M | 1.70% | −1,734,497−54.4% | Reduced |
| Charles Schwab Investment Management Inc | 1,443,020 | $57.8M | 0.01% | +114,914+8.7% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,384,269 | $55.5M | 0.51% | +23,244+1.7% | Added |
| Two Sigma Advisers, LP | 1,332,411 | $53.4M | 0.13% | +45,300+3.5% | Added |
| Pictet Asset Management Holding SA | 1,303,501 | $52.7M | 0.06% | −1,106,453−45.9% | Reduced |
| Morgan Stanley | 1,310,451 | $52.5M | 0.00% | +297,646+29.4% | Added |
| TD Asset Management Inc | 1,092,990 | $44.6M | 0.04% | +140,228+14.7% | Added |
| Candriam Luxembourg S.C.A. | 948,266 | $38.0M | 0.22% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 919,077 | $36.8M | 0.08% | −109,065−10.6% | Reduced |
| Invesco Ltd. | 810,301 | $32.5M | 0.01% | −158,616−16.4% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 779,721 | $31.2M | 0.08% | −1,032−0.1% | Reduced |
| Hudson Bay Capital Management LP | 766,900 | $30.7M | 0.21% | +400,900+109.5% | Added |
| Logos Global Management LP | 750,000 | $30.0M | 3.37% | +450,000+150.0% | Added |
| Northern Trust Corp | 742,904 | $29.8M | 0.00% | +24,929+3.5% | Added |
| Royal Bank of Canada | 670,149 | $26.8M | 0.01% | −8,211−1.2% | Reduced |
| Jacobs Levy Equity Management, Inc | 650,779 | $26.1M | 0.10% | +77,909+13.6% | Added |
| Barclays PLC | 637,032 | $25.5M | 0.01% | +21,358+3.5% | Added |
| Bank of New York Mellon Corp | 610,893 | $24.5M | 0.00% | +13,414+2.2% | Added |
| J. Goldman & Co LP | 609,416 | $24.4M | 1.06% | +591,914+3,382.0% | Added |
| Man Group plc | 596,263 | $23.9M | 0.07% | −37,146−5.9% | Reduced |
| Pinnacle Associates Ltd | 458,979 | $23.2M | 0.40% | +5,600+1.2% | Added |
| JPMorgan Chase & Co | 568,906 | $22.8M | 0.00% | −25,185−4.2% | Reduced |
| Bank of America Corp | 568,660 | $22.8M | 0.00% | +54,117+10.5% | Added |
| AXA S.A. | 561,243 | $22.5M | 0.07% | +96,280+20.7% | Added |
| Adage Capital Partners GP, L.L.C. | 500,000 | $20.0M | 0.04% | −300,000−37.5% | Reduced |
| EcoR1 Capital, LLC | 500,000 | $20.0M | 0.69% | +500,000 | New |
| Eversept Partners, LP | 471,355 | $18.9M | 1.45% | +14,474+3.2% | Added |
| Nomura Holdings Inc | 453,069 | $18.1M | 0.14% | −48,119−9.6% | Reduced |
| Millennium Management LLC | 430,723 | $17.3M | 0.01% | +302,508+235.9% | Added |
| Tocqueville Asset Management L.P. | 406,870 | $16.3M | 0.26% | +181,800+80.8% | Added |
| First Trust Advisors LP | 402,300 | $16.1M | 0.02% | +386,106+2,384.3% | Added |
| Citadel Advisors LLC | 401,151 | $16.1M | 0.02% | −225,882−36.0% | Reduced |
| Ghisallo Capital Management LLC | 400,000 | $16.0M | 0.79% | +400,000 | New |
| Ameriprise Financial Inc | 397,898 | $15.9M | 0.00% | +389,106+4,425.7% | Added |
| Voloridge Investment Management, LLC | 380,641 | $15.2M | 0.06% | +380,641 | New |
| Schonfeld Strategic Advisors LLC | 362,888 | $14.5M | 0.12% | −360,730−49.9% | Reduced |
| Groupama Asset Managment | 416,060 | $13.8M | 0.36% | +36,084+9.5% | Added |
| Wells Fargo & Company | 342,154 | $13.7M | 0.00% | −24,407−6.7% | Reduced |
| Manufacturers Life Insurance Company, The | 308,947 | $12.4M | 0.01% | +34,097+12.4% | Added |
| Nuveen Asset Management, LLC | 304,779 | $12.2M | 0.00% | −105,625−25.7% | Reduced |
| Standard Life Aberdeen plc | 303,274 | $12.1M | 0.02% | +56,357+22.8% | Added |
| C WorldWide Group Holding A/S | 300,000 | $12.0M | 0.12% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 285,697 | $11.4M | 0.00% | −34,593−10.8% | Reduced |
| Swiss National Bank | 256,600 | $10.3M | 0.01% | −1,400−0.5% | Reduced |
| Great Point Partners LLC | 255,000 | $10.2M | 3.08% | −75,000−22.7% | Reduced |
| Privium Fund Management B.V. | 250,744 | $10.0M | 2.50% | +3,477+1.4% | Added |
| Siren, L.L.C. | 250,000 | $10.0M | 0.50% | +250,000 | New |
| CI Private Wealth, LLC | 237,076 | $9.50M | 0.01% | −30,961−11.6% | Reduced |
| Goldman Sachs Group Inc | 235,710 | $9.44M | 0.00% | −92,595−28.2% | Reduced |
| Twinbeech Capital LP | 235,477 | $9.43M | 0.18% | +235,477 | New |
| Driehaus Capital Management LLC | 229,969 | $9.21M | 0.08% | +229,969 | New |
| Baker Bros. Advisors LP | 223,470 | $8.95M | 0.09% | +223,470 | New |
| Orion Investment Co | 218,525 | $8.75M | 3.42% | −450.0% | Reduced |
| Bank of Montreal | 213,883 | $8.74M | 0.00% | −6,635−3.0% | Reduced |
| California Public Employees Retirement System | 211,756 | $8.48M | 0.01% | +15,272+7.8% | Added |
| Sector Gamma AS | 210,842 | $8.45M | 2.56% | +40,842+24.0% | Added |
| International Assets Investment Management, LLC | 328,772 | $8.21M | 0.04% | +319,065+3,287.0% | Added |
| New York State Common Retirement Fund | 198,759 | $7.96M | 0.01% | −16,957−7.9% | Reduced |
| Rafferty Asset Management, LLC | 198,759 | $7.96M | 0.03% | +29,903+17.7% | Added |
| Rhumbline Advisers | 196,942 | $7.89M | 0.01% | +18,853+10.6% | Added |
| Nikko Asset Management Americas, Inc. | 196,114 | $7.86M | 0.09% | −3,117−1.6% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 196,114 | $7.86M | 0.01% | −3,117−1.6% | Reduced |
| Rhenman & Partners Asset Management AB | 195,000 | $7.81M | 0.63% | +65,000+50.0% | Added |
| Sicart Associates LLC | 191,523 | $7.67M | 2.69% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 190,514 | $7.63M | 0.01% | −59,000−23.6% | Reduced |
| SEI Investments Co | 189,837 | $7.60M | 0.01% | +57,526+43.5% | Added |
| Altrinsic Global Advisors LLC | 182,734 | $7.32M | 0.31% | −5,097−2.7% | Reduced |
| Stifel Financial Corp | 182,505 | $7.31M | 0.01% | −33,635−15.6% | Reduced |
| Jane Street Group, LLC | 176,560 | $7.07M | 0.01% | −2,686−1.5% | Reduced |
| BNP Paribas Arbitrage, SA | 175,328 | $7.02M | 0.01% | −10,616−5.7% | Reduced |
| Alyeska Investment Group, L.P. | 168,951 | $6.77M | 0.03% | +168,951 | New |
| UBS Group AG | 167,880 | $6.73M | 0.00% | +15,208+10.0% | Added |
| Kennedy Capital Management, Inc. | 162,076 | $6.49M | 0.14% | −92,267−36.3% | Reduced |
| Legal & General Group Plc | 157,287 | $6.30M | 0.00% | +9,643+6.5% | Added |
| Sonora Investment Management Group, LLC | 153,175 | $6.14M | 0.45% | +2,361+1.6% | Added |
| BLB&B Advisors, LLC | 152,250 | $6.10M | 0.31% | −1,500−1.0% | Reduced |
| State Board of Administration of Florida Retirement System | 151,055 | $6.05M | 0.01% | 00.0% | Unchanged |
| Tang Capital Management LLC | 150,000 | $6.01M | 0.43% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 145,091 | $5.81M | 0.01% | −45,690−23.9% | Reduced |
| Peregrine Capital Management LLC | 131,630 | $5.27M | 0.16% | −394−0.3% | Reduced |
| Trexquant Investment LP | 130,858 | $5.24M | 0.07% | +100,772+334.9% | Added |
| Swedbank AB | 129,373 | $5.18M | 0.01% | 00.0% | Unchanged |