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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 530 institutions reported holding it in 13F filings for Q2 2026, worth $15.2B in total; ARK Invest is the only superinvestor holding it.

Key figures

Insider buysLast 90 days, $1.06M in total
1
Insider sellsLast 90 days, $6.35M in total
7
13F holdersQ2 2026, +20 vs. previous quarter
530
13F valueReported value at the end of Q2 2026
$15.2B
Superinvestors holdingAt the end of Q2 2026
1

Price chart

Superinvestors holding IONS, Q2 2026

1 superinvestor reports holding Ionis Pharmaceuticals Inc on Form 13F. Percentages are the stock's share of each portfolio.

Go to the superinvestors tab

ARK Invest

Cathie Wood

0.2%

Ionis Pharmaceuticals Inc's share of the portfolio

Shares
300,770
Value
$23.8M

Latest insider trades

Open-market purchases and sales by Ionis Pharmaceuticals Inc insiders from Form 4, newest first.

See all insider trades
Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 31, 2026 (view filing)4:42 PM ETJul 30-311 dayHayden Michael RDirectorPPurchase+20.0K$52.94+$1.06M+500.0%24.0K after2 lots
Jul 9, 2026 (view filing)7:26 PM ETJul 72 daysBennett C FrankEVP, Chief Scientific OfficerSSale−5.54K$83.58−$462.7K−6.9%75.0K after10b5-1
Jul 9, 2026 (view filing)7:26 PM ETJul 72 daysBennett C FrankEVP, Chief Scientific OfficerSSale−15.0K$85.46−$1.28M−100.0%0 after10b5-1
Jul 9, 2026 (view filing)6:07 PM ETJul 72 daysDiaz Allene M.DirectorSSale−10.1K$85.42−$863.6K−72.6%3.81K after10b5-1
Jul 9, 2026 (view filing)6:07 PM ETJul 72 daysKordasiewicz Holly B.EVP, Chief Development OfficerSSale−362$84.30−$30.5K−1.6%22.1K after10b5-1
Jul 6, 2026 (view filing)6:49 PM ETJul 15 daysKlein Joseph IIIDirectorSSale−11.5K$79.04−$910.4K−51.1%11.0K after2 lots10b5-1
Jun 30, 2026 (view filing)Jun 264 daysBaroldi JosephEVP, Chief Business OfficerSSale−5.63K$80.16−$451.7K−54.7%4.67K after10b5-1
Jun 30, 2026 (view filing)Jun 264 daysO'Neil Patrick R.EVP CLO & General CounselSSale−3.07K$80.00−$245.5K−4.8%61.5K after10b5-1
Jun 30, 2026 (view filing)Jun 264 daysSchneider EugeneEVP, Chf Clinical Develop OfcrSSale−26.0K$81.05−$2.11M−25.2%77.1K after10b5-1
Jun 26, 2026 (view filing)Jun 24-262 daysMonia Brett PChief Executive OfficerSSale−85.6K$79.70−$6.83M−25.9%245.6K after3 lots10b5-1

Top 10 13F holders, Q2 2026

The largest institutional positions in Ionis Pharmaceuticals Inc at the end of Q2 2026; share changes are against Q1 2026.

See all 530 holders
Institutions holding IONS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC24,631,956$1.96B0.09%+75,319+0.3%Added
Capital World Investors21,669,226$1.72B0.20%+482,857+2.3%Added
BlackRock, Inc.10,704,660$866.5M0.01%+262,184+2.5%Added
Wellington Management Group LLP7,651,415$624.6M0.11%+1,259,599+19.7%Added
Vanguard Portfolio Management LLC7,859,529$623.2M0.03%+50,627+0.6%Added
Vanguard Capital Management LLC7,211,497$571.8M0.01%+93,167+1.3%Added
Two Sigma Investments, LP6,252,342$495.7M0.37%+394,713+6.7%Added
Royal Bank of Canada6,182,479$490.4M0.08%+2,380,664+62.6%Added
State Street Corp4,334,848$367.1M0.01%+339,284+8.5%Added
T. Rowe Price Investment Management, Inc.3,959,372$313.9M0.21%−2,199,655−35.7%Reduced