Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2024 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2024/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 356
- 較 2024 年第 3 季 +9 家
- 持有股數
- 1.60 億
- 較 2024 年第 3 季 +310.4 萬 (+2.0%)
- 總市值
- $56.1 億
- 較 2024 年第 3 季 −$6.92 億 (−11.0%)
- 新進機構
- 58
- 另有 119 家加碼
- 清倉機構
- 49
- 另有 121 家減碼
另有 7 家機構在 2024 年第 3 季持有、還沒有申報 2024 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2024 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2024 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 22,689,491 | $7.93 億 | 0.05% | +209,962+0.9% | 加碼 |
| Vanguard Group Inc | 16,472,539 | $5.76 億 | 0.01% | +1,416,781+9.4% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 14,169,199 | $4.95 億 | 0.31% | +1,0830.0% | 加碼 |
| BlackRock, Inc. | 11,665,548 | $4.08 億 | 0.01% | +852,525+7.9% | 加碼 |
| Capital World Investors | 11,465,413 | $4.01 億 | 0.06% | +3,637,041+46.5% | 加碼 |
| Wellington Management Group LLP | 8,672,148 | $3.03 億 | 0.06% | −63,639−0.7% | 減碼 |
| Bellevue Group AG | 7,868,700 | $2.75 億 | 5.30% | −5,700−0.1% | 減碼 |
| State Street Corp | 5,426,413 | $1.90 億 | 0.01% | +576,276+11.9% | 加碼 |
| Price T Rowe Associates Inc | 3,826,939 | $1.34 億 | 0.02% | −383,233−9.1% | 減碼 |
| Tweedy, Browne Co LLC | 3,248,863 | $1.14 億 | 7.66% | −205,813−6.0% | 減碼 |
| OrbiMed Advisors LLC | 2,817,347 | $9,849 萬 | 2.05% | +492,900+21.2% | 加碼 |
| Geode Capital Management, LLC | 2,687,248 | $9,398 萬 | 0.01% | +18,890+0.7% | 加碼 |
| Citadel Advisors LLC | 2,165,916 | $7,572 萬 | 0.07% | +1,764,765+439.9% | 加碼 |
| Deep Track Capital, LP | 1,933,928 | $6,761 萬 | 2.53% | −266,072−12.1% | 減碼 |
| UBS Group AG | 1,917,608 | $6,704 萬 | 0.02% | +1,749,728+1,042.2% | 加碼 |
| Macquarie Group Ltd | 1,769,743 | $6,187 萬 | 0.08% | −100,063−5.4% | 減碼 |
| Norges Bank | 1,714,762 | $5,995 萬 | 0.01% | −312,399−15.4% | 減碼 |
| Clearbridge Investments, LLC | 1,618,220 | $5,657 萬 | 0.05% | −84,173−4.9% | 減碼 |
| Charles Schwab Investment Management Inc | 1,481,440 | $5,179 萬 | 0.01% | +38,420+2.7% | 加碼 |
| Two Sigma Advisers, LP | 1,349,211 | $4,717 萬 | 0.11% | +16,800+1.3% | 加碼 |
| Morgan Stanley | 1,329,929 | $4,649 萬 | 0.00% | +19,478+1.5% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,080,341 | $3,777 萬 | 0.09% | +300,620+38.6% | 加碼 |
| TD Asset Management Inc | 1,049,990 | $3,671 萬 | 0.03% | −43,000−3.9% | 減碼 |
| ARK Investment Management LLC大師方舟投資 | 1,025,260 | $3,584 萬 | 0.30% | −359,009−25.9% | 減碼 |
| Two Sigma Investments, LP | 921,439 | $3,221 萬 | 0.07% | +2,362+0.3% | 加碼 |
| Candriam Luxembourg S.C.A. | 849,824 | $2,971 萬 | 0.17% | −98,442−10.4% | 減碼 |
| Northern Trust Corp | 840,271 | $2,938 萬 | 0.00% | +97,367+13.1% | 加碼 |
| Hudson Bay Capital Management LP | 821,200 | $2,871 萬 | 0.17% | +54,300+7.1% | 加碼 |
| Marshall Wace, LLP | 812,306 | $2,840 萬 | 0.04% | −1,108,158−57.7% | 減碼 |
| Invesco Ltd. | 788,599 | $2,757 萬 | 0.01% | −21,702−2.7% | 減碼 |
| Millennium Management LLC | 774,215 | $2,707 萬 | 0.02% | +343,492+79.7% | 加碼 |
| Royal Bank of Canada | 643,192 | $2,249 萬 | 0.00% | −26,957−4.0% | 減碼 |
| Camber Capital Management LP | 625,000 | $2,185 萬 | 0.85% | +625,000 | 新進 |
| Pictet Asset Management Holding SA | 620,798 | $2,170 萬 | 0.02% | −682,703−52.4% | 減碼 |
| UBS Asset Management Americas Inc | 619,641 | $2,166 萬 | 0.01% | +333,944+116.9% | 加碼 |
| Bank of New York Mellon Corp | 616,071 | $2,154 萬 | 0.00% | +5,178+0.8% | 加碼 |
| J. Goldman & Co LP | 607,499 | $2,124 萬 | 0.75% | −1,917−0.3% | 減碼 |
| AXA S.A. | 605,345 | $2,116 萬 | 0.06% | +44,102+7.9% | 加碼 |
| Barclays PLC | 596,072 | $2,084 萬 | 0.01% | −40,960−6.4% | 減碼 |
| Vestal Point Capital, LP | 595,000 | $2,080 萬 | 1.23% | +595,000 | 新進 |
| Pinnacle Associates Ltd | 547,642 | $1,915 萬 | 0.26% | +88,663+19.3% | 加碼 |
| Groupama Asset Managment | 517,191 | $1,855 萬 | 0.38% | +101,131+24.3% | 加碼 |
| Great Point Partners LLC | 505,007 | $1,766 萬 | 8.32% | +250,007+98.0% | 加碼 |
| Bank of America Corp | 422,861 | $1,478 萬 | 0.00% | −145,799−25.6% | 減碼 |
| JPMorgan Chase & Co | 415,919 | $1,454 萬 | 0.00% | −152,987−26.9% | 減碼 |
| Standard Life Aberdeen plc | 401,501 | $1,403 萬 | 0.03% | +98,227+32.4% | 加碼 |
| C WorldWide Group Holding A/S | 400,000 | $1,398 萬 | 0.17% | +100,000+33.3% | 加碼 |
| Ameriprise Financial Inc | 387,448 | $1,354 萬 | 0.00% | −10,450−2.6% | 減碼 |
| Goldman Sachs Group Inc | 378,208 | $1,322 萬 | 0.00% | +142,498+60.5% | 加碼 |
| Schonfeld Strategic Advisors LLC | 371,381 | $1,298 萬 | 0.08% | +8,493+2.3% | 加碼 |
| Baker Bros. Advisors LP | 357,915 | $1,251 萬 | 0.13% | +134,445+60.2% | 加碼 |
| Nomura Holdings Inc | 357,255 | $1,249 萬 | 0.07% | −95,814−21.1% | 減碼 |
| Tocqueville Asset Management L.P. | 352,140 | $1,231 萬 | 0.19% | −54,730−13.5% | 減碼 |
| Wells Fargo & Company | 331,009 | $1,157 萬 | 0.00% | −11,145−3.3% | 減碼 |
| Voloridge Investment Management, LLC | 316,943 | $1,108 萬 | 0.04% | −63,698−16.7% | 減碼 |
| Bank of Montreal | 312,146 | $1,091 萬 | 0.01% | +98,263+45.9% | 加碼 |
| Nuveen Asset Management, LLC | 290,954 | $1,017 萬 | 0.00% | −13,825−4.5% | 減碼 |
| Manufacturers Life Insurance Company, The | 286,279 | $1,001 萬 | 0.01% | −22,668−7.3% | 減碼 |
| Jacobs Levy Equity Management, Inc | 281,813 | $985.2 萬 | 0.03% | −368,966−56.7% | 減碼 |
| Swiss National Bank | 279,200 | $976.1 萬 | 0.01% | +22,600+8.8% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 275,000 | $961.4 萬 | 0.02% | −225,000−45.0% | 減碼 |
| Privium Fund Management B.V. | 266,794 | $932.7 萬 | 2.11% | +16,050+6.4% | 加碼 |
| BNP Paribas Arbitrage, SA | 254,521 | $889.8 萬 | 0.01% | +79,193+45.2% | 加碼 |
| Artisan Partners Limited Partnership | 252,635 | $883.2 萬 | 0.01% | −1,987,820−88.7% | 減碼 |
| Siren, L.L.C. | 250,000 | $874.0 萬 | 0.39% | 00.0% | 不變 |
| CI Private Wealth, LLC | 239,163 | $836.1 萬 | 0.01% | +2,087+0.9% | 加碼 |
| Rafferty Asset Management, LLC | 237,337 | $829.7 萬 | 0.03% | +38,578+19.4% | 加碼 |
| Sector Gamma AS | 235,842 | $824.5 萬 | 2.83% | +25,000+11.9% | 加碼 |
| Aquatic Capital Management LLC | 230,016 | $804.1 萬 | 0.22% | +230,016 | 新進 |
| Kennedy Capital Management, Inc. | 223,278 | $780.6 萬 | 0.17% | +61,202+37.8% | 加碼 |
| Orion Investment Co | 216,000 | $755.1 萬 | 3.03% | −2,525−1.2% | 減碼 |
| Eversept Partners, LP | 214,952 | $751.5 萬 | 0.78% | −256,403−54.4% | 減碼 |
| Susquehanna Fundamental Investments, LLC | 213,015 | $744.7 萬 | 0.12% | +213,015 | 新進 |
| Rhenman & Partners Asset Management AB | 212,500 | $742.9 萬 | 0.76% | +17,500+9.0% | 加碼 |
| Stifel Financial Corp | 211,493 | $739.4 萬 | 0.01% | +28,988+15.9% | 加碼 |
| Renaissance Technologies LLC | 205,514 | $718.5 萬 | 0.01% | +15,000+7.9% | 加碼 |
| Verition Fund Management LLC | 200,184 | $699.8 萬 | 0.04% | +200,184 | 新進 |
| California Public Employees Retirement System | 192,130 | $671.7 萬 | 0.00% | −19,626−9.3% | 減碼 |
| Rhumbline Advisers | 191,893 | $670.9 萬 | 0.01% | −5,049−2.6% | 減碼 |
| GW&K Investment Management, LLC | 187,220 | $654.5 萬 | 0.06% | +187,220 | 新進 |
| Sicart Associates LLC | 185,821 | $649.6 萬 | 2.32% | −5,702−3.0% | 減碼 |
| Driehaus Capital Management LLC | 180,002 | $629.3 萬 | 0.05% | −49,967−21.7% | 減碼 |
| Citigroup Inc | 169,155 | $591.4 萬 | 0.01% | +98,860+140.6% | 加碼 |
| Legal & General Group Plc | 168,080 | $587.6 萬 | 0.00% | +10,793+6.9% | 加碼 |
| Squarepoint Ops LLC | 166,468 | $582.0 萬 | 0.01% | +39,127+30.7% | 加碼 |
| Jane Street Group, LLC | 164,634 | $575.6 萬 | 0.01% | −11,926−6.8% | 減碼 |
| Sovran Advisors, LLC | 171,812 | $561.7 萬 | 0.80% | +171,812 | 新進 |
| Sumitomo Mitsui Trust Holdings, Inc. | 156,657 | $547.7 萬 | 0.00% | −39,457−20.1% | 減碼 |
| Nikko Asset Management Americas, Inc. | 156,657 | $547.2 萬 | 0.06% | −39,457−20.1% | 減碼 |
| State Board of Administration of Florida Retirement System | 152,315 | $532.5 萬 | 0.01% | +1,260+0.8% | 加碼 |
| BLB&B Advisors, LLC | 152,050 | $531.6 萬 | 0.27% | −200−0.1% | 減碼 |
| Alyeska Investment Group, L.P. | 150,000 | $524.4 萬 | 0.02% | −18,951−11.2% | 減碼 |
| Tang Capital Management LLC | 150,000 | $524.4 萬 | 0.35% | 00.0% | 不變 |
| Sonora Investment Management Group, LLC | 148,776 | $520.1 萬 | 0.40% | −4,399−2.9% | 減碼 |
| Assenagon Asset Management S.A. | 141,917 | $496.1 萬 | 0.01% | +128,619+967.2% | 加碼 |
| California State Teachers Retirement System | 133,902 | $468.1 萬 | 0.01% | +7,722+6.1% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 125,389 | $438.4 萬 | 0.02% | +107,648+606.8% | 加碼 |
| Nicola Wealth Management Ltd. | 87,000 | $437.3 萬 | 0.41% | 00.0% | 不變 |
| Swedbank AB | 124,237 | $434.3 萬 | 0.01% | −5,136−4.0% | 減碼 |
| Woodline Partners LP | 107,610 | $376.2 萬 | 0.03% | +107,610 | 新進 |