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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
365
+57 vs. Q3 2023
Shares held
142.5M
+2.89M (+2.1%) vs. Q3 2023
Total value
$7.21B
+$870.9M (+13.7%) vs. Q3 2023
New holders
85
108 more added
Sold out
28
116 more reduced

4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 365 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ4 2023: $7.21B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2023.

Institutions holding IONS in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Quest Partners LLC1$510.00%+1New
Cape Investment Advisory, Inc.2$1010.00%−4−66.7%Reduced
Tucker Asset Management LLC3$1520.00%+3New
Fairfield, Bush & Co.4$2020.00%+4New
Manchester Capital Management LLC5$2530.00%00.0%Unchanged
Assetmark, Inc7$3540.00%+7New
JNBA Financial Advisors7$3550.00%00.0%Unchanged
Private Wealth Management Group, LLC10$5060.00%+10New
Retirement Group, LLC11$5560.00%00.0%Unchanged
Fortitude Family Office, LLC14$7080.00%+14New
Focused Wealth Management, Inc16$8090.00%00.0%Unchanged
Key Financial Inc19$9610.00%00.0%Unchanged
Proequities, Inc.19$9610.00%00.0%Unchanged
Avion Wealth25$1.00K0.00%+25New
Front Row Advisors LLC20$1.01K0.00%00.0%Unchanged
Rosenberg Matthew Hamilton20$1.01K0.00%00.0%Unchanged
First Pacific Financial20$1.01K0.00%+20New
Quent Capital, LLC21$1.06K0.00%+21New
Raffa Wealth Management, LLC28$1.42K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.52K0.00%00.0%Unchanged
CVA Family Office, LLC30$1.52K0.00%+30New
Orion Capital Management LLC38$1.92K0.00%00.0%Unchanged
SOA Wealth Advisors, LLC.50$2.53K0.00%+50New
Blume Capital Management, Inc.55$2.78K0.00%00.0%Unchanged
Rockbridge Investment Management, LCC58$2.94K0.00%+58New
Versant Capital Management, Inc59$2.98K0.00%−7−10.6%Reduced
Bessemer Group Inc52$3.00K0.00%00.0%Unchanged
Parkside Financial Bank & Trust62$3.14K0.00%00.0%Unchanged
Massmutual Trust Co FSB67$3.39K0.00%00.0%Unchanged
Bell Investment Advisors, Inc71$3.59K0.00%00.0%Unchanged
Raleigh Capital Management Inc.72$3.64K0.00%00.0%Unchanged
Semmax Financial Advisors Inc.82$3.97K0.00%00.0%Unchanged
DAGCO, Inc.80$4.05K0.00%+80New
Dynamic Wealth Strategies, LLC80$4.05K0.00%+80New
SRS Capital Advisors, Inc.84$4.25K0.00%+44+110.0%Added
Bogart Wealth, LLC85$4.30K0.00%00.0%Unchanged
Global Retirement Partners, LLC91$4.64K0.00%+33+56.9%Added
Creekmur Asset Management LLC100$5.06K0.00%+100New
Cornerstone Planning Group LLC109$5.51K0.00%+64+142.2%Added
Garner Asset Management Corp115$5.72K0.00%+115New
Sachetta, LLC115$5.82K0.00%+115New
Ronald Blue Trust, Inc.137$6.00K0.00%−712−83.9%Reduced
Colonial Trust Co120$6.06K0.00%00.0%Unchanged
Spire Wealth Management125$6.37K0.00%−85−40.5%Reduced
Walleye Trading LLC148$7.49K0.00%+148New
Pacifica Partners Inc.150$7.50K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC198$10.0K0.00%00.0%Unchanged
AllSquare Wealth Management LLC198$10.0K0.01%00.0%Unchanged
Quarry LP200$10.1K0.01%−1,300−86.7%Reduced
SYSTM Wealth Solutions LLC204$10.3K0.00%+204New
Covestor Ltd243$12.0K0.01%00.0%Unchanged
Riggs Asset Managment Co. Inc.250$12.6K0.00%−250−50.0%Reduced
Washington Trust Advisors, Inc.258$13.1K0.00%00.0%Unchanged
Storebrand Asset Management AS271$13.7K0.00%00.0%Unchanged
Huntington National Bank289$14.6K0.00%+90+45.2%Added
Advisors Asset Management, Inc.303$15.3K0.00%+303New
EverSource Wealth Advisors, LLC340$17.2K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc341$17.2K0.00%00.0%Unchanged
Private Trust Co NA367$18.6K0.00%+257+233.6%Added
Lindbrook Capital, LLC393$19.9K0.00%+85+27.6%Added
Banque Cantonale Vaudoise400$20.0K0.00%00.0%Unchanged
ORG Partners LLC400$20.2K0.00%+400New
Whittier Trust Co462$23.4K0.00%+453+5,033.3%Added
Global Trust Asset Management, LLC474$24.0K0.01%00.0%Unchanged
Steward Partners Investment Advisory, LLC481$24.3K0.00%−25−4.9%Reduced
AlphaMark Advisors, LLC500$25.0K0.01%00.0%Unchanged
Clearstead Advisors, LLC495$25.0K0.00%+310+167.6%Added
Pingora Partners LLC500$25.3K0.02%+500New
Signaturefd, LLC501$25.3K0.00%+135+36.9%Added
GAMMA Investing LLC500$25.7K0.01%+500New
Advisory Services Network, LLC519$26.3K0.00%+519New
Allspring Global Investments Holdings, LLC555$28.1K0.00%00.0%Unchanged
Parallel Advisors, LLC565$28.6K0.00%−106−15.8%Reduced
Farther Finance Advisors, LLC569$28.8K0.00%+329+137.1%Added
Daiwa Securities Group Inc.587$30.0K0.00%+72+14.0%Added
Laurel Wealth Advisors LLC600$30.4K0.01%00.0%Unchanged
Quadrant Capital Group LLC671$33.9K0.00%+83+14.1%Added
Tennessee Valley Asset Management Partners673$34.0K0.01%+673New
Glassman Wealth Services686$34.7K0.00%−53−7.2%Reduced
Global X Japan Co., Ltd.716$36.2K0.02%+716New
Institutional & Family Asset Management, LLC729$36.9K0.01%00.0%Unchanged
Allworth Financial LP776$39.3K0.00%−125−13.9%Reduced
nVerses Capital, LLC–$40.5K0.11%–New
Archer Investment Corp850$43.0K0.01%00.0%Unchanged
EntryPoint Capital, LLC878$44.4K0.04%+878New
Harbour Investments, Inc.900$45.5K0.00%00.0%Unchanged
Group One Trading, L.P.1,018$51.5K0.00%+700+220.1%Added
IFP Advisors, Inc1,070$54.1K0.00%−71−6.2%Reduced
Itau Unibanco Holding S.A.1,429$72.3K0.00%−378−20.9%Reduced
Twin Lakes Capital Management, LLC1,500$75.9K0.05%00.0%Unchanged
Horizon Investments, LLC1,927$97.5K0.00%+28+1.5%Added
GWM Advisors LLC2,088$105.6K0.00%+974+87.4%Added
CWM, LLC2,197$111.0K0.00%−9−0.4%Reduced
American International Group, Inc.2,237$113.2K0.00%−61−2.7%Reduced
Torno Capital, LLC2,500$126.5K0.13%+2,500New
Icon Wealth Advisors, LLC2,537$128.3K0.01%+2,537New
KBC Group NV2,669$135.0K0.00%00.0%Unchanged
Natixis2,878$145.6K0.00%+2,878New
Tower Research Capital LLC (TRC)3,360$170.0K0.00%+2,464+275.0%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.3,693$190.5K0.00%−1,502−28.9%Reduced