Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 365
- +57 vs. Q3 2023
- Shares held
- 142.5M
- +2.89M (+2.1%) vs. Q3 2023
- Total value
- $7.21B
- +$870.9M (+13.7%) vs. Q3 2023
- New holders
- 85
- 108 more added
- Sold out
- 28
- 116 more reduced
4 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Plancorp, LLC | 11,155 | $564.3K | 0.03% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 11,146 | $563.9K | 0.00% | −21−0.2% | Reduced |
| HighTower Advisors, LLC | 11,086 | $560.0K | 0.00% | −18−0.2% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 11,034 | $558.0K | 0.00% | +4,387+66.0% | Added |
| Maryland State Retirement & Pension System | 10,950 | $554.0K | 0.01% | 00.0% | Unchanged |
| Oppenheimer Asset Management Inc. | 10,549 | $533.7K | 0.01% | −419−3.8% | Reduced |
| Captrust Financial Advisors | 10,108 | $511.4K | 0.00% | −158−1.5% | Reduced |
| Point72 Middle East FZE | 9,983 | $505.0K | 0.04% | −8,330−45.5% | Reduced |
| Truist Financial Corp | 9,965 | $504.1K | 0.00% | +9,965 | New |
| E Fund Management Co., Ltd. | 9,865 | $499.1K | 0.03% | −1,231−11.1% | Reduced |
| Nicollet Investment Management, Inc. | 9,776 | $495.0K | 0.20% | +1,108+12.8% | Added |
| Teza Capital Management LLC | 9,733 | $492.4K | 0.08% | +9,733 | New |
| Simplex Trading, LLC | 9,545 | $482.0K | 0.02% | +9,545 | New |
| Wolverine Trading, LLC | 9,495 | $480.4K | 0.00% | +9,495 | New |
| Fifth Third Bancorp | 9,282 | $469.6K | 0.00% | +6,782+271.3% | Added |
| Fox Run Management, L.L.C. | 9,271 | $469.0K | 0.12% | +9,271 | New |
| ProShare Advisors LLC | 9,167 | $463.8K | 0.00% | −203−2.2% | Reduced |
| PEAK6 Investments LLC | 9,001 | $455.4K | 0.02% | +2,499+38.4% | Added |
| NEOS Investment Management LLC | 8,906 | $450.6K | 0.04% | +8,906 | New |
| Midwest Professional Planners, LTD. | 8,519 | $431.0K | 0.17% | +694+8.9% | Added |
| AtonRa Partners | 8,396 | $424.8K | 0.85% | −933−10.0% | Reduced |
| The PNC Financial Services Group, Inc. | 8,378 | $423.8K | 0.00% | +202+2.5% | Added |
| JustInvest LLC | 8,342 | $422.0K | 0.01% | +1,564+23.1% | Added |
| Vontobel Holding Ltd. | 8,210 | $415.3K | 0.00% | −6−0.1% | Reduced |
| Handelsinvest Investeringsforvaltning | 8,033 | $406.0K | 0.17% | +8,033 | New |
| Stephens Inc | 7,955 | $402.4K | 0.01% | +470+6.3% | Added |
| Utah Retirement Systems | 7,900 | $399.7K | 0.01% | +200+2.6% | Added |
| MetLife Investment Management | 7,817 | $395.5K | 0.00% | −109−1.4% | Reduced |
| Wrapmanager Inc | 7,404 | $374.6K | 0.11% | −123−1.6% | Reduced |
| Gotham Asset Management, LLC | 6,989 | $353.6K | 0.01% | −1,099−13.6% | Reduced |
| Castle Rock Wealth Management, LLC | 6,972 | $351.5K | 0.11% | 00.0% | Unchanged |
| Sherbrooke Park Advisers LLC | 6,789 | $343.5K | 0.16% | +1,851+37.5% | Added |
| Baird Financial Group, Inc. | 6,689 | $338.4K | 0.00% | −85−1.3% | Reduced |
| Lazard Asset Management LLC | 6,641 | $335.0K | 0.00% | +84+1.3% | Added |
| Virtus ETF Advisers LLC | 6,548 | $331.3K | 0.21% | −909−12.2% | Reduced |
| Sectoral Asset Management Inc | 6,480 | $327.8K | 0.14% | +6,480 | New |
| Aquatic Capital Management LLC | 6,400 | $324.0K | 0.01% | +6,400 | New |
| SG Americas Securities, LLC | 6,129 | $310.0K | 0.00% | −35,442−85.3% | Reduced |
| Weiss Asset Management LP | 5,874 | $297.2K | 0.02% | +5,874 | New |
| Kapitalo Investimentos Ltda | 5,714 | $289.1K | 0.06% | +5,714 | New |
| Ci Investments Inc. | 5,588 | $283.0K | 0.00% | +3,064+121.4% | Added |
| Massachusetts Financial Services Co | 5,592 | $282.9K | 0.00% | −177−3.1% | Reduced |
| Perkins Capital Management Inc | 5,550 | $281.0K | 0.24% | 00.0% | Unchanged |
| Legato Capital Management LLC | 5,455 | $276.0K | 0.04% | +5,455 | New |
| Capital Wealth Planning, LLC | 5,408 | $273.6K | 0.00% | +5,408 | New |
| Dynamic Technology Lab Private Ltd | 5,273 | $267.0K | 0.03% | +5,273 | New |
| M&T Bank Corp | 5,188 | $263.0K | 0.00% | +376+7.8% | Added |
| Buckingham Strategic Wealth, LLC | 5,170 | $261.6K | 0.00% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 5,040 | $255.0K | 0.00% | +62+1.2% | Added |
| Oracle Alpha Inc. | 5,019 | $253.9K | 0.33% | +5,019 | New |
| Beaird Harris Wealth Management, LLC | 5,000 | $252.9K | 0.03% | 00.0% | Unchanged |
| Vident Advisory, LLC | 4,930 | $249.4K | 0.01% | −656−11.7% | Reduced |
| Prospera Financial Services Inc | 4,698 | $237.7K | 0.01% | −55−1.2% | Reduced |
| Mercer Global Advisors Inc | 4,676 | $237.0K | 0.00% | −420−8.2% | Reduced |
| Mitchell & Pahl Private Wealth, LLC | 4,617 | $233.6K | 0.13% | −5−0.1% | Reduced |
| Koss-Olinger Consulting, LLC | 4,539 | $230.0K | 0.02% | −13,368−74.7% | Reduced |
| MML Investors Services, LLC | 4,324 | $219.0K | 0.00% | +4,324 | New |
| Level Four Advisory Services, LLC | 4,302 | $217.6K | 0.01% | +4,302 | New |
| Prudential Financial Inc | 4,269 | $216.0K | 0.00% | +4,269 | New |
| AQR Capital Management LLC | 4,300 | $214.3K | 0.00% | +4,300 | New |
| Checchi Capital Advisers, LLC | 4,234 | $214.2K | 0.02% | +4,234 | New |
| Berkshire Asset Management LLC | 4,180 | $211.5K | 0.01% | +4,180 | New |
| Regions Financial Corp | 4,085 | $206.7K | 0.00% | +4,085 | New |
| Cetera Advisor Networks LLC | 4,081 | $206.5K | 0.00% | −357−8.0% | Reduced |
| CIBC Asset Management Inc | 4,002 | $202.5K | 0.00% | +4,002 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 3,693 | $190.5K | 0.00% | −1,502−28.9% | Reduced |
| Tower Research Capital LLC (TRC) | 3,360 | $170.0K | 0.00% | +2,464+275.0% | Added |
| Natixis | 2,878 | $145.6K | 0.00% | +2,878 | New |
| KBC Group NV | 2,669 | $135.0K | 0.00% | 00.0% | Unchanged |
| Icon Wealth Advisors, LLC | 2,537 | $128.3K | 0.01% | +2,537 | New |
| Torno Capital, LLC | 2,500 | $126.5K | 0.13% | +2,500 | New |
| American International Group, Inc. | 2,237 | $113.2K | 0.00% | −61−2.7% | Reduced |
| CWM, LLC | 2,197 | $111.0K | 0.00% | −9−0.4% | Reduced |
| GWM Advisors LLC | 2,088 | $105.6K | 0.00% | +974+87.4% | Added |
| Horizon Investments, LLC | 1,927 | $97.5K | 0.00% | +28+1.5% | Added |
| Twin Lakes Capital Management, LLC | 1,500 | $75.9K | 0.05% | 00.0% | Unchanged |
| Itau Unibanco Holding S.A. | 1,429 | $72.3K | 0.00% | −378−20.9% | Reduced |
| IFP Advisors, Inc | 1,070 | $54.1K | 0.00% | −71−6.2% | Reduced |
| Group One Trading, L.P. | 1,018 | $51.5K | 0.00% | +700+220.1% | Added |
| Harbour Investments, Inc. | 900 | $45.5K | 0.00% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 878 | $44.4K | 0.04% | +878 | New |
| Archer Investment Corp | 850 | $43.0K | 0.01% | 00.0% | Unchanged |
| nVerses Capital, LLC | – | $40.5K | 0.11% | – | New |
| Allworth Financial LP | 776 | $39.3K | 0.00% | −125−13.9% | Reduced |
| Institutional & Family Asset Management, LLC | 729 | $36.9K | 0.01% | 00.0% | Unchanged |
| Global X Japan Co., Ltd. | 716 | $36.2K | 0.02% | +716 | New |
| Glassman Wealth Services | 686 | $34.7K | 0.00% | −53−7.2% | Reduced |
| Tennessee Valley Asset Management Partners | 673 | $34.0K | 0.01% | +673 | New |
| Quadrant Capital Group LLC | 671 | $33.9K | 0.00% | +83+14.1% | Added |
| Laurel Wealth Advisors LLC | 600 | $30.4K | 0.01% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 587 | $30.0K | 0.00% | +72+14.0% | Added |
| Farther Finance Advisors, LLC | 569 | $28.8K | 0.00% | +329+137.1% | Added |
| Parallel Advisors, LLC | 565 | $28.6K | 0.00% | −106−15.8% | Reduced |
| Allspring Global Investments Holdings, LLC | 555 | $28.1K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 519 | $26.3K | 0.00% | +519 | New |
| GAMMA Investing LLC | 500 | $25.7K | 0.01% | +500 | New |
| Signaturefd, LLC | 501 | $25.3K | 0.00% | +135+36.9% | Added |
| Pingora Partners LLC | 500 | $25.3K | 0.02% | +500 | New |
| Clearstead Advisors, LLC | 495 | $25.0K | 0.00% | +310+167.6% | Added |
| AlphaMark Advisors, LLC | 500 | $25.0K | 0.01% | 00.0% | Unchanged |