Skip to main content

Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
365
No complete 13F data for Q4 2020
Shares held
123.5M
No complete 13F data for Q4 2020
Total value
$5.55B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 365 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2021: $5.55B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc.

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding IONS in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund57,500$2.58M0.02%––
Great West Life Assurance Co57,476$2.57M0.01%––
DnB Asset Management AS56,658$2.55M0.02%––
LPL Financial LLC55,283$2.49M0.00%––
Susquehanna Fundamental Investments, LLC54,804$2.46M0.04%––
Sabby Management, LLC54,688$2.46M1.81%––
Skandinaviska Enskilda Banken AB (publ)54,493$2.45M0.02%––
Connor, Clark & Lunn Investment Management Ltd.51,579$2.32M0.01%––
Nisa Investment Advisors, LLC49,825$2.24M0.01%––
Pictet Asset Management Ltd49,000$2.20M0.00%––
Treasurer of the State of North Carolina47,917$2.15M0.01%––
Shell Asset Management Co46,133$2.07M0.04%––
SG Americas Securities, LLC45,808$2.06M0.01%––
Principal Financial Group Inc44,411$2.00M0.00%––
Creative Planning44,179$1.99M0.00%––
Capital Counsel LLC42,080$1.89M0.11%––
NJ State Employees Deferred Compensation Plan42,000$1.89M0.27%––
Arizona State Retirement System38,299$1.72M0.02%––
Gateway Investment Advisers LLC37,600$1.69M0.02%––
Storebrand Asset Management AS37,353$1.68M0.01%––
Janney Montgomery Scott LLC36,812$1.66M0.01%––
Canada Pension Plan Investment Board36,762$1.65M0.00%––
Raymond James Financial Services Advisors, Inc.35,529$1.60M0.00%––
Allianz Asset Management GmbH34,844$1.57M0.00%––
Erste Asset Management GmbH34,500$1.54M0.04%––
Seeyond33,701$1.51M0.15%––
Jane Street Group, LLC32,863$1.48M0.00%––
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.32,510$1.46M0.01%––
Employees Retirement System of Texas32,409$1.46M0.02%––
AMP Capital Investors Ltd31,333$1.41M0.01%––
Russell Investments Group, Ltd.30,931$1.39M0.00%––
Voya Investment Management LLC30,711$1.38M0.00%––
SEI Investments Co27,462$1.38M0.00%––
Macquarie Group Ltd30,457$1.37M0.00%––
First Foundation Advisors30,063$1.35M0.06%––
Korea Investment CORP29,900$1.34M0.00%––
Engineers Gate Manager LP29,160$1.31M0.06%––
UBS Group AG29,062$1.31M0.00%––
Group One Trading, L.P.28,911$1.30M0.03%––
BNP Paribas Arbitrage, SA28,640$1.29M0.00%––
Teacher Retirement System of Texas27,956$1.26M0.01%––
Vestmark Advisory Solutions, Inc.26,509$1.19M0.11%––
Eaton Vance Management26,470$1.19M0.00%––
Victory Capital Management Inc26,250$1.18M0.00%––
Stephens Inc25,156$1.13M0.02%––
Utah Retirement Systems25,109$1.13M0.02%––
Profund Advisors LLC24,797$1.11M0.04%––
Gulf International Bank (UK) Ltd23,940$1.08M0.01%––
Nomura Asset Management Co Ltd23,300$1.05M0.01%––
Handelsbanken Fonder AB23,011$1.03M0.01%––
Kestra Advisory Services, LLC22,950$1.03M0.01%––
Twinbeech Capital LP22,750$1.02M0.15%––
Gyon Technologies Capital Management, LP22,376$1.01M0.44%––
ProShare Advisors LLC22,135$995.0K0.00%––
British Columbia Investment Management Corp21,768$979.0K0.01%––
Truist Financial Corp21,664$974.0K0.00%––
Zurcher Kantonalbank (Zurich Cantonalbank)21,221$954.0K0.01%––
Schonfeld Strategic Advisors LLC21,101$948.0K0.01%––
Tanaka Capital Management Inc20,611$927.0K1.18%––
Natixis Advisors, L.P.20,604$926.0K0.00%––
Grandfield & Dodd, LLC20,353$920.0K0.07%––
AtonRa Partners20,146$906.0K0.40%––
Jefferies Group LLC20,127$904.9K0.02%––
SG3 Management, LLC20,000$899.0K0.29%––
MML Investors Services, LLC19,896$895.0K0.01%––
Amalgamated Bank19,666$884.0K0.03%––
Public Employees Retirement Association of Colorado19,604$881.0K0.00%––
Squarepoint Ops LLC19,587$881.0K0.01%––
Commonwealth Equity Services, LLC18,136$815.0K0.00%––
Private Advisor Group, LLC18,042$811.0K0.01%––
Toronto Dominion Bank17,977$808.0K0.00%––
Alexandria Capital, LLC17,762$799.0K0.08%––
Emerald Advisers, LLC17,621$792.0K0.03%––
Arden Trust Co16,506$742.0K0.12%––
Advisor Group Holdings, Inc.15,966$720.0K0.00%––
IFM Investors Pty Ltd15,830$712.0K0.02%––
Lincoln National Corp15,465$695.0K0.02%––
Optimal Asset Management, Inc.15,118$680.0K0.09%––
Comerica Bank15,696$670.0K0.00%––
Cambridge Investment Research Advisors, Inc.14,877$669.0K0.00%––
Castle Rock Wealth Management, LLC15,593$662.0K0.27%––
Ameriprise Financial Inc14,478$652.0K0.00%––
HSBC Holdings PLC14,415$648.0K0.00%––
Virtu Financial LLC14,360$646.0K0.05%––
Nissay Asset Management Corp14,204$639.0K0.01%––
NN Investment Partners Holdings N.V.14,118$635.0K0.00%––
North Star Asset Management Inc13,753$618.0K0.04%––
National Asset Management, Inc.12,998$616.0K0.02%––
US Bancorp13,586$610.0K0.00%––
Migdal Insurance & Financial Holdings Ltd.13,305$598.0K0.01%––
Virtus ETF Advisers LLC13,084$588.0K0.25%––
Ritholtz Wealth Management12,501$562.0K0.05%––
Voya Financial Advisors, Inc.12,433$556.0K0.02%––
Berkshire Asset Management LLC12,348$555.0K0.04%––
Tower Research Capital LLC (TRC)12,323$554.0K0.01%––
Reynders McVeigh Capital Management, LLC12,174$547.0K0.04%––
Panagora Asset Management Inc12,145$546.0K0.00%––
Bokf, NA11,710$526.0K0.01%––
KBC Group NV11,511$518.0K0.00%––
Blair William & Co11,164$502.0K0.00%––