Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Amundi | 140,776 | $5.75M | 0.00% | −131,874−48.4% | Reduced |
| California State Teachers Retirement System | 131,818 | $5.71M | 0.01% | −6,714−4.8% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 130,986 | $5.68M | 0.13% | −38,692−22.8% | Reduced |
| Avidity Partners Management LP | 130,000 | $5.64M | 0.20% | +130,000 | New |
| Envestnet Asset Management Inc | 129,972 | $5.63M | 0.00% | −3,512−2.6% | Reduced |
| State Board of Administration of Florida Retirement System | 155,145 | $5.54M | 0.01% | +4,090+2.7% | Added |
| Superstring Capital Management LP | 120,896 | $5.24M | 3.47% | −68,722−36.2% | Reduced |
| Peregrine Capital Management LLC | 118,598 | $5.14M | 0.15% | +10,774+10.0% | Added |
| Jane Street Group, LLC | 118,132 | $5.12M | 0.01% | −36,032−23.4% | Reduced |
| Granite Investment Partners, LLC | 116,144 | $5.03M | 0.19% | −3,802−3.2% | Reduced |
| Schroder Investment Management Group | 115,658 | $5.01M | 0.01% | +72,658+169.0% | Added |
| Raymond James & Associates | 112,554 | $4.88M | 0.00% | −71,122−38.7% | Reduced |
| Dimensional Fund Advisors LP | 109,303 | $4.74M | 0.00% | −15,914−12.7% | Reduced |
| DekaBank Deutsche Girozentrale | 93,807 | $4.16M | 0.01% | +2,193+2.4% | Added |
| Campbell & CO Investment Adviser LLC | 94,772 | $4.11M | 0.35% | +94,772 | New |
| State of Wisconsin Investment Board | 91,815 | $3.98M | 0.01% | −11,750−11.3% | Reduced |
| Van Eck Associates Corp | 91,101 | $3.95M | 0.01% | +25,270+38.4% | Added |
| Walleye Capital LLC | 89,130 | $3.86M | 0.04% | +89,130 | New |
| Trexquant Investment LP | 85,352 | $3.70M | 0.07% | −27,635−24.5% | Reduced |
| Davenport & Co LLC | 83,928 | $3.64M | 0.02% | −2,400−2.8% | Reduced |
| Commerce Bank | 82,433 | $3.57M | 0.02% | +15,416+23.0% | Added |
| State of New Jersey Common Pension Fund D | 81,847 | $3.55M | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 79,887 | $3.46M | 0.01% | +9,714+13.8% | Added |
| LPL Financial LLC | 79,722 | $3.46M | 0.00% | −7,577−8.7% | Reduced |
| Citadel Advisors LLC | 78,030 | $3.38M | 0.00% | −174,498−69.1% | Reduced |
| Nicola Wealth Management Ltd. | 56,000 | $3.29M | 0.32% | 00.0% | Unchanged |
| Parkwood LLC | 71,259 | $3.09M | 0.33% | −37,295−34.4% | Reduced |
| HRT Financial LP | 66,503 | $2.88M | 0.02% | +66,503 | New |
| HealthInvest Partners AB | 63,791 | $2.77M | 1.68% | +39,548+163.1% | Added |
| Treasurer of the State of North Carolina | 63,582 | $2.76M | 0.01% | +430+0.7% | Added |
| Janus Henderson Group PLC | 59,717 | $2.59M | 0.00% | +140.0% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.58M | 0.01% | 00.0% | Unchanged |
| Public Employees Retirement System of Ohio | 54,493 | $2.36M | 0.01% | −5,137−8.6% | Reduced |
| Voya Investment Management LLC | 54,196 | $2.35M | 0.00% | −22,715−29.5% | Reduced |
| Ensign Peak Advisors, Inc | 53,320 | $2.31M | 0.00% | +7,010+15.1% | Added |
| Erste Asset Management GmbH | 51,300 | $2.29M | 0.03% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 47,976 | $2.08M | 0.01% | −831−1.7% | Reduced |
| Twinbeech Capital LP | 46,364 | $2.01M | 0.04% | +16,635+56.0% | Added |
| Susquehanna Fundamental Investments, LLC | 45,574 | $1.98M | 0.09% | +45,574 | New |
| UBS Oconnor LLC | 42,412 | $1.84M | 0.05% | +13,788+48.2% | Added |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.82M | 0.23% | 00.0% | Unchanged |
| Great West Life Assurance Co | 41,880 | $1.82M | 0.00% | +1,099+2.7% | Added |
| Capital Counsel LLC | 39,580 | $1.72M | 0.08% | −500−1.2% | Reduced |
| Comerica Bank | 39,491 | $1.71M | 0.01% | −123−0.3% | Reduced |
| Engineers Gate Manager LP | 38,592 | $1.67M | 0.04% | +9,715+33.6% | Added |
| Nicholas Investment Partners, LP | 38,186 | $1.66M | 0.17% | +7,741+25.4% | Added |
| NEOS Investment Management LLC | 37,303 | $1.62M | 0.10% | +28,397+318.9% | Added |
| Guggenheim Capital LLC | 35,850 | $1.55M | 0.01% | +2,699+8.1% | Added |
| Arizona State Retirement System | 35,487 | $1.54M | 0.01% | −572−1.6% | Reduced |
| Handelsbanken Fonder AB | 33,911 | $1.47M | 0.01% | +6,900+25.5% | Added |
| Grandfield & Dodd, LLC | 33,774 | $1.46M | 0.09% | +670+2.0% | Added |
| Profund Advisors LLC | 31,570 | $1.37M | 0.05% | +2,497+8.6% | Added |
| Graham Capital Management, L.P. | 30,541 | $1.32M | 0.04% | +18,016+143.8% | Added |
| Lighthouse Investment Partners, LLC | 30,379 | $1.32M | 0.08% | +30,379 | New |
| Algert Global LLC | 30,242 | $1.31M | 0.05% | +12,830+73.7% | Added |
| STRS Ohio | 29,965 | $1.30M | 0.01% | +5,186+20.9% | Added |
| Teza Capital Management LLC | 29,936 | $1.30M | 0.17% | +20,203+207.6% | Added |
| Principal Financial Group Inc | 29,824 | $1.29M | 0.00% | −1,315−4.2% | Reduced |
| Teacher Retirement System of Texas | 28,736 | $1.25M | 0.01% | −1,108−3.7% | Reduced |
| Point72 (DIFC) Ltd | 28,491 | $1.24M | 0.10% | +28,491 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 28,144 | $1.22M | 0.00% | −1,296−4.4% | Reduced |
| China Universal Asset Management Co., Ltd. | 28,027 | $1.21M | 0.15% | +11,429+68.9% | Added |
| Blair William & Co | 27,838 | $1.21M | 0.00% | +11,210+67.4% | Added |
| Lisanti Capital Growth, LLC | 27,835 | $1.21M | 0.29% | −34,580−55.4% | Reduced |
| Creative Planning | 27,005 | $1.17M | 0.00% | +1,706+6.7% | Added |
| Janney Montgomery Scott LLC | 26,893 | $1.17M | 0.00% | −1,486−5.2% | Reduced |
| Pearl River Capital, LLC | 25,959 | $1.13M | 0.18% | +25,959 | New |
| Teachers Retirement System of the State of Kentucky | 24,083 | $1.04M | 0.01% | +9,965+70.6% | Added |
| Natixis Advisors, L.P. | 23,028 | $998.0K | 0.00% | +5,715+33.0% | Added |
| Commonwealth Equity Services, LLC | 21,974 | $953.0K | 0.00% | +512+2.4% | Added |
| Cetera Investment Advisers | 21,758 | $943.2K | 0.00% | +21,758 | New |
| Pathstone Holdings, LLC | 21,253 | $921.3K | 0.00% | +9,371+78.9% | Added |
| Mariner, LLC | 20,784 | $901.0K | 0.00% | +112+0.5% | Added |
| Nicollet Investment Management, Inc. | 20,521 | $890.0K | 0.33% | +10,745+109.9% | Added |
| Toroso Investments, LLC | 20,405 | $884.6K | 0.02% | +20,405 | New |
| Edgestream Partners, L.P. | 17,646 | $765.0K | 0.04% | +17,646 | New |
| Victory Capital Management Inc | 17,637 | $764.6K | 0.00% | −10,156−36.5% | Reduced |
| NBT Bank N A | 17,050 | $739.1K | 0.05% | 00.0% | Unchanged |
| Aigen Investment Management, LP | 16,747 | $726.0K | 0.16% | −56,973−77.3% | Reduced |
| Public Employees Retirement Association of Colorado | 16,574 | $718.0K | 0.00% | 00.0% | Unchanged |
| Bleakley Financial Group, LLC | 16,229 | $703.5K | 0.02% | +3,990+32.6% | Added |
| Simplicity Wealth,LLC | 16,229 | $703.5K | 0.02% | +16,229 | New |
| Xponance, Inc. | 16,209 | $702.7K | 0.01% | −484−2.9% | Reduced |
| Jump Financial, LLC | 15,693 | $680.3K | 0.02% | −46,046−74.6% | Reduced |
| Ameriprise Financial Inc | 15,673 | $679.4K | 0.00% | −9,952−38.8% | Reduced |
| Marshall Wace, LLP | 15,443 | $669.5K | 0.00% | −118,106−88.4% | Reduced |
| Advisor Group Holdings, Inc. | 14,626 | $633.9K | 0.00% | −4,284−22.7% | Reduced |
| Tanaka Capital Management Inc | 14,612 | $633.0K | 1.56% | 00.0% | Unchanged |
| Entropy Technologies, LP | 14,542 | $630.4K | 0.07% | +14,542 | New |
| Neuberger Berman Group LLC | 14,234 | $617.0K | 0.00% | +236+1.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 15,081 | $613.4K | 0.00% | +15,081 | New |
| Westmount Partners, LLC | 13,872 | $601.4K | 0.22% | 00.0% | Unchanged |
| North Star Asset Management Inc | 13,640 | $591.3K | 0.03% | −10−0.1% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 13,508 | $585.6K | 0.00% | −139−1.0% | Reduced |
| American Century Companies Inc | 13,378 | $579.9K | 0.00% | +162+1.2% | Added |
| Martingale Asset Management L P | 13,315 | $577.2K | 0.01% | +30.0% | Added |
| Bank Julius Baer & Co. Ltd, Zurich | 14,230 | $570.6K | 0.00% | −4,820−25.3% | Reduced |
| Horizon Kinetics Asset Management LLC | 12,476 | $540.8K | 0.01% | 00.0% | Unchanged |
| Wolverine Trading, LLC | 12,047 | $522.2K | 0.01% | +2,552+26.9% | Added |
| US Bancorp | 11,927 | $517.0K | 0.00% | −8−0.1% | Reduced |