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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
312
+12 vs. Q2 2023
Shares held
139.7M
+6.44M (+4.8%) vs. Q2 2023
Total value
$6.35B
+$878.1M (+16.1%) vs. Q2 2023
New holders
39
101 more added
Sold out
27
103 more reduced

5 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 312 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ3 2023: $6.35B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2023.

Institutions holding IONS in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Manchester Capital Management LLC5$2270.00%+5New
Cape Investment Advisory, Inc.6$2720.00%00.0%Unchanged
JNBA Financial Advisors7$3180.00%+7New
Whittier Trust Co9$4080.00%+9New
Retirement Group, LLC11$4990.00%00.0%Unchanged
Focused Wealth Management, Inc16$7260.00%00.0%Unchanged
Proequities, Inc.19$8610.00%+19New
Key Financial Inc19$8620.00%00.0%Unchanged
Front Row Advisors LLC20$9070.00%00.0%Unchanged
Rosenberg Matthew Hamilton20$9070.00%00.0%Unchanged
Raffa Wealth Management, LLC28$1.27K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.36K0.00%00.0%Unchanged
Orion Capital Management LLC38$1.72K0.00%+38New
SRS Capital Advisors, Inc.40$1.81K0.00%−58−59.2%Reduced
Bessemer Group Inc52$2.00K0.00%00.0%Unchanged
Cornerstone Planning Group LLC45$2.04K0.00%00.0%Unchanged
Earnest Partners LLC49$2.22K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.50K0.00%00.0%Unchanged
Global Retirement Partners, LLC58$2.53K0.00%00.0%Unchanged
Johnson Midwest Financial, LLC59$2.68K0.01%00.0%Unchanged
Parkside Financial Bank & Trust62$2.81K0.00%00.0%Unchanged
Versant Capital Management, Inc66$2.99K0.00%00.0%Unchanged
Centerpoint Advisors, LLC68$3.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB67$3.04K0.00%+4+6.3%Added
Bell Investment Advisors, Inc71$3.22K0.00%−31−30.4%Reduced
Raleigh Capital Management Inc.72$3.27K0.00%00.0%Unchanged
Baker Avenue Asset Management, LP77$3.49K0.00%00.0%Unchanged
Semmax Financial Advisors Inc.82$3.84K0.00%+82New
Bogart Wealth, LLC85$3.86K0.00%00.0%Unchanged
Legacy Financial Group LLC100$4.54K0.00%+100New
Umb Bank N A101$4.58K0.00%00.0%Unchanged
Colonial Trust Co120$4.85K0.00%00.0%Unchanged
Private Trust Co NA110$4.99K0.00%00.0%Unchanged
Leonteq Securities AG130$5.90K0.00%+130New
Pacifica Partners Inc.150$7.03K0.00%00.0%Unchanged
Carolinas Wealth Consulting LLC161$7.13K0.00%00.0%Unchanged
Clearstead Advisors, LLC185$8.39K0.00%00.0%Unchanged
AllSquare Wealth Management LLC198$8.98K0.01%00.0%Unchanged
GPS Wealth Strategies Group, LLC198$8.98K0.00%+14+7.6%Added
Huntington National Bank199$9.03K0.00%00.0%Unchanged
Quantbot Technologies LP200$9.07K0.00%00.0%Unchanged
Spire Wealth Management210$9.53K0.00%00.0%Unchanged
Farther Finance Advisors, LLC240$10.9K0.00%−7−2.8%Reduced
Covestor Ltd243$11.0K0.01%−3−1.2%Reduced
Washington Trust Advisors, Inc.258$11.7K0.00%00.0%Unchanged
Storebrand Asset Management AS271$12.3K0.00%00.0%Unchanged
Lindbrook Capital, LLC308$14.0K0.00%−38−11.0%Reduced
Group One Trading, L.P.318$14.4K0.00%+318New
EverSource Wealth Advisors, LLC340$15.4K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc341$15.5K0.00%00.0%Unchanged
Signaturefd, LLC366$16.6K0.00%−110−23.1%Reduced
Banque Cantonale Vaudoise400$18.0K0.00%00.0%Unchanged
Global Trust Asset Management, LLC474$21.5K0.01%+75+18.8%Added
Riverview Trust Co476$21.6K0.02%00.0%Unchanged
Riggs Asset Managment Co. Inc.500$22.7K0.01%00.0%Unchanged
Steward Partners Investment Advisory, LLC506$23.0K0.00%+240+90.2%Added
AlphaMark Advisors, LLC500$23.0K0.01%00.0%Unchanged
Daiwa Securities Group Inc.515$23.0K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC555$25.2K0.00%00.0%Unchanged
Quadrant Capital Group LLC588$26.7K0.00%00.0%Unchanged
Laurel Wealth Advisors LLC600$27.2K0.01%00.0%Unchanged
Parallel Advisors, LLC671$30.4K0.00%−40−5.6%Reduced
Institutional & Family Asset Management, LLC729$33.1K0.01%00.0%Unchanged
Glassman Wealth Services739$33.5K0.01%00.0%Unchanged
Ronald Blue Trust, Inc.849$35.0K0.00%00.0%Unchanged
Archer Investment Corp850$38.6K0.01%00.0%Unchanged
Peoples Bank850$38.6K0.03%+850New
Tower Research Capital LLC (TRC)896$40.6K0.00%−4,992−84.8%Reduced
Harbour Investments, Inc.900$40.8K0.00%00.0%Unchanged
Allworth Financial LP901$40.9K0.00%+42+4.9%Added
GWM Advisors LLC1,114$50.5K0.00%+1,093+5,204.8%Added
IFP Advisors, Inc1,141$51.8K0.00%−14−1.2%Reduced
Twin Lakes Capital Management, LLC1,500$68.0K0.05%00.0%Unchanged
Quarry LP1,500$68.0K0.04%+1,500New
Itau Unibanco Holding S.A.1,807$82.0K0.00%−8−0.4%Reduced
Horizon Investments, LLC1,899$86.1K0.00%+163+9.4%Added
CWM, LLC2,206$100.0K0.00%−22−1.0%Reduced
American International Group, Inc.2,298$104.2K0.00%−157−6.4%Reduced
Fifth Third Bancorp2,500$113.4K0.00%00.0%Unchanged
Ci Investments Inc.2,524$114.0K0.00%−384−13.2%Reduced
KBC Group NV2,669$121.0K0.00%+1,291+93.7%Added
Icon Wealth Partners, LLC2,724$123.6K0.01%−13−0.5%Reduced
China Universal Asset Management Co., Ltd.3,670$166.5K0.05%+1,795+95.7%Added
Toroso Investments, LLC4,427$200.8K0.01%+4,427New
Cetera Advisor Networks LLC4,438$201.3K0.00%−737−14.2%Reduced
Wealthcare Advisory Partners LLC4,613$209.2K0.01%+4,613New
Mitchell & Pahl Private Wealth, LLC4,622$209.7K0.12%+4,622New
Prospera Financial Services Inc4,753$215.6K0.01%+4,753New
Arden Trust Co4,792$217.4K0.04%−462−8.8%Reduced
M&T Bank Corp4,812$218.2K0.00%−348−6.7%Reduced
Sherbrooke Park Advisers LLC4,938$224.0K0.07%+4,938New
Bridgefront Capital, LLC4,948$224.4K0.16%+4,948New
Kestra Advisory Services, LLC4,978$225.8K0.00%−220−4.2%Reduced
Beaird Harris Wealth Management, LLC5,000$226.8K0.03%00.0%Unchanged
Mercer Global Advisors Inc5,096$231.0K0.00%−267−5.0%Reduced
Buckingham Strategic Wealth, LLC5,170$234.5K0.00%+45+0.9%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.5,195$235.6K0.00%+95+1.9%Added
Two Sigma Securities, LLC5,344$242.4K0.01%+5,344New
Perkins Capital Management Inc5,550$252.0K0.25%−100−1.8%Reduced
Vident Advisory, LLC5,586$253.4K0.01%+5,586New