Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 7 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 365
- +57 vs. Q3 2023
- Shares held
- 142.5M
- +2.89M (+2.1%) vs. Q3 2023
- Total value
- $7.21B
- +$870.9M (+13.7%) vs. Q3 2023
- New holders
- 85
- 108 more added
- Sold out
- 28
- 116 more reduced
4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 21,520,872 | $1.09B | 0.08% | +21,950+0.1% | Added |
| Vanguard Group Inc | 14,203,481 | $718.6M | 0.02% | −298,544−2.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 13,201,453 | $667.9M | 0.43% | +78,398+0.6% | Added |
| BlackRock Inc. | 9,057,530 | $458.2M | 0.01% | −57,097−0.6% | Reduced |
| Bellevue Group AG | 8,713,987 | $440.8M | 6.74% | −519,713−5.6% | Reduced |
| Clearbridge Investments, LLC | 4,707,480 | $238.2M | 0.20% | −133,215−2.8% | Reduced |
| Wellington Management Group LLP | 4,616,978 | $233.6M | 0.04% | +2,856,353+162.2% | Added |
| Price T Rowe Associates Inc | 4,255,074 | $215.3M | 0.03% | +497,077+13.2% | Added |
| State Street Corp | 4,008,797 | $202.8M | 0.01% | +53,768+1.4% | Added |
| Pictet Asset Management Holding SA | 3,518,317 | $178.0M | 0.20% | +277,383+8.6% | Added |
| Tweedy, Browne Co LLC | 3,454,676 | $174.8M | 8.53% | −55,497−1.6% | Reduced |
| Macquarie Group Ltd | 3,088,235 | $156.2M | 0.18% | +152,311+5.2% | Added |
| BVF Inc | 2,428,613 | $122.9M | 3.07% | −1,576,000−39.4% | Reduced |
| Geode Capital Management, LLC | 2,275,931 | $115.2M | 0.01% | +81,200+3.7% | Added |
| OrbiMed Advisors LLC | 2,064,797 | $104.5M | 2.09% | −104,703−4.8% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,905,056 | $96.4M | 0.57% | −461,311−19.5% | Reduced |
| Farallon Capital Management, L.L.C. | 1,555,020 | $78.7M | 0.49% | +828,020+113.9% | Added |
| Adage Capital Partners GP, L.L.C. | 1,385,300 | $70.1M | 0.15% | +318,300+29.8% | Added |
| Charles Schwab Investment Management Inc | 1,275,319 | $64.5M | 0.02% | +33,012+2.7% | Added |
| Deep Track Capital, LP | 1,249,068 | $63.2M | 2.21% | −1,585,001−55.9% | Reduced |
| Norges Bank | 1,171,936 | $59.3M | 0.01% | +18,010+1.6% | Added |
| First Trust Advisors LP | 1,097,730 | $55.5M | 0.06% | −37,249−3.3% | Reduced |
| Morgan Stanley | 1,090,263 | $55.2M | 0.00% | +56,859+5.5% | Added |
| Point72 Asset Management, L.P. | 968,800 | $49.0M | 0.15% | +827,300+584.7% | Added |
| TD Asset Management Inc | 956,852 | $48.4M | 0.05% | +58,000+6.5% | Added |
| JPMorgan Chase & Co | 941,032 | $47.6M | 0.00% | +39,975+4.4% | Added |
| Millennium Management LLC | 890,325 | $45.0M | 0.04% | +453,202+103.7% | Added |
| Camber Capital Management LP | 865,000 | $43.8M | 1.53% | −1,385,000−61.6% | Reduced |
| Capital World Investors | 839,463 | $42.5M | 0.01% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 801,448 | $40.5M | 0.10% | +325,391+68.4% | Added |
| Two Sigma Advisers, LP | 777,011 | $39.3M | 0.09% | +172,700+28.6% | Added |
| Royal Bank of Canada | 774,246 | $39.2M | 0.01% | +110,802+16.7% | Added |
| Northern Trust Corp | 687,986 | $34.8M | 0.01% | −2,738−0.4% | Reduced |
| Barclays PLC | 644,508 | $32.6M | 0.02% | +4,955+0.8% | Added |
| Bank of New York Mellon Corp | 641,063 | $32.4M | 0.01% | +13,904+2.2% | Added |
| Candriam Luxembourg S.C.A. | 629,067 | $31.8M | 0.22% | +80,000+14.6% | Added |
| Wells Fargo & Company | 594,250 | $30.1M | 0.01% | −23,680−3.8% | Reduced |
| Jacobs Levy Equity Management, Inc | 509,533 | $25.8M | 0.13% | +136,416+36.6% | Added |
| Nomura Holdings Inc | 489,189 | $24.7M | 0.22% | +29,878+6.5% | Added |
| AXA S.A. | 464,741 | $23.5M | 0.08% | −16,841−3.5% | Reduced |
| Pinnacle Associates Ltd | 458,979 | $23.2M | 0.39% | −4,056−0.9% | Reduced |
| Bank of America Corp | 455,078 | $23.0M | 0.00% | −80,966−15.1% | Reduced |
| Goldman Sachs Group Inc | 381,382 | $19.3M | 0.00% | +43,555+12.9% | Added |
| Groupama Asset Managment | 357,036 | $18.1M | 0.47% | +357,036 | New |
| First Turn Management, LLC | 356,679 | $18.0M | 2.59% | +356,679 | New |
| BNP Paribas Arbitrage, SA | 354,955 | $18.0M | 0.03% | −55,719−13.6% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 339,667 | $17.2M | 0.05% | +339,667 | New |
| Eversept Partners, LP | 324,654 | $16.4M | 1.61% | +72,208+28.6% | Added |
| Nuveen Asset Management, LLC | 324,006 | $16.4M | 0.01% | +14,862+4.8% | Added |
| Schonfeld Strategic Advisors LLC | 313,274 | $15.8M | 0.13% | +251,726+409.0% | Added |
| C WorldWide Group Holding A/S | 300,000 | $15.2M | 0.20% | +300,000 | New |
| Baillie Gifford & Co | 298,483 | $15.1M | 0.01% | −18,146−5.7% | Reduced |
| Amundi | 272,650 | $14.4M | 0.01% | +146,986+117.0% | Added |
| Liontrust Investment Partners LLP | 283,981 | $14.4M | 0.21% | −26,045−8.4% | Reduced |
| CI Private Wealth, LLC | 267,312 | $13.5M | 0.02% | −39,678−12.9% | Reduced |
| Voloridge Investment Management, LLC | 264,121 | $13.4M | 0.05% | +264,121 | New |
| Manufacturers Life Insurance Company, The | 260,702 | $13.2M | 0.01% | +31,025+13.5% | Added |
| Alliancebernstein L.P. | 257,320 | $13.0M | 0.01% | −47,198−15.5% | Reduced |
| Swiss National Bank | 254,300 | $12.9M | 0.01% | −28,800−10.2% | Reduced |
| Citadel Advisors LLC | 252,528 | $12.8M | 0.01% | −283,390−52.9% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 252,459 | $12.8M | 0.01% | −40,014−13.7% | Reduced |
| Nikko Asset Management Americas, Inc. | 252,459 | $12.8M | 0.12% | −40,014−13.7% | Reduced |
| Stifel Financial Corp | 246,029 | $12.4M | 0.02% | −174−0.1% | Reduced |
| Kennedy Capital Management, Inc. | 228,425 | $11.6M | 0.25% | −10,210−4.3% | Reduced |
| Privium Fund Management B.V. | 217,493 | $11.5M | 3.20% | −11,000−4.8% | Reduced |
| Bank of Montreal | 223,389 | $11.3M | 0.01% | −3,432−1.5% | Reduced |
| Parkman Healthcare Partners LLC | 211,400 | $10.7M | 1.51% | +51,897+32.5% | Added |
| California Public Employees Retirement System | 209,436 | $10.6M | 0.01% | −445,935−68.0% | Reduced |
| Altrinsic Global Advisors LLC | 209,152 | $10.6M | 0.45% | −83,032−28.4% | Reduced |
| Invesco Ltd. | 205,901 | $10.4M | 0.00% | +74,734+57.0% | Added |
| Jefferies Financial Group Inc. | 202,300 | $10.2M | 0.16% | +42,090+26.3% | Added |
| Tang Capital Management LLC | 200,000 | $10.1M | 0.93% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 199,477 | $10.1M | 0.12% | +199,477 | New |
| Rhumbline Advisers | 199,416 | $10.1M | 0.01% | +1,956+1.0% | Added |
| Sicart Associates LLC | 194,293 | $9.83M | 3.76% | −8,839−4.4% | Reduced |
| Credit Suisse AG | 189,722 | $9.60M | 0.01% | −40,621−17.6% | Reduced |
| Superstring Capital Management LP | 189,618 | $9.59M | 6.85% | +189,618 | New |
| UBS Asset Management Americas Inc | 186,327 | $9.43M | 0.00% | +9,213+5.2% | Added |
| Assenagon Asset Management S.A. | 184,401 | $9.33M | 0.03% | +184,401 | New |
| Rafferty Asset Management, LLC | 184,396 | $9.33M | 0.04% | −31,575−14.6% | Reduced |
| Raymond James & Associates | 183,676 | $9.29M | 0.01% | −10,953−5.6% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 169,678 | $8.58M | 0.15% | +169,678 | New |
| Tocqueville Asset Management L.P. | 159,780 | $8.08M | 0.15% | −1,950−1.2% | Reduced |
| UBS Group AG | 159,739 | $8.08M | 0.00% | +50,705+46.5% | Added |
| Russell Investments Group, Ltd. | 157,802 | $7.98M | 0.01% | +71,807+83.5% | Added |
| Legal & General Group Plc | 155,348 | $7.86M | 0.00% | −9,687−5.9% | Reduced |
| Jane Street Group, LLC | 154,164 | $7.80M | 0.01% | −99,327−39.2% | Reduced |
| State Board of Administration of Florida Retirement System | 151,055 | $7.64M | 0.02% | +670.0% | Added |
| Sonora Investment Management Group, LLC | 149,338 | $7.56M | 0.61% | +888+0.6% | Added |
| BLB&B Advisors, LLC | 147,100 | $7.44M | 0.47% | −550−0.4% | Reduced |
| Sector Gamma AS | 145,012 | $7.34M | 1.78% | −20,604−12.4% | Reduced |
| Hudson Bay Capital Management LP | 145,000 | $7.34M | 0.06% | −45,000−23.7% | Reduced |
| Verition Fund Management LLC | 142,854 | $7.23M | 0.07% | +6,823+5.0% | Added |
| Swedbank AB | 140,998 | $7.13M | 0.01% | +4,059+3.0% | Added |
| California State Teachers Retirement System | 138,532 | $7.01M | 0.01% | −7,050−4.8% | Reduced |
| Standard Life Aberdeen plc | 136,419 | $6.90M | 0.01% | +136,419 | New |
| Senator Investment Group LP | 135,000 | $6.83M | 0.29% | +135,000 | New |
| Marshall Wace, LLP | 133,549 | $6.76M | 0.01% | +65,422+96.0% | Added |
| Envestnet Asset Management Inc | 133,484 | $6.75M | 0.00% | +6,748+5.3% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 127,954 | $6.47M | 0.03% | −1,858−1.4% | Reduced |