Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 3 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 437
- 較 2025 年第 2 季 +78 家
- 持有股數
- 1.68 億
- 較 2025 年第 2 季 −22.1 萬 (−0.1%)
- 總市值
- $110.1 億
- 較 2025 年第 2 季 +$43.6 億 (+65.5%)
- 新進機構
- 115
- 另有 136 家加碼
- 清倉機構
- 37
- 另有 116 家減碼
另有 4 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 3 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Skandinaviska Enskilda Banken AB (publ) | 155,790 | $1,019 萬 | 0.04% | +96,164+161.3% | 加碼 |
| ExodusPoint Capital Management, LP | 152,125 | $995.2 萬 | 0.14% | +152,125 | 新進 |
| Natixis | 145,286 | $950.5 萬 | 0.05% | +145,286 | 新進 |
| California State Teachers Retirement System | 145,112 | $949.3 萬 | 0.01% | +80.0% | 加碼 |
| State Board of Administration of Florida Retirement System | 143,534 | $939.0 萬 | 0.02% | −10,361−6.7% | 減碼 |
| Lombard Odier Asset Management (Europe) Ltd | – | $895.8 萬 | 0.46% | – | 新進 |
| ADAR1 Capital Management, LLC | 133,818 | $875.4 萬 | 0.87% | −14,643−9.9% | 減碼 |
| Exome Asset Management LLC | 131,016 | $857.1 萬 | 5.66% | +9,900+8.2% | 加碼 |
| Rafferty Asset Management, LLC | 125,773 | $822.8 萬 | 0.03% | −18,997−13.1% | 減碼 |
| Kennedy Capital Management, Inc. | 122,766 | $803.1 萬 | 0.18% | −9,279−7.0% | 減碼 |
| SEI Investments Co | 119,028 | $778.7 萬 | 0.01% | +20,680+21.0% | 加碼 |
| BLB&B Advisors, LLC | 118,600 | $775.9 萬 | 0.33% | −32,950−21.7% | 減碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 116,000 | $758.9 萬 | 0.01% | 00.0% | 不變 |
| Sumitomo Mitsui Trust Holdings, Inc. | 114,772 | $750.8 萬 | 0.00% | −24,967−17.9% | 減碼 |
| Neuberger Berman Group LLC | 114,743 | $750.6 萬 | 0.01% | +120+0.1% | 加碼 |
| Nikko Asset Management Americas, Inc. | 114,592 | $749.4 萬 | 0.07% | −25,147−18.0% | 減碼 |
| Van Eck Associates Corp | 111,819 | $731.6 萬 | 0.01% | +38,202+51.9% | 加碼 |
| Voya Investment Management LLC | 111,589 | $730.0 萬 | 0.01% | +47,072+73.0% | 加碼 |
| Acadian Asset Management LLC | 110,444 | $721.4 萬 | 0.01% | +110,444 | 新進 |
| DCF Advisers, LLC | 108,413 | $709.2 萬 | 2.69% | +16,663+18.2% | 加碼 |
| Amundi | 101,531 | $700.8 萬 | 0.00% | +101,531 | 新進 |
| Simplex Trading, LLC | 100,206 | $655.5 萬 | 0.14% | +60,568+152.8% | 加碼 |
| Manufacturers Life Insurance Company, The | 98,023 | $641.3 萬 | 0.01% | +14,637+17.6% | 加碼 |
| State of Wisconsin Investment Board | 96,837 | $633.5 萬 | 0.01% | +143+0.1% | 加碼 |
| J. Goldman & Co LP | 96,198 | $629.3 萬 | 0.24% | −51,484−34.9% | 減碼 |
| Susquehanna Portfolio Strategies, LLC | 95,960 | $627.8 萬 | 0.10% | +3,060+3.3% | 加碼 |
| Lisanti Capital Growth, LLC | 92,124 | $602.7 萬 | 1.47% | +92,124 | 新進 |
| DekaBank Deutsche Girozentrale | 93,807 | $598.7 萬 | 0.01% | 00.0% | 不變 |
| Deutsche Bank AG | 88,803 | $580.9 萬 | 0.00% | +3,525+4.1% | 加碼 |
| Standard Life Aberdeen plc | 87,924 | $575.2 萬 | 0.01% | −318,770−78.4% | 減碼 |
| Nicola Wealth Management Ltd. | 87,000 | $569.1 萬 | 0.51% | 00.0% | 不變 |
| Great Point Partners LLC | 80,000 | $523.4 萬 | 2.19% | −420,000−84.0% | 減碼 |
| Russell Investments Group, Ltd. | 77,293 | $505.7 萬 | 0.01% | +68,028+734.2% | 加碼 |
| First Trust Advisors LP | 75,224 | $492.1 萬 | 0.00% | +18,705+33.1% | 加碼 |
| Hillsdale Investment Management Inc. | 70,900 | $463.8 萬 | 0.14% | +70,900 | 新進 |
| Erste Asset Management GmbH | 71,800 | $460.6 萬 | 0.04% | +20,500+40.0% | 加碼 |
| Treasurer of the State of North Carolina | 69,862 | $457.0 萬 | 0.01% | −2,725−3.8% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 69,324 | $453.5 萬 | 0.04% | +9,601+16.1% | 加碼 |
| Janus Henderson Group PLC | 63,877 | $417.9 萬 | 0.00% | 00.0% | 不變 |
| Lazard Asset Management LLC | 63,791 | $417.3 萬 | 0.01% | +3,042+5.0% | 加碼 |
| Davenport & Co LLC | 62,563 | $409.3 萬 | 0.02% | −2,280−3.5% | 減碼 |
| Artia Global Partners LP | 60,176 | $393.7 萬 | 0.69% | +60,176 | 新進 |
| State of New Jersey Common Pension Fund D | 59,817 | $391.3 萬 | 0.01% | +899+1.5% | 加碼 |
| Alpine Global Management, LLC | 55,900 | $365.7 萬 | 0.75% | +30,463+119.8% | 加碼 |
| PDT Partners, LLC | 54,365 | $355.7 萬 | 0.22% | 00.0% | 不變 |
| Alliancebernstein L.P. | 54,262 | $355.0 萬 | 0.00% | +2,205+4.2% | 加碼 |
| EAM Investors, LLC | 54,977 | $353.8 萬 | 0.41% | +54,977 | 新進 |
| Handelsbanken Fonder AB | 51,911 | $339.6 萬 | 0.01% | +8,700+20.1% | 加碼 |
| Creative Planning | 51,474 | $336.7 萬 | 0.00% | −1,815−3.4% | 減碼 |
| Capital Counsel LLC | 49,605 | $324.5 萬 | 0.12% | −600−1.2% | 減碼 |
| Raiffeisen Bank International AG | 50,000 | $320.8 萬 | 0.04% | −6,754−11.9% | 減碼 |
| Cubist Systematic Strategies, LLC | 48,654 | $318.3 萬 | 0.04% | +48,654 | 新進 |
| Public Employees Retirement System of Ohio | 48,545 | $317.6 萬 | 0.01% | +301+0.6% | 加碼 |
| Point72 Hong Kong Ltd | 47,517 | $310.9 萬 | 0.14% | +47,517 | 新進 |
| Dark Forest Capital Management LP | 46,092 | $301.5 萬 | 0.11% | +46,092 | 新進 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 45,220 | $295.8 萬 | 0.01% | +1,605+3.7% | 加碼 |
| Great West Life Assurance Co | 46,128 | $295.8 萬 | 0.00% | −373−0.8% | 減碼 |
| HSBC Holdings PLC | 45,456 | $294.7 萬 | 0.00% | −62,838−58.0% | 減碼 |
| Arizona State Retirement System | 44,731 | $292.6 萬 | 0.02% | +691+1.6% | 加碼 |
| Bridgewater Associates, LP | 43,578 | $285.1 萬 | 0.01% | +43,578 | 新進 |
| Fred Alger Management, LLC | 42,401 | $277.4 萬 | 0.01% | +32,937+348.0% | 加碼 |
| Dimensional Fund Advisors LP | 42,217 | $276.2 萬 | 0.00% | +42,217 | 新進 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $274.8 萬 | 0.30% | 00.0% | 不變 |
| Grandfield & Dodd, LLC | 37,675 | $246.5 萬 | 0.14% | +445+1.2% | 加碼 |
| LMR Partners LLP | 37,600 | $246.0 萬 | 0.03% | +37,600 | 新進 |
| Prelude Capital Management, LLC | 37,293 | $244.0 萬 | 0.19% | −2,130−5.4% | 減碼 |
| Verition Fund Management LLC | 37,196 | $243.3 萬 | 0.01% | −195,491−84.0% | 減碼 |
| One Capital Management, LLC | 36,426 | $238.3 萬 | 0.08% | +6,561+22.0% | 加碼 |
| Future Fund LLC | 36,156 | $236.5 萬 | 0.83% | +6,561+22.2% | 加碼 |
| Quantinno Capital Management LP | 36,115 | $236.3 萬 | 0.01% | +18,573+105.9% | 加碼 |
| Stanley-Laman Group, Ltd. | 35,774 | $234.0 萬 | 0.33% | +35,774 | 新進 |
| Guggenheim Capital LLC | 35,357 | $231.3 萬 | 0.02% | −5,500−13.5% | 減碼 |
| Blair William & Co | 34,371 | $224.9 萬 | 0.01% | −3,520−9.3% | 減碼 |
| Pathstone Holdings, LLC | 33,602 | $219.8 萬 | 0.01% | +2,843+9.2% | 加碼 |
| Entropy Technologies, LP | 32,925 | $215.4 萬 | 0.16% | +3,473+11.8% | 加碼 |
| Gotham Asset Management, LLC | 32,152 | $210.3 萬 | 0.01% | +17,873+125.2% | 加碼 |
| KLP Kapitalforvaltning AS | 31,500 | $206.1 萬 | 0.01% | 00.0% | 不變 |
| Twin Tree Management, LP | 28,575 | $186.9 萬 | 0.09% | +28,575 | 新進 |
| Granite Investment Partners, LLC | 28,033 | $183.4 萬 | 0.10% | −15,148−35.1% | 減碼 |
| China Universal Asset Management Co., Ltd. | 27,939 | $182.8 萬 | 0.15% | −4,027−12.6% | 減碼 |
| Ensign Peak Advisors, Inc | 27,595 | $180.5 萬 | 0.00% | −25,725−48.2% | 減碼 |
| Envestnet Asset Management Inc | 27,509 | $180.0 萬 | 0.00% | +13,965+103.1% | 加碼 |
| Wolverine Trading, LLC | 27,585 | $177.0 萬 | 0.04% | +27,585 | 新進 |
| Landscape Capital Management, L.L.C. | 26,562 | $173.8 萬 | 0.11% | +26,562 | 新進 |
| Profund Advisors LLC | 25,932 | $169.6 萬 | 0.06% | −2,927−10.1% | 減碼 |
| Calamos Advisors LLC | 25,863 | $169.2 萬 | 0.01% | +25,863 | 新進 |
| Engineers Gate Manager LP | 25,779 | $168.6 萬 | 0.02% | −7,339−22.2% | 減碼 |
| Bamco Inc | 25,000 | $163.6 萬 | 0.00% | +25,000 | 新進 |
| Bayesian Capital Management, LP | 24,715 | $161.7 萬 | 0.33% | +8,115+48.9% | 加碼 |
| Daiwa Securities Group Inc. | 24,701 | $161.6 萬 | 0.01% | −1,440−5.5% | 減碼 |
| LPL Financial LLC | 24,463 | $160.0 萬 | 0.00% | −409−1.6% | 減碼 |
| Mariner, LLC | 24,227 | $158.5 萬 | 0.00% | −12,687−34.4% | 減碼 |
| Teachers Retirement System of the State of Kentucky | 24,083 | $157.6 萬 | 0.01% | 00.0% | 不變 |
| BlueCrest Capital Management Ltd | 23,370 | $152.9 萬 | 0.09% | +23,370 | 新進 |
| Atika Capital Management LLC | 21,500 | $140.7 萬 | 0.12% | +21,500 | 新進 |
| Xponance, Inc. | 21,450 | $140.3 萬 | 0.01% | −1,304−5.7% | 減碼 |
| Nicollet Investment Management, Inc. | 20,408 | $133.5 萬 | 0.44% | −339−1.6% | 減碼 |
| Resolute Capital Asset Partners LLC | 20,000 | $130.8 萬 | 0.68% | +20,000 | 新進 |
| Dana Investment Advisors, Inc. | 18,818 | $123.1 萬 | 0.04% | +18,818 | 新進 |
| Victory Capital Management Inc | 18,211 | $119.1 萬 | 0.00% | −305−1.6% | 減碼 |