Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 357
- −1 vs. Q1 2024
- Shares held
- 143.3M
- +1.29M (+0.9%) vs. Q1 2024
- Total value
- $6.83B
- +$666.0M (+10.8%) vs. Q1 2024
- New holders
- 52
- 120 more added
- Sold out
- 53
- 132 more reduced
3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Millennium Management LLC | 128,215 | $6.11M | 0.01% | −454,964−78.0% | Reduced |
| Amundi | 129,475 | $5.90M | 0.00% | −11,301−8.0% | Reduced |
| Verition Fund Management LLC | 120,814 | $5.76M | 0.04% | −165,133−57.7% | Reduced |
| Granite Investment Partners, LLC | 114,090 | $5.44M | 0.23% | −2,054−1.8% | Reduced |
| Nicola Wealth Management Ltd. | 74,000 | $4.83M | 0.43% | +18,000+32.1% | Added |
| Walleye Capital LLC | 97,871 | $4.66M | 0.05% | +8,741+9.8% | Added |
| Susquehanna International Group, LLP | 95,858 | $4.57M | 0.01% | −43,203−31.1% | Reduced |
| Voya Investment Management LLC | 95,119 | $4.53M | 0.00% | +40,923+75.5% | Added |
| Avidity Partners Management LP | 93,000 | $4.43M | 0.19% | −37,000−28.5% | Reduced |
| DekaBank Deutsche Girozentrale | 93,807 | $4.42M | 0.01% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 88,746 | $4.23M | 0.00% | −20,557−18.8% | Reduced |
| State of Wisconsin Investment Board | 87,700 | $4.18M | 0.01% | −4,115−4.5% | Reduced |
| Davenport & Co LLC | 80,678 | $3.85M | 0.02% | −3,250−3.9% | Reduced |
| Two Sigma Securities, LLC | 80,198 | $3.82M | 0.18% | +69,076+621.1% | Added |
| Envestnet Asset Management Inc | 77,415 | $3.69M | 0.00% | −52,557−40.4% | Reduced |
| Citigroup Inc | 76,618 | $3.65M | 0.00% | −146,325−65.6% | Reduced |
| Commerce Bank | 76,342 | $3.64M | 0.02% | −6,091−7.4% | Reduced |
| Algert Global LLC | 75,350 | $3.59M | 0.12% | +45,108+149.2% | Added |
| Ensign Peak Advisors, Inc | 68,270 | $3.25M | 0.01% | +14,950+28.0% | Added |
| Simplex Trading, LLC | 63,347 | $3.02M | 0.10% | +54,817+642.6% | Added |
| Treasurer of the State of North Carolina | 63,113 | $3.01M | 0.01% | −469−0.7% | Reduced |
| Artia Global Partners LP | 62,479 | $2.98M | 0.76% | +62,479 | New |
| Jefferies Financial Group Inc. | 62,200 | $2.96M | 0.06% | −130,880−67.8% | Reduced |
| GTS Securities LLC | 60,930 | $2.90M | 0.06% | +60,930 | New |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.85M | 0.01% | 00.0% | Unchanged |
| Liontrust Investment Partners LLP | 59,644 | $2.84M | 0.04% | −228,900−79.3% | Reduced |
| Janus Henderson Group PLC | 58,977 | $2.81M | 0.00% | −740−1.2% | Reduced |
| Schroder Investment Management Group | 56,222 | $2.68M | 0.00% | −59,436−51.4% | Reduced |
| State of New Jersey Common Pension Fund D | 55,349 | $2.64M | 0.01% | −26,498−32.4% | Reduced |
| Public Employees Retirement System of Ohio | 55,296 | $2.64M | 0.01% | +803+1.5% | Added |
| Teacher Retirement System of Texas | 52,552 | $2.50M | 0.01% | +23,816+82.9% | Added |
| Bank of Nova Scotia | 51,879 | $2.47M | 0.00% | +51,879 | New |
| LPL Financial LLC | 51,414 | $2.45M | 0.00% | −28,308−35.5% | Reduced |
| Alliancebernstein L.P. | 51,268 | $2.44M | 0.00% | −139,887−73.2% | Reduced |
| DRW Securities, LLC | 50,956 | $2.43M | 0.15% | +50,956 | New |
| Erste Asset Management GmbH | 51,300 | $2.42M | 0.03% | 00.0% | Unchanged |
| Van Eck Associates Corp | 50,264 | $2.40M | 0.00% | −40,837−44.8% | Reduced |
| Tower Research Capital LLC (TRC) | 49,986 | $2.38M | 0.04% | +45,123+927.9% | Added |
| Private Advisor Group, LLC | 46,426 | $2.21M | 0.01% | −1,550−3.2% | Reduced |
| Great West Life Assurance Co | 45,548 | $2.17M | 0.00% | +3,668+8.8% | Added |
| Susquehanna Fundamental Investments, LLC | 45,574 | $2.17M | 0.05% | 00.0% | Unchanged |
| NEOS Investment Management LLC | 45,058 | $2.15M | 0.09% | +7,755+20.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 44,256 | $2.11M | 0.01% | +44,256 | New |
| Susquehanna Portfolio Strategies, LLC | 43,028 | $2.05M | 0.08% | −87,958−67.2% | Reduced |
| UBS Oconnor LLC | 42,595 | $2.03M | 0.06% | +183+0.4% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $2.00M | 0.25% | 00.0% | Unchanged |
| HealthInvest Partners AB | 40,691 | $1.94M | 1.18% | −23,100−36.2% | Reduced |
| Capital Counsel LLC | 37,080 | $1.77M | 0.08% | −2,500−6.3% | Reduced |
| Arizona State Retirement System | 36,722 | $1.75M | 0.01% | +1,235+3.5% | Added |
| Guggenheim Capital LLC | 35,389 | $1.69M | 0.01% | −461−1.3% | Reduced |
| Cubist Systematic Strategies, LLC | 35,311 | $1.68M | 0.03% | −242,480−87.3% | Reduced |
| Grandfield & Dodd, LLC | 34,053 | $1.62M | 0.10% | +279+0.8% | Added |
| Handelsbanken Fonder AB | 33,911 | $1.62M | 0.01% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 31,155 | $1.48M | 0.00% | +3,011+10.7% | Added |
| Trexquant Investment LP | 30,086 | $1.43M | 0.02% | −55,266−64.8% | Reduced |
| Profund Advisors LLC | 29,983 | $1.43M | 0.05% | −1,587−5.0% | Reduced |
| Creative Planning | 26,860 | $1.28M | 0.00% | −145−0.5% | Reduced |
| Blair William & Co | 25,262 | $1.20M | 0.00% | −2,576−9.3% | Reduced |
| Teza Capital Management LLC | 25,159 | $1.20M | 0.15% | −4,777−16.0% | Reduced |
| Assenagon Asset Management S.A. | 24,226 | $1.15M | 0.00% | −247,037−91.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 24,083 | $1.15M | 0.01% | 00.0% | Unchanged |
| Raymond James & Associates | 23,573 | $1.12M | 0.00% | −88,981−79.1% | Reduced |
| Natixis Advisors, L.P. | 23,404 | $1.11M | 0.00% | +376+1.6% | Added |
| DCF Advisers, LLC | 23,000 | $1.10M | 0.57% | +23,000 | New |
| Pathstone Holdings, LLC | 22,705 | $1.08M | 0.00% | +1,452+6.8% | Added |
| Commonwealth Equity Services, LLC | 22,669 | $1.08M | 0.00% | +695+3.2% | Added |
| Mariner, LLC | 21,854 | $1.04M | 0.00% | +1,070+5.1% | Added |
| Brevan Howard Capital Management LP | 21,847 | $1.04M | 0.07% | +16,923+343.7% | Added |
| Comerica Bank | 21,424 | $1.02M | 0.00% | −18,067−45.7% | Reduced |
| Wolverine Trading, LLC | 21,328 | $1.02M | 0.02% | +9,281+77.0% | Added |
| Nicollet Investment Management, Inc. | 20,108 | $958.0K | 0.36% | −413−2.0% | Reduced |
| Toroso Investments, LLC | 18,950 | $903.2K | 0.01% | −1,455−7.1% | Reduced |
| Xponance, Inc. | 18,115 | $863.4K | 0.01% | +1,906+11.8% | Added |
| Janney Montgomery Scott LLC | 17,534 | $836.0K | 0.00% | −9,359−34.8% | Reduced |
| J. Goldman & Co LP | 17,502 | $834.1K | 0.03% | −213,922−92.4% | Reduced |
| Principal Financial Group Inc | 17,458 | $832.0K | 0.00% | −12,366−41.5% | Reduced |
| Victory Capital Management Inc | 17,330 | $825.9K | 0.00% | −307−1.7% | Reduced |
| Inceptionr LLC | 17,289 | $824.0K | 0.23% | +17,289 | New |
| China Universal Asset Management Co., Ltd. | 17,150 | $817.4K | 0.12% | −10,877−38.8% | Reduced |
| NBT Bank N A | 17,050 | $812.6K | 0.06% | 00.0% | Unchanged |
| Simplicity Wealth,LLC | 16,340 | $778.8K | 0.02% | +111+0.7% | Added |
| Bleakley Financial Group, LLC | 16,340 | $778.8K | 0.02% | +111+0.7% | Added |
| Engineers Gate Manager LP | 16,320 | $777.8K | 0.02% | −22,272−57.7% | Reduced |
| Eisler Capital (US) LLC | 16,270 | $775.4K | 0.15% | +16,270 | New |
| First Trust Advisors LP | 16,194 | $771.8K | 0.00% | −159,664−90.8% | Reduced |
| Prudential Financial Inc | 15,717 | $749.1K | 0.00% | +15,717 | New |
| Public Employees Retirement Association of Colorado | 15,589 | $743.0K | 0.00% | −985−5.9% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 15,335 | $730.9K | 0.00% | +1,827+13.5% | Added |
| PEAK6 Investments LLC | 15,001 | $714.9K | 0.03% | +4,001+36.4% | Added |
| Advisor Group Holdings, Inc. | 14,692 | $700.0K | 0.00% | +66+0.5% | Added |
| Tanaka Capital Management Inc | 14,512 | $692.0K | 1.64% | −100−0.7% | Reduced |
| Sanctuary Advisors, LLC | 16,441 | $683.8K | 0.00% | +16,441 | New |
| Neuberger Berman Group LLC | 14,312 | $682.1K | 0.00% | +78+0.5% | Added |
| Chartwell Investment Partners, LLC | 13,759 | $656.0K | 0.02% | +2,003+17.0% | Added |
| North Star Asset Management Inc | 13,640 | $650.1K | 0.03% | 00.0% | Unchanged |
| American Century Companies Inc | 13,441 | $640.6K | 0.00% | +63+0.5% | Added |
| PDT Partners, LLC | 13,430 | $640.1K | 0.06% | +13,430 | New |
| Westmount Partners, LLC | 13,462 | $634.2K | 0.21% | −410−3.0% | Reduced |
| Tudor Investment Corp Et Al | 13,098 | $624.3K | 0.01% | +13,098 | New |
| Martingale Asset Management L P | 12,805 | $610.3K | 0.01% | −510−3.8% | Reduced |