Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 338
- −24 vs. Q1 2021
- Shares held
- 124.4M
- +2.62M (+2.2%) vs. Q1 2021
- Total value
- $4.96B
- −$516.2M (−9.4%) vs. Q1 2021
- New holders
- 51
- 116 more added
- Sold out
- 75
- 103 more reduced
3 institutions that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,144,455 | $843.5M | 0.07% | +50,559+0.2% | Added |
| Vanguard Group Inc | 12,655,829 | $504.8M | 0.01% | +51,680+0.4% | Added |
| Price T Rowe Associates Inc | 12,258,827 | $489.0M | 0.05% | −321,229−2.6% | Reduced |
| Bellevue Group AG | 9,930,245 | $396.1M | 3.87% | +946,011+10.5% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 8,907,733 | $355.3M | 0.66% | +3,765,462+73.2% | Added |
| BlackRock Inc. | 8,179,666 | $326.3M | 0.01% | −1,628,896−16.6% | Reduced |
| Clearbridge Investments, LLC | 6,815,601 | $271.9M | 0.19% | −587,366−7.9% | Reduced |
| State Street Corp | 3,230,951 | $128.9M | 0.01% | −178,620−5.2% | Reduced |
| JPMorgan Chase & Co | 2,275,706 | $90.8M | 0.01% | +312,483+15.9% | Added |
| Camber Capital Management LP | 2,000,000 | $79.8M | 3.13% | +1,000,000+100.0% | Added |
| Geode Capital Management, LLC | 1,762,540 | $70.3M | 0.01% | +33,394+1.9% | Added |
| First Trust Advisors LP | 1,522,449 | $60.7M | 0.07% | +354,640+30.4% | Added |
| Rockefeller Capital Management L.P. | 1,324,611 | $52.8M | 0.30% | +590,632+80.5% | Added |
| Swedbank AB | 1,117,275 | $44.6M | 0.08% | −3,792−0.3% | Reduced |
| Jacobs Levy Equity Management, Inc | 1,084,422 | $43.3M | 0.29% | +921,476+565.5% | Added |
| Point72 Asset Management, L.P. | 976,900 | $39.0M | 0.19% | +976,900 | New |
| Woodline Partners LP | 963,788 | $38.4M | 0.72% | +487,897+102.5% | Added |
| Norges Bank | 896,289 | $35.8M | 0.01% | +88,801+11.0% | Added |
| Wells Fargo & Company | 841,431 | $33.6M | 0.01% | −315,568−27.3% | Reduced |
| Millennium Management LLC | 795,842 | $31.7M | 0.04% | +164,578+26.1% | Added |
| Renaissance Technologies LLC | 776,414 | $31.0M | 0.04% | +189,000+32.2% | Added |
| Nuveen Asset Management, LLC | 723,101 | $28.8M | 0.01% | −226,136−23.8% | Reduced |
| Bank of America Corp | 717,497 | $28.6M | 0.00% | +25,914+3.7% | Added |
| Charles Schwab Investment Management Inc | 713,960 | $28.5M | 0.01% | +17,464+2.5% | Added |
| Goldman Sachs Group Inc | 679,429 | $27.1M | 0.01% | −65,481−8.8% | Reduced |
| Northern Trust Corp | 671,573 | $26.8M | 0.00% | −169,572−20.2% | Reduced |
| Candriam Luxembourg S.C.A. | 552,566 | $22.0M | 0.15% | +305,612+123.8% | Added |
| Citadel Advisors LLC | 545,480 | $21.8M | 0.02% | +375,631+221.2% | Added |
| Pinnacle Associates Ltd | 541,342 | $21.6M | 0.39% | +28,218+5.5% | Added |
| Bank of New York Mellon Corp | 540,529 | $21.6M | 0.00% | −4,569−0.8% | Reduced |
| Morgan Stanley | 527,609 | $21.0M | 0.00% | −40,058−7.1% | Reduced |
| Two Sigma Advisers, LP | 525,811 | $21.0M | 0.06% | −188,600−26.4% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 524,326 | $20.9M | 0.01% | −376,975−41.8% | Reduced |
| Nikko Asset Management Americas, Inc. | 508,374 | $20.4M | 0.08% | +10,118+2.0% | Added |
| Royal Bank of Canada | 484,966 | $19.3M | 0.01% | +325,352+203.8% | Added |
| Altrinsic Global Advisors LLC | 456,226 | $18.2M | 0.55% | +15,172+3.4% | Added |
| Eversept Partners, LP | 442,000 | $17.6M | 1.63% | +442,000 | New |
| Dimensional Fund Advisors LP | 410,217 | $16.4M | 0.01% | −47,064−10.3% | Reduced |
| TD Asset Management Inc | 421,864 | $15.7M | 0.02% | −2,715−0.6% | Reduced |
| Susquehanna International Group, LLP | 380,466 | $15.2M | 0.02% | +292,195+331.0% | Added |
| Bank of Montreal | 381,485 | $15.1M | 0.01% | +59,255+18.4% | Added |
| Stifel Financial Corp | 377,685 | $15.1M | 0.02% | −2,713−0.7% | Reduced |
| Nomura Holdings Inc | 377,728 | $15.0M | 0.12% | +377,728 | New |
| Sicart Associates LLC | 368,409 | $14.7M | 3.50% | −1,889−0.5% | Reduced |
| Barclays PLC | 363,996 | $14.5M | 0.01% | +265,225+268.5% | Added |
| Invesco Ltd. | 340,613 | $13.6M | 0.00% | −2,018,821−85.6% | Reduced |
| Tekla Capital Management LLC | 322,521 | $12.9M | 0.42% | +106,150+49.1% | Added |
| California Public Employees Retirement System | 320,680 | $12.8M | 0.01% | +4,103+1.3% | Added |
| Two Sigma Investments, LP | 306,488 | $12.2M | 0.03% | +120,768+65.0% | Added |
| Dowling & Yahnke LLC | 303,150 | $12.1M | 0.69% | −700.0% | Reduced |
| Raymond James & Associates | 293,938 | $11.7M | 0.01% | −8,137−2.7% | Reduced |
| Bank Julius Baer & Co. Ltd, Zurich | 288,844 | $11.5M | 0.07% | +917+0.3% | Added |
| Swiss National Bank | 279,900 | $11.2M | 0.01% | −230,459−45.2% | Reduced |
| Baillie Gifford & Co | 271,396 | $10.8M | 0.01% | +33,437+14.1% | Added |
| Sector Gamma AS | 263,488 | $10.5M | 1.86% | −190,662−42.0% | Reduced |
| Balyasny Asset Management LLC | 263,286 | $10.5M | 0.06% | +263,286 | New |
| Worldquant Millennium Advisors LLC | 251,075 | $10.0M | 0.22% | +251,075 | New |
| California State Teachers Retirement System | 243,722 | $9.72M | 0.01% | −1,361−0.6% | Reduced |
| Citigroup Inc | 242,123 | $9.66M | 0.01% | +7,103+3.0% | Added |
| New York State Common Retirement Fund | 241,159 | $9.62M | 0.01% | +42,928+21.7% | Added |
| Deutsche Bank AG | 234,386 | $9.35M | 0.00% | +73,819+46.0% | Added |
| American Century Companies Inc | 226,180 | $9.02M | 0.01% | −716,498−76.0% | Reduced |
| Russell Investments Group, Ltd. | 221,554 | $8.84M | 0.01% | +190,623+616.3% | Added |
| Parametric Portfolio Associates LLC | 220,212 | $8.78M | 0.00% | −1,589−0.7% | Reduced |
| Morningstar Investment Services LLC | 210,107 | $8.31M | 0.10% | +7,400+3.7% | Added |
| Hudson Bay Capital Management LP | 185,000 | $7.38M | 0.09% | +54,600+41.9% | Added |
| Majedie Asset Management Ltd | 184,462 | $7.36M | 0.48% | +62,763+51.6% | Added |
| International Biotechnology Trust PLC | 181,781 | $7.25M | 1.93% | −152,000−45.5% | Reduced |
| Cubist Systematic Strategies, LLC | 178,142 | $7.11M | 0.08% | +178,142 | New |
| Marshall Wace, LLP | 176,820 | $7.05M | 0.04% | +176,820 | New |
| UBS Asset Management Americas Inc | 176,341 | $7.03M | 0.00% | −228,183−56.4% | Reduced |
| Ergoteles LLC | 176,253 | $7.03M | 0.16% | +176,253 | New |
| Tocqueville Asset Management L.P. | 172,200 | $6.87M | 0.10% | −73,292−29.9% | Reduced |
| Sonora Investment Management, LLC | 168,665 | $6.73M | 0.88% | +4,742+2.9% | Added |
| State Board of Administration of Florida Retirement System | 164,108 | $6.55M | 0.01% | −4,865−2.9% | Reduced |
| Peregrine Capital Management LLC | 162,528 | $6.48M | 0.12% | −9,820−5.7% | Reduced |
| Credit Suisse AG | 159,185 | $6.35M | 0.00% | +26,191+19.7% | Added |
| BLB&B Advisors, LLC | 157,490 | $6.28M | 0.45% | +870+0.6% | Added |
| UBS Group AG | 155,129 | $6.19M | 0.00% | +126,067+433.8% | Added |
| Van Eck Associates Corp | 147,383 | $5.88M | 0.01% | −22,609−13.3% | Reduced |
| PDT Partners, LLC | 141,925 | $5.66M | 0.37% | +141,925 | New |
| Rhumbline Advisers | 139,585 | $5.57M | 0.01% | −4,821−3.3% | Reduced |
| Parkman Healthcare Partners LLC | 136,380 | $5.44M | 1.19% | +30,583+28.9% | Added |
| Pictet Asset Management Ltd | 134,324 | $5.36M | 0.01% | +85,324+174.1% | Added |
| Legal & General Group Plc | 125,883 | $5.02M | 0.00% | −294,494−70.1% | Reduced |
| Thrivent Financial for Lutherans | 123,367 | $4.92M | 0.01% | +2,054+1.7% | Added |
| Davenport & Co LLC | 116,963 | $4.66M | 0.04% | −7,775−6.2% | Reduced |
| Wolverine Trading, LLC | 110,948 | $4.39M | 0.12% | +1,337+1.2% | Added |
| DekaBank Deutsche Girozentrale | 107,576 | $4.26M | 0.01% | −9,819−8.4% | Reduced |
| Tudor Investment Corp Et Al | 99,886 | $3.98M | 0.08% | +99,886 | New |
| Caption Management, LLC | 96,007 | $3.83M | 0.34% | +96,007 | New |
| Envestnet Asset Management Inc | 95,720 | $3.82M | 0.00% | +13,400+16.3% | Added |
| Arrowstreet Capital, Limited Partnership | 92,900 | $3.71M | 0.00% | +92,900 | New |
| Susquehanna Fundamental Investments, LLC | 88,273 | $3.52M | 0.06% | +33,469+61.1% | Added |
| State of New Jersey Common Pension Fund D | 86,745 | $3.46M | 0.01% | +1,822+2.1% | Added |
| Public Employees Retirement System of Ohio | 80,054 | $3.19M | 0.01% | +10,669+15.4% | Added |
| Sabby Management, LLC | 78,000 | $3.11M | 0.67% | +23,312+42.6% | Added |
| Rhenman & Partners Asset Management AB | 75,000 | $2.99M | 0.20% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 74,666 | $2.98M | 0.00% | +66,560+821.1% | Added |
| PFS Investments Inc. | 75,715 | $2.94M | 0.07% | +5,211+7.4% | Added |