Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,862,735 | $947.7M | 0.06% | +341,863+1.6% | Added |
| Vanguard Group Inc | 13,430,456 | $582.2M | 0.01% | −773,025−5.4% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,317,112 | $577.3M | 0.35% | +115,659+0.9% | Added |
| BlackRock Inc. | 9,771,891 | $423.6M | 0.01% | +714,361+7.9% | Added |
| Bellevue Group AG | 8,299,514 | $359.8M | 5.49% | −414,473−4.8% | Reduced |
| Wellington Management Group LLP | 5,695,699 | $246.9M | 0.04% | +1,078,721+23.4% | Added |
| Clearbridge Investments, LLC | 4,466,191 | $193.6M | 0.15% | −241,289−5.1% | Reduced |
| State Street Corp | 4,155,664 | $180.1M | 0.01% | +146,867+3.7% | Added |
| Pictet Asset Management Holding SA | 3,739,757 | $163.2M | 0.18% | +221,440+6.3% | Added |
| Price T Rowe Associates Inc | 3,522,203 | $152.7M | 0.02% | −732,871−17.2% | Reduced |
| Tweedy, Browne Co LLC | 3,454,676 | $149.8M | 7.03% | 00.0% | Unchanged |
| Macquarie Group Ltd | 3,200,578 | $138.7M | 0.16% | +112,343+3.6% | Added |
| BVF Inc | 2,428,613 | $105.3M | 2.89% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 2,364,256 | $102.5M | 0.01% | +88,325+3.9% | Added |
| OrbiMed Advisors LLC | 2,013,033 | $87.3M | 1.71% | −51,764−2.5% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,399,852 | $60.7M | 0.42% | −505,204−26.5% | Reduced |
| Deep Track Capital, LP | 1,373,475 | $59.5M | 1.71% | +124,407+10.0% | Added |
| Charles Schwab Investment Management Inc | 1,301,368 | $56.4M | 0.01% | +26,049+2.0% | Added |
| Norges Bank | 1,236,998 | $53.6M | 0.01% | +65,062+5.6% | Added |
| Morgan Stanley | 1,163,598 | $50.4M | 0.00% | +73,335+6.7% | Added |
| Two Sigma Investments, LP | 1,083,879 | $47.0M | 0.12% | +282,431+35.2% | Added |
| Two Sigma Advisers, LP | 1,040,111 | $45.1M | 0.10% | +263,100+33.9% | Added |
| Adage Capital Partners GP, L.L.C. | 1,000,000 | $43.4M | 0.08% | −385,300−27.8% | Reduced |
| Candriam Luxembourg S.C.A. | 911,897 | $39.5M | 0.25% | +282,830+45.0% | Added |
| TD Asset Management Inc | 898,362 | $38.9M | 0.04% | −58,490−6.1% | Reduced |
| Capital World Investors | 839,463 | $36.4M | 0.01% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 778,593 | $33.8M | 0.09% | +438,926+129.2% | Added |
| Squarepoint Ops LLC | 745,173 | $32.3M | 0.13% | +685,969+1,158.7% | Added |
| Farallon Capital Management, L.L.C. | 734,000 | $31.8M | 0.19% | −821,020−52.8% | Reduced |
| Royal Bank of Canada | 732,237 | $31.7M | 0.01% | −42,009−5.4% | Reduced |
| Northern Trust Corp | 692,247 | $30.0M | 0.01% | +4,261+0.6% | Added |
| JPMorgan Chase & Co | 630,979 | $27.4M | 0.00% | −310,053−32.9% | Reduced |
| Bank of America Corp | 606,298 | $26.3M | 0.00% | +151,220+33.2% | Added |
| Wells Fargo & Company | 584,158 | $25.3M | 0.01% | −10,092−1.7% | Reduced |
| Bank of New York Mellon Corp | 583,589 | $25.3M | 0.00% | −57,474−9.0% | Reduced |
| Millennium Management LLC | 583,179 | $25.3M | 0.02% | −307,146−34.5% | Reduced |
| Barclays PLC | 577,387 | $25.0M | 0.01% | −67,121−10.4% | Reduced |
| Jacobs Levy Equity Management, Inc | 571,763 | $24.8M | 0.11% | +62,230+12.2% | Added |
| Nomura Holdings Inc | 470,837 | $20.4M | 0.17% | −18,352−3.8% | Reduced |
| AXA S.A. | 464,815 | $20.1M | 0.06% | +740.0% | Added |
| Pinnacle Associates Ltd | 459,758 | $19.9M | 0.31% | +779+0.2% | Added |
| Invesco Ltd. | 442,887 | $19.2M | 0.00% | +236,986+115.1% | Added |
| Nuveen Asset Management, LLC | 423,030 | $18.3M | 0.01% | +99,024+30.6% | Added |
| First Turn Management, LLC | 421,487 | $18.3M | 2.73% | +64,808+18.2% | Added |
| Artisan Partners Limited Partnership | 416,729 | $18.1M | 0.03% | +416,729 | New |
| Groupama Asset Managment | 257,868 | $17.0M | 0.31% | −99,168−27.8% | Reduced |
| Eversept Partners, LP | 376,438 | $16.3M | 1.22% | +51,784+16.0% | Added |
| Hudson Bay Capital Management LP | 335,500 | $14.5M | 0.13% | +190,500+131.4% | Added |
| C WorldWide Group Holding A/S | 300,000 | $13.0M | 0.15% | 00.0% | Unchanged |
| Baillie Gifford & Co | 295,683 | $12.8M | 0.01% | −2,800−0.9% | Reduced |
| Cutter Capital Management, LP | 289,366 | $12.5M | 4.84% | +289,366 | New |
| Liontrust Investment Partners LLP | 288,544 | $12.5M | 0.17% | +4,563+1.6% | Added |
| Point72 Asset Management, L.P. | 286,602 | $12.4M | 0.04% | −682,198−70.4% | Reduced |
| Verition Fund Management LLC | 285,947 | $12.4M | 0.12% | +143,093+100.2% | Added |
| Cubist Systematic Strategies, LLC | 277,791 | $12.0M | 0.14% | +78,314+39.3% | Added |
| Assenagon Asset Management S.A. | 271,263 | $11.8M | 0.03% | +86,862+47.1% | Added |
| Zimmer Partners, LP | 270,300 | $11.7M | 0.25% | +270,300 | New |
| CI Private Wealth, LLC | 267,291 | $11.6M | 0.02% | −210.0% | Reduced |
| Swiss National Bank | 254,900 | $11.0M | 0.01% | +600+0.2% | Added |
| Man Group plc | 253,221 | $11.0M | 0.03% | +174,746+222.7% | Added |
| Kennedy Capital Management, Inc. | 249,527 | $10.8M | 0.22% | +21,102+9.2% | Added |
| Manufacturers Life Insurance Company, The | 245,067 | $10.6M | 0.01% | −15,635−6.0% | Reduced |
| Bank of Montreal | 222,818 | $10.5M | 0.01% | −571−0.3% | Reduced |
| Stifel Financial Corp | 242,459 | $10.5M | 0.01% | −3,570−1.5% | Reduced |
| J. Goldman & Co LP | 231,424 | $10.0M | 0.45% | +231,424 | New |
| Privium Fund Management B.V. | 226,993 | $9.84M | 2.63% | +9,500+4.4% | Added |
| Citigroup Inc | 222,943 | $9.66M | 0.01% | +122,698+122.4% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 220,261 | $9.55M | 0.01% | −32,198−12.8% | Reduced |
| Nikko Asset Management Americas, Inc. | 220,261 | $9.55M | 0.09% | −32,198−12.8% | Reduced |
| Standard Life Aberdeen plc | 219,421 | $9.51M | 0.02% | +83,002+60.8% | Added |
| ExodusPoint Capital Management, LP | 215,893 | $9.36M | 0.12% | +192,409+819.3% | Added |
| Rafferty Asset Management, LLC | 208,469 | $9.04M | 0.03% | +24,073+13.1% | Added |
| California Public Employees Retirement System | 203,945 | $8.84M | 0.01% | −5,491−2.6% | Reduced |
| Goldman Sachs Group Inc | 200,380 | $8.69M | 0.00% | −181,002−47.5% | Reduced |
| Altrinsic Global Advisors LLC | 194,864 | $8.45M | 0.38% | −14,288−6.8% | Reduced |
| BNP Paribas Arbitrage, SA | 194,359 | $8.43M | 0.01% | −160,596−45.2% | Reduced |
| Sicart Associates LLC | 193,993 | $8.41M | 3.08% | −300−0.2% | Reduced |
| Jefferies Financial Group Inc. | 193,080 | $8.37M | 0.17% | −9,220−4.6% | Reduced |
| Voloridge Investment Management, LLC | 191,367 | $8.30M | 0.03% | −72,754−27.5% | Reduced |
| Alliancebernstein L.P. | 191,155 | $8.29M | 0.00% | −66,165−25.7% | Reduced |
| UBS Asset Management Americas Inc | 186,327 | $8.08M | 0.00% | 00.0% | Unchanged |
| Credit Suisse AG | 182,509 | $7.91M | 0.01% | −7,213−3.8% | Reduced |
| Renaissance Technologies LLC | 179,714 | $7.79M | 0.01% | +67,300+59.9% | Added |
| Rhumbline Advisers | 179,419 | $7.78M | 0.01% | −19,997−10.0% | Reduced |
| First Trust Advisors LP | 175,858 | $7.62M | 0.01% | −921,872−84.0% | Reduced |
| Sector Gamma AS | 175,507 | $7.61M | 2.14% | +30,495+21.0% | Added |
| UBS Group AG | 171,763 | $7.45M | 0.00% | +12,024+7.5% | Added |
| Schonfeld Strategic Advisors LLC | 170,860 | $7.41M | 0.06% | −142,414−45.5% | Reduced |
| D. E. Shaw & Co., Inc. | 160,482 | $6.96M | 0.01% | +41,324+34.7% | Added |
| Tocqueville Asset Management L.P. | 159,380 | $6.91M | 0.11% | −400−0.3% | Reduced |
| Russell Investments Group, Ltd. | 153,415 | $6.65M | 0.01% | −4,387−2.8% | Reduced |
| Sonora Investment Management Group, LLC | 150,814 | $6.54M | 0.51% | +1,476+1.0% | Added |
| Tang Capital Management LLC | 150,000 | $6.50M | 0.68% | −50,000−25.0% | Reduced |
| Legal & General Group Plc | 149,488 | $6.48M | 0.00% | −5,860−3.8% | Reduced |
| BLB&B Advisors, LLC | 146,100 | $6.33M | 0.36% | −1,000−0.7% | Reduced |
| Swedbank AB | 142,641 | $6.18M | 0.01% | +1,643+1.2% | Added |
| Parkman Healthcare Partners LLC | 141,499 | $6.13M | 0.75% | −69,901−33.1% | Reduced |
| Susquehanna International Group, LLP | 139,061 | $6.03M | 0.01% | +84,928+156.9% | Added |
| Senator Investment Group LP | 135,000 | $5.85M | 0.27% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 132,710 | $5.75M | 0.01% | +27,381+26.0% | Added |