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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2021

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
338
−24 vs. Q1 2021
Shares held
124.4M
+2.62M (+2.2%) vs. Q1 2021
Total value
$4.96B
−$516.2M (−9.4%) vs. Q1 2021
New holders
51
116 more added
Sold out
75
103 more reduced

3 institutions that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 338 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2021: $4.96B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2021.

Institutions holding IONS in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Huntington National Bank1$00.00%−62−98.4%Reduced
First Horizon Corp6$00.00%00.0%Unchanged
Gemmer Asset Management LLC3$00.00%00.0%Unchanged
Aspire Private Capital, LLC8$00.00%00.0%Unchanged
Kelly Financial Services LLC1,197$300.00%+567+90.0%Added
Lindbrook Capital, LLC16$1.00K0.00%−30−65.2%Reduced
Meeder Asset Management Inc14$1.00K0.00%00.0%Unchanged
AdvisorNet Financial, Inc29$1.00K0.00%00.0%Unchanged
Allworth Financial LP17$1.00K0.00%00.0%Unchanged
Cranbrook Wealth Management, LLC25$1.00K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC33$1.00K0.00%00.0%Unchanged
Private Capital Group, LLC31$1.00K0.00%00.0%Unchanged
Enterprise Financial Services Corp23$1.00K0.00%+12+109.1%Added
Covington Capital Management36$1.00K0.00%+36New
Parkside Financial Bank & Trust23$1.00K0.00%+23New
Stonebridge Capital Advisors LLC29$1.00K0.00%+29New
Sound Income Strategies, LLC20$1.00K0.00%+20New
Raffa Wealth Management, LLC28$1.12K0.00%00.0%Unchanged
Mitsubishi UFJ Trust & Banking Corp50$2.00K0.00%−79,901−99.9%Reduced
Benjamin F. Edwards & Company, Inc.56$2.00K0.00%−2,033−97.3%Reduced
Quadrant Capital Group LLC58$2.00K0.00%−207−78.1%Reduced
Prestige Wealth Management Group LLC60$2.00K0.00%−42−41.2%Reduced
Trustcore Financial Services, LLC58$2.00K0.00%00.0%Unchanged
Rockbridge Investment Management, LCC58$2.00K0.00%00.0%Unchanged
Earnest Partners LLC49$2.00K0.00%00.0%Unchanged
Harbor Investment Advisory, LLC38$2.00K0.00%00.0%Unchanged
Sargent Bickham Lagudis LLC43$2.00K0.00%00.0%Unchanged
Bedel Financial Consulting, Inc.38$2.00K0.00%00.0%Unchanged
Versant Capital Management, Inc46$2.00K0.00%00.0%Unchanged
Liberty Wealth Management LLC44$2.00K0.00%00.0%Unchanged
Orion Capital Management LLC38$2.00K0.00%00.0%Unchanged
Loring Wolcott & Coolidge Fiduciary Advisors LLP45$2.00K0.00%+45New
Clean Yield Group50$2.00K0.00%+50New
Global Wealth Management Investment Advisory, Inc.80$3.00K0.00%00.0%Unchanged
Eagle Bay Advisors LLC75$3.00K0.00%+75New
Whittier Trust Co100$4.00K0.00%00.0%Unchanged
Gradient Investments LLC91$4.00K0.00%00.0%Unchanged
Blume Capital Management, Inc.90$4.00K0.00%00.0%Unchanged
McCarthy Asset Management, Inc.110$4.00K0.00%+110New
Glassman Wealth Services121$5.00K0.00%−27−18.2%Reduced
Bogart Wealth, LLC125$5.00K0.00%00.0%Unchanged
Proequities, Inc.127$5.00K0.00%+5+4.1%Added
GPS Wealth Strategies Group, LLC119$5.00K0.00%00.0%Unchanged
TD Private Client Wealth LLC129$5.15K0.00%+99+330.0%Added
Pacifica Partners Inc.150$6.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.144$6.00K0.00%+109+311.4%Added
IAG Wealth Partners, LLC135$6.00K0.00%+135New
Logan Capital Management Inc178$7.00K0.00%00.0%Unchanged
Brown Brothers Harriman & Co200$8.00K0.00%−2,150−91.5%Reduced
AllSquare Wealth Management LLC198$8.00K0.00%00.0%Unchanged
AlphaMark Advisors, LLC200$8.00K0.00%+200New
Cordasco Financial Network200$8.00K0.01%+200New
Reilly Financial Advisors, LLC220$9.00K0.00%00.0%Unchanged
Pinnacle Bancorp, Inc.227$9.00K0.00%00.0%Unchanged
Firestone Capital Management250$10.0K0.00%00.0%Unchanged
Daiwa Securities Group Inc.279$11.0K0.00%−5,497−95.2%Reduced
O'Shaughnessy Asset Management, LLC285$11.0K0.00%+20+7.5%Added
Gables Capital Management Inc.275$11.0K0.01%00.0%Unchanged
FourThought Financial, LLC277$11.0K0.00%00.0%Unchanged
Berman Capital Advisors, LLC303$11.0K0.00%+110+57.0%Added
Zions Bancorporation, N.A.266$11.0K0.00%+203+322.2%Added
American Portfolios Advisors300$12.0K0.00%00.0%Unchanged
Spire Wealth Management295$12.0K0.00%−2,209−88.2%Reduced
SkyView Investment Advisors, LLC271$12.0K0.01%00.0%Unchanged
Heritage Wealth Advisors334$13.3K0.00%00.0%Unchanged
Banque Cantonale Vaudoise400$16.0K0.00%−2,400−85.7%Reduced
Global Trust Asset Management, LLC399$16.0K0.01%00.0%Unchanged
Parallel Advisors, LLC428$17.0K0.00%−2,534−85.6%Reduced
Hall Laurie J Trustee430$17.0K0.01%−550−56.1%Reduced
Concord Wealth Partners417$17.0K0.00%00.0%Unchanged
Heritage Wealth Management, LLC450$18.0K0.01%00.0%Unchanged
Ellis Investment Partners, LLC500$19.0K0.00%00.0%Unchanged
Advisory Services Network, LLC519$21.0K0.00%+519New
NuWave Investment Management, LLC551$22.0K0.02%+551New
Laurel Wealth Advisors LLC600$24.0K0.01%00.0%Unchanged
CWM, LLC690$28.0K0.00%00.0%Unchanged
Patriot Financial Group Insurance Agency, LLC718$29.0K0.01%+189+35.7%Added
S.A. Mason LLC775$31.0K0.02%00.0%Unchanged
Institutional & Family Asset Management, LLC765$31.0K0.01%00.0%Unchanged
Wolverine Asset Management LLC783$31.0K0.00%+783New
Cutler Group LP800$31.0K0.00%+800New
Carroll Financial Associates, Inc.883$35.0K0.00%00.0%Unchanged
Itau Unibanco Holding S.A.868$35.0K0.00%+868New
Bessemer Group Inc900$36.0K0.00%−129−12.5%Reduced
Signaturefd, LLC973$39.0K0.00%+194+24.9%Added
Riggs Asset Managment Co. Inc.1,000$40.0K0.01%00.0%Unchanged
Wolff Wiese Magana LLC1,131$45.0K0.03%00.0%Unchanged
IFP Advisors, Inc1,179$45.0K0.00%+881+295.6%Added
First Manhattan Co1,200$47.0K0.00%−374,100−99.7%Reduced
NEXT Financial Group, Inc1,247$50.0K0.00%−1,570−55.7%Reduced
Kistler-Tiffany Companies, LLC1,281$51.0K0.01%−300−19.0%Reduced
Dark Forest Capital Management LP1,310$52.0K0.02%+1,310New
Healthcare of Ontario Pension Plan Trust Fund1,484$59.0K0.00%+1,484New
Twin Lakes Capital Management, LLC1,500$60.0K0.03%00.0%Unchanged
Northwestern Mutual Wealth Management Co1,528$61.0K0.00%−411−21.2%Reduced
Harbour Investments, Inc.1,695$68.0K0.00%−10−0.6%Reduced
Lazard Asset Management LLC1,891$74.0K0.00%+1,854+5,010.8%Added
Captrust Financial Advisors1,896$76.0K0.00%−77−3.9%Reduced
Walled Lake Planning & Wealth Management, LLC1,900$76.0K0.05%00.0%Unchanged
Panagora Asset Management Inc2,329$93.0K0.00%−9,816−80.8%Reduced