Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 361
- −2 vs. Q4 2023
- Shares held
- 142.2M
- −349.1K (−0.2%) vs. Q4 2023
- Total value
- $6.17B
- −$1.04B (−14.4%) vs. Q4 2023
- New holders
- 49
- 124 more added
- Sold out
- 51
- 127 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Chartwell Investment Partners, LLC | 11,756 | $510.0K | 0.02% | −1,226−9.4% | Reduced |
| Aquatic Capital Management LLC | 11,700 | $507.2K | 0.02% | +5,300+82.8% | Added |
| Plancorp, LLC | 11,155 | $483.6K | 0.02% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 11,146 | $483.2K | 0.00% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 11,122 | $482.1K | 0.02% | −4,282−27.8% | Reduced |
| Brown Advisory Inc | 11,122 | $482.1K | 0.00% | −422−3.7% | Reduced |
| PEAK6 Investments LLC | 11,000 | $476.9K | 0.02% | +1,999+22.2% | Added |
| Suvretta Capital Management, LLC | 10,800 | $468.2K | 0.02% | +10,800 | New |
| Corton Capital Inc. | 10,631 | $460.9K | 0.17% | −845−7.4% | Reduced |
| Maryland State Retirement & Pension System | 10,950 | $451.5K | 0.01% | 00.0% | Unchanged |
| Capula Management Ltd | 10,217 | $442.9K | 0.01% | +10,217 | New |
| ProShare Advisors LLC | 10,216 | $442.9K | 0.00% | +1,049+11.4% | Added |
| Sherbrooke Park Advisers LLC | 10,119 | $438.7K | 0.09% | +3,330+49.0% | Added |
| Sectoral Asset Management Inc | 10,100 | $437.8K | 0.17% | +3,620+55.9% | Added |
| Cypress Capital, LLC | 10,000 | $433.5K | 0.12% | +10,000 | New |
| Bard Financial Services, Inc. | 9,950 | $431.3K | 0.05% | −4,150−29.4% | Reduced |
| Oppenheimer Asset Management Inc. | 9,826 | $426.0K | 0.01% | −723−6.9% | Reduced |
| E Fund Management Co., Ltd. | 9,825 | $425.9K | 0.03% | −40−0.4% | Reduced |
| Franklin Resources Inc | 9,809 | $425.2K | 0.00% | −3,896−28.4% | Reduced |
| Midwest Professional Planners, LTD. | 9,716 | $421.2K | 0.15% | +1,197+14.1% | Added |
| Fifth Third Bancorp | 9,633 | $417.6K | 0.00% | +351+3.8% | Added |
| Truist Financial Corp | 9,499 | $411.8K | 0.00% | −466−4.7% | Reduced |
| Walleye Trading LLC | 9,362 | $405.8K | 0.01% | +9,214+6,225.7% | Added |
| Cambridge Investment Research Advisors, Inc. | 9,312 | $404.0K | 0.00% | −1,722−15.6% | Reduced |
| Amalgamated Bank | 9,203 | $399.0K | 0.00% | −19,792−68.3% | Reduced |
| The PNC Financial Services Group, Inc. | 8,819 | $382.3K | 0.00% | +441+5.3% | Added |
| Deutsche Bank AG | 8,588 | $372.3K | 0.00% | −27,114−75.9% | Reduced |
| XTX Topco Ltd | 8,585 | $372.2K | 0.05% | +8,585 | New |
| Simplex Trading, LLC | 8,530 | $369.0K | 0.01% | −1,015−10.6% | Reduced |
| Centiva Capital, LP | 8,474 | $367.3K | 0.02% | +8,474 | New |
| Gsa Capital Partners LLP | 8,325 | $361.0K | 0.03% | −3,355−28.7% | Reduced |
| Torno Capital, LLC | 8,000 | $346.8K | 0.07% | +5,500+220.0% | Added |
| Utah Retirement Systems | 7,900 | $342.5K | 0.00% | 00.0% | Unchanged |
| Stephens Inc | 7,853 | $340.4K | 0.01% | −102−1.3% | Reduced |
| MetLife Investment Management | 7,841 | $339.9K | 0.00% | +24+0.3% | Added |
| Lazard Asset Management LLC | 7,855 | $339.0K | 0.00% | +1,214+18.3% | Added |
| International Assets Investment Management, LLC | 7,607 | $334.3K | 0.03% | +7,607 | New |
| Virtus ETF Advisers LLC | 7,648 | $331.5K | 0.18% | +1,100+16.8% | Added |
| SG Americas Securities, LLC | 7,582 | $329.0K | 0.00% | +1,453+23.7% | Added |
| Twin Tree Management, LP | 7,563 | $327.9K | 0.01% | +7,563 | New |
| Vontobel Holding Ltd. | 7,497 | $325.0K | 0.00% | −713−8.7% | Reduced |
| JustInvest LLC | 7,363 | $319.2K | 0.01% | −979−11.7% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 6,986 | $302.8K | 0.08% | +6,986 | New |
| Castle Rock Wealth Management, LLC | 6,972 | $299.9K | 0.08% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 6,786 | $294.2K | 0.00% | −203−2.9% | Reduced |
| Regions Financial Corp | 6,785 | $294.1K | 0.00% | +2,700+66.1% | Added |
| Baird Financial Group, Inc. | 6,696 | $290.3K | 0.00% | +7+0.1% | Added |
| Wrapmanager Inc | 6,668 | $289.1K | 0.08% | −736−9.9% | Reduced |
| Diversified Trust Co | 6,015 | $260.8K | 0.01% | +6,015 | New |
| Acadian Asset Management LLC | 5,891 | $255.0K | 0.00% | +5,891 | New |
| M&T Bank Corp | 5,848 | $253.7K | 0.00% | +660+12.7% | Added |
| Massachusetts Financial Services Co | 5,580 | $241.9K | 0.00% | −12−0.2% | Reduced |
| Perkins Capital Management Inc | 5,550 | $241.0K | 0.20% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 5,550 | $240.6K | 0.00% | +510+10.1% | Added |
| Handelsinvest Investeringsforvaltning | 5,287 | $229.0K | 0.11% | −2,746−34.2% | Reduced |
| Buckingham Strategic Wealth, LLC | 5,251 | $227.6K | 0.00% | +81+1.6% | Added |
| Level Four Advisory Services, LLC | 4,396 | $222.4K | 0.01% | +94+2.2% | Added |
| HighTower Advisors, LLC | 5,085 | $221.0K | 0.00% | −6,001−54.1% | Reduced |
| Beaird Harris Wealth Management, LLC | 5,000 | $216.8K | 0.02% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 4,924 | $213.5K | 0.02% | +4,924 | New |
| Paloma Partners Management Co | 4,909 | $212.8K | 0.03% | +4,909 | New |
| Tower Research Capital LLC (TRC) | 4,863 | $210.8K | 0.01% | +1,503+44.7% | Added |
| Vident Advisory, LLC | 4,796 | $207.9K | 0.00% | −134−2.7% | Reduced |
| Prospera Financial Services Inc | 4,617 | $200.1K | 0.01% | −81−1.7% | Reduced |
| Quantbot Technologies LP | 4,284 | $185.7K | 0.01% | −8,419−66.3% | Reduced |
| Ci Investments Inc. | 3,967 | $172.0K | 0.00% | −1,621−29.0% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 3,842 | $166.6K | 0.00% | +149+4.0% | Added |
| Advisors Asset Management, Inc. | 3,178 | $137.8K | 0.00% | +2,875+948.8% | Added |
| KBC Group NV | 3,145 | $136.0K | 0.00% | +476+17.8% | Added |
| ADAR1 Capital Management, LLC | 2,900 | $125.7K | 0.03% | +2,900 | New |
| Icon Wealth Advisors, LLC | 2,391 | $103.7K | 0.01% | −146−5.8% | Reduced |
| Horizon Investments, LLC | 2,347 | $101.7K | 0.00% | +420+21.8% | Added |
| Quest Partners LLC | 2,297 | $99.6K | 0.02% | +2,296+229,600.0% | Added |
| CWM, LLC | 2,228 | $97.0K | 0.00% | +31+1.4% | Added |
| American International Group, Inc. | 2,208 | $95.7K | 0.00% | −29−1.3% | Reduced |
| CIBC Private Wealth Group, LLC | 2,168 | $95.3K | 0.00% | +2,168 | New |
| GWM Advisors LLC | 2,025 | $87.8K | 0.00% | −63−3.0% | Reduced |
| Natixis | 1,961 | $85.0K | 0.00% | −917−31.9% | Reduced |
| Twin Lakes Capital Management, LLC | 1,500 | $65.0K | 0.04% | 00.0% | Unchanged |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 1,104 | $47.9K | 0.00% | +1,104 | New |
| IFP Advisors, Inc | 1,070 | $46.4K | 0.00% | 00.0% | Unchanged |
| Sunbelt Securities, Inc. | 1,014 | $44.0K | 0.00% | +1,014 | New |
| Pacer Advisors, Inc. | 971 | $42.1K | 0.00% | +971 | New |
| Harbour Investments, Inc. | 900 | $39.0K | 0.00% | 00.0% | Unchanged |
| Archer Investment Corp | 850 | $36.8K | 0.01% | 00.0% | Unchanged |
| Allworth Financial LP | 796 | $34.5K | 0.00% | +20+2.6% | Added |
| Mather Group, LLC. | 671 | $33.9K | 0.00% | +671 | New |
| Steward Partners Investment Advisory, LLC | 723 | $31.3K | 0.00% | +242+50.3% | Added |
| Institutional & Family Asset Management, LLC | 691 | $30.0K | 0.00% | −38−5.2% | Reduced |
| Global X Japan Co., Ltd. | 669 | $29.0K | 0.01% | −47−6.6% | Reduced |
| GAMMA Investing LLC | 612 | $26.5K | 0.01% | +112+22.4% | Added |
| Laurel Wealth Advisors LLC | 600 | $26.0K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 569 | $25.0K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 574 | $24.9K | 0.00% | −97−14.5% | Reduced |
| Parallel Advisors, LLC | 572 | $24.8K | 0.00% | +7+1.2% | Added |
| Daiwa Securities Group Inc. | 541 | $23.0K | 0.00% | −46−7.8% | Reduced |
| Pingora Partners LLC | 500 | $21.7K | 0.02% | 00.0% | Unchanged |
| Riverview Trust Co | 476 | $20.6K | 0.02% | +476 | New |
| Global Trust Asset Management, LLC | 474 | $20.5K | 0.01% | 00.0% | Unchanged |
| Elequin Capital LP | 474 | $20.5K | 0.00% | +474 | New |