Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2026 年第 2 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 515
- 較 2026 年第 1 季 +21 家
- 持有股數
- 1.80 億
- 較 2026 年第 1 季 +718.6 萬 (+4.2%)
- 總市值
- $142.6 億
- 較 2026 年第 1 季 +$13.0 億 (+10.0%)
- 新進機構
- 67
- 另有 199 家加碼
- 清倉機構
- 46
- 另有 162 家減碼
另有 3 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2026 年第 2 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 24,631,956 | $19.5 億 | 0.08% | +75,319+0.3% | 加碼 |
| Capital World Investors | 21,669,226 | $17.2 億 | 0.20% | +482,857+2.3% | 加碼 |
| BlackRock, Inc. | 10,704,660 | $8.49 億 | 0.01% | +262,184+2.5% | 加碼 |
| Vanguard Portfolio Management LLC | 7,859,529 | $6.23 億 | 0.03% | +50,627+0.6% | 加碼 |
| Wellington Management Group LLP | 7,651,415 | $6.07 億 | 0.10% | +1,259,599+19.7% | 加碼 |
| Vanguard Capital Management LLC | 7,211,497 | $5.72 億 | 0.01% | +93,167+1.3% | 加碼 |
| Two Sigma Investments, LP | 6,252,342 | $4.96 億 | 0.37% | +394,713+6.7% | 加碼 |
| Royal Bank of Canada | 6,182,479 | $4.90 億 | 0.08% | +2,380,664+62.6% | 加碼 |
| State Street Corp | 4,334,848 | $3.44 億 | 0.01% | +339,284+8.5% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 3,959,372 | $3.14 億 | 0.21% | −2,199,655−35.7% | 減碼 |
| Geode Capital Management, LLC | 3,584,024 | $2.95 億 | 0.02% | −400,308−10.0% | 減碼 |
| Price T Rowe Associates Inc | 3,184,500 | $2.52 億 | 0.03% | +159,249+5.3% | 加碼 |
| JPMorgan Chase & Co | 2,671,717 | $2.16 億 | 0.01% | +308,150+13.0% | 加碼 |
| Artisan Partners Limited Partnership | 2,640,024 | $2.09 億 | 0.34% | +581,716+28.3% | 加碼 |
| Tweedy, Browne Co LLC | 2,280,311 | $1.81 億 | 13.70% | +4,686+0.2% | 加碼 |
| Deep Track Capital, LP | 2,200,000 | $1.74 億 | 2.57% | +250,000+12.8% | 加碼 |
| Goldman Sachs Group Inc | 2,109,945 | $1.67 億 | 0.02% | +410,098+24.1% | 加碼 |
| Baker Bros. Advisors LP | 2,047,727 | $1.62 億 | 0.81% | 00.0% | 不變 |
| Deerfield Management Company, L.P. (Series C) | 1,979,669 | $1.57 億 | 1.64% | 00.0% | 不變 |
| American Century Companies Inc | 1,947,076 | $1.54 億 | 0.07% | +283,273+17.0% | 加碼 |
| Franklin Resources Inc | 1,623,377 | $1.29 億 | 0.03% | +48,354+3.1% | 加碼 |
| Charles Schwab Investment Management Inc | 1,605,054 | $1.27 億 | 0.02% | +21,788+1.4% | 加碼 |
| Barclays PLC | 1,603,136 | $1.27 億 | 0.04% | +1,313,262+453.0% | 加碼 |
| Pictet Asset Management Holding SA | 1,596,998 | $1.27 億 | 0.12% | +162,003+11.3% | 加碼 |
| UBS Asset Management Americas Inc | 1,454,672 | $1.15 億 | 0.02% | −20,960−1.4% | 減碼 |
| Polar Capital Holdings Plc | 1,454,021 | $1.15 億 | 0.33% | +624,510+75.3% | 加碼 |
| Alyeska Investment Group, L.P. | 1,417,916 | $1.12 億 | 0.29% | +944,766+199.7% | 加碼 |
| Nomura Asset Management International Inc. | 1,300,392 | $1.03 億 | 0.15% | +515,111+65.6% | 加碼 |
| Morgan Stanley | 1,281,444 | $1.02 億 | 0.01% | +254,935+24.8% | 加碼 |
| Invesco Ltd. | 1,120,707 | $8,886 萬 | 0.01% | −156,651−12.3% | 減碼 |
| Vanguard Fiduciary Trust Co | 1,060,845 | $8,411 萬 | 0.02% | +36,468+3.6% | 加碼 |
| Bellevue Group AG | 972,258 | $7,709 萬 | 1.62% | −846,407−46.5% | 減碼 |
| Groupama Asset Managment | 937,083 | $7,520 萬 | 0.95% | +112,543+13.6% | 加碼 |
| Northern Trust Corp | 913,610 | $7,244 萬 | 0.01% | +45,431+5.2% | 加碼 |
| Capital International Investors | 823,764 | $6,532 萬 | 0.01% | +823,764 | 新進 |
| Davern Capital Partners, LP | 798,709 | $6,333 萬 | 10.80% | +411,806+106.4% | 加碼 |
| Bank of America Corp | 790,990 | $6,272 萬 | 0.00% | −49,608−5.9% | 減碼 |
| Summit Partners Public Asset Management, LLC | 787,263 | $6,242 萬 | 1.62% | −616,770−43.9% | 減碼 |
| GW&K Investment Management, LLC | 746,966 | $5,923 萬 | 0.46% | −32,383−4.2% | 減碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 734,219 | $5,822 萬 | 0.06% | −173,314−19.1% | 減碼 |
| Nuveen, LLC | 726,282 | $5,759 萬 | 0.01% | +77,786+12.0% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 684,236 | $5,425 萬 | 0.10% | −189,853−21.7% | 減碼 |
| Eversept Partners, LP | 664,684 | $5,270 萬 | 2.87% | +32,584+5.2% | 加碼 |
| Voloridge Investment Management, LLC | 655,454 | $5,197 萬 | 0.22% | −17,404−2.6% | 減碼 |
| Massachusetts Financial Services Co | 651,816 | $5,168 萬 | 0.02% | −14,300−2.1% | 減碼 |
| Neuberger Berman Group LLC | 633,533 | $5,023 萬 | 0.03% | +190,261+42.9% | 加碼 |
| Arrowstreet Capital, Limited Partnership | 632,028 | $5,011 萬 | 0.02% | −105,831−14.3% | 減碼 |
| UBS Group AG | 624,874 | $4,955 萬 | 0.01% | −183,569−22.7% | 減碼 |
| TimesSquare Capital Management, LLC | 614,070 | $4,869 萬 | 0.72% | +338,396+122.8% | 加碼 |
| Eventide Asset Management, LLC | 575,000 | $4,559 萬 | 0.61% | 00.0% | 不變 |
| Perceptive Advisors LLC | 566,000 | $4,488 萬 | 0.70% | +62,000+12.3% | 加碼 |
| Renaissance Technologies LLC | 559,414 | $4,436 萬 | 0.06% | +253,865+83.1% | 加碼 |
| Bank of New York Mellon Corp | 542,454 | $4,301 萬 | 0.01% | +27,837+5.4% | 加碼 |
| Teacher Retirement System of Texas | 522,317 | $4,141 萬 | 0.11% | −1,615−0.3% | 減碼 |
| Boone Capital Management LLC | 519,977 | $4,123 萬 | 9.64% | +19,455+3.9% | 加碼 |
| Jane Street Group, LLC | 503,647 | $3,993 萬 | 0.03% | +311,829+162.6% | 加碼 |
| New York State Common Retirement Fund | 500,050 | $3,965 萬 | 0.05% | +149,636+42.7% | 加碼 |
| BNP Paribas Arbitrage, SA | 454,649 | $3,605 萬 | 0.02% | −24,811−5.2% | 減碼 |
| Candriam Luxembourg S.C.A. | 445,019 | $3,525 萬 | 0.16% | −39,034−8.1% | 減碼 |
| First Trust Advisors LP | 427,197 | $3,387 萬 | 0.02% | −41,166−8.8% | 減碼 |
| Pinnacle Associates Ltd | 419,752 | $3,328 萬 | 0.36% | −16,705−3.8% | 減碼 |
| Nomura Holdings Inc | 402,192 | $3,189 萬 | 0.13% | +288,112+252.6% | 加碼 |
| Handelsbanken Fonder AB | 383,211 | $3,039 萬 | 0.09% | +169,300+79.1% | 加碼 |
| C WorldWide Group Holding A/S | 366,000 | $2,902 萬 | 0.70% | 00.0% | 不變 |
| TD Asset Management Inc | 340,548 | $2,700 萬 | 0.02% | −189,406−35.7% | 減碼 |
| Freestone Grove Partners LP | 339,967 | $2,696 萬 | 0.18% | +339,967 | 新進 |
| Qube Research & Technologies Ltd | 333,952 | $2,648 萬 | 0.03% | +291,096+679.2% | 加碼 |
| Capital Research Global Investors | 331,936 | $2,632 萬 | 0.00% | +8,921+2.8% | 加碼 |
| Capital Fund Management S.A. | 329,554 | $2,613 萬 | 0.19% | +187,353+131.8% | 加碼 |
| Alliancebernstein L.P. | 340,450 | $2,556 萬 | 0.01% | −60,219−15.0% | 減碼 |
| Carmignac Gestion | 321,000 | $2,545 萬 | 0.33% | +268,000+505.7% | 加碼 |
| Privium Fund Management B.V. | 319,924 | $2,537 萬 | 4.66% | +29,900+10.3% | 加碼 |
| Swiss National Bank | 315,000 | $2,498 萬 | 0.01% | +10,500+3.4% | 加碼 |
| Jump Financial, LLC | 306,330 | $2,429 萬 | 0.22% | +99,655+48.2% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 300,770 | $2,385 萬 | 0.15% | +12,054+4.2% | 加碼 |
| Legal & General Group Plc | 299,184 | $2,372 萬 | 0.00% | +4,505+1.5% | 加碼 |
| D. E. Shaw & Co., Inc. | 297,041 | $2,355 萬 | 0.01% | −132,558−30.9% | 減碼 |
| Millennium Management LLC | 288,872 | $2,290 萬 | 0.02% | −762,634−72.5% | 減碼 |
| Davenport & Co LLC | 283,960 | $2,252 萬 | 0.11% | +45,722+19.2% | 加碼 |
| Standard Life Aberdeen plc | 277,400 | $2,200 萬 | 0.03% | +163,557+143.7% | 加碼 |
| California Public Employees Retirement System | 270,843 | $2,148 萬 | 0.01% | +15,358+6.0% | 加碼 |
| Tocqueville Asset Management L.P. | 251,215 | $1,992 萬 | 0.26% | +31,995+14.6% | 加碼 |
| Raymond James Financial Inc | 237,348 | $1,882 萬 | 0.01% | +2,227+0.9% | 加碼 |
| Citadel Advisors LLC | 236,284 | $1,873 萬 | 0.01% | −706,250−74.9% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 233,499 | $1,851 萬 | 0.03% | +13,847+6.3% | 加碼 |
| Wells Fargo & Company | 226,213 | $1,794 萬 | 0.00% | +36,360+19.2% | 加碼 |
| Empowered Funds, LLC | 223,142 | $1,769 萬 | 0.09% | +120,001+116.3% | 加碼 |
| Orion Investment Co | 220,335 | $1,747 萬 | 5.12% | −4,680−2.1% | 減碼 |
| Life Cycle Investment Partners Ltd | 219,896 | $1,744 萬 | 0.08% | +219,896 | 新進 |
| Algert Global LLC | 206,853 | $1,640 萬 | 0.19% | +90,290+77.5% | 加碼 |
| Stifel Financial Corp | 202,983 | $1,609 萬 | 0.01% | +6,280+3.2% | 加碼 |
| CI Private Wealth, LLC | 196,661 | $1,559 萬 | 0.02% | +620.0% | 加碼 |
| Eagle Health Investments LP | 194,577 | $1,543 萬 | 2.56% | +194,577 | 新進 |
| HSBC Holdings PLC | 188,402 | $1,505 萬 | 0.01% | +2,435+1.3% | 加碼 |
| Sector Gamma AS | 189,468 | $1,502 萬 | 3.26% | +20,000+11.8% | 加碼 |
| California State Teachers Retirement System | 180,949 | $1,435 萬 | 0.01% | +4,464+2.5% | 加碼 |
| Polymer Capital Management (HK) LTD | 177,897 | $1,411 萬 | 1.43% | +116,697+190.7% | 加碼 |
| Deutsche Bank AG | 169,614 | $1,345 萬 | 0.00% | +9,723+6.1% | 加碼 |
| ADAR1 Capital Management, LLC | 166,286 | $1,318 萬 | 0.62% | +5,948+3.7% | 加碼 |
| Rhumbline Advisers | 164,911 | $1,308 萬 | 0.01% | −8,529−4.9% | 減碼 |