Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、7 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2022 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2022/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 339
- 較 2022 年第 3 季 −4 家
- 持有股數
- 1.31 億
- 較 2022 年第 3 季 +477.0 萬 (+3.8%)
- 總市值
- $49.3 億
- 較 2022 年第 3 季 −$6.31 億 (−11.3%)
- 新進機構
- 50
- 另有 115 家加碼
- 清倉機構
- 54
- 另有 107 家減碼
另有 7 家機構在 2022 年第 3 季持有、還沒有申報 2022 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2022 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2022 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 21,307,519 | $8.05 億 | 0.08% | +16,360+0.1% | 加碼 |
| Vanguard Group Inc | 13,546,694 | $5.12 億 | 0.01% | +740,671+5.8% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 11,678,259 | $4.41 億 | 0.34% | +521,564+4.7% | 加碼 |
| Bellevue Group AG | 9,743,900 | $3.68 億 | 4.88% | +280,500+3.0% | 加碼 |
| BlackRock Inc. | 9,079,557 | $3.43 億 | 0.01% | +143,495+1.6% | 加碼 |
| Clearbridge Investments, LLC | 5,425,642 | $2.05 億 | 0.20% | −348,250−6.0% | 減碼 |
| Price T Rowe Associates Inc | 4,292,431 | $1.62 億 | 0.03% | −504,701−10.5% | 減碼 |
| State Street Corp | 4,218,729 | $1.59 億 | 0.01% | +457,774+12.2% | 加碼 |
| Tweedy, Browne Co LLC | 3,541,136 | $1.34 億 | 7.12% | +818,148+30.0% | 加碼 |
| ARK Investment Management LLC大師方舟投資 | 2,673,538 | $1.01 億 | 0.88% | −1,039,569−28.0% | 減碼 |
| Geode Capital Management, LLC | 2,012,723 | $7,602 萬 | 0.01% | +111,580+5.9% | 加碼 |
| OrbiMed Advisors LLC | 1,993,600 | $7,530 萬 | 1.44% | +1,224,700+159.3% | 加碼 |
| Camber Capital Management LP | 1,925,000 | $7,271 萬 | 2.54% | 00.0% | 不變 |
| First Trust Advisors LP | 1,780,933 | $6,726 萬 | 0.08% | −296,327−14.3% | 減碼 |
| Macquarie Group Ltd | 1,491,687 | $5,634 萬 | 0.07% | +657,646+78.9% | 加碼 |
| Norges Bank | 1,296,647 | $4,897 萬 | 0.01% | +105,896+8.9% | 加碼 |
| Charles Schwab Investment Management Inc | 1,256,268 | $4,745 萬 | 0.02% | +53,922+4.5% | 加碼 |
| Deep Track Capital, LP | 1,205,773 | $4,554 萬 | 1.99% | +1,205,773 | 新進 |
| Renaissance Technologies LLC | 1,178,814 | $4,452 萬 | 0.06% | +311,100+35.9% | 加碼 |
| BVF Inc | 1,121,809 | $4,237 萬 | 1.79% | −1,751,144−61.0% | 減碼 |
| Swedbank AB | 1,021,429 | $3,858 萬 | 0.08% | 00.0% | 不變 |
| JPMorgan Chase & Co | 970,310 | $3,665 萬 | 0.01% | +41,558+4.5% | 加碼 |
| Morgan Stanley | 936,709 | $3,538 萬 | 0.00% | +240,171+34.5% | 加碼 |
| Goldman Sachs Group Inc | 922,411 | $3,484 萬 | 0.01% | −368,154−28.5% | 減碼 |
| Thrivent Financial for Lutherans | 919,332 | $3,472 萬 | 0.09% | +10,853+1.2% | 加碼 |
| TD Asset Management Inc | 779,495 | $2,944 萬 | 0.04% | −24,588−3.1% | 減碼 |
| Jacobs Levy Equity Management, Inc | 689,721 | $2,605 萬 | 0.18% | +177,746+34.7% | 加碼 |
| Northern Trust Corp | 639,689 | $2,416 萬 | 0.01% | +16,049+2.6% | 加碼 |
| Bank of America Corp | 637,313 | $2,407 萬 | 0.00% | +77,357+13.8% | 加碼 |
| Two Sigma Advisers, LP | 634,911 | $2,398 萬 | 0.07% | −22,600−3.4% | 減碼 |
| Wells Fargo & Company | 608,040 | $2,297 萬 | 0.01% | −81,832−11.9% | 減碼 |
| Bank of New York Mellon Corp | 573,798 | $2,167 萬 | 0.00% | −5,615−1.0% | 減碼 |
| AXA S.A. | 521,570 | $1,970 萬 | 0.07% | +339,214+186.0% | 加碼 |
| Barclays PLC | 507,311 | $1,916 萬 | 0.02% | +2,823+0.6% | 加碼 |
| Royal Bank of Canada | 506,845 | $1,915 萬 | 0.01% | +70,021+16.0% | 加碼 |
| Pinnacle Associates Ltd | 494,750 | $1,869 萬 | 0.41% | −6,140−1.2% | 減碼 |
| Allspring Global Investments Holdings, LLC | 488,063 | $1,843 萬 | 0.03% | +481,018+6,827.8% | 加碼 |
| Candriam Luxembourg S.C.A. | 465,700 | $1,759 萬 | 0.12% | +14,349+3.2% | 加碼 |
| Dimensional Fund Advisors LP | 458,444 | $1,731 萬 | 0.01% | −102,484−18.3% | 減碼 |
| Assenagon Asset Management S.A. | 441,802 | $1,669 萬 | 0.07% | −10,958−2.4% | 減碼 |
| Nomura Holdings Inc | 400,057 | $1,510 萬 | 0.15% | +12,149+3.1% | 加碼 |
| Citadel Advisors LLC | 395,546 | $1,494 萬 | 0.02% | −22,686−5.4% | 減碼 |
| Pictet Asset Management SA | 373,586 | $1,411 萬 | 0.02% | +96,609+34.9% | 加碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 336,732 | $1,272 萬 | 0.01% | −100,444−23.0% | 減碼 |
| Nikko Asset Management Americas, Inc. | 336,732 | $1,271 萬 | 0.18% | −100,444−23.0% | 減碼 |
| Baillie Gifford & Co | 333,788 | $1,261 萬 | 0.01% | +8,946+2.8% | 加碼 |
| Qube Research & Technologies Ltd | 330,724 | $1,249 萬 | 0.08% | +319,027+2,727.4% | 加碼 |
| California Public Employees Retirement System | 329,837 | $1,246 萬 | 0.01% | +6,251+1.9% | 加碼 |
| Nuveen Asset Management, LLC | 323,178 | $1,221 萬 | 0.00% | −16,106−4.7% | 減碼 |
| Invesco Ltd. | 322,447 | $1,218 萬 | 0.00% | +27,248+9.2% | 加碼 |
| Altrinsic Global Advisors LLC | 319,174 | $1,206 萬 | 0.51% | +157,928+97.9% | 加碼 |
| Swiss National Bank | 308,400 | $1,165 萬 | 0.01% | +5,800+1.9% | 加碼 |
| ExodusPoint Capital Management, LP | 304,390 | $1,150 萬 | 0.18% | +297,973+4,643.5% | 加碼 |
| CI Private Wealth, LLC | 302,677 | $1,143 萬 | 0.04% | +302,677 | 新進 |
| D. E. Shaw & Co., Inc. | 299,231 | $1,130 萬 | 0.02% | +89,786+42.9% | 加碼 |
| Stifel Financial Corp | 269,744 | $1,019 萬 | 0.02% | −30,269−10.1% | 減碼 |
| Redmile Group, LLC | 266,187 | $1,005 萬 | 0.41% | −141,472−34.7% | 減碼 |
| Schonfeld Strategic Advisors LLC | 265,798 | $1,004 萬 | 0.08% | +58,126+28.0% | 加碼 |
| Sicart Associates LLC | 246,258 | $930.1 萬 | 3.28% | −7,718−3.0% | 減碼 |
| Bank of Montreal | 221,978 | $921.4 萬 | 0.01% | −101,551−31.4% | 減碼 |
| Eversept Partners, LP | 240,975 | $910.2 萬 | 0.87% | +39,142+19.4% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 230,577 | $870.9 萬 | 0.05% | +1,516+0.7% | 加碼 |
| Man Group plc | 230,525 | $870.7 萬 | 0.03% | +52,928+29.8% | 加碼 |
| Raymond James & Associates | 225,470 | $851.6 萬 | 0.01% | −12,698−5.3% | 減碼 |
| Hudson Bay Capital Management LP | 225,000 | $849.8 萬 | 0.10% | +25,200+12.6% | 加碼 |
| Rafferty Asset Management, LLC | 218,979 | $827.1 萬 | 0.07% | +67,005+44.1% | 加碼 |
| Two Sigma Investments, LP | 201,267 | $760.2 萬 | 0.02% | −91,727−31.3% | 減碼 |
| Tang Capital Management LLC | 200,000 | $755.4 萬 | 1.10% | 00.0% | 不變 |
| Jefferies Financial Group Inc. | 197,009 | $744.1 萬 | 0.13% | +197,009 | 新進 |
| BNP Paribas Arbitrage, SA | 191,947 | $725.0 萬 | 0.02% | +59,207+44.6% | 加碼 |
| Fred Alger Management, LLC | 190,353 | $719.0 萬 | 0.04% | +47,831+33.6% | 加碼 |
| Russell Investments Group, Ltd. | 190,298 | $718.8 萬 | 0.01% | +97,978+106.1% | 加碼 |
| Credit Suisse AG | 184,302 | $696.1 萬 | 0.01% | +29,604+19.1% | 加碼 |
| Squarepoint Ops LLC | 181,007 | $683.7 萬 | 0.05% | +88,953+96.6% | 加碼 |
| UBS Asset Management Americas Inc | 175,796 | $664.0 萬 | 0.00% | −103,828−37.1% | 減碼 |
| California State Teachers Retirement System | 167,875 | $634.1 萬 | 0.01% | +1,950+1.2% | 加碼 |
| Rhumbline Advisers | 165,163 | $623.8 萬 | 0.01% | +9,449+6.1% | 加碼 |
| Tocqueville Asset Management L.P. | 161,569 | $610.2 萬 | 0.12% | −825−0.5% | 減碼 |
| UBS Group AG | 161,471 | $609.9 萬 | 0.00% | +100,161+163.4% | 加碼 |
| Natixis | 159,678 | $603.1 萬 | 0.04% | +25,597+19.1% | 加碼 |
| Sonora Investment Management Group, LLC | 156,115 | $589.6 萬 | 0.54% | −908−0.6% | 減碼 |
| State Board of Administration of Florida Retirement System | 155,145 | $586.0 萬 | 0.01% | −8,110−5.0% | 減碼 |
| DekaBank Deutsche Girozentrale | 153,000 | $569.9 萬 | 0.02% | +28,224+22.6% | 加碼 |
| BLB&B Advisors, LLC | 148,960 | $562.6 萬 | 0.44% | −110−0.1% | 減碼 |
| Privium Fund Management B.V. | 148,807 | $555.8 萬 | 2.11% | 00.0% | 不變 |
| Sector Gamma AS | 141,373 | $534.0 萬 | 1.22% | −22,850−13.9% | 減碼 |
| Parkman Healthcare Partners LLC | 141,115 | $533.0 萬 | 1.42% | −100,830−41.7% | 減碼 |
| New York State Common Retirement Fund | 140,500 | $530.7 萬 | 0.01% | −2,400−1.7% | 減碼 |
| Kennedy Capital Management, Inc. | 139,181 | $525.7 萬 | 0.15% | −5,614−3.9% | 減碼 |
| Peregrine Capital Management LLC | 131,711 | $497.5 萬 | 0.16% | +8,315+6.7% | 加碼 |
| Citigroup Inc | 129,129 | $487.7 萬 | 0.01% | −47,863−27.0% | 減碼 |
| State of Wisconsin Investment Board | 128,227 | $484.3 萬 | 0.02% | −1,627−1.3% | 減碼 |
| Cubist Systematic Strategies, LLC | 128,070 | $483.7 萬 | 0.04% | +57,662+81.9% | 加碼 |
| Legal & General Group Plc | 127,088 | $480.0 萬 | 0.00% | −1,365−1.1% | 減碼 |
| M28 Capital Management LP | 126,300 | $477.0 萬 | 4.55% | +126,300 | 新進 |
| Millennium Management LLC | 115,506 | $436.3 萬 | 0.00% | +96,577+510.2% | 加碼 |
| Eventide Asset Management, LLC | 110,000 | $415.5 萬 | 0.08% | 00.0% | 不變 |
| Allianz Asset Management GmbH | 102,487 | $387.1 萬 | 0.01% | +73,607+254.9% | 加碼 |
| Alberta Investment Management Corp | 101,426 | $383.1 萬 | 0.03% | +101,426 | 新進 |
| Public Sector Pension Investment Board | 98,000 | $370.1 萬 | 0.03% | +98,000 | 新進 |