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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
357
−1 vs. Q1 2024
Shares held
143.3M
+1.29M (+0.9%) vs. Q1 2024
Total value
$6.83B
+$666.0M (+10.8%) vs. Q1 2024
New holders
52
120 more added
Sold out
53
132 more reduced

3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 357 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2024: $6.83B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.

Institutions holding IONS in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Stratos Wealth Partners, LTD.12,791$609.6K0.01%+12,791New
Horizon Kinetics Asset Management LLC12,476$594.6K0.01%00.0%Unchanged
Parallax Volatility Advisers, L.P.12,310$586.7K0.01%+12,310New
SpiderRock Advisors, LLC12,026$573.2K0.02%+12,026New
Plancorp, LLC11,286$537.9K0.02%+131+1.2%Added
Northwestern Mutual Wealth Management Co11,213$534.4K0.00%+67+0.6%Added
US Bancorp11,050$526.6K0.00%−877−7.4%Reduced
Brown Advisory Inc10,966$522.6K0.00%−156−1.4%Reduced
Maryland State Retirement & Pension System10,950$521.9K0.01%00.0%Unchanged
Lisanti Capital Growth, LLC10,845$516.9K0.12%−16,990−61.0%Reduced
Suvretta Capital Management, LLC10,800$514.7K0.02%00.0%Unchanged
Twin Tree Management, LP10,381$494.8K0.01%+2,818+37.3%Added
E Fund Management Co., Ltd.10,255$488.8K0.03%+430+4.4%Added
Midwest Professional Planners, LTD.10,140$483.3K0.16%+424+4.4%Added
Cambridge Investment Research Advisors, Inc.10,048$479.0K0.00%+736+7.9%Added
Franklin Resources Inc10,022$477.6K0.00%+213+2.2%Added
Cypress Capital, LLC10,000$476.6K0.13%00.0%Unchanged
International Assets Investment Management, LLC9,707$462.6K0.04%+2,100+27.6%Added
Sectoral Asset Management Inc9,660$460.4K0.19%−440−4.4%Reduced
Amalgamated Bank9,657$460.0K0.00%+454+4.9%Added
Lazard Asset Management LLC9,515$452.0K0.00%+1,660+21.1%Added
Fifth Third Bancorp9,462$451.0K0.00%−171−1.8%Reduced
Annis Gardner Whiting Capital Advisors, LLC9,396$447.8K0.13%+9,396New
The PNC Financial Services Group, Inc.9,361$446.1K0.00%+542+6.1%Added
Deutsche Bank AG9,096$433.5K0.00%+508+5.9%Added
ProShare Advisors LLC9,011$429.5K0.00%−1,205−11.8%Reduced
MetLife Investment Management8,849$421.7K0.00%+1,008+12.9%Added
M&T Bank Corp8,826$420.8K0.00%+2,978+50.9%Added
Ameriprise Financial Inc8,792$419.0K0.00%−6,881−43.9%Reduced
Clearstead Advisors, LLC8,285$394.9K0.01%+7,790+1,573.7%Added
Gsa Capital Partners LLP8,231$392.0K0.03%−94−1.1%Reduced
Virtus ETF Advisers LLC8,009$381.7K0.19%+361+4.7%Added
Truist Financial Corp8,003$381.4K0.00%−1,496−15.7%Reduced
Vontobel Holding Ltd.7,985$380.6K0.00%+488+6.5%Added
Utah Retirement Systems7,900$376.5K0.00%00.0%Unchanged
JustInvest LLC7,624$363.3K0.01%+261+3.5%Added
Castle Rock Wealth Management, LLC6,972$328.5K0.08%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.6,357$300.2K0.00%+6,357New
Gotham Asset Management, LLC6,262$298.4K0.00%−524−7.7%Reduced
Pearl River Capital, LLC6,187$294.9K0.05%−19,772−76.2%Reduced
Jump Financial, LLC6,184$294.7K0.01%−9,509−60.6%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.6,074$289.5K0.00%+2,232+58.1%Added
Oppenheimer Asset Management Inc.5,777$275.3K0.00%−4,049−41.2%Reduced
HighTower Advisors, LLC5,634$271.0K0.00%+549+10.8%Added
Readystate Asset Management LP5,600$266.9K0.01%+5,600New
Perkins Capital Management Inc5,550$265.0K0.25%00.0%Unchanged
Bridgefront Capital, LLC5,559$264.9K0.11%+5,559New
Fox Run Management, L.L.C.5,421$258.4K0.05%+5,421New
HSBC Holdings PLC5,326$252.2K0.00%+5,326New
Buckingham Strategic Wealth, LLC5,251$250.3K0.00%00.0%Unchanged
Stephens Inc5,138$244.9K0.00%−2,715−34.6%Reduced
Advisors Asset Management, Inc.5,074$241.8K0.00%+1,896+59.7%Added
Beaird Harris Wealth Management, LLC5,000$238.3K0.02%00.0%Unchanged
Kestra Advisory Services, LLC5,491$236.2K0.00%−59−1.1%Reduced
Farallon Capital Management, L.L.C.4,800$228.8K0.00%−729,200−99.3%Reduced
Point72 (DIFC) Ltd4,694$223.7K0.02%−23,797−83.5%Reduced
Mitchell & Pahl Private Wealth, LLC4,540$216.4K0.11%+4,540New
Wealth Enhancement Advisory Services, LLC4,508$214.9K0.00%+4,508New
Prospera Financial Services Inc4,451$212.1K0.01%−166−3.6%Reduced
Mirae Asset Global Investments Co., Ltd.4,358$205.8K0.00%−10,723−71.1%Reduced
Checchi Capital Advisers, LLC4,234$201.8K0.02%+4,234New
Ci Investments Inc.3,652$174.0K0.00%−315−7.9%Reduced
Jones Financial Companies LLLP3,401$162.1K0.00%+3,401New
KBC Group NV3,389$162.0K0.00%+244+7.8%Added
Corebridge Financial, Inc.2,761$131.6K0.00%+2,761New
Redwood Wealth Management Group, LLC2,408$114.8K0.09%+2,408New
CWM, LLC2,217$106.0K0.00%−11−0.5%Reduced
GWM Advisors LLC2,150$102.5K0.00%+125+6.2%Added
CIBC Private Wealth Group, LLC2,125$100.4K0.00%−43−2.0%Reduced
ADAR1 Capital Management, LLC1,500$71.5K0.01%−1,400−48.3%Reduced
Twin Lakes Capital Management, LLC1,500$71.5K0.05%00.0%Unchanged
Horizon Investments, LLC1,494$71.2K0.00%−853−36.3%Reduced
Quest Partners LLC1,373$65.4K0.01%−924−40.2%Reduced
IFP Advisors, Inc1,070$51.0K0.00%00.0%Unchanged
Sunbelt Securities, Inc.1,014$48.3K0.00%00.0%Unchanged
Pacer Advisors, Inc.960$45.8K0.00%−11−1.1%Reduced
Harbour Investments, Inc.900$42.9K0.00%00.0%Unchanged
Quadrant Capital Group LLC860$41.0K0.00%+286+49.8%Added
Mather Group, LLC.911$39.5K0.00%+240+35.8%Added
Allworth Financial LP809$38.7K0.00%+13+1.6%Added
Itau Unibanco Holding S.A.767$36.6K0.00%+767New
Manchester Capital Management LLC695$33.1K0.00%+690+13,800.0%Added
Parallel Advisors, LLC632$30.1K0.00%+60+10.5%Added
Steward Partners Investment Advisory, LLC629$30.0K0.00%−94−13.0%Reduced
Archer Investment Corp600$28.6K0.01%−250−29.4%Reduced
Laurel Wealth Advisors LLC600$28.6K0.01%00.0%Unchanged
nVerses Capital, LLC600$28.6K0.02%+600New
AlphaMark Advisors, LLC570$27.0K0.01%+170+42.5%Added
Farther Finance Advisors, LLC563$26.5K0.00%−6−1.1%Reduced
Daiwa Securities Group Inc.541$26.0K0.00%00.0%Unchanged
Pingora Partners LLC500$23.8K0.02%00.0%Unchanged
Riverview Trust Co476$22.7K0.02%00.0%Unchanged
Global Trust Asset Management, LLC474$22.6K0.01%00.0%Unchanged
Danske Bank A/S400$19.1K0.00%+400New
Banque Cantonale Vaudoise400$19.0K0.00%00.0%Unchanged
ORG Partners LLC400$18.8K0.00%+400New
Lindbrook Capital, LLC389$18.5K0.00%+75+23.9%Added
Institutional & Family Asset Management, LLC361$17.2K0.00%−330−47.8%Reduced
GAMMA Investing LLC361$17.2K0.00%−251−41.0%Reduced
Signaturefd, LLC340$16.2K0.00%−15−4.2%Reduced