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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
361
−2 vs. Q4 2023
Shares held
142.2M
−349.1K (−0.2%) vs. Q4 2023
Total value
$6.17B
−$1.04B (−14.4%) vs. Q4 2023
New holders
49
124 more added
Sold out
51
127 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 361 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ1 2024: $6.17B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2023.

Institutions holding IONS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Clearstead Advisors, LLC495$19.2K0.00%00.0%Unchanged
AlphaMark Advisors, LLC400$17.0K0.01%−100−20.0%Reduced
Banque Cantonale Vaudoise400$17.0K0.00%00.0%Unchanged
Private Trust Co NA378$16.4K0.00%+11+3.0%Added
Huntington National Bank363$15.7K0.00%+74+25.6%Added
Signaturefd, LLC355$15.4K0.00%−146−29.1%Reduced
Whittier Trust Co of Nevada Inc341$14.8K0.00%00.0%Unchanged
Lindbrook Capital, LLC314$13.6K0.00%−79−20.1%Reduced
Riggs Asset Managment Co. Inc.282$12.2K0.00%+32+12.8%Added
Storebrand Asset Management AS271$11.7K0.00%00.0%Unchanged
Washington Trust Advisors, Inc.258$11.2K0.00%00.0%Unchanged
Covestor Ltd242$11.0K0.01%−1−0.4%Reduced
Whittier Trust Co231$10.0K0.00%−231−50.0%Reduced
EverSource Wealth Advisors, LLC237$9.78K0.00%−103−30.3%Reduced
Leonteq Securities AG212$9.19K0.00%+212New
SYSTM Wealth Solutions LLC204$8.84K0.00%00.0%Unchanged
LifeSteps Financial, Inc.200$8.67K0.01%+200New
Catalyst Funds Management Pty Ltd200$8.67K0.00%+200New
AllSquare Wealth Management LLC198$8.58K0.01%00.0%Unchanged
GPS Wealth Strategies Group, LLC184$7.98K0.00%−14−7.1%Reduced
Pacifica Partners Inc.150$6.58K0.00%00.0%Unchanged
Sachetta, LLC115$5.82K0.00%00.0%Unchanged
Spire Wealth Management125$5.42K0.00%00.0%Unchanged
Creekmur Asset Management LLC100$4.33K0.00%00.0%Unchanged
Global Retirement Partners, LLC94$4.08K0.00%+3+3.3%Added
Bogart Wealth, LLC85$3.69K0.00%00.0%Unchanged
Exchange Traded Concepts, LLC82$3.56K0.00%+82New
Orion Capital Management LLC80$3.47K0.00%+42+110.5%Added
EntryPoint Capital, LLC76$3.29K0.00%−802−91.3%Reduced
National Bank of Canada80$3.13K0.00%+80New
Raleigh Capital Management Inc.72$3.12K0.00%00.0%Unchanged
Bell Investment Advisors, Inc71$3.08K0.00%00.0%Unchanged
Semmax Financial Advisors Inc.79$3.07K0.00%−3−3.7%Reduced
Dynamic Wealth Strategies, LLC80$3.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB67$2.90K0.00%00.0%Unchanged
Parkside Financial Bank & Trust62$2.69K0.00%00.0%Unchanged
Versant Capital Management, Inc59$2.56K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.38K0.00%00.0%Unchanged
Quent Capital, LLC55$2.38K0.00%+34+161.9%Added
Bessemer Group Inc52$2.00K0.00%00.0%Unchanged
Cornerstone Planning Group LLC45$1.89K0.00%−64−58.7%Reduced
Sandy Spring Bank34$1.47K0.00%+34New
CVA Family Office, LLC30$1.30K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.30K0.00%00.0%Unchanged
First Pacific Financial29$1.26K0.00%+9+45.0%Added
Raffa Wealth Management, LLC28$1.21K0.00%00.0%Unchanged
Smartleaf Asset Management LLC26$1.16K0.00%+26New
CoreCap Advisors, LLC26$1.13K0.00%+26New
SRS Capital Advisors, Inc.25$1.08K0.00%−59−70.2%Reduced
Rosenberg Matthew Hamilton20$8790.00%00.0%Unchanged
Front Row Advisors LLC20$8670.00%00.0%Unchanged
Key Financial Inc19$8240.00%00.0%Unchanged
Proequities, Inc.19$8230.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC16$6930.00%−539−97.1%Reduced
Retirement Group, LLC11$4770.00%00.0%Unchanged
Private Wealth Management Group, LLC10$4340.00%00.0%Unchanged
Bokf, NA7$3080.00%+7New
Manchester Capital Management LLC5$2170.00%00.0%Unchanged
Abich Financial Wealth Management LLC4$1730.00%+4New
Assetmark, Inc1$430.00%−6−85.7%Reduced
Capital Advisors, Ltd. LLC7$00.00%+7New
Camber Capital Management LP0$00.00%−865,000−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−127,954−100.0%Sold out
Cinctive Capital Management LP0$00.00%−73,256−100.0%Sold out
HighVista Strategies LLC0$00.00%−57,348−100.0%Sold out
Cowen and Company, LLC0$00.00%−51,415−100.0%Sold out
Estate Counselors, LLC0$00.00%−32,800−100.0%Sold out
Fred Alger Management, LLC0$00.00%−24,054−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−20,015−100.0%Sold out
Calamos Advisors LLC0$00.00%−16,379−100.0%Sold out
Friedenthal Financial0$00.00%−14,225−100.0%Sold out
Granite Bay Wealth Management, LLC0$00.00%−13,579−100.0%Sold out
Captrust Financial Advisors0$00.00%−10,108−100.0%Sold out
Point72 Middle East FZE0$00.00%−9,983−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−9,271−100.0%Sold out
Weiss Asset Management LP0$00.00%−5,874−100.0%Sold out
Kapitalo Investimentos Ltda0$00.00%−5,714−100.0%Sold out
Legato Capital Management LLC0$00.00%−5,455−100.0%Sold out
Capital Wealth Planning, LLC0$00.00%−5,408−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−5,273−100.0%Sold out
Oracle Alpha Inc.0$00.00%−5,019−100.0%Sold out
Mercer Global Advisors Inc0$00.00%−4,676−100.0%Sold out
Mitchell & Pahl Private Wealth, LLC0$00.00%−4,617−100.0%Sold out
Koss-Olinger Consulting, LLC0$00.00%−4,539−100.0%Sold out
MML Investors Services, LLC0$00.00%−4,324−100.0%Sold out
Prudential Financial Inc0$00.00%−4,269−100.0%Sold out
AQR Capital Management LLC0$00.00%−4,300−100.0%Sold out
Checchi Capital Advisers, LLC0$00.00%−4,234−100.0%Sold out
Berkshire Asset Management LLC0$00.00%−4,180−100.0%Sold out
Cetera Advisor Networks LLC0$00.00%−4,081−100.0%Sold out
CIBC Asset Management Inc0$00.00%−4,002−100.0%Sold out
Itau Unibanco Holding S.A.0$00.00%−1,429−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,018−100.0%Sold out
nVerses Capital, LLC0$00.00%–Sold out
Glassman Wealth Services0$00.00%−686−100.0%Sold out
Tennessee Valley Asset Management Partners0$00.00%−673−100.0%Sold out
Advisory Services Network, LLC0$00.00%−519−100.0%Sold out
ORG Partners LLC0$00.00%−400−100.0%Sold out
Quarry LP0$00.00%−200−100.0%Sold out
Colonial Trust Co0$00.00%−120−100.0%Sold out