Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 365
- +57 vs. Q3 2023
- Shares held
- 142.5M
- +2.89M (+2.1%) vs. Q3 2023
- Total value
- $7.21B
- +$870.9M (+13.7%) vs. Q3 2023
- New holders
- 85
- 108 more added
- Sold out
- 28
- 116 more reduced
4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Dimensional Fund Advisors LP | 125,217 | $6.33M | 0.00% | −66,943−34.8% | Reduced |
| Granite Investment Partners, LLC | 119,946 | $6.07M | 0.24% | +119,946 | New |
| D. E. Shaw & Co., Inc. | 119,158 | $6.03M | 0.01% | −242,887−67.1% | Reduced |
| Trexquant Investment LP | 112,987 | $5.72M | 0.13% | −70,362−38.4% | Reduced |
| Renaissance Technologies LLC | 112,414 | $5.69M | 0.01% | −157,386−58.3% | Reduced |
| Parkwood LLC | 108,554 | $5.49M | 0.88% | +108,554 | New |
| Peregrine Capital Management LLC | 107,824 | $5.45M | 0.16% | −18,569−14.7% | Reduced |
| New York State Common Retirement Fund | 105,329 | $5.33M | 0.01% | −12,900−10.9% | Reduced |
| State of Wisconsin Investment Board | 103,565 | $5.24M | 0.01% | −2,200−2.1% | Reduced |
| Citigroup Inc | 100,245 | $5.07M | 0.01% | −89,375−47.1% | Reduced |
| DekaBank Deutsche Girozentrale | 91,614 | $4.61M | 0.01% | 00.0% | Unchanged |
| LPL Financial LLC | 87,299 | $4.42M | 0.00% | +5,483+6.7% | Added |
| Davenport & Co LLC | 86,328 | $4.37M | 0.03% | −549−0.6% | Reduced |
| State of New Jersey Common Pension Fund D | 81,847 | $4.14M | 0.01% | +4,586+5.9% | Added |
| Man Group plc | 78,475 | $3.97M | 0.01% | – | – |
| Voya Investment Management LLC | 76,911 | $3.89M | 0.00% | +19,238+33.4% | Added |
| Nicola Wealth Management Ltd. | 56,000 | $3.75M | 0.39% | +26,000+86.7% | Added |
| Aigen Investment Management, LP | 73,720 | $3.73M | 0.67% | +73,720 | New |
| Cinctive Capital Management LP | 73,256 | $3.71M | 0.26% | +73,256 | New |
| SEI Investments Co | 70,173 | $3.55M | 0.01% | +5,462+8.4% | Added |
| Commerce Bank | 67,017 | $3.39M | 0.02% | −10,630−13.7% | Reduced |
| Van Eck Associates Corp | 65,831 | $3.33M | 0.01% | +1,144+1.8% | Added |
| Treasurer of the State of North Carolina | 63,152 | $3.19M | 0.02% | +620+1.0% | Added |
| Lisanti Capital Growth, LLC | 62,415 | $3.16M | 0.74% | +62,415 | New |
| Jump Financial, LLC | 61,739 | $3.12M | 0.10% | −57,661−48.3% | Reduced |
| Janus Henderson Group PLC | 59,703 | $3.02M | 0.00% | −103−0.2% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $3.02M | 0.02% | 00.0% | Unchanged |
| Public Employees Retirement System of Ohio | 59,630 | $3.02M | 0.01% | +1,630+2.8% | Added |
| Squarepoint Ops LLC | 59,204 | $3.00M | 0.01% | −80,316−57.6% | Reduced |
| HighVista Strategies LLC | 57,348 | $2.90M | 1.05% | +8,828+18.2% | Added |
| Susquehanna International Group, LLP | 54,133 | $2.74M | 0.00% | −34,606−39.0% | Reduced |
| Cowen and Company, LLC | 51,415 | $2.60M | 0.17% | +51,415 | New |
| Erste Asset Management GmbH | 51,300 | $2.59M | 0.04% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 48,807 | $2.47M | 0.02% | +189+0.4% | Added |
| Ensign Peak Advisors, Inc | 46,310 | $2.34M | 0.00% | 00.0% | Unchanged |
| Schroder Investment Management Group | 43,000 | $2.18M | 0.00% | +43,000 | New |
| NJ State Employees Deferred Compensation Plan | 42,000 | $2.12M | 0.29% | 00.0% | Unchanged |
| Great West Life Assurance Co | 40,781 | $2.05M | 0.00% | +3,980+10.8% | Added |
| Capital Counsel LLC | 40,080 | $2.03M | 0.10% | −150−0.4% | Reduced |
| Comerica Bank | 39,614 | $2.00M | 0.01% | −334−0.8% | Reduced |
| Arizona State Retirement System | 36,059 | $1.82M | 0.01% | −609−1.7% | Reduced |
| Deutsche Bank AG | 35,702 | $1.81M | 0.00% | +26,213+276.2% | Added |
| Guggenheim Capital LLC | 33,151 | $1.68M | 0.01% | −7,324−18.1% | Reduced |
| Grandfield & Dodd, LLC | 33,104 | $1.67M | 0.12% | +242+0.7% | Added |
| Estate Counselors, LLC | 32,800 | $1.66M | 0.20% | 00.0% | Unchanged |
| Principal Financial Group Inc | 31,139 | $1.58M | 0.00% | −3,512−10.1% | Reduced |
| Nicholas Investment Partners, LP | 30,445 | $1.54M | 0.18% | +30,445 | New |
| Teacher Retirement System of Texas | 29,844 | $1.51M | 0.01% | −6,734−18.4% | Reduced |
| Twinbeech Capital LP | 29,729 | $1.50M | 0.02% | +29,729 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 29,440 | $1.49M | 0.01% | +6,101+26.1% | Added |
| Profund Advisors LLC | 29,073 | $1.47M | 0.06% | −6,397−18.0% | Reduced |
| Amalgamated Bank | 28,995 | $1.47M | 0.01% | −91−0.3% | Reduced |
| Engineers Gate Manager LP | 28,877 | $1.46M | 0.04% | +28,877 | New |
| UBS Oconnor LLC | 28,624 | $1.45M | 0.05% | −33,435−53.9% | Reduced |
| Janney Montgomery Scott LLC | 28,379 | $1.44M | 0.00% | −1,239−4.2% | Reduced |
| Victory Capital Management Inc | 27,793 | $1.41M | 0.00% | +12,357+80.1% | Added |
| Handelsbanken Fonder AB | 27,011 | $1.37M | 0.01% | +3,200+13.4% | Added |
| Ameriprise Financial Inc | 25,625 | $1.30M | 0.00% | +17,810+227.9% | Added |
| Creative Planning | 25,299 | $1.28M | 0.00% | +3,727+17.3% | Added |
| STRS Ohio | 24,779 | $1.25M | 0.01% | +24,779 | New |
| HealthInvest Partners AB | 24,243 | $1.23M | 0.96% | +24,243 | New |
| Fred Alger Management, LLC | 24,054 | $1.22M | 0.01% | +10,488+77.3% | Added |
| ExodusPoint Capital Management, LP | 23,484 | $1.19M | 0.01% | +23,484 | New |
| Commonwealth Equity Services, LLC | 21,462 | $1.09M | 0.00% | −80.0% | Reduced |
| Mariner, LLC | 20,672 | $1.05M | 0.00% | +2,784+15.6% | Added |
| Point72 Hong Kong Ltd | 20,015 | $1.01M | 0.06% | +20,015 | New |
| Bank Julius Baer & Co. Ltd, Zurich | 19,050 | $963.7K | 0.00% | +19,050 | New |
| Advisor Group Holdings, Inc. | 18,910 | $956.4K | 0.00% | +7,462+65.2% | Added |
| Algert Global LLC | 17,412 | $880.9K | 0.04% | −28,110−61.8% | Reduced |
| Natixis Advisors, L.P. | 17,313 | $875.0K | 0.00% | +1,394+8.8% | Added |
| NBT Bank N A | 17,050 | $862.6K | 0.07% | 00.0% | Unchanged |
| Xponance, Inc. | 16,693 | $844.5K | 0.01% | −1,143−6.4% | Reduced |
| Blair William & Co | 16,628 | $841.2K | 0.00% | +284+1.7% | Added |
| China Universal Asset Management Co., Ltd. | 16,598 | $839.7K | 0.16% | +12,928+352.3% | Added |
| Public Employees Retirement Association of Colorado | 16,574 | $838.0K | 0.00% | −1,332−7.4% | Reduced |
| Calamos Advisors LLC | 16,379 | $828.6K | 0.00% | +16,379 | New |
| Two Sigma Securities, LLC | 15,404 | $779.3K | 0.04% | +10,060+188.2% | Added |
| Tanaka Capital Management Inc | 14,612 | $739.0K | 1.81% | 00.0% | Unchanged |
| Friedenthal Financial | 14,225 | $719.6K | 0.47% | +14,225 | New |
| Teachers Retirement System of the State of Kentucky | 14,118 | $714.0K | 0.01% | 00.0% | Unchanged |
| Bard Financial Services, Inc. | 14,100 | $713.3K | 0.08% | −11,450−44.8% | Reduced |
| Neuberger Berman Group LLC | 13,998 | $708.2K | 0.00% | −1,536−9.9% | Reduced |
| Westmount Partners, LLC | 13,872 | $701.8K | 0.29% | +410+3.0% | Added |
| Franklin Resources Inc | 13,705 | $693.3K | 0.00% | +5,256+62.2% | Added |
| North Star Asset Management Inc | 13,650 | $690.6K | 0.04% | +10+0.1% | Added |
| Raymond James Financial Services Advisors, Inc. | 13,647 | $690.4K | 0.00% | +1,390+11.3% | Added |
| Martingale Asset Management L P | 13,312 | $673.5K | 0.01% | −722−5.1% | Reduced |
| American Century Companies Inc | 13,216 | $668.6K | 0.00% | +234+1.8% | Added |
| Chartwell Investment Partners, LLC | 12,982 | $657.0K | 0.02% | +12,982 | New |
| Quantbot Technologies LP | 12,703 | $642.6K | 0.04% | +12,503+6,251.5% | Added |
| Graham Capital Management, L.P. | 12,525 | $633.6K | 0.02% | −1,963−13.5% | Reduced |
| Horizon Kinetics Asset Management LLC | 12,476 | $631.2K | 0.01% | −524−4.0% | Reduced |
| Granite Bay Wealth Management, LLC | 13,579 | $626.0K | 0.01% | −34,000−71.5% | Reduced |
| Sawtooth Solutions, LLC | 12,239 | $619.2K | 0.02% | +41+0.3% | Added |
| Bleakley Financial Group, LLC | 12,239 | $619.2K | 0.02% | +41+0.3% | Added |
| Pathstone Holdings, LLC | 11,882 | $611.2K | 0.00% | +11,882 | New |
| US Bancorp | 11,935 | $603.8K | 0.00% | −1,423−10.7% | Reduced |
| Gsa Capital Partners LLP | 11,680 | $591.0K | 0.05% | +11,680 | New |
| Brown Advisory Inc | 11,544 | $584.0K | 0.00% | −181−1.5% | Reduced |
| Corton Capital Inc. | 11,476 | $580.6K | 0.18% | +2,581+29.0% | Added |