Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 357
- −1 vs. Q1 2024
- Shares held
- 143.3M
- +1.29M (+0.9%) vs. Q1 2024
- Total value
- $6.83B
- +$666.0M (+10.8%) vs. Q1 2024
- New holders
- 52
- 120 more added
- Sold out
- 53
- 132 more reduced
3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,894,806 | $1.04B | 0.07% | +32,071+0.1% | Added |
| Vanguard Group Inc | 13,845,712 | $659.9M | 0.01% | +415,256+3.1% | Added |
| T. Rowe Price Investment Management, Inc. | 12,639,684 | $602.4M | 0.38% | −677,428−5.1% | Reduced |
| BlackRock Inc. | 10,321,030 | $491.9M | 0.01% | +549,139+5.6% | Added |
| Bellevue Group AG | 8,260,434 | $393.7M | 6.40% | −39,080−0.5% | Reduced |
| Wellington Management Group LLP | 6,568,808 | $313.1M | 0.06% | +873,109+15.3% | Added |
| State Street Corp | 4,190,505 | $199.7M | 0.01% | +34,841+0.8% | Added |
| Price T Rowe Associates Inc | 3,934,311 | $187.5M | 0.02% | +412,108+11.7% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $164.6M | 7.57% | 00.0% | Unchanged |
| BVF Inc | 3,186,376 | $151.9M | 4.26% | +757,763+31.2% | Added |
| Geode Capital Management, LLC | 2,484,544 | $118.4M | 0.01% | +120,288+5.1% | Added |
| Pictet Asset Management Holding SA | 2,409,954 | $114.9M | 0.13% | −1,329,803−35.6% | Reduced |
| OrbiMed Advisors LLC | 2,372,333 | $113.1M | 2.41% | +359,300+17.8% | Added |
| Capital World Investors | 2,252,089 | $107.3M | 0.02% | +1,412,626+168.3% | Added |
| Clearbridge Investments, LLC | 2,160,270 | $103.0M | 0.08% | −2,305,921−51.6% | Reduced |
| Deep Track Capital, LP | 2,000,000 | $95.3M | 2.85% | +626,525+45.6% | Added |
| Macquarie Group Ltd | 1,873,668 | $89.3M | 0.10% | −1,326,910−41.5% | Reduced |
| Artisan Partners Limited Partnership | 1,671,036 | $79.6M | 0.12% | +1,254,307+301.0% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,361,025 | $64.9M | 0.58% | −38,827−2.8% | Reduced |
| Charles Schwab Investment Management Inc | 1,328,106 | $63.3M | 0.01% | +26,738+2.1% | Added |
| Two Sigma Advisers, LP | 1,287,111 | $61.3M | 0.14% | +247,000+23.7% | Added |
| Balyasny Asset Management LLC | 1,077,321 | $51.3M | 0.13% | +1,077,321 | New |
| Two Sigma Investments, LP | 1,028,142 | $49.0M | 0.12% | −55,737−5.1% | Reduced |
| Norges Bank | 1,019,341 | $48.6M | 0.01% | −217,657−17.6% | Reduced |
| Morgan Stanley | 1,012,805 | $48.3M | 0.00% | −150,793−13.0% | Reduced |
| Invesco Ltd. | 968,917 | $46.2M | 0.01% | +526,030+118.8% | Added |
| TD Asset Management Inc | 952,762 | $45.4M | 0.04% | +54,400+6.1% | Added |
| Candriam Luxembourg S.C.A. | 948,266 | $45.2M | 0.27% | +36,369+4.0% | Added |
| Adage Capital Partners GP, L.L.C. | 800,000 | $38.1M | 0.07% | −200,000−20.0% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 780,753 | $37.2M | 0.10% | +2,160+0.3% | Added |
| Schonfeld Strategic Advisors LLC | 723,618 | $34.5M | 0.27% | +552,758+323.5% | Added |
| Northern Trust Corp | 717,975 | $34.2M | 0.01% | +25,728+3.7% | Added |
| Royal Bank of Canada | 678,360 | $32.3M | 0.01% | −53,877−7.4% | Reduced |
| Man Group plc | 633,409 | $30.2M | 0.08% | +380,188+150.1% | Added |
| Citadel Advisors LLC | 627,033 | $29.9M | 0.03% | +549,003+703.6% | Added |
| Barclays PLC | 615,674 | $29.3M | 0.01% | +38,287+6.6% | Added |
| Bank of New York Mellon Corp | 597,479 | $28.5M | 0.01% | +13,890+2.4% | Added |
| JPMorgan Chase & Co | 594,091 | $28.3M | 0.00% | −36,888−5.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 572,870 | $27.3M | 0.11% | +1,107+0.2% | Added |
| Bank of America Corp | 514,543 | $24.5M | 0.00% | −91,755−15.1% | Reduced |
| Nomura Holdings Inc | 501,188 | $23.9M | 0.15% | +30,351+6.4% | Added |
| AXA S.A. | 464,963 | $22.2M | 0.07% | +1480.0% | Added |
| Eversept Partners, LP | 456,881 | $21.8M | 1.67% | +80,443+21.4% | Added |
| Pinnacle Associates Ltd | 453,379 | $21.6M | 0.34% | −6,379−1.4% | Reduced |
| Squarepoint Ops LLC | 436,818 | $20.8M | 0.08% | −308,355−41.4% | Reduced |
| Nuveen Asset Management, LLC | 410,404 | $19.6M | 0.01% | −12,626−3.0% | Reduced |
| Groupama Asset Managment | 379,976 | $18.1M | 0.37% | +122,108+47.4% | Added |
| Wells Fargo & Company | 366,561 | $17.5M | 0.00% | −217,597−37.2% | Reduced |
| Hudson Bay Capital Management LP | 366,000 | $17.4M | 0.13% | +30,500+9.1% | Added |
| Great Point Partners LLC | 330,000 | $15.7M | 3.01% | +330,000 | New |
| Goldman Sachs Group Inc | 328,305 | $15.6M | 0.00% | +127,925+63.8% | Added |
| UBS Asset Management Americas Inc | 320,290 | $15.3M | 0.00% | +133,963+71.9% | Added |
| C WorldWide Group Holding A/S | 300,000 | $14.3M | 0.15% | 00.0% | Unchanged |
| Logos Global Management LP | 300,000 | $14.3M | 1.65% | +300,000 | New |
| Manufacturers Life Insurance Company, The | 274,850 | $13.1M | 0.01% | +29,783+12.2% | Added |
| CI Private Wealth, LLC | 268,037 | $12.8M | 0.02% | +746+0.3% | Added |
| Baillie Gifford & Co | 260,254 | $12.4M | 0.01% | −35,429−12.0% | Reduced |
| Swiss National Bank | 258,000 | $12.3M | 0.01% | +3,100+1.2% | Added |
| Kennedy Capital Management, Inc. | 254,343 | $12.1M | 0.26% | +4,816+1.9% | Added |
| Integral Health Asset Management, LLC | 250,000 | $11.9M | 1.19% | +250,000 | New |
| Renaissance Technologies LLC | 249,514 | $11.9M | 0.02% | +69,800+38.8% | Added |
| Standard Life Aberdeen plc | 246,917 | $11.8M | 0.02% | +27,496+12.5% | Added |
| Privium Fund Management B.V. | 247,267 | $11.2M | 2.85% | +20,274+8.9% | Added |
| Tocqueville Asset Management L.P. | 225,070 | $10.7M | 0.18% | +65,690+41.2% | Added |
| Bank of Montreal | 220,518 | $10.5M | 0.01% | −2,300−1.0% | Reduced |
| Orion Investment Co | 218,570 | $10.4M | 4.15% | +218,570 | New |
| Stifel Financial Corp | 216,140 | $10.3M | 0.01% | −26,319−10.9% | Reduced |
| New York State Common Retirement Fund | 215,716 | $10.3M | 0.01% | +83,006+62.5% | Added |
| ExodusPoint Capital Management, LP | 209,194 | $9.97M | 0.11% | −6,699−3.1% | Reduced |
| Zimmer Partners, LP | 200,000 | $9.53M | 0.18% | −70,300−26.0% | Reduced |
| Nikko Asset Management Americas, Inc. | 199,231 | $9.50M | 0.11% | −21,030−9.5% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 199,231 | $9.50M | 0.01% | −21,030−9.5% | Reduced |
| California Public Employees Retirement System | 196,484 | $9.36M | 0.01% | −7,461−3.7% | Reduced |
| Sicart Associates LLC | 191,523 | $9.13M | 3.50% | −2,470−1.3% | Reduced |
| D. E. Shaw & Co., Inc. | 190,781 | $9.09M | 0.01% | +30,299+18.9% | Added |
| Altrinsic Global Advisors LLC | 187,831 | $8.95M | 0.40% | −7,033−3.6% | Reduced |
| BNP Paribas Arbitrage, SA | 185,944 | $8.86M | 0.01% | −8,415−4.3% | Reduced |
| Jane Street Group, LLC | 179,246 | $8.54M | 0.01% | +61,114+51.7% | Added |
| Rhumbline Advisers | 178,089 | $8.49M | 0.01% | −1,330−0.7% | Reduced |
| Marshall Wace, LLP | 173,199 | $8.25M | 0.01% | +157,756+1,021.5% | Added |
| Sector Gamma AS | 170,000 | $8.10M | 3.03% | −5,507−3.1% | Reduced |
| Rafferty Asset Management, LLC | 168,856 | $8.05M | 0.03% | −39,613−19.0% | Reduced |
| Parkman Healthcare Partners LLC | 161,705 | $7.71M | 1.05% | +20,206+14.3% | Added |
| Cutter Capital Management, LP | 160,166 | $7.63M | 2.33% | −129,200−44.6% | Reduced |
| Caption Management, LLC | 160,000 | $7.63M | 0.81% | +160,000 | New |
| HRT Financial LP | 159,685 | $7.61M | 0.04% | +93,182+140.1% | Added |
| BLB&B Advisors, LLC | 153,750 | $7.33M | 0.40% | +7,650+5.2% | Added |
| UBS Group AG | 152,672 | $7.28M | 0.00% | −19,091−11.1% | Reduced |
| State Board of Administration of Florida Retirement System | 151,055 | $7.20M | 0.01% | −4,090−2.6% | Reduced |
| Tang Capital Management LLC | 150,000 | $7.15M | 0.73% | 00.0% | Unchanged |
| Legal & General Group Plc | 147,644 | $7.04M | 0.00% | −1,844−1.2% | Reduced |
| Sphera Funds Management Ltd. | 140,238 | $6.68M | 1.09% | +140,238 | New |
| Point72 Asset Management, L.P. | 137,210 | $6.54M | 0.02% | −149,392−52.1% | Reduced |
| Sonora Investment Management Group, LLC | 150,814 | $6.54M | 0.51% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 132,736 | $6.33M | 0.01% | −20,679−13.5% | Reduced |
| SEI Investments Co | 132,311 | $6.31M | 0.01% | +52,424+65.6% | Added |
| Peregrine Capital Management LLC | 132,024 | $6.29M | 0.18% | +13,426+11.3% | Added |
| Rhenman & Partners Asset Management AB | 130,000 | $6.20M | 0.59% | +130,000 | New |
| Swedbank AB | 129,373 | $6.17M | 0.01% | −13,268−9.3% | Reduced |
| California State Teachers Retirement System | 129,216 | $6.16M | 0.01% | −2,602−2.0% | Reduced |