Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 1 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 344
- 較 2024 年第 4 季 −6 家
- 持有股數
- 1.67 億
- 較 2024 年第 4 季 +668.6 萬 (+4.2%)
- 總市值
- $50.3 億
- 較 2024 年第 4 季 −$5.65 億 (−10.1%)
- 新進機構
- 54
- 另有 102 家加碼
- 清倉機構
- 60
- 另有 123 家減碼
另有 6 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 1 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2024 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| UBS Oconnor LLC | 90,779 | $273.9 萬 | 0.07% | +30,199+49.8% | 加碼 |
| Nicola Wealth Management Ltd. | 87,000 | $262.5 萬 | 0.26% | 00.0% | 不變 |
| Deutsche Bank AG | 84,810 | $255.9 萬 | 0.00% | −7,091−7.7% | 減碼 |
| Manufacturers Life Insurance Company, The | 83,440 | $251.7 萬 | 0.00% | −202,839−70.9% | 減碼 |
| Jump Financial, LLC | 81,321 | $245.3 萬 | 0.04% | +41,584+104.6% | 加碼 |
| Rhenman & Partners Asset Management AB | 81,000 | $244.4 萬 | 0.28% | −131,500−61.9% | 減碼 |
| New York State Common Retirement Fund | 78,261 | $236.1 萬 | 0.00% | −6,000−7.1% | 減碼 |
| HSBC Holdings PLC | 74,833 | $222.2 萬 | 0.00% | −8,222−9.9% | 減碼 |
| Susquehanna International Group, LLP | 71,811 | $216.7 萬 | 0.00% | +45,747+175.5% | 加碼 |
| Treasurer of the State of North Carolina | 71,593 | $216.0 萬 | 0.01% | +2,790+4.1% | 加碼 |
| SEI Investments Co | 71,558 | $215.9 萬 | 0.00% | +1,467+2.1% | 加碼 |
| Granite Investment Partners, LLC | 68,434 | $206.5 萬 | 0.10% | −5,432−7.4% | 減碼 |
| Janus Henderson Group PLC | 63,877 | $199.0 萬 | 0.00% | 00.0% | 不變 |
| Simplex Trading, LLC | 64,581 | $194.8 萬 | 0.07% | +64,581 | 新進 |
| Sphera Funds Management Ltd. | 63,821 | $192.5 萬 | 0.47% | 00.0% | 不變 |
| Voya Investment Management LLC | 63,767 | $192.4 萬 | 0.00% | −28,764−31.1% | 減碼 |
| Lazard Asset Management LLC | 60,758 | $183.2 萬 | 0.00% | +54,201+826.6% | 加碼 |
| State of New Jersey Common Pension Fund D | 60,662 | $183.0 萬 | 0.01% | −2,544−4.0% | 減碼 |
| Avidity Partners Management LP | 60,000 | $181.0 萬 | 0.37% | +60,000 | 新進 |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $179.9 萬 | 0.01% | 00.0% | 不變 |
| Capital Fund Management S.A. | 58,014 | $175.0 萬 | 0.02% | +58,014 | 新進 |
| Police & Firemen's Retirement System of New Jersey | 57,549 | $173.6 萬 | 0.02% | +854+1.5% | 加碼 |
| Davenport & Co LLC | 56,393 | $170.1 萬 | 0.01% | −6,347−10.1% | 減碼 |
| Ensign Peak Advisors, Inc | 55,100 | $166.2 萬 | 0.00% | +1,780+3.3% | 加碼 |
| Jane Street Group, LLC | 54,117 | $163.3 萬 | 0.00% | −110,517−67.1% | 減碼 |
| Erste Asset Management GmbH | 51,300 | $159.8 萬 | 0.02% | 00.0% | 不變 |
| Verition Fund Management LLC | 52,287 | $157.7 萬 | 0.01% | −147,897−73.9% | 減碼 |
| Public Employees Retirement System of Ohio | 48,177 | $145.3 萬 | 0.01% | −5,571−10.4% | 減碼 |
| Schroder Investment Management Group | 45,950 | $143.1 萬 | 0.00% | −54,709−54.4% | 減碼 |
| Readystate Asset Management LP | 46,394 | $140.0 萬 | 0.07% | +46,394 | 新進 |
| Great West Life Assurance Co | 43,853 | $132.6 萬 | 0.00% | +4,639+11.8% | 加碼 |
| Handelsbanken Fonder AB | 43,211 | $130.4 萬 | 0.01% | −600−1.4% | 減碼 |
| Raiffeisen Bank International AG | 41,754 | $129.9 萬 | 0.02% | +40,000+2,280.5% | 加碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $126.7 萬 | 0.16% | 00.0% | 不變 |
| Guggenheim Capital LLC | 41,414 | $124.9 萬 | 0.01% | +6,041+17.1% | 加碼 |
| Point72 (DIFC) Ltd | 41,347 | $124.7 萬 | 0.12% | +41,347 | 新進 |
| Arizona State Retirement System | 40,687 | $122.8 萬 | 0.01% | −460−1.1% | 減碼 |
| Blair William & Co | 38,381 | $115.8 萬 | 0.00% | −1,501−3.8% | 減碼 |
| Prelude Capital Management, LLC | 37,772 | $114.0 萬 | 0.11% | +22,177+142.2% | 加碼 |
| Grandfield & Dodd, LLC | 37,761 | $113.9 萬 | 0.07% | +1,874+5.2% | 加碼 |
| Capital Counsel LLC | 37,080 | $111.9 萬 | 0.05% | 00.0% | 不變 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 36,509 | $110.1 萬 | 0.00% | +187+0.5% | 加碼 |
| Creative Planning | 36,122 | $109.0 萬 | 0.00% | −10,681−22.8% | 減碼 |
| SummitTX Capital, L.P. | 35,103 | $105.9 萬 | 0.05% | +35,103 | 新進 |
| Allostery Investments LP | 35,000 | $105.6 萬 | 1.52% | −30,000−46.2% | 減碼 |
| Profund Advisors LLC | 34,887 | $105.3 萬 | 0.05% | −8,672−19.9% | 減碼 |
| Private Advisor Group, LLC | 34,531 | $104.2 萬 | 0.01% | −6,142−15.1% | 減碼 |
| Pathstone Holdings, LLC | 34,372 | $102.9 萬 | 0.00% | +8,314+31.9% | 加碼 |
| Mariner, LLC | 33,483 | $101.0 萬 | 0.00% | +5,822+21.0% | 加碼 |
| China Universal Asset Management Co., Ltd. | 31,886 | $96.2 萬 | 0.09% | −1,594−4.8% | 減碼 |
| Liontrust Investment Partners LLP | 30,390 | $91.7 萬 | 0.01% | −11,231−27.0% | 減碼 |
| Axq Capital, LP | 30,104 | $90.8 萬 | 0.36% | +30,104 | 新進 |
| Alpine Global Management, LLC | 28,097 | $84.8 萬 | 0.22% | +28,097 | 新進 |
| KLP Kapitalforvaltning AS | 27,400 | $82.7 萬 | 0.00% | −1,800−6.2% | 減碼 |
| ExodusPoint Capital Management, LP | 26,261 | $79.2 萬 | 0.01% | +26,261 | 新進 |
| HRT Financial LP | 25,824 | $77.9 萬 | 0.00% | +25,824 | 新進 |
| NEOS Investment Management LLC | 25,141 | $75.9 萬 | 0.01% | −31,703−55.8% | 減碼 |
| Tema ETFs LLC | 25,141 | $75.9 萬 | 0.23% | −31,703−55.8% | 減碼 |
| BlueCrest Capital Management Ltd | 24,800 | $74.8 萬 | 0.12% | −1,400−5.3% | 減碼 |
| Teachers Retirement System of the State of Kentucky | 24,083 | $72.7 萬 | 0.01% | 00.0% | 不變 |
| LPL Financial LLC | 23,966 | $72.3 萬 | 0.00% | −16,410−40.6% | 減碼 |
| Castle Hook Partners LP | 23,940 | $72.2 萬 | 0.02% | 00.0% | 不變 |
| Brevan Howard Capital Management LP | 22,973 | $69.3 萬 | 0.02% | +1,607+7.5% | 加碼 |
| Jefferies Financial Group Inc. | 22,841 | $68.9 萬 | 0.01% | +460+2.1% | 加碼 |
| Bleakley Financial Group, LLC | 22,284 | $67.2 萬 | 0.02% | +5,342+31.5% | 加碼 |
| Daiwa Securities Group Inc. | 22,141 | $66.7 萬 | 0.00% | +21,600+3,992.6% | 加碼 |
| Toroso Investments, LLC | 21,833 | $65.9 萬 | 0.01% | +4,426+25.4% | 加碼 |
| Nicollet Investment Management, Inc. | 21,451 | $64.7 萬 | 0.23% | +1,665+8.4% | 加碼 |
| Bridgefront Capital, LLC | 20,528 | $61.9 萬 | 0.18% | −1,274−5.8% | 減碼 |
| Xponance, Inc. | 20,319 | $61.3 萬 | 0.01% | +980+5.1% | 加碼 |
| SG Americas Securities, LLC | 20,050 | $60.5 萬 | 0.00% | −3,877−16.2% | 減碼 |
| Victory Capital Management Inc | 18,641 | $56.2 萬 | 0.00% | +637+3.5% | 加碼 |
| NBT Bank N A | 17,050 | $51.4 萬 | 0.04% | 00.0% | 不變 |
| Virginia Retirement Systems Et Al | 16,522 | $49.8 萬 | 0.00% | +16,522 | 新進 |
| E Fund Management Co., Ltd. | 16,471 | $49.7 萬 | 0.02% | −397−2.4% | 減碼 |
| Commonwealth Equity Services, LLC | 16,398 | $49.5 萬 | 0.00% | −5,428−24.9% | 減碼 |
| Twinbeech Capital LP | 15,938 | $48.1 萬 | 0.01% | +15,938 | 新進 |
| Public Employees Retirement Association of Colorado | 15,589 | $47.0 萬 | 0.00% | 00.0% | 不變 |
| Envestnet Asset Management Inc | 15,039 | $45.4 萬 | 0.00% | −37,649−71.5% | 減碼 |
| Jones Financial Companies LLLP | 13,735 | $42.8 萬 | 0.00% | +4,397+47.1% | 加碼 |
| North Star Asset Management Inc | 13,610 | $41.1 萬 | 0.02% | −30−0.2% | 減碼 |
| Significant Wealth Partners LLC | 13,605 | $41.0 萬 | 0.21% | +2,700+24.8% | 加碼 |
| Westmount Partners, LLC | 12,961 | $39.1 萬 | 0.12% | −501−3.7% | 減碼 |
| Point72 Hong Kong Ltd | 12,862 | $38.8 萬 | 0.03% | +12,862 | 新進 |
| Horizon Kinetics Asset Management LLC | 12,476 | $37.6 萬 | 0.00% | 00.0% | 不變 |
| XTX Topco Ltd | 12,404 | $37.4 萬 | 0.02% | −12,958−51.1% | 減碼 |
| Northwestern Mutual Wealth Management Co | 12,358 | $37.3 萬 | 0.00% | +1,031+9.1% | 加碼 |
| Intech Investment Management LLC | 12,207 | $36.8 萬 | 0.00% | +12,207 | 新進 |
| Brown Advisory Inc | 12,026 | $36.3 萬 | 0.00% | −704−5.5% | 減碼 |
| SIH Partners, LLLP | 11,999 | $36.2 萬 | 0.03% | +11,999 | 新進 |
| FORA Capital, LLC | 11,570 | $34.9 萬 | 0.04% | +11,570 | 新進 |
| Twin Tree Management, LP | 11,385 | $34.3 萬 | 0.01% | −77,515−87.2% | 減碼 |
| Wiley Bros.-Aintree Capital, LLC | 11,004 | $34.3 萬 | 0.00% | +687+6.7% | 加碼 |
| Plancorp, LLC | 11,128 | $33.6 萬 | 0.01% | 00.0% | 不變 |
| The PNC Financial Services Group, Inc. | 10,987 | $33.1 萬 | 0.00% | −7−0.1% | 減碼 |
| Suvretta Capital Management, LLC | 10,800 | $32.6 萬 | 0.01% | 00.0% | 不變 |
| Annis Gardner Whiting Capital Advisors, LLC | 10,736 | $32.4 萬 | 0.14% | 00.0% | 不變 |
| Amalgamated Bank | 10,573 | $31.9 萬 | 0.00% | +281+2.7% | 加碼 |
| Harbor Advisors LLC | 10,500 | $31.7 萬 | 0.06% | 00.0% | 不變 |
| Principal Financial Group Inc | 10,447 | $31.5 萬 | 0.00% | −3,169−23.3% | 減碼 |