Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 1 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 344
- 較 2024 年第 4 季 −6 家
- 持有股數
- 1.67 億
- 較 2024 年第 4 季 +668.6 萬 (+4.2%)
- 總市值
- $50.3 億
- 較 2024 年第 4 季 −$5.65 億 (−10.1%)
- 新進機構
- 54
- 另有 102 家加碼
- 清倉機構
- 60
- 另有 123 家減碼
另有 6 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 1 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2024 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 23,613,585 | $7.12 億 | 0.05% | +924,094+4.1% | 加碼 |
| Vanguard Group Inc | 16,383,934 | $4.94 億 | 0.01% | −88,605−0.5% | 減碼 |
| T. Rowe Price Investment Management, Inc. | 16,175,533 | $4.88 億 | 0.32% | +2,006,334+14.2% | 加碼 |
| Capital World Investors | 12,361,994 | $3.73 億 | 0.06% | +896,581+7.8% | 加碼 |
| BlackRock, Inc. | 11,264,442 | $3.40 億 | 0.01% | −401,106−3.4% | 減碼 |
| Wellington Management Group LLP | 8,416,421 | $2.54 億 | 0.05% | −255,727−2.9% | 減碼 |
| Bellevue Group AG | 7,853,198 | $2.37 億 | 5.31% | −15,502−0.2% | 減碼 |
| State Street Corp | 4,845,133 | $1.46 億 | 0.01% | −581,280−10.7% | 減碼 |
| Deep Track Capital, LP | 4,564,207 | $1.38 億 | 4.46% | +2,630,279+136.0% | 加碼 |
| Citadel Advisors LLC | 3,480,062 | $1.05 億 | 0.10% | +1,314,146+60.7% | 加碼 |
| Price T Rowe Associates Inc | 3,265,034 | $9,851 萬 | 0.01% | −561,905−14.7% | 減碼 |
| Tweedy, Browne Co LLC | 2,983,518 | $9,001 萬 | 7.98% | −265,345−8.2% | 減碼 |
| Geode Capital Management, LLC | 2,842,954 | $8,580 萬 | 0.01% | +155,706+5.8% | 加碼 |
| OrbiMed Advisors LLC | 2,540,136 | $7,664 萬 | 1.84% | −277,211−9.8% | 減碼 |
| Two Sigma Advisers, LP | 2,092,011 | $6,312 萬 | 0.14% | +742,800+55.1% | 加碼 |
| BVF Inc | 1,913,385 | $5,773 萬 | 2.35% | +1,913,385 | 新進 |
| UBS Group AG | 1,890,602 | $5,704 萬 | 0.01% | −27,006−1.4% | 減碼 |
| Two Sigma Investments, LP | 1,685,853 | $5,086 萬 | 0.11% | +764,414+83.0% | 加碼 |
| Macquarie Group Ltd | 1,667,194 | $5,030 萬 | 0.06% | −102,549−5.8% | 減碼 |
| Charles Schwab Investment Management Inc | 1,443,629 | $4,355 萬 | 0.01% | −37,811−2.6% | 減碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,196,392 | $3,610 萬 | 0.10% | +116,051+10.7% | 加碼 |
| Morgan Stanley | 1,144,181 | $3,452 萬 | 0.00% | −185,748−14.0% | 減碼 |
| TD Asset Management Inc | 1,100,466 | $3,320 萬 | 0.03% | +50,476+4.8% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,075,600 | $3,245 萬 | 0.06% | +800,600+291.1% | 加碼 |
| Hudson Bay Capital Management LP | 1,049,900 | $3,168 萬 | 0.20% | +228,700+27.8% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 1,000,527 | $3,019 萬 | 0.30% | −24,733−2.4% | 減碼 |
| Candriam Luxembourg S.C.A. | 993,704 | $2,998 萬 | 0.19% | +143,880+16.9% | 加碼 |
| Invesco Ltd. | 874,834 | $2,639 萬 | 0.01% | +86,235+10.9% | 加碼 |
| Norges Bank | 858,228 | $2,589 萬 | 0.00% | −856,534−50.0% | 減碼 |
| Northern Trust Corp | 834,847 | $2,519 萬 | 0.00% | −5,424−0.6% | 減碼 |
| Bank of Montreal | 782,835 | $2,362 萬 | 0.01% | +470,689+150.8% | 加碼 |
| Bank of America Corp | 767,432 | $2,315 萬 | 0.00% | +344,571+81.5% | 加碼 |
| Camber Capital Management LP | 725,000 | $2,187 萬 | 1.36% | +100,000+16.0% | 加碼 |
| UBS Asset Management Americas Inc | 659,435 | $1,990 萬 | 0.01% | +39,794+6.4% | 加碼 |
| Goldman Sachs Group Inc | 652,518 | $1,969 萬 | 0.00% | +274,310+72.5% | 加碼 |
| Pictet Asset Management Holding SA | 618,550 | $1,925 萬 | 0.02% | −2,248−0.4% | 減碼 |
| Millennium Management LLC | 635,370 | $1,917 萬 | 0.02% | −138,845−17.9% | 減碼 |
| Royal Bank of Canada | 616,081 | $1,859 萬 | 0.00% | −27,111−4.2% | 減碼 |
| Pinnacle Associates Ltd | 608,517 | $1,836 萬 | 0.27% | +60,875+11.1% | 加碼 |
| Groupama Asset Managment | 569,211 | $1,823 萬 | 0.36% | +52,020+10.1% | 加碼 |
| AXA S.A. | 566,486 | $1,709 萬 | 0.06% | −38,859−6.4% | 減碼 |
| Schonfeld Strategic Advisors LLC | 560,359 | $1,691 萬 | 0.11% | +188,978+50.9% | 加碼 |
| Bank of New York Mellon Corp | 544,633 | $1,643 萬 | 0.00% | −71,438−11.6% | 減碼 |
| Eversept Partners, LP | 517,021 | $1,560 萬 | 1.77% | +302,069+140.5% | 加碼 |
| Teacher Retirement System of Texas | 500,451 | $1,510 萬 | 0.06% | +434,659+660.7% | 加碼 |
| Standard Life Aberdeen plc | 446,197 | $1,350 萬 | 0.03% | +44,696+11.1% | 加碼 |
| Citigroup Inc | 426,480 | $1,287 萬 | 0.01% | +257,325+152.1% | 加碼 |
| JPMorgan Chase & Co | 421,511 | $1,272 萬 | 0.00% | +5,592+1.3% | 加碼 |
| C WorldWide Group Holding A/S | 400,000 | $1,207 萬 | 0.15% | 00.0% | 不變 |
| Voloridge Investment Management, LLC | 377,204 | $1,138 萬 | 0.04% | +60,261+19.0% | 加碼 |
| Ameriprise Financial Inc | 360,188 | $1,087 萬 | 0.00% | −27,260−7.0% | 減碼 |
| Baker Bros. Advisors LP | 357,915 | $1,080 萬 | 0.12% | 00.0% | 不變 |
| Barclays PLC | 353,937 | $1,068 萬 | 0.00% | −242,135−40.6% | 減碼 |
| Legal & General Group Plc | 338,462 | $1,021 萬 | 0.00% | +170,382+101.4% | 加碼 |
| Sovran Advisors, LLC | 328,904 | $934.1 萬 | 1.21% | +157,092+91.4% | 加碼 |
| Nuveen, LLC | 308,777 | $931.6 萬 | 0.00% | +308,777 | 新進 |
| BNP Paribas Arbitrage, SA | 308,293 | $930.1 萬 | 0.01% | +53,772+21.1% | 加碼 |
| J. Goldman & Co LP | 307,770 | $928.5 萬 | 0.33% | −299,729−49.3% | 減碼 |
| Squarepoint Ops LLC | 305,373 | $921.3 萬 | 0.02% | +138,905+83.4% | 加碼 |
| Point72 Asset Management, L.P. | 287,204 | $866.5 萬 | 0.02% | +287,204 | 新進 |
| Sector Gamma AS | 285,842 | $862.4 萬 | 2.76% | +50,000+21.2% | 加碼 |
| Swiss National Bank | 275,300 | $830.6 萬 | 0.01% | −3,900−1.4% | 減碼 |
| Privium Fund Management B.V. | 267,594 | $807.3 萬 | 2.10% | +800+0.3% | 加碼 |
| Wells Fargo & Company | 256,233 | $773.1 萬 | 0.00% | −74,776−22.6% | 減碼 |
| Great Point Partners LLC | 250,000 | $754.3 萬 | 4.10% | −255,007−50.5% | 減碼 |
| CI Private Wealth, LLC | 237,133 | $715.4 萬 | 0.01% | −2,030−0.8% | 減碼 |
| Nomura Holdings Inc | 236,426 | $713.3 萬 | 0.04% | −120,829−33.8% | 減碼 |
| Orion Investment Co | 215,290 | $649.5 萬 | 2.67% | −710−0.3% | 減碼 |
| Artisan Partners Limited Partnership | 203,178 | $613.0 萬 | 0.01% | −49,457−19.6% | 減碼 |
| Stifel Financial Corp | 200,942 | $606.2 萬 | 0.01% | −10,551−5.0% | 減碼 |
| California Public Employees Retirement System | 191,004 | $576.3 萬 | 0.00% | −1,126−0.6% | 減碼 |
| Rhumbline Advisers | 188,216 | $567.8 萬 | 0.01% | −3,677−1.9% | 減碼 |
| Tocqueville Asset Management L.P. | 187,395 | $565.4 萬 | 0.09% | −164,745−46.8% | 減碼 |
| Sicart Associates LLC | 185,646 | $560.1 萬 | 1.94% | −175−0.1% | 減碼 |
| GW&K Investment Management, LLC | 182,309 | $550.0 萬 | 0.05% | −4,911−2.6% | 減碼 |
| Rafferty Asset Management, LLC | 176,248 | $531.7 萬 | 0.02% | −61,089−25.7% | 減碼 |
| Susquehanna Fundamental Investments, LLC | 158,609 | $478.5 萬 | 0.08% | −54,406−25.5% | 減碼 |
| Aquatic Capital Management LLC | 156,157 | $471.1 萬 | 0.12% | −73,859−32.1% | 減碼 |
| Sonora Investment Management Group, LLC | 154,147 | $465.1 萬 | 0.37% | +5,371+3.6% | 加碼 |
| Renaissance Technologies LLC | 153,514 | $463.2 萬 | 0.01% | −52,000−25.3% | 減碼 |
| State Board of Administration of Florida Retirement System | 152,315 | $459.5 萬 | 0.01% | 00.0% | 不變 |
| BLB&B Advisors, LLC | 152,200 | $459.2 萬 | 0.23% | +150+0.1% | 加碼 |
| Kennedy Capital Management, Inc. | 150,424 | $453.8 萬 | 0.11% | −72,854−32.6% | 減碼 |
| Tang Capital Management LLC | 150,000 | $452.6 萬 | 0.25% | 00.0% | 不變 |
| Raymond James Financial Inc | 148,690 | $448.6 萬 | 0.00% | +43,071+40.8% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 143,870 | $434.1 萬 | 0.01% | +143,870 | 新進 |
| Sumitomo Mitsui Trust Holdings, Inc. | 142,433 | $429.7 萬 | 0.00% | −14,224−9.1% | 減碼 |
| Nikko Asset Management Americas, Inc. | 142,433 | $429.6 萬 | 0.06% | −14,224−9.1% | 減碼 |
| Exome Asset Management LLC | 135,616 | $409.2 萬 | 3.66% | +74,249+121.0% | 加碼 |
| California State Teachers Retirement System | 132,238 | $399.0 萬 | 0.00% | −1,664−1.2% | 減碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 129,273 | $390.0 萬 | 0.02% | +3,884+3.1% | 加碼 |
| Edmond de Rothschild Holding S.A. | 124,200 | $374.7 萬 | 0.07% | +124,200 | 新進 |
| American Century Companies Inc | 116,768 | $352.3 萬 | 0.00% | +116,768 | 新進 |
| State of Wisconsin Investment Board | 108,316 | $326.8 萬 | 0.01% | +7,085+7.0% | 加碼 |
| Neuberger Berman Group LLC | 102,473 | $309.2 萬 | 0.00% | +5,842+6.0% | 加碼 |
| Alliancebernstein L.P. | 100,749 | $304.0 萬 | 0.00% | +48,613+93.2% | 加碼 |
| PDT Partners, LLC | 96,056 | $289.8 萬 | 0.21% | +67,062+231.3% | 加碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $287.2 萬 | 0.01% | 00.0% | 不變 |
| DCF Advisers, LLC | 95,000 | $286.6 萬 | 1.54% | +12,118+14.6% | 加碼 |
| Walleye Capital LLC | 94,990 | $286.6 萬 | 0.03% | +78,735+484.4% | 加碼 |