Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 312
- +12 vs. Q2 2023
- Shares held
- 139.7M
- +6.44M (+4.8%) vs. Q2 2023
- Total value
- $6.35B
- +$878.1M (+16.1%) vs. Q2 2023
- New holders
- 39
- 101 more added
- Sold out
- 27
- 103 more reduced
5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Susquehanna International Group, LLP | 88,739 | $4.03M | 0.01% | −78,777−47.0% | Reduced |
| Davenport & Co LLC | 86,877 | $3.94M | 0.03% | −940−1.1% | Reduced |
| Russell Investments Group, Ltd. | 85,995 | $3.90M | 0.01% | −27,335−24.1% | Reduced |
| LPL Financial LLC | 81,816 | $3.71M | 0.00% | −219−0.3% | Reduced |
| Commerce Bank | 77,647 | $3.52M | 0.03% | −10,635−12.0% | Reduced |
| State of New Jersey Common Pension Fund D | 77,261 | $3.50M | 0.01% | −3,172−3.9% | Reduced |
| Marshall Wace, LLP | 68,127 | $3.09M | 0.01% | −936−1.4% | Reduced |
| SEI Investments Co | 64,711 | $2.94M | 0.01% | +49,401+322.7% | Added |
| Van Eck Associates Corp | 64,687 | $2.93M | 0.01% | +33,326+106.3% | Added |
| Treasurer of the State of North Carolina | 62,532 | $2.84M | 0.02% | +310+0.5% | Added |
| UBS Oconnor LLC | 62,059 | $2.81M | 0.05% | −10,000−13.9% | Reduced |
| Schonfeld Strategic Advisors LLC | 61,548 | $2.79M | 0.03% | +22,504+57.6% | Added |
| Janus Henderson Group PLC | 59,806 | $2.71M | 0.00% | +40.0% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.71M | 0.02% | 00.0% | Unchanged |
| Public Employees Retirement System of Ohio | 58,000 | $2.63M | 0.01% | −6,426−10.0% | Reduced |
| Voya Investment Management LLC | 57,673 | $2.62M | 0.00% | −1,823−3.1% | Reduced |
| Erste Asset Management GmbH | 51,300 | $2.37M | 0.04% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 48,618 | $2.21M | 0.02% | +788+1.6% | Added |
| HighVista Strategies LLC | 48,520 | $2.20M | 1.02% | +48,520 | New |
| Boulder Hill Capital Management LP | 46,500 | $2.11M | 1.31% | +46,500 | New |
| Ensign Peak Advisors, Inc | 46,310 | $2.10M | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 45,522 | $2.06M | 0.10% | −3,730−7.6% | Reduced |
| Granite Bay Wealth Management, LLC | 47,579 | $1.97M | 0.02% | +47,579 | New |
| International Biotechnology Trust PLC | 43,000 | $1.95M | 0.66% | 00.0% | Unchanged |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.91M | 0.29% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 41,571 | $1.89M | 0.03% | +22,078+113.3% | Added |
| Nicola Wealth Management Ltd. | 30,000 | $1.84M | 0.20% | +30,000 | New |
| Guggenheim Capital LLC | 40,475 | $1.84M | 0.02% | −11,451−22.1% | Reduced |
| Capital Counsel LLC | 40,230 | $1.82M | 0.10% | 00.0% | Unchanged |
| Comerica Bank | 39,948 | $1.81M | 0.01% | +39,410+7,325.3% | Added |
| Great West Life Assurance Co | 36,801 | $1.67M | 0.00% | +8,758+31.2% | Added |
| Arizona State Retirement System | 36,668 | $1.66M | 0.01% | +530+1.5% | Added |
| Teacher Retirement System of Texas | 36,578 | $1.66M | 0.01% | +1,675+4.8% | Added |
| Profund Advisors LLC | 35,470 | $1.61M | 0.09% | −814−2.2% | Reduced |
| Principal Financial Group Inc | 34,651 | $1.57M | 0.00% | +1,381+4.2% | Added |
| Virginia Retirement Systems Et Al | 32,900 | $1.49M | 0.01% | −1,700−4.9% | Reduced |
| Grandfield & Dodd, LLC | 32,862 | $1.49M | 0.11% | +183+0.6% | Added |
| Estate Counselors, LLC | 32,800 | $1.49M | 0.20% | −310−0.9% | Reduced |
| Janney Montgomery Scott LLC | 29,618 | $1.34M | 0.01% | −1,485−4.8% | Reduced |
| EAM Investors, LLC | 29,262 | $1.33M | 0.26% | +29,262 | New |
| Amalgamated Bank | 29,086 | $1.32M | 0.01% | −373−1.3% | Reduced |
| Bokf, NA | 26,974 | $1.19M | 0.03% | −31,776−54.1% | Reduced |
| Bard Financial Services, Inc. | 25,550 | $1.16M | 0.14% | −5,750−18.4% | Reduced |
| Handelsbanken Fonder AB | 23,811 | $1.08M | 0.01% | −6,900−22.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,339 | $1.06M | 0.00% | +3,327+16.6% | Added |
| Creative Planning | 21,572 | $978.5K | 0.00% | +6,329+41.5% | Added |
| Commonwealth Equity Services, LLC | 21,470 | $974.0K | 0.00% | +897+4.4% | Added |
| Twin Tree Management, LP | 20,441 | $927.2K | 0.03% | +20,441 | New |
| PDT Partners, LLC | 19,537 | $886.2K | 0.11% | +1,039+5.6% | Added |
| Point72 Middle East FZE | 18,313 | $830.7K | 0.05% | +2,009+12.3% | Added |
| Public Employees Retirement Association of Colorado | 17,906 | $812.0K | 0.00% | −1,698−8.7% | Reduced |
| Koss-Olinger Consulting, LLC | 17,907 | $812.0K | 0.12% | 00.0% | Unchanged |
| Mariner, LLC | 17,888 | $811.4K | 0.00% | +514+3.0% | Added |
| Xponance, Inc. | 17,836 | $809.0K | 0.01% | −430−2.4% | Reduced |
| NBT Bank N A | 17,050 | $773.4K | 0.07% | +17,050 | New |
| Campbell & CO Investment Adviser LLC | 16,547 | $750.6K | 0.09% | +16,547 | New |
| XTX Topco Ltd | 16,352 | $741.7K | 0.13% | +16,352 | New |
| Blair William & Co | 16,344 | $741.4K | 0.00% | −40−0.2% | Reduced |
| Natixis Advisors, L.P. | 15,919 | $722.0K | 0.00% | −279−1.7% | Reduced |
| Neuberger Berman Group LLC | 15,534 | $704.6K | 0.00% | +328+2.2% | Added |
| Victory Capital Management Inc | 15,436 | $700.2K | 0.00% | +348+2.3% | Added |
| Tanaka Capital Management Inc | 14,612 | $663.0K | 1.89% | +7,500+105.5% | Added |
| Graham Capital Management, L.P. | 14,488 | $657.2K | 0.02% | +14,488 | New |
| Teachers Retirement System of the State of Kentucky | 14,118 | $640.0K | 0.01% | +14,118 | New |
| Martingale Asset Management L P | 14,034 | $636.6K | 0.01% | 00.0% | Unchanged |
| North Star Asset Management Inc | 13,640 | $618.7K | 0.04% | 00.0% | Unchanged |
| Fred Alger Management, LLC | 13,566 | $615.4K | 0.00% | +13,566 | New |
| Westmount Partners, LLC | 13,462 | $610.6K | 0.27% | 00.0% | Unchanged |
| US Bancorp | 13,358 | $605.9K | 0.00% | −662−4.7% | Reduced |
| Centiva Capital, LP | 13,307 | $603.6K | 0.03% | +13,307 | New |
| Horizon Kinetics Asset Management LLC | 13,000 | $589.7K | 0.01% | 00.0% | Unchanged |
| American Century Companies Inc | 12,982 | $588.9K | 0.00% | +375+3.0% | Added |
| Raymond James Financial Services Advisors, Inc. | 12,257 | $556.0K | 0.00% | −1,885−13.3% | Reduced |
| Bleakley Financial Group, LLC | 12,198 | $553.3K | 0.02% | −340−2.7% | Reduced |
| Sawtooth Solutions, LLC | 12,198 | $553.3K | 0.02% | −267−2.1% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 12,042 | $546.2K | 0.00% | +129+1.1% | Added |
| Brown Advisory Inc | 11,725 | $531.8K | 0.00% | +138+1.2% | Added |
| Advisor Group Holdings, Inc. | 11,448 | $519.2K | 0.00% | +2,687+30.7% | Added |
| Acuta Capital Partners, LLC | 11,300 | $512.6K | 0.37% | +11,300 | New |
| Northwestern Mutual Wealth Management Co | 11,167 | $506.5K | 0.00% | +4,522+68.1% | Added |
| HighTower Advisors, LLC | 11,104 | $506.0K | 0.00% | −145−1.3% | Reduced |
| Plancorp, LLC | 11,155 | $506.0K | 0.03% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 11,096 | $503.0K | 0.04% | +108+1.0% | Added |
| Oppenheimer Asset Management Inc. | 10,968 | $497.5K | 0.01% | −51−0.5% | Reduced |
| Maryland State Retirement & Pension System | 10,950 | $496.7K | 0.01% | 00.0% | Unchanged |
| Captrust Financial Advisors | 10,266 | $465.7K | 0.00% | +939+10.1% | Added |
| Waddell & Associates, LLC | 10,042 | $455.5K | 0.07% | 00.0% | Unchanged |
| Deutsche Bank AG | 9,489 | $430.4K | 0.00% | +63+0.7% | Added |
| ProShare Advisors LLC | 9,370 | $425.0K | 0.00% | +112+1.2% | Added |
| AtonRa Partners | 9,329 | $423.2K | 0.89% | −2,307−19.8% | Reduced |
| Corton Capital Inc. | 8,895 | $403.5K | 0.20% | +1,966+28.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 8,803 | $399.3K | 0.04% | +8,803 | New |
| Nicollet Investment Management, Inc. | 8,668 | $393.0K | 0.18% | −90−1.0% | Reduced |
| Franklin Resources Inc | 8,449 | $383.2K | 0.00% | −722−7.9% | Reduced |
| Vontobel Holding Ltd. | 8,216 | $372.7K | 0.00% | −350−4.1% | Reduced |
| The PNC Financial Services Group, Inc. | 8,176 | $370.9K | 0.00% | −195−2.3% | Reduced |
| Gotham Asset Management, LLC | 8,088 | $366.9K | 0.01% | +23+0.3% | Added |
| MetLife Investment Management | 7,926 | $359.5K | 0.00% | +4+0.1% | Added |
| Midwest Professional Planners, LTD. | 7,825 | $354.9K | 0.16% | +1,232+18.7% | Added |
| Ameriprise Financial Inc | 7,815 | $354.5K | 0.00% | −1,445−15.6% | Reduced |