Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 350
- −1 vs. Q2 2022
- Shares held
- 126.4M
- +1.80M (+1.4%) vs. Q2 2022
- Total value
- $5.59B
- +$976.9M (+21.2%) vs. Q2 2022
- New holders
- 50
- 97 more added
- Sold out
- 51
- 130 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alps Advisors Inc | 77,480 | $3.43M | 0.03% | −6,635−7.9% | Reduced |
| Public Employees Retirement System of Ohio | 76,123 | $3.37M | 0.02% | +780+1.0% | Added |
| PFS Investments Inc. | 75,202 | $3.33M | 0.07% | +1,077+1.5% | Added |
| LPL Financial LLC | 74,740 | $3.31M | 0.00% | −7,347−9.0% | Reduced |
| Liontrust Investment Partners LLP | 72,269 | $3.20M | 0.05% | −122,223−62.8% | Reduced |
| Eaton Vance Management | 70,682 | $3.13M | 0.00% | +1,084+1.6% | Added |
| Cubist Systematic Strategies, LLC | 70,408 | $3.11M | 0.02% | −78,980−52.9% | Reduced |
| Voya Investment Management LLC | 70,275 | $3.11M | 0.00% | +13,720+24.3% | Added |
| Deutsche Bank AG | 65,426 | $2.89M | 0.00% | +32,961+101.5% | Added |
| UBS Group AG | 61,310 | $2.71M | 0.00% | −108,857−64.0% | Reduced |
| Algert Global LLC | 60,937 | $2.69M | 0.16% | +36,037+144.7% | Added |
| Treasurer of the State of North Carolina | 60,522 | $2.68M | 0.02% | +780+1.3% | Added |
| Principal Financial Group Inc | 60,269 | $2.67M | 0.00% | −51,899−46.3% | Reduced |
| Alliancebernstein L.P. | 58,102 | $2.57M | 0.00% | −2,758−4.5% | Reduced |
| Intech Investment Management LLC | 57,140 | $2.53M | 0.02% | +57,140 | New |
| Trexquant Investment LP | 55,564 | $2.46M | 0.09% | +27,141+95.5% | Added |
| Guggenheim Capital LLC | 54,969 | $2.43M | 0.02% | −8,777−13.8% | Reduced |
| UBS Oconnor LLC | 54,497 | $2.41M | 0.03% | −7,000−11.4% | Reduced |
| Graham Capital Management, L.P. | 53,717 | $2.38M | 0.10% | −7,296−12.0% | Reduced |
| National Bank of Canada | 51,720 | $2.29M | 0.01% | +51,720 | New |
| Erste Asset Management GmbH | 51,300 | $2.27M | 0.05% | 00.0% | Unchanged |
| Gateway Investment Advisers LLC | 50,199 | $2.22M | 0.03% | −48,930−49.4% | Reduced |
| Rhenman & Partners Asset Management AB | 50,000 | $2.21M | 0.23% | 00.0% | Unchanged |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.86M | 0.32% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 41,844 | $1.85M | 0.01% | +21,579+106.5% | Added |
| Susquehanna International Group, LLP | 40,870 | $1.81M | 0.00% | +3,317+8.8% | Added |
| Capital Counsel LLC | 40,230 | $1.78M | 0.12% | −780−1.9% | Reduced |
| Brookstone Capital Management | 38,035 | $1.75M | 0.04% | +12,694+50.1% | Added |
| Envestnet Asset Management Inc | 39,264 | $1.74M | 0.00% | −1,101−2.7% | Reduced |
| Highland Capital Management, LLC | 38,873 | $1.72M | 0.13% | −286−0.7% | Reduced |
| Ameriprise Financial Inc | 38,703 | $1.71M | 0.00% | +27,319+240.0% | Added |
| Koss-Olinger Consulting, LLC | 35,939 | $1.59M | 0.27% | −2,983−7.7% | Reduced |
| Arizona State Retirement System | 34,680 | $1.53M | 0.02% | +239+0.7% | Added |
| Raymond James Financial Services Advisors, Inc. | 32,564 | $1.44M | 0.00% | −21,666−40.0% | Reduced |
| Janney Montgomery Scott LLC | 32,415 | $1.43M | 0.01% | +1,757+5.7% | Added |
| Ensign Peak Advisors, Inc | 32,315 | $1.43M | 0.00% | +7,445+29.9% | Added |
| Amalgamated Bank | 31,592 | $1.40M | 0.01% | −1,731−5.2% | Reduced |
| Toronto Dominion Bank | 31,306 | $1.38M | 0.00% | +31,306 | New |
| Grandfield & Dodd, LLC | 29,071 | $1.29M | 0.11% | +795+2.8% | Added |
| Allianz Asset Management GmbH | 28,880 | $1.28M | 0.00% | +6,383+28.4% | Added |
| EAM Investors, LLC | 28,396 | $1.26M | 0.27% | +28,396 | New |
| Virginia Retirement Systems Et Al | 26,600 | $1.18M | 0.01% | +26,600 | New |
| Federated Hermes, Inc. | 26,127 | $1.16M | 0.00% | −1,110−4.1% | Reduced |
| Aquatic Capital Management LLC | 25,500 | $1.13M | 0.11% | +25,500 | New |
| Vestmark Advisory Solutions, Inc. | 25,199 | $1.11M | 0.06% | +1,604+6.8% | Added |
| Twin Tree Management, LP | 23,517 | $1.04M | 0.03% | +23,517 | New |
| Gotham Asset Management, LLC | 23,240 | $1.03M | 0.03% | −38,244−62.2% | Reduced |
| Janus Henderson Group PLC | 23,140 | $1.02M | 0.00% | −67−0.3% | Reduced |
| Capital Fund Management S.A. | 23,023 | $1.02M | 0.03% | −16,087−41.1% | Reduced |
| Kestra Advisory Services, LLC | 22,925 | $1.01M | 0.01% | +94+0.4% | Added |
| Commonwealth Equity Services, LLC | 21,247 | $939.0K | 0.00% | −2,517−10.6% | Reduced |
| Tudor Investment Corp Et Al | 21,109 | $934.0K | 0.02% | −53,083−71.5% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $923.0K | 0.01% | 00.0% | Unchanged |
| Ziegler Capital Management, LLC | 20,659 | $914.0K | 0.04% | −120−0.6% | Reduced |
| Jane Street Group, LLC | 20,629 | $913.0K | 0.00% | −70,260−77.3% | Reduced |
| Castle Rock Wealth Management, LLC | 19,885 | $906.0K | 0.46% | +4,292+27.5% | Added |
| Acadian Asset Management LLC | 20,390 | $898.0K | 0.00% | +20,390 | New |
| Public Employees Retirement Association of Colorado | 19,604 | $867.0K | 0.00% | 00.0% | Unchanged |
| Knowledge Leaders Capital, LLC | 19,360 | $856.0K | 1.09% | −15,280−44.1% | Reduced |
| SEI Investments Co | 19,129 | $845.0K | 0.00% | +8,503+80.0% | Added |
| Millennium Management LLC | 18,929 | $837.0K | 0.00% | −301,686−94.1% | Reduced |
| Handelsbanken Fonder AB | 18,511 | $819.0K | 0.01% | 00.0% | Unchanged |
| AtonRa Partners | 17,628 | $780.0K | 0.77% | −518−2.9% | Reduced |
| STRS Ohio | 17,308 | $765.0K | 0.00% | +17,308 | New |
| Great West Life Assurance Co | 17,135 | $757.0K | 0.00% | +10,415+155.0% | Added |
| Calamos Advisors LLC | 17,119 | $757.0K | 0.00% | +17,119 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 16,734 | $740.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 16,198 | $717.0K | 0.00% | −1,125−6.5% | Reduced |
| Natixis Advisors, L.P. | 15,818 | $700.0K | 0.00% | −12−0.1% | Reduced |
| Victory Capital Management Inc | 15,795 | $699.0K | 0.00% | +2,249+16.6% | Added |
| Xponance, Inc. | 15,540 | $687.0K | 0.01% | +122+0.8% | Added |
| Profund Advisors LLC | 15,477 | $685.0K | 0.05% | −726−4.5% | Reduced |
| Blair William & Co | 14,844 | $657.0K | 0.00% | +237+1.6% | Added |
| AlphaCrest Capital Management LLC | 14,770 | $653.0K | 0.04% | −21,677−59.5% | Reduced |
| ProShare Advisors LLC | 14,198 | $628.0K | 0.00% | +831+6.2% | Added |
| Creative Planning | 13,892 | $614.0K | 0.00% | +1,163+9.1% | Added |
| North Star Asset Management Inc | 13,680 | $605.0K | 0.04% | 00.0% | Unchanged |
| Storebrand Asset Management AS | 13,062 | $577.7K | 0.00% | −9,400−41.8% | Reduced |
| Lincoln National Corp | 12,830 | $567.0K | 0.01% | −431−3.3% | Reduced |
| Strategic Wealth Advisors Group, LLC | 12,729 | $563.0K | 0.02% | +639+5.3% | Added |
| SG Americas Securities, LLC | 12,698 | $562.0K | 0.01% | −59,859−82.5% | Reduced |
| Arden Trust Co | 11,916 | $527.0K | 0.13% | −276−2.3% | Reduced |
| Tower Research Capital LLC (TRC) | 11,755 | $520.0K | 0.01% | +10,325+722.0% | Added |
| Qube Research & Technologies Ltd | 11,697 | $517.0K | 0.00% | +11,697 | New |
| Comerica Bank | 11,539 | $516.0K | 0.00% | −145−1.2% | Reduced |
| Advisor Group Holdings, Inc. | 11,535 | $510.0K | 0.00% | −5,889−33.8% | Reduced |
| Vontobel Holding Ltd. | 11,282 | $499.0K | 0.01% | −2,928−20.6% | Reduced |
| Shell Asset Management Co | 11,265 | $498.0K | 0.02% | −2,951−20.8% | Reduced |
| Plancorp, LLC | 11,255 | $498.0K | 0.03% | +20+0.2% | Added |
| Franklin Resources Inc | 11,251 | $497.0K | 0.00% | +11,251 | New |
| Neuberger Berman Group LLC | 11,199 | $495.0K | 0.00% | +113+1.0% | Added |
| Hanseatic Management Services Inc | 10,993 | $486.0K | 1.31% | −229−2.0% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 10,922 | $483.0K | 0.00% | −200−1.8% | Reduced |
| Oppenheimer Asset Management Inc. | 10,834 | $479.0K | 0.01% | −69−0.6% | Reduced |
| Occudo Quantitative Strategies LP | 10,766 | $476.0K | 0.04% | −50,905−82.5% | Reduced |
| Brown Advisory Inc | 10,630 | $470.0K | 0.00% | +1,000+10.4% | Added |
| Teza Capital Management LLC | 10,248 | $453.0K | 0.09% | −1,977−16.2% | Reduced |
| E Fund Management Co., Ltd. | 10,170 | $450.0K | 0.04% | −2,427−19.3% | Reduced |
| American Century Companies Inc | 10,079 | $446.0K | 0.00% | +2,724+37.0% | Added |
| Waddell & Associates, LLC | 10,042 | $444.0K | 0.09% | 00.0% | Unchanged |