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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
357
−1 vs. Q1 2024
Shares held
143.3M
+1.29M (+0.9%) vs. Q1 2024
Total value
$6.83B
+$666.0M (+10.8%) vs. Q1 2024
New holders
52
120 more added
Sold out
53
132 more reduced

3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 357 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2024: $6.83B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2024.

Institutions holding IONS in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Huntington National Bank322$15.3K0.00%−41−11.3%Reduced
Storebrand Asset Management AS271$12.9K0.00%00.0%Unchanged
Global X Japan Co., Ltd.262$12.5K0.00%−407−60.8%Reduced
Covestor Ltd243$12.0K0.01%+1+0.4%Added
Riggs Asset Managment Co. Inc.250$11.9K0.00%−32−11.3%Reduced
EverSource Wealth Advisors, LLC238$11.8K0.00%+1+0.4%Added
Whittier Trust Co of Nevada Inc218$10.4K0.00%−123−36.1%Reduced
Whittier Trust Co214$10.2K0.00%−17−7.4%Reduced
Parkside Financial Bank & Trust199$9.48K0.00%+137+221.0%Added
AllSquare Wealth Management LLC198$9.44K0.01%00.0%Unchanged
LRI Investments, LLC187$8.91K0.00%+187New
Allspring Global Investments Holdings, LLC166$7.91K0.00%+150+937.5%Added
Natixis163$7.77K0.00%−1,798−91.7%Reduced
Ashton Thomas Private Wealth, LLC150$7.15K0.00%+150New
Pacifica Partners Inc.150$6.84K0.00%00.0%Unchanged
Dunhill Financial, LLC130$6.20K0.00%+130New
Unique Wealth Strategies, LLC140$6.07K0.00%+140New
Spire Wealth Management125$5.96K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC119$5.67K0.00%−65−35.3%Reduced
Washington Trust Advisors, Inc.111$5.29K0.00%−147−57.0%Reduced
SRS Capital Advisors, Inc.104$4.96K0.00%+79+316.0%Added
Sachetta, LLC98$4.88K0.00%−17−14.8%Reduced
Creekmur Asset Management LLC100$4.77K0.00%00.0%Unchanged
Global Retirement Partners, LLC98$4.67K0.00%+4+4.3%Added
Ronald Blue Trust, Inc.107$4.64K0.00%+107New
Family Firm, Inc.91$4.34K0.00%+91New
Bogart Wealth, LLC85$4.05K0.00%00.0%Unchanged
Dynamic Wealth Strategies, LLC80$4.00K0.00%00.0%Unchanged
Private Trust Co NA83$3.96K0.00%−295−78.0%Reduced
Orion Capital Management LLC80$3.81K0.00%00.0%Unchanged
National Bank of Canada80$3.75K0.00%00.0%Unchanged
Semmax Financial Advisors Inc.79$3.71K0.00%00.0%Unchanged
Quent Capital, LLC74$3.53K0.00%+19+34.5%Added
SYSTM Wealth Solutions LLC73$3.48K0.00%−131−64.2%Reduced
Raleigh Capital Management Inc.72$3.43K0.00%00.0%Unchanged
Bell Investment Advisors, Inc71$3.38K0.00%00.0%Unchanged
Smartleaf Asset Management LLC59$2.79K0.00%+33+126.9%Added
Massmutual Trust Co FSB58$2.76K0.00%−9−13.4%Reduced
Blume Capital Management, Inc.55$2.62K0.00%00.0%Unchanged
Versant Capital Management, Inc55$2.62K0.00%−4−6.8%Reduced
Innealta Capital, LLC47$2.24K0.00%+47New
Healthcare of Ontario Pension Plan Trust Fund46$2.19K0.00%+46New
Abich Financial Wealth Management LLC45$2.15K0.00%+41+1,025.0%Added
Great Lakes Retirement, Inc.43$2.05K0.00%+43New
Bessemer Group Inc52$2.00K0.00%00.0%Unchanged
Sandy Spring Bank34$1.62K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.43K0.00%00.0%Unchanged
Raffa Wealth Management, LLC28$1.33K0.00%00.0%Unchanged
Proequities, Inc.26$1.24K0.00%+7+36.8%Added
TFC Financial Management21$1.00K0.00%+21New
Front Row Advisors LLC20$9530.00%00.0%Unchanged
Thurston, Springer, Miller, Herd & Titak, Inc.20$9530.00%+20New
Rosenberg Matthew Hamilton20$9420.00%00.0%Unchanged
Key Financial Inc19$9060.00%00.0%Unchanged
Larson Financial Group LLC18$8580.00%+18New
Principal Securities, Inc.13$6200.00%+13New
Private Wealth Management Group, LLC10$4770.00%00.0%Unchanged
First Turn Management, LLC0$00.00%−421,487−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−191,367−100.0%Sold out
Senator Investment Group LP0$00.00%−135,000−100.0%Sold out
Superstring Capital Management LP0$00.00%−120,896−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−94,772−100.0%Sold out
Parkwood LLC0$00.00%−71,259−100.0%Sold out
Twinbeech Capital LP0$00.00%−46,364−100.0%Sold out
Nicholas Investment Partners, LP0$00.00%−38,186−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−30,541−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−30,379−100.0%Sold out
STRS Ohio0$00.00%−29,965−100.0%Sold out
Cetera Investment Advisers0$00.00%−21,758−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−17,646−100.0%Sold out
Aigen Investment Management, LP0$00.00%−16,747−100.0%Sold out
Entropy Technologies, LP0$00.00%−14,542−100.0%Sold out
Bank Julius Baer & Co. Ltd, Zurich0$00.00%−14,230−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−11,700−100.0%Sold out
Corton Capital Inc.0$00.00%−10,631−100.0%Sold out
Capula Management Ltd0$00.00%−10,217−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−10,119−100.0%Sold out
Bard Financial Services, Inc.0$00.00%−9,950−100.0%Sold out
Walleye Trading LLC0$00.00%−9,362−100.0%Sold out
XTX Topco Ltd0$00.00%−8,585−100.0%Sold out
Centiva Capital, LP0$00.00%−8,474−100.0%Sold out
Torno Capital, LLC0$00.00%−8,000−100.0%Sold out
SG Americas Securities, LLC0$00.00%−7,582−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−6,986−100.0%Sold out
Regions Financial Corp0$00.00%−6,785−100.0%Sold out
Baird Financial Group, Inc.0$00.00%−6,696−100.0%Sold out
Wrapmanager Inc0$00.00%−6,668−100.0%Sold out
Diversified Trust Co0$00.00%−6,015−100.0%Sold out
Acadian Asset Management LLC0$00.00%−5,891−100.0%Sold out
Massachusetts Financial Services Co0$00.00%−5,580−100.0%Sold out
Level Four Advisory Services, LLC0$00.00%−4,396−100.0%Sold out
Paloma Partners Management Co0$00.00%−4,909−100.0%Sold out
Vident Advisory, LLC0$00.00%−4,796−100.0%Sold out
Quantbot Technologies LP0$00.00%−4,284−100.0%Sold out
Icon Wealth Advisors, LLC0$00.00%−2,391−100.0%Sold out
American International Group, Inc.0$00.00%−2,208−100.0%Sold out
Nelson, Van Denburg & Campbell Wealth Management Group, LLC0$00.00%−1,104−100.0%Sold out
Elequin Capital LP0$00.00%−474−100.0%Sold out
Leonteq Securities AG0$00.00%−212−100.0%Sold out
LifeSteps Financial, Inc.0$00.00%−200−100.0%Sold out