Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 312
- +12 vs. Q2 2023
- Shares held
- 139.7M
- +6.44M (+4.8%) vs. Q2 2023
- Total value
- $6.35B
- +$878.1M (+16.1%) vs. Q2 2023
- New holders
- 39
- 101 more added
- Sold out
- 27
- 103 more reduced
5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,498,922 | $975.2M | 0.08% | +35,106+0.2% | Added |
| Vanguard Group Inc | 14,502,025 | $657.8M | 0.02% | −21,241−0.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,123,055 | $595.3M | 0.42% | +39,328+0.3% | Added |
| Bellevue Group AG | 9,233,700 | $418.8M | 6.75% | −146,600−1.6% | Reduced |
| BlackRock Inc. | 9,114,627 | $413.4M | 0.01% | −21,547−0.2% | Reduced |
| Clearbridge Investments, LLC | 4,840,695 | $219.6M | 0.21% | −346,509−6.7% | Reduced |
| BVF Inc | 4,004,613 | $181.6M | 4.90% | +1,158,598+40.7% | Added |
| State Street Corp | 3,955,029 | $179.4M | 0.01% | −19,424−0.5% | Reduced |
| Price T Rowe Associates Inc | 3,757,997 | $170.5M | 0.03% | −77,870−2.0% | Reduced |
| Tweedy, Browne Co LLC | 3,510,173 | $159.2M | 8.52% | −30,685−0.9% | Reduced |
| Pictet Asset Management Holding SA | 3,240,934 | $147.0M | 0.18% | +3,240,934 | New |
| Macquarie Group Ltd | 2,935,924 | $133.2M | 0.17% | +1,437,042+95.9% | Added |
| Deep Track Capital, LP | 2,834,069 | $128.6M | 4.99% | 00.0% | Unchanged |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,366,367 | $107.3M | 0.82% | −56,264−2.3% | Reduced |
| Camber Capital Management LP | 2,250,000 | $102.1M | 3.66% | −250,000−10.0% | Reduced |
| Geode Capital Management, LLC | 2,194,731 | $99.6M | 0.01% | +37,863+1.8% | Added |
| OrbiMed Advisors LLC | 2,169,500 | $98.4M | 2.28% | 00.0% | Unchanged |
| Wellington Management Group LLP | 1,760,625 | $79.9M | 0.02% | +845,902+92.5% | Added |
| Charles Schwab Investment Management Inc | 1,242,307 | $56.4M | 0.02% | +43,087+3.6% | Added |
| Norges Bank | 1,153,926 | $52.3M | 0.01% | +141,308+14.0% | Added |
| First Trust Advisors LP | 1,134,979 | $51.5M | 0.06% | −188,053−14.2% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,067,000 | $48.4M | 0.11% | +1,067,000 | New |
| Morgan Stanley | 1,033,404 | $46.9M | 0.00% | −95,484−8.5% | Reduced |
| JPMorgan Chase & Co | 901,057 | $40.9M | 0.00% | −166,666−15.6% | Reduced |
| TD Asset Management Inc | 898,852 | $40.8M | 0.05% | +113,644+14.5% | Added |
| Capital World Investors | 839,463 | $38.1M | 0.01% | 00.0% | Unchanged |
| Farallon Capital Management, L.L.C. | 727,000 | $33.0M | 0.19% | +722,000+14,440.0% | Added |
| Northern Trust Corp | 690,724 | $31.3M | 0.01% | +19,646+2.9% | Added |
| Royal Bank of Canada | 663,444 | $30.1M | 0.01% | +86,306+15.0% | Added |
| California Public Employees Retirement System | 655,371 | $29.7M | 0.03% | +397,897+154.5% | Added |
| Barclays PLC | 639,553 | $29.0M | 0.02% | +97,321+17.9% | Added |
| Bank of New York Mellon Corp | 627,159 | $28.4M | 0.01% | +69,405+12.4% | Added |
| Wells Fargo & Company | 617,930 | $28.0M | 0.01% | +5,039+0.8% | Added |
| Two Sigma Advisers, LP | 604,311 | $27.4M | 0.07% | +260,100+75.6% | Added |
| Candriam Luxembourg S.C.A. | 549,067 | $24.9M | 0.20% | +25,000+4.8% | Added |
| Bank of America Corp | 536,044 | $24.3M | 0.00% | +76,725+16.7% | Added |
| Citadel Advisors LLC | 535,918 | $24.3M | 0.03% | −185,860−25.8% | Reduced |
| AXA S.A. | 481,582 | $21.8M | 0.08% | −43,582−8.3% | Reduced |
| Two Sigma Investments, LP | 476,057 | $21.6M | 0.06% | +262,685+123.1% | Added |
| Pinnacle Associates Ltd | 463,035 | $21.0M | 0.39% | −15,169−3.2% | Reduced |
| Nomura Holdings Inc | 459,311 | $20.8M | 0.23% | +23,931+5.5% | Added |
| Millennium Management LLC | 437,123 | $19.8M | 0.02% | +18,210+4.3% | Added |
| BNP Paribas Arbitrage, SA | 410,674 | $18.6M | 0.04% | +300,158+271.6% | Added |
| Jacobs Levy Equity Management, Inc | 373,117 | $16.9M | 0.10% | −176,441−32.1% | Reduced |
| D. E. Shaw & Co., Inc. | 362,045 | $16.4M | 0.03% | +165,832+84.5% | Added |
| Goldman Sachs Group Inc | 337,827 | $15.3M | 0.00% | +149,455+79.3% | Added |
| Baillie Gifford & Co | 316,629 | $14.4M | 0.01% | −13,717−4.2% | Reduced |
| Woodline Partners LP | 315,094 | $14.3M | 0.17% | −726,838−69.8% | Reduced |
| Liontrust Investment Partners LLP | 310,026 | $14.1M | 0.22% | −11,548−3.6% | Reduced |
| Nuveen Asset Management, LLC | 309,144 | $14.0M | 0.00% | −32,307−9.5% | Reduced |
| CI Private Wealth, LLC | 306,990 | $13.9M | 0.03% | +1,522+0.5% | Added |
| Alliancebernstein L.P. | 304,518 | $13.8M | 0.01% | −42,020−12.1% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 292,473 | $13.3M | 0.01% | −3,659−1.2% | Reduced |
| Nikko Asset Management Americas, Inc. | 292,473 | $13.3M | 0.16% | −3,659−1.2% | Reduced |
| Altrinsic Global Advisors LLC | 292,184 | $13.3M | 0.51% | −15,806−5.1% | Reduced |
| Swiss National Bank | 283,100 | $12.8M | 0.01% | +3,000+1.1% | Added |
| Renaissance Technologies LLC | 269,800 | $12.2M | 0.02% | −100,700−27.2% | Reduced |
| Jane Street Group, LLC | 253,491 | $11.5M | 0.02% | +145,167+134.0% | Added |
| Eversept Partners, LP | 252,446 | $11.5M | 1.27% | +10,874+4.5% | Added |
| Stifel Financial Corp | 246,203 | $11.2M | 0.02% | −22,778−8.5% | Reduced |
| Kennedy Capital Management, Inc. | 238,635 | $10.8M | 0.26% | +8,374+3.6% | Added |
| Credit Suisse AG | 230,343 | $10.4M | 0.01% | −14,639−6.0% | Reduced |
| Manufacturers Life Insurance Company, The | 229,677 | $10.4M | 0.01% | −33,882−12.9% | Reduced |
| Privium Fund Management B.V. | 228,493 | $10.4M | 3.08% | +2,000+0.9% | Added |
| Bank of Montreal | 226,821 | $10.1M | 0.01% | +3,690+1.7% | Added |
| Rafferty Asset Management, LLC | 215,971 | $9.80M | 0.06% | +11,583+5.7% | Added |
| Sicart Associates LLC | 203,132 | $9.21M | 3.61% | −1,815−0.9% | Reduced |
| Tang Capital Management LLC | 200,000 | $9.07M | 1.28% | 00.0% | Unchanged |
| Rhumbline Advisers | 197,460 | $8.96M | 0.01% | +127+0.1% | Added |
| Raymond James & Associates | 194,629 | $8.83M | 0.01% | +2,745+1.4% | Added |
| Dimensional Fund Advisors LP | 192,160 | $8.72M | 0.00% | +9,446+5.2% | Added |
| Hudson Bay Capital Management LP | 190,000 | $8.62M | 0.08% | −85,000−30.9% | Reduced |
| Citigroup Inc | 189,620 | $8.60M | 0.01% | +107,873+132.0% | Added |
| Trexquant Investment LP | 183,349 | $8.32M | 0.21% | +78,724+75.2% | Added |
| UBS Asset Management Americas Inc | 177,114 | $8.03M | 0.00% | +381+0.2% | Added |
| Sector Gamma AS | 165,616 | $7.51M | 1.92% | +5,215+3.3% | Added |
| Legal & General Group Plc | 165,035 | $7.49M | 0.00% | +31,692+23.8% | Added |
| Man Group plc | – | $7.44M | 0.02% | – | New |
| Tocqueville Asset Management L.P. | 161,730 | $7.34M | 0.14% | −750−0.5% | Reduced |
| Jefferies Financial Group Inc. | 160,210 | $7.27M | 0.18% | +67,210+72.3% | Added |
| Parkman Healthcare Partners LLC | 159,503 | $7.24M | 1.33% | +6,451+4.2% | Added |
| State Board of Administration of Florida Retirement System | 150,988 | $6.85M | 0.02% | +220+0.1% | Added |
| Sonora Investment Management Group, LLC | 148,450 | $6.73M | 0.58% | −1,755−1.2% | Reduced |
| BLB&B Advisors, LLC | 147,650 | $6.70M | 0.48% | −2,650−1.8% | Reduced |
| California State Teachers Retirement System | 145,582 | $6.60M | 0.01% | −15,416−9.6% | Reduced |
| Point72 Asset Management, L.P. | 141,500 | $6.42M | 0.02% | −62,900−30.8% | Reduced |
| Squarepoint Ops LLC | 139,520 | $6.33M | 0.03% | +71,711+105.8% | Added |
| Swedbank AB | 136,939 | $6.21M | 0.01% | −799,809−85.4% | Reduced |
| Verition Fund Management LLC | 136,031 | $6.17M | 0.08% | +136,031 | New |
| Amundi | 125,664 | $6.03M | 0.00% | +4,818+4.0% | Added |
| Invesco Ltd. | 131,167 | $5.95M | 0.00% | +1,449+1.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 129,812 | $5.89M | 0.03% | −68,696−34.6% | Reduced |
| Envestnet Asset Management Inc | 126,736 | $5.75M | 0.00% | +90,667+251.4% | Added |
| Peregrine Capital Management LLC | 126,393 | $5.73M | 0.17% | −22,805−15.3% | Reduced |
| Jump Financial, LLC | 119,400 | $5.42M | 0.20% | +13,632+12.9% | Added |
| New York State Common Retirement Fund | 118,229 | $5.36M | 0.01% | −17,327−12.8% | Reduced |
| HRT Financial LP | 114,600 | $5.20M | 0.05% | +109,117+1,990.1% | Added |
| UBS Group AG | 109,034 | $4.95M | 0.00% | +16,209+17.5% | Added |
| State of Wisconsin Investment Board | 105,765 | $4.80M | 0.01% | −3,545−3.2% | Reduced |
| DekaBank Deutsche Girozentrale | 91,614 | $4.24M | 0.01% | +1,614+1.8% | Added |