Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 354
- +1 vs. Q2 2024
- Shares held
- 157.5M
- +24.6M (+18.5%) vs. Q2 2024
- Total value
- $6.31B
- −$23.0M (−0.4%) vs. Q2 2024
- New holders
- 53
- 131 more added
- Sold out
- 52
- 107 more reduced
4 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Russell Investments Group, Ltd. | 128,469 | $5.15M | 0.01% | −4,267−3.2% | Reduced |
| Squarepoint Ops LLC | 127,341 | $5.10M | 0.02% | −309,477−70.8% | Reduced |
| California State Teachers Retirement System | 126,180 | $5.05M | 0.01% | −3,036−2.3% | Reduced |
| Walleye Capital LLC | 124,116 | $4.97M | 0.05% | +26,245+26.8% | Added |
| Amundi | 128,299 | $4.85M | 0.00% | −1,176−0.9% | Reduced |
| Nicola Wealth Management Ltd. | 87,000 | $4.71M | 0.37% | +13,000+17.6% | Added |
| Eisler Capital (US) LLC | 117,565 | $4.71M | 0.87% | +101,295+622.6% | Added |
| Cutter Capital Management, LP | 97,300 | $3.90M | 1.15% | −62,866−39.3% | Reduced |
| Voya Investment Management LLC | 95,821 | $3.84M | 0.00% | +702+0.7% | Added |
| DekaBank Deutsche Girozentrale | 93,807 | $3.80M | 0.01% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 94,332 | $3.78M | 0.00% | +5,586+6.3% | Added |
| Prudential Financial Inc | 90,017 | $3.61M | 0.01% | +74,300+472.7% | Added |
| State of Wisconsin Investment Board | 86,166 | $3.45M | 0.01% | −1,534−1.7% | Reduced |
| Granite Investment Partners, LLC | 85,793 | $3.44M | 0.15% | −28,297−24.8% | Reduced |
| HealthInvest Partners AB | 82,691 | $3.31M | 1.56% | +42,000+103.2% | Added |
| Engineers Gate Manager LP | 78,874 | $3.16M | 0.06% | +62,554+383.3% | Added |
| Commerce Bank | 77,553 | $3.11M | 0.02% | +1,211+1.6% | Added |
| Davenport & Co LLC | 75,598 | $3.03M | 0.02% | −5,080−6.3% | Reduced |
| Deutsche Bank AG | 74,874 | $3.00M | 0.00% | +65,778+723.2% | Added |
| Liontrust Investment Partners LLP | 59,644 | $2.84M | 0.04% | 00.0% | Unchanged |
| Citigroup Inc | 70,295 | $2.82M | 0.00% | −6,323−8.3% | Reduced |
| Ensign Peak Advisors, Inc | 69,880 | $2.80M | 0.00% | +1,610+2.4% | Added |
| Treasurer of the State of North Carolina | 68,363 | $2.74M | 0.01% | +5,250+8.3% | Added |
| Neuberger Berman Group LLC | 64,874 | $2.60M | 0.00% | +50,562+353.3% | Added |
| Sphera Funds Management Ltd. | 63,821 | $2.56M | 0.42% | −76,417−54.5% | Reduced |
| HBK Investments L P | 60,000 | $2.40M | 0.04% | +60,000 | New |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $2.39M | 0.01% | 00.0% | Unchanged |
| NEOS Investment Management LLC | 59,244 | $2.37M | 0.07% | +14,186+31.5% | Added |
| Janus Henderson Group PLC | 58,977 | $2.36M | 0.00% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 58,814 | $2.36M | 0.00% | −18,601−24.0% | Reduced |
| Schroder Investment Management Group | 56,222 | $2.30M | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 57,239 | $2.29M | 0.00% | −38,619−40.3% | Reduced |
| Public Employees Retirement System of Ohio | 56,825 | $2.28M | 0.01% | +1,529+2.8% | Added |
| Teacher Retirement System of Texas | 56,699 | $2.27M | 0.01% | +4,147+7.9% | Added |
| Van Eck Associates Corp | 59,006 | $2.27M | 0.00% | +8,742+17.4% | Added |
| Tudor Investment Corp Et Al | 53,479 | $2.14M | 0.02% | +40,381+308.3% | Added |
| Jefferies Financial Group Inc. | 52,781 | $2.11M | 0.03% | −9,419−15.1% | Reduced |
| Erste Asset Management GmbH | 51,300 | $2.10M | 0.03% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 52,162 | $2.09M | 0.00% | +894+1.7% | Added |
| State of New Jersey Common Pension Fund D | 51,775 | $2.07M | 0.01% | −3,574−6.5% | Reduced |
| Blair William & Co | 46,651 | $1.87M | 0.01% | +21,389+84.7% | Added |
| Algert Global LLC | 45,430 | $1.82M | 0.05% | −29,920−39.7% | Reduced |
| Private Advisor Group, LLC | 43,787 | $1.75M | 0.01% | −2,639−5.7% | Reduced |
| Handelsbanken Fonder AB | 43,011 | $1.72M | 0.01% | +9,100+26.8% | Added |
| LPL Financial LLC | 42,620 | $1.71M | 0.00% | −8,794−17.1% | Reduced |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.68M | 0.20% | 00.0% | Unchanged |
| Great West Life Assurance Co | 39,835 | $1.60M | 0.00% | −5,713−12.5% | Reduced |
| Baillie Gifford & Co | 39,581 | $1.59M | 0.00% | −220,673−84.8% | Reduced |
| DCF Advisers, LLC | 39,500 | $1.58M | 0.81% | +16,500+71.7% | Added |
| Arizona State Retirement System | 37,827 | $1.52M | 0.01% | +1,105+3.0% | Added |
| Profund Advisors LLC | 37,596 | $1.51M | 0.06% | +7,613+25.4% | Added |
| Guggenheim Capital LLC | 37,159 | $1.49M | 0.01% | +1,770+5.0% | Added |
| Capital Counsel LLC | 37,080 | $1.49M | 0.06% | 00.0% | Unchanged |
| UBS Oconnor LLC | 36,957 | $1.48M | 0.04% | −5,638−13.2% | Reduced |
| Polar Asset Management Partners Inc. | 35,400 | $1.42M | 0.03% | +35,400 | New |
| Grandfield & Dodd, LLC | 34,813 | $1.39M | 0.08% | +760+2.2% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 30,922 | $1.24M | 0.00% | −233−0.7% | Reduced |
| Capital Fund Management S.A. | 30,691 | $1.23M | 0.01% | +30,691 | New |
| Artia Global Partners LP | 30,479 | $1.22M | 0.35% | −32,000−51.2% | Reduced |
| Brevan Howard Capital Management LP | 28,479 | $1.14M | 0.05% | +6,632+30.4% | Added |
| Creative Planning | 28,382 | $1.14M | 0.00% | +1,522+5.7% | Added |
| China Universal Asset Management Co., Ltd. | 28,121 | $1.13M | 0.12% | +10,971+64.0% | Added |
| Pathstone Holdings, LLC | 27,807 | $1.11M | 0.00% | +5,102+22.5% | Added |
| Caption Management, LLC | 26,600 | $1.07M | 0.11% | −133,400−83.4% | Reduced |
| Landscape Capital Management, L.L.C. | 25,435 | $1.02M | 0.10% | +25,435 | New |
| Teachers Retirement System of the State of Kentucky | 24,083 | $965.0K | 0.01% | 00.0% | Unchanged |
| Castle Hook Partners LP | 23,940 | $959.0K | 0.03% | +23,940 | New |
| Mariner, LLC | 23,127 | $927.6K | 0.00% | +1,273+5.8% | Added |
| Lazard Asset Management LLC | 22,923 | $917.0K | 0.00% | +13,408+140.9% | Added |
| Raymond James & Associates | 22,524 | $902.3K | 0.00% | −1,049−4.5% | Reduced |
| Commonwealth Equity Services, LLC | 21,453 | $859.0K | 0.00% | −1,216−5.4% | Reduced |
| Natixis Advisors, L.P. | 21,080 | $844.0K | 0.00% | −2,324−9.9% | Reduced |
| Nicollet Investment Management, Inc. | 20,402 | $817.0K | 0.28% | +294+1.5% | Added |
| Y-Intercept (Hong Kong) Ltd | 20,141 | $806.8K | 0.05% | +20,141 | New |
| Monashee Investment Management LLC | 20,000 | $801.2K | 0.09% | +20,000 | New |
| Xponance, Inc. | 19,021 | $762.0K | 0.01% | +906+5.0% | Added |
| Toroso Investments, LLC | 18,908 | $757.5K | 0.01% | −42−0.2% | Reduced |
| Victory Capital Management Inc | 18,350 | $735.1K | 0.00% | +1,020+5.9% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 17,741 | $710.7K | 0.00% | −26,515−59.9% | Reduced |
| Seven Eight Capital, LP | 17,394 | $696.8K | 0.06% | +17,394 | New |
| Capula Management Ltd | 17,365 | $695.6K | 0.01% | +17,365 | New |
| NBT Bank N A | 17,050 | $683.0K | 0.05% | 00.0% | Unchanged |
| XTX Topco Ltd | 16,805 | $673.2K | 0.05% | +16,805 | New |
| Bleakley Financial Group, LLC | 16,678 | $668.1K | 0.02% | +338+2.1% | Added |
| Advisor Group Holdings, Inc. | 16,372 | $655.7K | 0.00% | +1,680+11.4% | Added |
| Public Employees Retirement Association of Colorado | 15,589 | $624.0K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Services Advisors, Inc. | 14,570 | $583.7K | 0.00% | −765−5.0% | Reduced |
| Tanaka Capital Management Inc | 14,512 | $581.0K | 1.34% | 00.0% | Unchanged |
| Chartwell Investment Partners, LLC | 13,759 | $551.0K | 0.02% | 00.0% | Unchanged |
| North Star Asset Management Inc | 13,640 | $546.4K | 0.02% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 13,500 | $540.8K | 0.03% | −1,501−10.0% | Reduced |
| Westmount Partners, LLC | 13,462 | $539.3K | 0.16% | 00.0% | Unchanged |
| PDT Partners, LLC | 13,400 | $536.8K | 0.05% | −30−0.2% | Reduced |
| Assenagon Asset Management S.A. | 13,298 | $532.7K | 0.00% | −10,928−45.1% | Reduced |
| Principal Financial Group Inc | 13,112 | $525.3K | 0.00% | −4,346−24.9% | Reduced |
| Martingale Asset Management L P | 12,809 | $513.1K | 0.01% | +40.0% | Added |
| Stratos Wealth Partners, LTD. | 12,788 | $512.3K | 0.01% | −30.0% | Reduced |
| E Fund Management Co., Ltd. | 12,752 | $510.8K | 0.03% | +2,497+24.3% | Added |
| Brown Advisory Inc | 12,746 | $510.6K | 0.00% | +1,780+16.2% | Added |
| Twin Tree Management, LP | 12,428 | $497.9K | 0.01% | +2,047+19.7% | Added |