Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 3 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 437
- 較 2025 年第 2 季 +78 家
- 持有股數
- 1.68 億
- 較 2025 年第 2 季 −22.1 萬 (−0.1%)
- 總市值
- $110.1 億
- 較 2025 年第 2 季 +$43.6 億 (+65.5%)
- 新進機構
- 115
- 另有 136 家加碼
- 清倉機構
- 37
- 另有 116 家減碼
另有 4 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 3 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 23,689,038 | $15.5 億 | 0.08% | +46,048+0.2% | 加碼 |
| Vanguard Group Inc | 16,481,730 | $10.8 億 | 0.02% | −233,116−1.4% | 減碼 |
| T. Rowe Price Investment Management, Inc. | 13,156,929 | $8.61 億 | 0.53% | −2,891,792−18.0% | 減碼 |
| Capital World Investors | 12,722,728 | $8.32 億 | 0.11% | +182,540+1.5% | 加碼 |
| BlackRock, Inc. | 10,447,940 | $6.84 億 | 0.01% | −448,997−4.1% | 減碼 |
| Wellington Management Group LLP | 6,588,811 | $4.31 億 | 0.08% | +243,035+3.8% | 加碼 |
| Bellevue Group AG | 6,244,451 | $4.09 億 | 8.49% | −1,608,747−20.5% | 減碼 |
| State Street Corp | 4,388,651 | $2.87 億 | 0.01% | −141,747−3.1% | 減碼 |
| Deep Track Capital, LP | 3,808,144 | $2.49 億 | 6.95% | −1,083,400−22.1% | 減碼 |
| Geode Capital Management, LLC | 3,066,289 | $2.01 億 | 0.01% | +175,194+6.1% | 加碼 |
| Tweedy, Browne Co LLC | 2,901,216 | $1.90 億 | 16.48% | +9,268+0.3% | 加碼 |
| Price T Rowe Associates Inc | 2,729,685 | $1.79 億 | 0.02% | −396,388−12.7% | 減碼 |
| Citadel Advisors LLC | 2,402,065 | $1.57 億 | 0.13% | +907,084+60.7% | 加碼 |
| Two Sigma Advisers, LP | 2,073,111 | $1.36 億 | 0.27% | −594,500−22.3% | 減碼 |
| Deerfield Management Company, L.P. (Series C) | 1,979,669 | $1.30 億 | 1.98% | +1,979,669 | 新進 |
| Two Sigma Investments, LP | 1,575,943 | $1.03 億 | 0.16% | −212,424−11.9% | 減碼 |
| Charles Schwab Investment Management Inc | 1,519,951 | $9,944 萬 | 0.02% | +32,133+2.2% | 加碼 |
| Pictet Asset Management Holding SA | 1,393,124 | $9,048 萬 | 0.09% | +784,484+128.9% | 加碼 |
| American Century Companies Inc | 1,372,225 | $8,977 萬 | 0.05% | +899,476+190.3% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,315,000 | $8,603 萬 | 0.14% | −2,485,000−65.4% | 減碼 |
| Royal Bank of Canada | 1,226,624 | $8,024 萬 | 0.01% | +426,712+53.3% | 加碼 |
| Morgan Stanley | 1,180,316 | $7,722 萬 | 0.00% | −181,893−13.4% | 減碼 |
| UBS Asset Management Americas Inc | 1,154,166 | $7,551 萬 | 0.02% | +363,094+45.9% | 加碼 |
| Macquarie Group Ltd | 1,131,936 | $7,405 萬 | 0.09% | −302,137−21.1% | 減碼 |
| Vestal Point Capital, LP | 1,075,000 | $7,033 萬 | 3.19% | +575,000+115.0% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,059,721 | $6,932 萬 | 0.18% | −291,158−21.6% | 減碼 |
| UBS Group AG | 1,046,990 | $6,849 萬 | 0.01% | −482,333−31.5% | 減碼 |
| Polar Capital Holdings Plc | 1,033,622 | $6,762 萬 | 0.33% | +33,622+3.4% | 加碼 |
| TD Asset Management Inc | 960,272 | $6,282 萬 | 0.05% | −144,418−13.1% | 減碼 |
| Marshall Wace, LLP | 958,829 | $6,273 萬 | 0.07% | +945,729+7,219.3% | 加碼 |
| Artisan Partners Limited Partnership | 890,072 | $5,823 萬 | 0.08% | +535,110+150.8% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 878,155 | $5,745 萬 | 0.18% | +612,362+230.4% | 加碼 |
| Massachusetts Financial Services Co | 862,593 | $5,643 萬 | 0.02% | +343,409+66.1% | 加碼 |
| Bank of America Corp | 855,295 | $5,595 萬 | 0.00% | −140,595−14.1% | 減碼 |
| Northern Trust Corp | 844,943 | $5,528 萬 | 0.01% | +30,693+3.8% | 加碼 |
| Voloridge Investment Management, LLC | 803,047 | $5,254 萬 | 0.18% | −51,587−6.0% | 減碼 |
| Millennium Management LLC | 779,570 | $5,100 萬 | 0.04% | −1,869,957−70.6% | 減碼 |
| Goldman Sachs Group Inc | 777,570 | $5,087 萬 | 0.01% | −3700.0% | 減碼 |
| Ameriprise Financial Inc | 765,822 | $5,010 萬 | 0.01% | +397,703+108.0% | 加碼 |
| Balyasny Asset Management LLC | 760,111 | $4,973 萬 | 0.10% | −8,537−1.1% | 減碼 |
| Summit Partners Public Asset Management, LLC | 750,000 | $4,907 萬 | 1.60% | +750,000 | 新進 |
| Bank of Montreal | 747,402 | $4,890 萬 | 0.02% | +264,113+54.6% | 加碼 |
| Nomura Holdings Inc | 733,398 | $4,798 萬 | 0.22% | +701,237+2,180.4% | 加碼 |
| Barclays PLC | 714,048 | $4,671 萬 | 0.02% | +130,782+22.4% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 631,215 | $4,129 萬 | 0.25% | −269,103−29.9% | 減碼 |
| D. E. Shaw & Co., Inc. | 630,938 | $4,128 萬 | 0.03% | +630,938 | 新進 |
| Arrowstreet Capital, Limited Partnership | 630,136 | $4,122 萬 | 0.03% | +630,136 | 新進 |
| Candriam Luxembourg S.C.A. | 611,237 | $3,999 萬 | 0.21% | −113,503−15.7% | 減碼 |
| Groupama Asset Managment | 561,777 | $3,744 萬 | 0.55% | −99,180−15.0% | 減碼 |
| Baker Bros. Advisors LP | 566,798 | $3,708 萬 | 0.27% | +566,798 | 新進 |
| Tang Capital Management LLC | 550,000 | $3,598 萬 | 1.39% | +400,000+266.7% | 加碼 |
| JPMorgan Chase & Co | 544,468 | $3,562 萬 | 0.00% | +149,490+37.8% | 加碼 |
| Eversept Partners, LP | 538,661 | $3,524 萬 | 2.70% | −50,239−8.5% | 減碼 |
| Bank of New York Mellon Corp | 532,114 | $3,481 萬 | 0.01% | +4,926+0.9% | 加碼 |
| Invesco Ltd. | 519,070 | $3,396 萬 | 0.01% | +262,835+102.6% | 加碼 |
| Hudson Bay Capital Management LP | 515,000 | $3,369 萬 | 0.20% | −235,000−31.3% | 減碼 |
| Renaissance Technologies LLC | 486,714 | $3,184 萬 | 0.04% | +216,000+79.8% | 加碼 |
| Pinnacle Associates Ltd | 481,751 | $3,152 萬 | 0.42% | −12,788−2.6% | 減碼 |
| Teacher Retirement System of Texas | 473,945 | $3,101 萬 | 0.12% | −194,328−29.1% | 減碼 |
| C WorldWide Group Holding A/S | 426,000 | $2,787 萬 | 0.43% | −24,000−5.3% | 減碼 |
| Susquehanna International Group, LLP | 420,950 | $2,754 萬 | 0.04% | +420,950 | 新進 |
| Boone Capital Management LLC | 417,833 | $2,733 萬 | 8.96% | +417,833 | 新進 |
| Nuveen, LLC | 415,618 | $2,719 萬 | 0.01% | +170,533+69.6% | 加碼 |
| Ikarian Capital, LLC | 415,163 | $2,716 萬 | 6.15% | +415,163 | 新進 |
| AXA Investment Managers S.A. | 406,451 | $2,659 萬 | 0.07% | +406,451 | 新進 |
| Squarepoint Ops LLC | 383,792 | $2,511 萬 | 0.05% | +249,397+185.6% | 加碼 |
| BNP Paribas Arbitrage, SA | 383,226 | $2,507 萬 | 0.02% | +205,464+115.6% | 加碼 |
| Jane Street Group, LLC | 365,070 | $2,388 萬 | 0.03% | +365,070 | 新進 |
| Man Group plc | 333,820 | $2,184 萬 | 0.04% | +324,851+3,621.9% | 加碼 |
| Legal & General Group Plc | 319,565 | $2,091 萬 | 0.00% | −84,801−21.0% | 減碼 |
| Assenagon Asset Management S.A. | 312,297 | $2,043 萬 | 0.03% | +294,643+1,669.0% | 加碼 |
| Alyeska Investment Group, L.P. | 311,258 | $2,036 萬 | 0.06% | +152,250+95.7% | 加碼 |
| Rhenman & Partners Asset Management AB | 310,000 | $2,028 萬 | 2.24% | +128,000+70.3% | 加碼 |
| Swiss National Bank | 293,100 | $1,917 萬 | 0.01% | +4,500+1.6% | 加碼 |
| Wells Fargo & Company | 285,293 | $1,866 萬 | 0.00% | +75,436+35.9% | 加碼 |
| Sector Gamma AS | 270,963 | $1,773 萬 | 4.40% | −14,879−5.2% | 減碼 |
| GW&K Investment Management, LLC | 264,007 | $1,727 萬 | 0.15% | −184,823−41.2% | 減碼 |
| Algert Global LLC | 252,281 | $1,650 萬 | 0.28% | +214,191+562.3% | 加碼 |
| Privium Fund Management B.V. | 248,894 | $1,628 萬 | 2.93% | −18,700−7.0% | 減碼 |
| Raymond James Financial Inc | 240,424 | $1,573 萬 | 0.01% | +29,832+14.2% | 加碼 |
| Jain Global LLC | 225,739 | $1,477 萬 | 0.19% | +218,544+3,037.4% | 加碼 |
| Orion Investment Co | 224,705 | $1,470 萬 | 4.70% | +7,335+3.4% | 加碼 |
| California Public Employees Retirement System | 215,845 | $1,412 萬 | 0.01% | +13,852+6.9% | 加碼 |
| Trexquant Investment LP | 215,121 | $1,407 萬 | 0.15% | +86,252+66.9% | 加碼 |
| Stifel Financial Corp | 202,628 | $1,326 萬 | 0.01% | +6,271+3.2% | 加碼 |
| Schonfeld Strategic Advisors LLC | 200,839 | $1,314 萬 | 0.09% | −248,367−55.3% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 197,434 | $1,292 萬 | 0.02% | +47,595+31.8% | 加碼 |
| Tocqueville Asset Management L.P. | 193,045 | $1,263 萬 | 0.18% | +5,700+3.0% | 加碼 |
| Great Lakes Advisors, LLC | 186,950 | $1,223 萬 | 0.10% | −212,696−53.2% | 減碼 |
| Rhumbline Advisers | 182,061 | $1,191 萬 | 0.01% | +462+0.3% | 加碼 |
| Cinctive Capital Management LP | 173,819 | $1,137 萬 | 0.57% | +173,819 | 新進 |
| Sovran Advisors, LLC | 150,856 | $1,119 萬 | 0.99% | −171,057−53.1% | 減碼 |
| Sonora Investment Management Group, LLC | 169,808 | $1,111 萬 | 0.79% | +6,636+4.1% | 加碼 |
| New York State Common Retirement Fund | 168,222 | $1,101 萬 | 0.01% | +81,250+93.4% | 加碼 |
| Sicart Associates LLC | 164,318 | $1,075 萬 | 2.91% | −20,978−11.3% | 減碼 |
| Boothbay Fund Management, LLC | 163,462 | $1,069 萬 | 0.28% | +163,462 | 新進 |
| Capricorn Fund Managers Ltd | 162,800 | $1,065 萬 | 3.58% | +162,800 | 新進 |
| Aquatic Capital Management LLC | 159,045 | $1,040 萬 | 0.19% | +959+0.6% | 加碼 |
| Edmond de Rothschild Holding S.A. | 156,690 | $1,025 萬 | 0.16% | −40,910−20.7% | 減碼 |
| Citigroup Inc | 155,853 | $1,020 萬 | 0.01% | −185,124−54.3% | 減碼 |