Skip to main content

Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
365
No complete 13F data for Q4 2020
Shares held
123.5M
No complete 13F data for Q4 2020
Total value
$5.55B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 365 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2021: $5.55B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc.

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding IONS in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC21,093,896$948.4M0.08%––
Vanguard Group Inc12,604,149$566.7M0.02%––
Price T Rowe Associates Inc12,580,056$565.6M0.06%––
BlackRock Inc.9,808,562$441.0M0.01%––
Bellevue Group AG8,984,234$403.9M4.27%––
Clearbridge Investments, LLC7,402,967$332.8M0.25%––
ARK Investment Management LLCSuperinvestorARK Invest5,142,271$231.2M0.46%––
State Street Corp3,409,571$153.3M0.01%––
Invesco Ltd.2,359,434$106.1M0.03%––
JPMorgan Chase & Co1,963,223$88.3M0.01%––
Geode Capital Management, LLC1,729,146$77.6M0.01%––
Waddell & Reed Financial Inc1,613,947$72.6M0.15%––
BVF Inc1,364,461$61.3M2.30%––
First Trust Advisors LP1,167,809$52.5M0.06%––
Wells Fargo & Company1,156,999$52.0M0.01%––
Swedbank AB1,121,067$50.4M0.10%––
Camber Capital Management LP1,000,000$45.0M1.79%––
Nuveen Asset Management, LLC949,237$42.7M0.01%––
American Century Companies Inc942,678$42.4M0.03%––
Sumitomo Mitsui Trust Holdings, Inc.901,301$40.5M0.03%––
Northern Trust Corp841,145$37.8M0.01%––
Norges Bank807,488$36.3M0.01%––
Goldman Sachs Group Inc744,910$33.5M0.01%––
Rockefeller Capital Management L.P.733,979$33.0M0.22%––
Two Sigma Advisers, LP714,411$32.1M0.09%––
Charles Schwab Investment Management Inc696,496$31.3M0.01%––
Bank of America Corp691,583$31.1M0.00%––
Millennium Management LLC631,264$28.4M0.04%––
Farallon Capital Management, L.L.C.630,500$28.3M0.15%––
Renaissance Technologies LLC587,414$26.4M0.03%––
Morgan Stanley567,667$25.5M0.00%––
Bank of New York Mellon Corp545,098$24.5M0.01%––
Pinnacle Associates Ltd513,124$23.1M0.44%––
Swiss National Bank510,359$22.9M0.02%––
Nikko Asset Management Americas, Inc.498,256$22.4M0.11%––
Woodline Partners LP475,891$21.4M0.47%––
Dimensional Fund Advisors LP457,281$20.6M0.01%––
Sector Gamma AS454,150$20.4M3.74%––
Altrinsic Global Advisors LLC441,054$19.8M0.62%––
Alyeska Investment Group, L.P.427,990$19.2M0.25%––
TD Asset Management Inc424,579$19.1M0.02%––
Legal & General Group Plc420,377$18.9M0.01%––
UBS Asset Management Americas Inc404,524$18.2M0.01%––
Stifel Financial Corp380,398$17.1M0.03%––
First Manhattan Co375,300$16.9M0.07%––
Sicart Associates LLC370,298$16.6M4.40%––
International Biotechnology Trust PLC333,781$15.0M3.97%––
Verition Fund Management LLC319,539$14.4M0.26%––
California Public Employees Retirement System316,577$14.2M0.01%––
Bank of Montreal322,230$13.8M0.01%––
Dowling & Yahnke LLC303,220$13.6M0.93%––
Raymond James & Associates302,075$13.6M0.01%––
Candriam Luxembourg S.C.A.246,954$13.4M0.11%––
Bank Julius Baer & Co. Ltd, Zurich287,927$12.9M0.10%––
Tocqueville Asset Management L.P.245,492$11.0M0.17%––
California State Teachers Retirement System245,083$11.0M0.01%––
Baillie Gifford & Co237,959$10.7M0.01%––
Citigroup Inc235,020$10.6M0.01%––
Parametric Portfolio Associates LLC221,801$9.97M0.01%––
Tekla Capital Management LLC216,371$9.73M0.33%––
Morningstar Investment Services LLC202,707$9.06M0.12%––
New York State Common Retirement Fund198,231$8.91M0.01%––
AXA S.A.192,629$8.66M0.03%––
Two Sigma Investments, LP185,720$8.35M0.03%––
Peregrine Capital Management LLC172,348$7.75M0.14%––
Van Eck Associates Corp169,992$7.64M0.02%––
Citadel Advisors LLC169,849$7.64M0.01%––
State Board of Administration of Florida Retirement System168,973$7.60M0.02%––
Sonora Investment Management, LLC163,923$7.37M0.58%––
Jacobs Levy Equity Management, Inc162,946$7.33M0.06%––
Deutsche Bank AG160,567$7.22M0.00%––
Royal Bank of Canada159,614$7.18M0.00%––
BLB&B Advisors, LLC156,620$7.04M0.55%––
Sphera Funds Management Ltd.145,476$6.54M0.60%––
Rhumbline Advisers144,406$6.49M0.01%––
Credit Suisse AG132,994$5.98M0.00%––
Hudson Bay Capital Management LP130,400$5.86M0.08%––
Davenport & Co LLC124,738$5.61M0.05%––
Majedie Asset Management Ltd121,699$5.47M0.40%––
Thrivent Financial for Lutherans121,313$5.45M0.01%––
DekaBank Deutsche Girozentrale117,395$5.24M0.02%––
Wolverine Trading, LLC109,611$4.90M0.09%––
Parkman Healthcare Partners LLC105,797$4.76M1.15%––
Barclays PLC98,771$4.44M0.00%––
Susquehanna International Group, LLP88,271$3.97M0.01%––
Edmond de Rothschild Holding S.A.86,250$3.88M0.11%––
State of New Jersey Common Pension Fund D84,923$3.82M0.01%––
Envestnet Asset Management Inc82,320$3.70M0.00%––
Amundi Asset Management US, Inc.82,126$3.69M0.00%––
Mitsubishi UFJ Trust & Banking Corp79,951$3.60M0.01%––
Alliancebernstein L.P.77,300$3.48M0.00%––
Janus Henderson Group PLC76,644$3.45M0.00%––
Rhenman & Partners Asset Management AB75,000$3.37M0.24%––
State of Wisconsin Investment Board72,205$3.25M0.01%––
Guggenheim Capital LLC71,392$3.21M0.02%––
PFS Investments Inc.70,504$3.17M0.08%––
Public Employees Retirement System of Ohio69,385$3.12M0.01%––
Rafferty Asset Management, LLC62,884$2.83M0.02%––
Asset Management One Co.,Ltd.60,617$2.73M0.01%––
Andra AP-fonden59,700$2.68M0.06%––